| Definition | Ruegeria sp. TM1040, complete genome. |
|---|---|
| Accession | NC_008044 |
| Length | 3,200,938 |
Click here to switch to the map view.
The map label for this gene is icd [H]
Identifier: 99080318
GI number: 99080318
Start: 497149
End: 499365
Strand: Reverse
Name: icd [H]
Synonym: TM1040_0477
Alternate gene names: 99080318
Gene position: 499365-497149 (Counterclockwise)
Preceding gene: 99080320
Following gene: 99080317
Centisome position: 15.6
GC content: 61.61
Gene sequence:
>2217_bases ATGGCAGAAAATTCAACGCCGGACATTTTGTATACCATTGTAGACGAAGCGCCCGAGCTGGCCTCGGCATCTTTCCTGCC GATCATCCGCAAATTTGCGGATGCTGCCGGTGTCAGCGTTGGCACAAAGGACATTTCGCTGGCCGCACGCATTATCGCGA CCTTCCCGGAGAACCTCACCGAAGAGCAGCGCCAAAGCGATGACCTCGCCGCGCTGGGCGAGCTGGTGAAGACCCCCGAC GCAAATGTCATCAAACTGCCCAACATCTCTGCATCCGTGCCCCAGCTGGTGGCCGCGATCGAGGAACTGCAGGCGCAGGG GTACAAGCTGCCCGACTACCCCTACGAGCCCGCAACCGACGCGGAAAAGGAAATCCGCGCCCGCTACGACACCATCAAGG GCTCCGCGGTGAACCCAGTCCTGCGCGAAGGCAACTCGGACCGTCGTTCGGCCAAAGCCGTGAAGAACTACGCTCAGAAC AACCCGCATTCGATGGGCGCATGGTCTGGCGACAGCAAGACCAAAGTCTCGTCGATGCCCGGCAACGACTTTTATGCCAA CGAGAAATCCGCCACCATTTCCGCCGAGCAGGCCGGTGACGCGAAGATCGAATTTGTCGCAAAAGACGGGTCCGTCACCG TTCTGAAAGACGGCTGGCCGCTGGCAGAAGGCACGGTTGCCGATGCGACCTTCATGTCCGCCAAAGCGCTCGCCGCGTTC CTGTCTGGCGCGATCGAGGATACCAAGGCGGACGGCACCATGTTCTCGCTGCACATGAAGGCCACCATGATGAAGGTCTC CGACCCGATCATCTTTGGCCACGCGGTCAAAGCCTGGCTCGGCCCTGTGTGGGATAAACACGGCGCCGCAATTGCTGCCG CAGGTGGGTCGCCGAACTCCGGTCTGGGTGCGGTTCTGGCCGCCATCGACAGCCTGCCCAACGCAGATGAGATCAAATCC GAGATCGCCGCGCTCGAACGCCCCTCCATGTATATGGTGGACAGCGACAAGGGTATCACCAACCTGCATGTGCCCTCCGA CGTGATCATCGATGCCTCCATGCCGGCCGTGATCCGTGCTGGCGGTAAGGGCTGGGACGAGACCGGCGCCAAGGGCGACA CCAACTGCGTGATCCCCGACCGCTGCTACTCCACCGTCTATGACGAGACCATCAACTTCTTCAAAGCCAATGGCGCGCTC GACGTGACCACTGCCGGTTCGGTCGCAAACGTCGGCTTGATGGCGCAAAAGGCGGAAGAGTATGGCTCGCACCCGACGAC CTTCGAAGCCCCGGCAGACGGCGAGATCCGCGTTATTCTGGCCAATGGCGAGACCCTGCACAGCCACGAAGTCGAGGCCG GCGACATCTGGCGCGCCTGCACCGTGAAAAAGGCTCCAATCGAGAACTGGATTCAACTGGCTTTGGACCGTCAGCGCCTG ACCGGGTCCGAGGCGATCTTCTGGCTGGACGCAAACCGCGCCCATGACGCAGAGCTGATCAAATACGTCAAACCCGCGCT TGATGCGGCTGGCGTCGCCGACAAGTTCCTGATCATGGCGCCGCGCGAAGCCACCCGTCAGAGCCTCGAGACCATCACTG CGGGCAAGGACAGCATCGCCATCACCGGCAACGTGCTGCGCGACTACCTGACCGACCTGTTCCCGATCCTCGAGCTTGGC ACCTCGGCCAAGATGCTGTCGATTGTGAAGCTGATGAACGGCGGCGGCTTGTTTGAGACCGGCGCAGGCGGTTCCGCGCC CAAACACGTGCAGCAACTGGTTGAGGAAAACCACCTGCGTTGGGACTCCATGGGTGAGTTCTGCGCTCTGGGCGAAAGCC TGAAGTTCCTCGCCGATGTCAAAGGCAACGAGAAGGCAGGCGTGCTTGGCGCAGCTGCCGAGGTTGCGACCCAAGGCATC CTCGACAACAACAAATCGCCCGAGCGCAAAGTCGGCCAGCCCGACAACCGCGACAGCCACTACTGGTTTGCCCGCTACTG GGCAGAAGCCCTCGCGGCACAGGGTGATGACGCGGAGCTGGCCGCGCATTTCAAACCGATTGCCGAGGCTCTTGCCTCCA ACGAAGCGGCGATTCTGTCTGAACTCGCCGCCGCTCAGGGAGGCGCAGCCGACATCGGTGGCTATTACCACCCCTCCGTT GAAAAGAAGGCCGCCGTCATGCGCCCCTCTGCAACCCTCAACGGCATCATCGGCTGA
Upstream 100 bases:
>100_bases GCCCCGCGCCCCCTGCCGGACAAGTATCAAGTGACGCGGCACACGCGCACCGAATTGACGACGAACAACAGCTTCCGAAT TCGCAGAAAGGTTGTGGAAC
Downstream 100 bases:
>100_bases GCCTGACCTCAGGATCAAAGTCCAAAAATCACAAGGCGCCCGGCACAGTCCGGGCGCTTTTTGCATGGTCAGAGGGGAAA CCCGCCTCTGTTCCACAGGT
Product: isocitrate dehydrogenase, NADP-dependent
Products: NA
Alternate protein names: IDH; Oxalosuccinate decarboxylase [H]
Number of amino acids: Translated: 738; Mature: 737
Protein sequence:
>738_residues MAENSTPDILYTIVDEAPELASASFLPIIRKFADAAGVSVGTKDISLAARIIATFPENLTEEQRQSDDLAALGELVKTPD ANVIKLPNISASVPQLVAAIEELQAQGYKLPDYPYEPATDAEKEIRARYDTIKGSAVNPVLREGNSDRRSAKAVKNYAQN NPHSMGAWSGDSKTKVSSMPGNDFYANEKSATISAEQAGDAKIEFVAKDGSVTVLKDGWPLAEGTVADATFMSAKALAAF LSGAIEDTKADGTMFSLHMKATMMKVSDPIIFGHAVKAWLGPVWDKHGAAIAAAGGSPNSGLGAVLAAIDSLPNADEIKS EIAALERPSMYMVDSDKGITNLHVPSDVIIDASMPAVIRAGGKGWDETGAKGDTNCVIPDRCYSTVYDETINFFKANGAL DVTTAGSVANVGLMAQKAEEYGSHPTTFEAPADGEIRVILANGETLHSHEVEAGDIWRACTVKKAPIENWIQLALDRQRL TGSEAIFWLDANRAHDAELIKYVKPALDAAGVADKFLIMAPREATRQSLETITAGKDSIAITGNVLRDYLTDLFPILELG TSAKMLSIVKLMNGGGLFETGAGGSAPKHVQQLVEENHLRWDSMGEFCALGESLKFLADVKGNEKAGVLGAAAEVATQGI LDNNKSPERKVGQPDNRDSHYWFARYWAEALAAQGDDAELAAHFKPIAEALASNEAAILSELAAAQGGAADIGGYYHPSV EKKAAVMRPSATLNGIIG
Sequences:
>Translated_738_residues MAENSTPDILYTIVDEAPELASASFLPIIRKFADAAGVSVGTKDISLAARIIATFPENLTEEQRQSDDLAALGELVKTPD ANVIKLPNISASVPQLVAAIEELQAQGYKLPDYPYEPATDAEKEIRARYDTIKGSAVNPVLREGNSDRRSAKAVKNYAQN NPHSMGAWSGDSKTKVSSMPGNDFYANEKSATISAEQAGDAKIEFVAKDGSVTVLKDGWPLAEGTVADATFMSAKALAAF LSGAIEDTKADGTMFSLHMKATMMKVSDPIIFGHAVKAWLGPVWDKHGAAIAAAGGSPNSGLGAVLAAIDSLPNADEIKS EIAALERPSMYMVDSDKGITNLHVPSDVIIDASMPAVIRAGGKGWDETGAKGDTNCVIPDRCYSTVYDETINFFKANGAL DVTTAGSVANVGLMAQKAEEYGSHPTTFEAPADGEIRVILANGETLHSHEVEAGDIWRACTVKKAPIENWIQLALDRQRL TGSEAIFWLDANRAHDAELIKYVKPALDAAGVADKFLIMAPREATRQSLETITAGKDSIAITGNVLRDYLTDLFPILELG TSAKMLSIVKLMNGGGLFETGAGGSAPKHVQQLVEENHLRWDSMGEFCALGESLKFLADVKGNEKAGVLGAAAEVATQGI LDNNKSPERKVGQPDNRDSHYWFARYWAEALAAQGDDAELAAHFKPIAEALASNEAAILSELAAAQGGAADIGGYYHPSV EKKAAVMRPSATLNGIIG >Mature_737_residues AENSTPDILYTIVDEAPELASASFLPIIRKFADAAGVSVGTKDISLAARIIATFPENLTEEQRQSDDLAALGELVKTPDA NVIKLPNISASVPQLVAAIEELQAQGYKLPDYPYEPATDAEKEIRARYDTIKGSAVNPVLREGNSDRRSAKAVKNYAQNN PHSMGAWSGDSKTKVSSMPGNDFYANEKSATISAEQAGDAKIEFVAKDGSVTVLKDGWPLAEGTVADATFMSAKALAAFL SGAIEDTKADGTMFSLHMKATMMKVSDPIIFGHAVKAWLGPVWDKHGAAIAAAGGSPNSGLGAVLAAIDSLPNADEIKSE IAALERPSMYMVDSDKGITNLHVPSDVIIDASMPAVIRAGGKGWDETGAKGDTNCVIPDRCYSTVYDETINFFKANGALD VTTAGSVANVGLMAQKAEEYGSHPTTFEAPADGEIRVILANGETLHSHEVEAGDIWRACTVKKAPIENWIQLALDRQRLT GSEAIFWLDANRAHDAELIKYVKPALDAAGVADKFLIMAPREATRQSLETITAGKDSIAITGNVLRDYLTDLFPILELGT SAKMLSIVKLMNGGGLFETGAGGSAPKHVQQLVEENHLRWDSMGEFCALGESLKFLADVKGNEKAGVLGAAAEVATQGIL DNNKSPERKVGQPDNRDSHYWFARYWAEALAAQGDDAELAAHFKPIAEALASNEAAILSELAAAQGGAADIGGYYHPSVE KKAAVMRPSATLNGIIG
Specific function: Unknown
COG id: COG2838
COG function: function code C; Monomeric isocitrate dehydrogenase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the monomeric-type IDH family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001804 - InterPro: IPR004436 [H]
Pfam domain/function: PF03971 IDH [H]
EC number: =1.1.1.42 [H]
Molecular weight: Translated: 78301; Mature: 78170
Theoretical pI: Translated: 4.66; Mature: 4.66
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAENSTPDILYTIVDEAPELASASFLPIIRKFADAAGVSVGTKDISLAARIIATFPENLT CCCCCCCCEEEEEECCCCHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHH EEQRQSDDLAALGELVKTPDANVIKLPNISASVPQLVAAIEELQAQGYKLPDYPYEPATD HHHHCCCHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC AEKEIRARYDTIKGSAVNPVLREGNSDRRSAKAVKNYAQNNPHSMGAWSGDSKTKVSSMP HHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCC GNDFYANEKSATISAEQAGDAKIEFVAKDGSVTVLKDGWPLAEGTVADATFMSAKALAAF CCCCCCCCCCCEEECCCCCCCEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH LSGAIEDTKADGTMFSLHMKATMMKVSDPIIFGHAVKAWLGPVWDKHGAAIAAAGGSPNS HHHHHHCCCCCCCEEEEEHHHHHHHHCCCEEEHHHHHHHHCHHHCCCCCEEEECCCCCCC GLGAVLAAIDSLPNADEIKSEIAALERPSMYMVDSDKGITNLHVPSDVIIDASMPAVIRA CHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCEEEECCCCHHEEC GGKGWDETGAKGDTNCVIPDRCYSTVYDETINFFKANGALDVTTAGSVANVGLMAQKAEE CCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHHHHH YGSHPTTFEAPADGEIRVILANGETLHSHEVEAGDIWRACTVKKAPIENWIQLALDRQRL HCCCCCEECCCCCCCEEEEEECCCEECCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHC TGSEAIFWLDANRAHDAELIKYVKPALDAAGVADKFLIMAPREATRQSLETITAGKDSIA CCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCEE ITGNVLRDYLTDLFPILELGTSAKMLSIVKLMNGGGLFETGAGGSAPKHVQQLVEENHLR EEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHCCCC WDSMGEFCALGESLKFLADVKGNEKAGVLGAAAEVATQGILDNNKSPERKVGQPDNRDSH CCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCC YWFARYWAEALAAQGDDAELAAHFKPIAEALASNEAAILSELAAAQGGAADIGGYYHPSV HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCC EKKAAVMRPSATLNGIIG HHHHHHCCCCCCCCCCCC >Mature Secondary Structure AENSTPDILYTIVDEAPELASASFLPIIRKFADAAGVSVGTKDISLAARIIATFPENLT CCCCCCCEEEEEECCCCHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHH EEQRQSDDLAALGELVKTPDANVIKLPNISASVPQLVAAIEELQAQGYKLPDYPYEPATD HHHHCCCHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC AEKEIRARYDTIKGSAVNPVLREGNSDRRSAKAVKNYAQNNPHSMGAWSGDSKTKVSSMP HHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCC GNDFYANEKSATISAEQAGDAKIEFVAKDGSVTVLKDGWPLAEGTVADATFMSAKALAAF CCCCCCCCCCCEEECCCCCCCEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH LSGAIEDTKADGTMFSLHMKATMMKVSDPIIFGHAVKAWLGPVWDKHGAAIAAAGGSPNS HHHHHHCCCCCCCEEEEEHHHHHHHHCCCEEEHHHHHHHHCHHHCCCCCEEEECCCCCCC GLGAVLAAIDSLPNADEIKSEIAALERPSMYMVDSDKGITNLHVPSDVIIDASMPAVIRA CHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCEEEECCCCHHEEC GGKGWDETGAKGDTNCVIPDRCYSTVYDETINFFKANGALDVTTAGSVANVGLMAQKAEE CCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHHHHH YGSHPTTFEAPADGEIRVILANGETLHSHEVEAGDIWRACTVKKAPIENWIQLALDRQRL HCCCCCEECCCCCCCEEEEEECCCEECCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHC TGSEAIFWLDANRAHDAELIKYVKPALDAAGVADKFLIMAPREATRQSLETITAGKDSIA CCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCEE ITGNVLRDYLTDLFPILELGTSAKMLSIVKLMNGGGLFETGAGGSAPKHVQQLVEENHLR EEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHCCCC WDSMGEFCALGESLKFLADVKGNEKAGVLGAAAEVATQGILDNNKSPERKVGQPDNRDSH CCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCC YWFARYWAEALAAQGDDAELAAHFKPIAEALASNEAAILSELAAAQGGAADIGGYYHPSV HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCC EKKAAVMRPSATLNGIIG HHHHHHCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12005040; 4149369; 12467571 [H]