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The map label for this gene is comM [H]

Identifier: 99080293

GI number: 99080293

Start: 469699

End: 471201

Strand: Reverse

Name: comM [H]

Synonym: TM1040_0452

Alternate gene names: 99080293

Gene position: 471201-469699 (Counterclockwise)

Preceding gene: 99080294

Following gene: 99080288

Centisome position: 14.72

GC content: 64.47

Gene sequence:

>1503_bases
ATGATTTCACGTGCACAAACTGTTGCATTTCAAGGTGTTGAAGCCTGTCCGGTTGAGGTTCAATGTGCCGTCGCCCCAGG
GCTTCCGGCGTTTTCCATCGTGGGCCTTCCCGATAAGGCCGTCAGCGAAGCCCGCGACCGGGTGCGATCAGCCTTGGCGG
TCATGTCGATTGCCTTGCCCGCGAAACGGATCACCATCAACCTATCGCCAGCCGATCTCCCCAAAGAGGGCAGCCATTTT
GATCTTCCAATCGCAGTCGCATTGCTGACGGCCCTGGAAATCTTGCCACCGGAAGCTGCCGAGGAGACCCTCTCGCTTGG
TGAGCTGTCGCTGGATGGAACCTTGGTCGCAATCACCGGCGCCTTGCCCGCCGCCTTAACAGCCGCCGAACAACAGCGCA
CGCTGCTCTGCCCCAAAAGCTCCAGCGCCGAGGCAGCCTGGGTCGAAGCTGCAACCGTAATTGGTGCGGCGTCGCTCTCA
GACGTAATCCGCCATTTCACCGGACAAGGCGTCCTTGCACCCGCCCAGCCGGGCGAGGTGTTGGATGACCCGCTCGAGAA
GGATCTCGCCGATGTCAAAGGCCAGGAGGGTCCGCGCCGTGCGCTCGAGATTGCCGCTGCTGGACGCCATCACCTGCTGA
TGAGCGGCCCACCAGGCGCGGGGAAATCCATGCTTGCGGCGCGGCTGCCCTCGATCCTACCACCGCTTTCGCCCGGGGAG
GCGCTGGAGACGTCGATGATCCAATCCATCTGTGGCCTGATCAAAGCCGGGGGCGTCAGCCGCGCGCGCCCGTTTCGCGC
GCCTCATCACACCGCCTCCATGGCGGCCATCGTGGGGGGCGGGCGTCGTGCGCACCCCGGAGAGATCAGCCTCGCGCATA
ATGGAGTGCTGTTTCTCGACGAGTTGCCGGAATTTGCGCGCGCCGTCCTTGAGACCCTTCGGCAACCGCTGGAAACGGGT
GACGTGATGGTGGCCCGCGCCAATGCTCATGTGCGCTATCCAAGCCGCTTCATGCTTGTGGCAGCGGCCAACCCCTGCCG
TTGTGGCTATCTGACCGACCCTGCCCGCGCCTGCCCCCGCGCGCCGGGGTGCGGTGCGGATTACATGGGCCGGATTTCAG
GGCCGTTGATGGACCGGTTTGACCTGCGCATCGAGGTCGAGCCCGTCGCCTTTGCCGATCTCGAACGCAGTCGCCCCGGC
GAGAGCTCTGCCAGTGTTGCGAGCCGCGTTGCGCAAGCGCGCGCGCTTCAGGGGGAACGCTATGCCGCCTGCGACGGCAC
CCATACCAATGCGGATGCAGAGGGTGAGATGCTGGAAAAAGTCGCAGAGCTGGGCACCGACAGTCGCGCGCTCCTGCTCC
AAGCTGCCGAGCAGTTTGGCCTGAGTGCGCGCGGCTATCACCGGGTCTTGCGCGTTGCCCGCACCATTGCGGATCTGGAT
GCCGAAGCGCAGATCGCCCGCGATCATGTAGCCGAGGCACTGTCCTACCGCCTGCCCAGTTAG

Upstream 100 bases:

>100_bases
CGATTTCGCGCTGGACTTACGCCATCCTTAACCAATCGGTAACCACGTTTTTAAATGCTGCTCCCTATGGGCCTGTTTTG
AGGCACCGCAGGGGGCGGCC

Downstream 100 bases:

>100_bases
CGCGCAGTAAACGCCGCGCGTGCAAAATCGGCAATCTCCCTCAGCGACTTACGGGCCTCGGGGACCCAGCCCTGAAACAG
ATGCCAGACATGTGGTGCGC

Product: Mg chelatase-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MISRAQTVAFQGVEACPVEVQCAVAPGLPAFSIVGLPDKAVSEARDRVRSALAVMSIALPAKRITINLSPADLPKEGSHF
DLPIAVALLTALEILPPEAAEETLSLGELSLDGTLVAITGALPAALTAAEQQRTLLCPKSSSAEAAWVEAATVIGAASLS
DVIRHFTGQGVLAPAQPGEVLDDPLEKDLADVKGQEGPRRALEIAAAGRHHLLMSGPPGAGKSMLAARLPSILPPLSPGE
ALETSMIQSICGLIKAGGVSRARPFRAPHHTASMAAIVGGGRRAHPGEISLAHNGVLFLDELPEFARAVLETLRQPLETG
DVMVARANAHVRYPSRFMLVAAANPCRCGYLTDPARACPRAPGCGADYMGRISGPLMDRFDLRIEVEPVAFADLERSRPG
ESSASVASRVAQARALQGERYAACDGTHTNADAEGEMLEKVAELGTDSRALLLQAAEQFGLSARGYHRVLRVARTIADLD
AEAQIARDHVAEALSYRLPS

Sequences:

>Translated_500_residues
MISRAQTVAFQGVEACPVEVQCAVAPGLPAFSIVGLPDKAVSEARDRVRSALAVMSIALPAKRITINLSPADLPKEGSHF
DLPIAVALLTALEILPPEAAEETLSLGELSLDGTLVAITGALPAALTAAEQQRTLLCPKSSSAEAAWVEAATVIGAASLS
DVIRHFTGQGVLAPAQPGEVLDDPLEKDLADVKGQEGPRRALEIAAAGRHHLLMSGPPGAGKSMLAARLPSILPPLSPGE
ALETSMIQSICGLIKAGGVSRARPFRAPHHTASMAAIVGGGRRAHPGEISLAHNGVLFLDELPEFARAVLETLRQPLETG
DVMVARANAHVRYPSRFMLVAAANPCRCGYLTDPARACPRAPGCGADYMGRISGPLMDRFDLRIEVEPVAFADLERSRPG
ESSASVASRVAQARALQGERYAACDGTHTNADAEGEMLEKVAELGTDSRALLLQAAEQFGLSARGYHRVLRVARTIADLD
AEAQIARDHVAEALSYRLPS
>Mature_500_residues
MISRAQTVAFQGVEACPVEVQCAVAPGLPAFSIVGLPDKAVSEARDRVRSALAVMSIALPAKRITINLSPADLPKEGSHF
DLPIAVALLTALEILPPEAAEETLSLGELSLDGTLVAITGALPAALTAAEQQRTLLCPKSSSAEAAWVEAATVIGAASLS
DVIRHFTGQGVLAPAQPGEVLDDPLEKDLADVKGQEGPRRALEIAAAGRHHLLMSGPPGAGKSMLAARLPSILPPLSPGE
ALETSMIQSICGLIKAGGVSRARPFRAPHHTASMAAIVGGGRRAHPGEISLAHNGVLFLDELPEFARAVLETLRQPLETG
DVMVARANAHVRYPSRFMLVAAANPCRCGYLTDPARACPRAPGCGADYMGRISGPLMDRFDLRIEVEPVAFADLERSRPG
ESSASVASRVAQARALQGERYAACDGTHTNADAEGEMLEKVAELGTDSRALLLQAAEQFGLSARGYHRVLRVARTIADLD
AEAQIARDHVAEALSYRLPS

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=497, Percent_Identity=43.8631790744467, Blast_Score=384, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 52466; Mature: 52466

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISRAQTVAFQGVEACPVEVQCAVAPGLPAFSIVGLPDKAVSEARDRVRSALAVMSIALP
CCCCHHHHHHCCCCCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
AKRITINLSPADLPKEGSHFDLPIAVALLTALEILPPEAAEETLSLGELSLDGTLVAITG
CEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCEECCCEEEEEEC
ALPAALTAAEQQRTLLCPKSSSAEAAWVEAATVIGAASLSDVIRHFTGQGVLAPAQPGEV
CHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHH
LDDPLEKDLADVKGQEGPRRALEIAAAGRHHLLMSGPPGAGKSMLAARLPSILPPLSPGE
HHCHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCH
ALETSMIQSICGLIKAGGVSRARPFRAPHHTASMAAIVGGGRRAHPGEISLAHNGVLFLD
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEECCCEEEHH
ELPEFARAVLETLRQPLETGDVMVARANAHVRYPSRFMLVAAANPCRCGYLTDPARACPR
HHHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCCEEEEEEECCCCCCCCCCCHHHHCCC
APGCGADYMGRISGPLMDRFDLRIEVEPVAFADLERSRPGESSASVASRVAQARALQGER
CCCCCHHHHHHCCCCCCCCEEEEEEECCEEEHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
YAACDGTHTNADAEGEMLEKVAELGTDSRALLLQAAEQFGLSARGYHRVLRVARTIADLD
EEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
AEAQIARDHVAEALSYRLPS
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MISRAQTVAFQGVEACPVEVQCAVAPGLPAFSIVGLPDKAVSEARDRVRSALAVMSIALP
CCCCHHHHHHCCCCCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
AKRITINLSPADLPKEGSHFDLPIAVALLTALEILPPEAAEETLSLGELSLDGTLVAITG
CEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCEECCCEEEEEEC
ALPAALTAAEQQRTLLCPKSSSAEAAWVEAATVIGAASLSDVIRHFTGQGVLAPAQPGEV
CHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHH
LDDPLEKDLADVKGQEGPRRALEIAAAGRHHLLMSGPPGAGKSMLAARLPSILPPLSPGE
HHCHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCH
ALETSMIQSICGLIKAGGVSRARPFRAPHHTASMAAIVGGGRRAHPGEISLAHNGVLFLD
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEECCCEEEHH
ELPEFARAVLETLRQPLETGDVMVARANAHVRYPSRFMLVAAANPCRCGYLTDPARACPR
HHHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCCEEEEEEECCCCCCCCCCCHHHHCCC
APGCGADYMGRISGPLMDRFDLRIEVEPVAFADLERSRPGESSASVASRVAQARALQGER
CCCCCHHHHHHCCCCCCCCEEEEEEECCEEEHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
YAACDGTHTNADAEGEMLEKVAELGTDSRALLLQAAEQFGLSARGYHRVLRVARTIADLD
EEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
AEAQIARDHVAEALSYRLPS
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]