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The map label for this gene is moeZ [H]

Identifier: 99080303

GI number: 99080303

Start: 480351

End: 481427

Strand: Direct

Name: moeZ [H]

Synonym: TM1040_0462

Alternate gene names: 99080303

Gene position: 480351-481427 (Clockwise)

Preceding gene: 99080302

Following gene: 99080304

Centisome position: 15.01

GC content: 61.84

Gene sequence:

>1077_bases
ATGATTTTGGTACTGGGGCTTGCGGGGCTGATCTGGTGGGGCGGGCGGCTCTTTGGGGCATCGCAGTCGATGCGCTGGGC
GTTGCTTGGTCTTTTGTTCCTGGCGGTTCTCAGCATCCAGCTGACCTTGCCCGAAGGCAATCCATTGCGTGCCGCCACTG
GGGGATCTGCGAGCCTGTGGCTCCTGATTGCCGGGACAGGGGCCTTGGTTGCGCTCTATGGCCGCGTGTTGAAGCGGCTG
CGCAACCGTGCGGATGCGCGCGAGGACAGTGCTGATGCGCCTGAGGCGGCTGCTCCGTTTCGGGACTCGGAACTGGACCG
CTATGCCCGCCACATCGTCCTGCGCGAGGTCGGAGGCGCTGGGCAAAAGCGCCTGAAAGACGCCAGAGTTCTGGTGATCG
GAGCGGGTGGCCTGGGGGCTCCCGCGCTGCAGTATCTGGCCGCTGCGGGCGTCGGCACCATCGGCGTTATTGACGATGAT
CGCGTCGAGAACGCCAATCTGCAACGACAGGTTATCCATCGTGACGCCGATATTGGCATGCCCAAGGTCTTCTCGGCTCA
GGCCGCGATGGAGGCGCAAAACCCTTTTGTGACCGTCCGTCCCTATCATCGTCGCCTCAGCGAGGATATCGCATCGGAAC
TCTTTGCGGAATATGACCTGATCCTCGACGGGACTGACAATTTCGACACTCGCTATCTGGCCAATGCGGCGGCGGTTGCG
CAGAGGAAACCCCTGATTTCCGGCGCCTTGTCGCAGTGGGAAGGCCAGATCTCCGTTTTTGATCCCGCCTCGGGCGGCCC
GTGTTACCAGTGTATTTTTCCCGAAAGCCCCGCCGCTGGCCTTGCGCCCAGCTGTGCAGAGGCGGGTGTAATTGGACCTT
TGCCCGGCGTTTTGGGCGCGATGATGGCTGTGGAGGCCGTGAAACAGATCACAGGCGCAGGAGAAGTCTTGCGCGCGCAG
ATGTTGATCTACGATGGTCTCTATGGTGAAACCCGCCGGATTGCGTTGAAAGCGCGCGCCGATTGTCCGATTTGCGGACC
CAATGCAGGCACCCCGGCCCCGACAGGAGAAAACTGA

Upstream 100 bases:

>100_bases
CAGTTCTGCGGGCGACCTTGAACGAGGTCGAGACATTCTCAAACAGCACGGAGCGTGGTGCGGGCGGCTTCGGCTCGACC
GGCTCGGGGGCGACCGGCGC

Downstream 100 bases:

>100_bases
ATATGACCCGCACTTTTGCCCTGACTGCCCTTGCAACGGCTGTCTTTGCCACCGGCGCCCTGGCTGCCGATCTGCCGGAT
CTTGAAGGGCGCGAGGTCGT

Product: UBA/THIF-type NAD/FAD binding fold

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MILVLGLAGLIWWGGRLFGASQSMRWALLGLLFLAVLSIQLTLPEGNPLRAATGGSASLWLLIAGTGALVALYGRVLKRL
RNRADAREDSADAPEAAAPFRDSELDRYARHIVLREVGGAGQKRLKDARVLVIGAGGLGAPALQYLAAAGVGTIGVIDDD
RVENANLQRQVIHRDADIGMPKVFSAQAAMEAQNPFVTVRPYHRRLSEDIASELFAEYDLILDGTDNFDTRYLANAAAVA
QRKPLISGALSQWEGQISVFDPASGGPCYQCIFPESPAAGLAPSCAEAGVIGPLPGVLGAMMAVEAVKQITGAGEVLRAQ
MLIYDGLYGETRRIALKARADCPICGPNAGTPAPTGEN

Sequences:

>Translated_358_residues
MILVLGLAGLIWWGGRLFGASQSMRWALLGLLFLAVLSIQLTLPEGNPLRAATGGSASLWLLIAGTGALVALYGRVLKRL
RNRADAREDSADAPEAAAPFRDSELDRYARHIVLREVGGAGQKRLKDARVLVIGAGGLGAPALQYLAAAGVGTIGVIDDD
RVENANLQRQVIHRDADIGMPKVFSAQAAMEAQNPFVTVRPYHRRLSEDIASELFAEYDLILDGTDNFDTRYLANAAAVA
QRKPLISGALSQWEGQISVFDPASGGPCYQCIFPESPAAGLAPSCAEAGVIGPLPGVLGAMMAVEAVKQITGAGEVLRAQ
MLIYDGLYGETRRIALKARADCPICGPNAGTPAPTGEN
>Mature_358_residues
MILVLGLAGLIWWGGRLFGASQSMRWALLGLLFLAVLSIQLTLPEGNPLRAATGGSASLWLLIAGTGALVALYGRVLKRL
RNRADAREDSADAPEAAAPFRDSELDRYARHIVLREVGGAGQKRLKDARVLVIGAGGLGAPALQYLAAAGVGTIGVIDDD
RVENANLQRQVIHRDADIGMPKVFSAQAAMEAQNPFVTVRPYHRRLSEDIASELFAEYDLILDGTDNFDTRYLANAAAVA
QRKPLISGALSQWEGQISVFDPASGGPCYQCIFPESPAAGLAPSCAEAGVIGPLPGVLGAMMAVEAVKQITGAGEVLRAQ
MLIYDGLYGETRRIALKARADCPICGPNAGTPAPTGEN

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=254, Percent_Identity=44.8818897637795, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI38045944, Length=181, Percent_Identity=29.8342541436464, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI38045942, Length=181, Percent_Identity=29.8342541436464, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4885649, Length=159, Percent_Identity=29.559748427673, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI150417996, Length=227, Percent_Identity=27.7533039647577, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI23510338, Length=225, Percent_Identity=27.1111111111111, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI23510340, Length=225, Percent_Identity=27.1111111111111, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI38045948, Length=156, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787048, Length=252, Percent_Identity=43.2539682539683, Blast_Score=207, Evalue=7e-55,
Organism=Escherichia coli, GI87082356, Length=253, Percent_Identity=37.9446640316205, Blast_Score=159, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17540406, Length=249, Percent_Identity=40.1606425702811, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI193203301, Length=152, Percent_Identity=30.2631578947368, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71984476, Length=177, Percent_Identity=30.5084745762712, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321903, Length=275, Percent_Identity=41.0909090909091, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6320598, Length=173, Percent_Identity=28.9017341040462, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322639, Length=167, Percent_Identity=29.3413173652695, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582879, Length=261, Percent_Identity=40.6130268199234, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI28573937, Length=224, Percent_Identity=29.0178571428571, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24660640, Length=151, Percent_Identity=30.4635761589404, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI20129973, Length=176, Percent_Identity=28.9772727272727, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 37769; Mature: 37769

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVLGLAGLIWWGGRLFGASQSMRWALLGLLFLAVLSIQLTLPEGNPLRAATGGSASLW
CEEEEEHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCEEEECCCCCEEE
LLIAGTGALVALYGRVLKRLRNRADAREDSADAPEAAAPFRDSELDRYARHIVLREVGGA
EEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
GQKRLKDARVLVIGAGGLGAPALQYLAAAGVGTIGVIDDDRVENANLQRQVIHRDADIGM
CHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCC
PKVFSAQAAMEAQNPFVTVRPYHRRLSEDIASELFAEYDLILDGTDNFDTRYLANAAAVA
CCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHH
QRKPLISGALSQWEGQISVFDPASGGPCYQCIFPESPAAGLAPSCAEAGVIGPLPGVLGA
HHCCHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCHHHCCCCCCHHHHHHH
MMAVEAVKQITGAGEVLRAQMLIYDGLYGETRRIALKARADCPICGPNAGTPAPTGEN
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MILVLGLAGLIWWGGRLFGASQSMRWALLGLLFLAVLSIQLTLPEGNPLRAATGGSASLW
CEEEEEHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCEEEECCCCCEEE
LLIAGTGALVALYGRVLKRLRNRADAREDSADAPEAAAPFRDSELDRYARHIVLREVGGA
EEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
GQKRLKDARVLVIGAGGLGAPALQYLAAAGVGTIGVIDDDRVENANLQRQVIHRDADIGM
CHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCC
PKVFSAQAAMEAQNPFVTVRPYHRRLSEDIASELFAEYDLILDGTDNFDTRYLANAAAVA
CCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHH
QRKPLISGALSQWEGQISVFDPASGGPCYQCIFPESPAAGLAPSCAEAGVIGPLPGVLGA
HHCCHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCHHHCCCCCCHHHHHHH
MMAVEAVKQITGAGEVLRAQMLIYDGLYGETRRIALKARADCPICGPNAGTPAPTGEN
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]