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The map label for this gene is mcpA [H]

Identifier: 99080317

GI number: 99080317

Start: 495160

End: 496929

Strand: Reverse

Name: mcpA [H]

Synonym: TM1040_0476

Alternate gene names: 99080317

Gene position: 496929-495160 (Counterclockwise)

Preceding gene: 99080318

Following gene: 99080315

Centisome position: 15.52

GC content: 61.69

Gene sequence:

>1770_bases
ATGCCCGCCGCATTTTACGGACTATCCACTCGGATCTACGCCCTTGTAGCGCTTGCGCTCGTCGCGGCCGCAAGCTTGAC
TTTCTACACCCTGAACCATGCCTCTCAGACCGCCTATGATCTTCGGGCGGGAGAGTTGCGCCACATAACAGACATCGCCC
GCAGCCATCTGGACGCCCATAATGCCCGCGTCGAAGCCGGTGAAATGACCCAGGCCGAGGCGCAAGCCTCGGTGGCTCAA
ATTCTCAATGATCTGCGCTTTGGCGAAAACGGCTATGTCTATGCCTTTGACAGCGACATCGTCTATTCCGTCCACCCCTT
CCGCCCGCAATGGGTTGGAGGTGAGAGCCAGCGCGACCTGAAGGACGTGCATGGCAACCGGATCTTCGAAAACATCCTCG
GCAATCTGGATGCTGAGGGGCACTCGCTCTCGACGATCTATTTCGAGAACCCCGCGACCAAAGCCGTCGAACCCAAGCTC
ACATACGCACAATATTATGAACCCTGGGACTGGTACCTTGGGACCGGCGCCTACATGAACGACATTGAGGCCGACATCGC
GCAAATGCGGATGCAGGCCCTGATGGGGCTTGGTGTTGCCCTCGCCGTGTTGATCGGCGTATCGCTCTTGATTATCCGCA
GCATGCTGCCGCCTCTTGATGCGCTCAAGGCACGTATGGCCACCATGGCCGATGGCGACCTGGACGCGGATGTGCCGGGC
CTGTCGGATCGCAGCGAGATCGGCCAAATGGCGCATGCAGTGGCGAATTTCCGGGATGGGCTGCAAATGCAGGCAGCACT
GGAAGCAGAGGCGCACATCAAGGATGAGGAACGCCAGCGCGTCGTCGCCATCCTAAGCCAGCGTCTCGCGAAATTTGCCC
AGGGGGATCTCACCGTGCGCGTCGATGACGCCATGCCCGACGAGTTCCGGCAGGTGGCAGAAGACTTTAACGCAACGGTT
ACGCAGATCTCCGACCTGATGCGCACGCTGGTCGCCGGGGTGGAGCGGATTGAGAGCGAAAGCGAATCCCTCGACAGCTC
CTCGCGTGAGCTTGGCATGCGTACGGAAACCCAGGCAGCCTCTCTCGAAGAAACGTCCGCGGCCCTCACAGAGCTCTCGG
CTTCGGTGAAAAACTCTGCCGAAGAGAGCCGCGCAGCCTCCGAGCGGGTGCAGCAGGCCAGCGAACGGACCGAGCGCGGC
GCGCAGGTGGTCCGGCGCACCATTGAGGCCATGCAGGGGATCGAGGAAAGCTCCGACAAGATCTCGAGCATCACCTCTTT
GATCGACGATATCGCCTTTCAGACCAGCCTGCTGGCGCTCAACGCCGGGGTTGAGGCCGCACGCGCGGGCGAAGCCGGCC
GCGGGTTTGCGGTTGTGGCTGGCGAGGTGCGCGCTTTGGCCGGGAAATCCTCAGATGCGGCGCGCGAGATCGCAGAGTTG
ATCACAAACGCCAGCCGCGAGGTGGAGACCGGTGTGTCACTGGCGCGCGACTCTGGCACGGCTCTTGACGAGATCAACGC
GCATATCTCCGCCATCAACGAAACCGTCAGCGCCCTTGCTGAGGCGGCCCGGGAACAAGCCACAAGCCTCTCGGAGATCA
CCTCCGCCGCCGACCAGCTTGATCAGGTCACACAGCAGAACGCGGCAATGTTCGAGGAAACCTCTGCTGCAACCCAGCGC
CTGCGGGATGAGGCAAACGCCCTGGCTCAGAACGCCCGTCAGTTTCAGGTTGATGACGCGGATCCCGCTGCGCAACGCCG
GGCCTCATAA

Upstream 100 bases:

>100_bases
CCGGGTACCCGCAGGCGCATCAGATCGAGTCTGTAAAGCCGGTGTTAGGTTTTTTGTCAGAAAAAGGTCGCGAACCGAAA
ACACGCAAGGCCAAAAACCC

Downstream 100 bases:

>100_bases
GACAGCCCGCTCGCCCCTGACACCCAACCGTCCGCATCCCCGTGCGGGCGGTTTCCCTTTTCAAACGCGCCAGCTTCAAT
CAGAGCGACGCAAATTTCGC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 589; Mature: 588

Protein sequence:

>589_residues
MPAAFYGLSTRIYALVALALVAAASLTFYTLNHASQTAYDLRAGELRHITDIARSHLDAHNARVEAGEMTQAEAQASVAQ
ILNDLRFGENGYVYAFDSDIVYSVHPFRPQWVGGESQRDLKDVHGNRIFENILGNLDAEGHSLSTIYFENPATKAVEPKL
TYAQYYEPWDWYLGTGAYMNDIEADIAQMRMQALMGLGVALAVLIGVSLLIIRSMLPPLDALKARMATMADGDLDADVPG
LSDRSEIGQMAHAVANFRDGLQMQAALEAEAHIKDEERQRVVAILSQRLAKFAQGDLTVRVDDAMPDEFRQVAEDFNATV
TQISDLMRTLVAGVERIESESESLDSSSRELGMRTETQAASLEETSAALTELSASVKNSAEESRAASERVQQASERTERG
AQVVRRTIEAMQGIEESSDKISSITSLIDDIAFQTSLLALNAGVEAARAGEAGRGFAVVAGEVRALAGKSSDAAREIAEL
ITNASREVETGVSLARDSGTALDEINAHISAINETVSALAEAAREQATSLSEITSAADQLDQVTQQNAAMFEETSAATQR
LRDEANALAQNARQFQVDDADPAAQRRAS

Sequences:

>Translated_589_residues
MPAAFYGLSTRIYALVALALVAAASLTFYTLNHASQTAYDLRAGELRHITDIARSHLDAHNARVEAGEMTQAEAQASVAQ
ILNDLRFGENGYVYAFDSDIVYSVHPFRPQWVGGESQRDLKDVHGNRIFENILGNLDAEGHSLSTIYFENPATKAVEPKL
TYAQYYEPWDWYLGTGAYMNDIEADIAQMRMQALMGLGVALAVLIGVSLLIIRSMLPPLDALKARMATMADGDLDADVPG
LSDRSEIGQMAHAVANFRDGLQMQAALEAEAHIKDEERQRVVAILSQRLAKFAQGDLTVRVDDAMPDEFRQVAEDFNATV
TQISDLMRTLVAGVERIESESESLDSSSRELGMRTETQAASLEETSAALTELSASVKNSAEESRAASERVQQASERTERG
AQVVRRTIEAMQGIEESSDKISSITSLIDDIAFQTSLLALNAGVEAARAGEAGRGFAVVAGEVRALAGKSSDAAREIAEL
ITNASREVETGVSLARDSGTALDEINAHISAINETVSALAEAAREQATSLSEITSAADQLDQVTQQNAAMFEETSAATQR
LRDEANALAQNARQFQVDDADPAAQRRAS
>Mature_588_residues
PAAFYGLSTRIYALVALALVAAASLTFYTLNHASQTAYDLRAGELRHITDIARSHLDAHNARVEAGEMTQAEAQASVAQI
LNDLRFGENGYVYAFDSDIVYSVHPFRPQWVGGESQRDLKDVHGNRIFENILGNLDAEGHSLSTIYFENPATKAVEPKLT
YAQYYEPWDWYLGTGAYMNDIEADIAQMRMQALMGLGVALAVLIGVSLLIIRSMLPPLDALKARMATMADGDLDADVPGL
SDRSEIGQMAHAVANFRDGLQMQAALEAEAHIKDEERQRVVAILSQRLAKFAQGDLTVRVDDAMPDEFRQVAEDFNATVT
QISDLMRTLVAGVERIESESESLDSSSRELGMRTETQAASLEETSAALTELSASVKNSAEESRAASERVQQASERTERGA
QVVRRTIEAMQGIEESSDKISSITSLIDDIAFQTSLLALNAGVEAARAGEAGRGFAVVAGEVRALAGKSSDAAREIAELI
TNASREVETGVSLARDSGTALDEINAHISAINETVSALAEAAREQATSLSEITSAADQLDQVTQQNAAMFEETSAATQRL
RDEANALAQNARQFQVDDADPAAQRRAS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=304, Percent_Identity=36.8421052631579, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI2367378, Length=259, Percent_Identity=42.8571428571429, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1788195, Length=235, Percent_Identity=42.1276595744681, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1788194, Length=236, Percent_Identity=42.3728813559322, Blast_Score=173, Evalue=4e-44,
Organism=Escherichia coli, GI1789453, Length=253, Percent_Identity=36.3636363636364, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 63639; Mature: 63508

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAAFYGLSTRIYALVALALVAAASLTFYTLNHASQTAYDLRAGELRHITDIARSHLDAH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHCCHHHHHHHHHHHHHHHH
NARVEAGEMTQAEAQASVAQILNDLRFGENGYVYAFDSDIVYSVHPFRPQWVGGESQRDL
HCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCCCCCCCCHHHH
KDVHGNRIFENILGNLDAEGHSLSTIYFENPATKAVEPKLTYAQYYEPWDWYLGTGAYMN
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHCCCHHHEECCCCHHH
DIEADIAQMRMQALMGLGVALAVLIGVSLLIIRSMLPPLDALKARMATMADGDLDADVPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCC
LSDRSEIGQMAHAVANFRDGLQMQAALEAEAHIKDEERQRVVAILSQRLAKFAQGDLTVR
CCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEE
VDDAMPDEFRQVAEDFNATVTQISDLMRTLVAGVERIESESESLDSSSRELGMRTETQAA
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHH
SLEETSAALTELSASVKNSAEESRAASERVQQASERTERGAQVVRRTIEAMQGIEESSDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ISSITSLIDDIAFQTSLLALNAGVEAARAGEAGRGFAVVAGEVRALAGKSSDAAREIAEL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEHHHHHHHCCCCCHHHHHHHHH
ITNASREVETGVSLARDSGTALDEINAHISAINETVSALAEAAREQATSLSEITSAADQL
HHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQVTQQNAAMFEETSAATQRLRDEANALAQNARQFQVDDADPAAQRRAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHCCCC
>Mature Secondary Structure 
PAAFYGLSTRIYALVALALVAAASLTFYTLNHASQTAYDLRAGELRHITDIARSHLDAH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHCCHHHHHHHHHHHHHHHH
NARVEAGEMTQAEAQASVAQILNDLRFGENGYVYAFDSDIVYSVHPFRPQWVGGESQRDL
HCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCCCCCCCCHHHH
KDVHGNRIFENILGNLDAEGHSLSTIYFENPATKAVEPKLTYAQYYEPWDWYLGTGAYMN
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHCCCHHHEECCCCHHH
DIEADIAQMRMQALMGLGVALAVLIGVSLLIIRSMLPPLDALKARMATMADGDLDADVPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCC
LSDRSEIGQMAHAVANFRDGLQMQAALEAEAHIKDEERQRVVAILSQRLAKFAQGDLTVR
CCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEE
VDDAMPDEFRQVAEDFNATVTQISDLMRTLVAGVERIESESESLDSSSRELGMRTETQAA
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHH
SLEETSAALTELSASVKNSAEESRAASERVQQASERTERGAQVVRRTIEAMQGIEESSDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ISSITSLIDDIAFQTSLLALNAGVEAARAGEAGRGFAVVAGEVRALAGKSSDAAREIAEL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEHHHHHHHCCCCCHHHHHHHHH
ITNASREVETGVSLARDSGTALDEINAHISAINETVSALAEAAREQATSLSEITSAADQL
HHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQVTQQNAAMFEETSAATQRLRDEANALAQNARQFQVDDADPAAQRRAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]