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The map label for this gene is gapB [H]

Identifier: 99080258

GI number: 99080258

Start: 427011

End: 428015

Strand: Reverse

Name: gapB [H]

Synonym: TM1040_0417

Alternate gene names: 99080258

Gene position: 428015-427011 (Counterclockwise)

Preceding gene: 99080261

Following gene: 99080255

Centisome position: 13.37

GC content: 61.79

Gene sequence:

>1005_bases
ATGACCCTTAAAATCGCGATCAATGGATTTGGCCGGATCGGCCGCAACGTGCTGCGTGCACTTTTGGAGAACGACACCAC
CGACGTTGAGGTGGTGGCGATCAACGATCTCGCCCCCCCGGCAACCCAAGTCCACCTGCTGAAGTTCGACAGCGTTCACG
GCCGCCTCGACGCAGAGGTTACAGTCGAGGGCGATACCATGAAAGTGGGCCGCCATGAGATCCGCCTGACGGCCATCCGC
AACCCAGAAGAGCTGCCCTGGTCCGATGTCGATATCGCCTATGAATGCACTGGCCTCTTCACTACCCGCGACAAAGCAGC
CGCGCATCTGAAAAACGGCTCCAAACGCGTGCTGATTTCCGCGCCGGGGACCGAAGTTGACCGCACCGTGGTCTTTGGCG
TCAATGATCGCGACCTCACCGCAGAGGACATCGTGGTGTCCAACGCCTCCTGCACCACCAACTGCCTTGCCCCGGTGGCC
AAGGTTCTGGACGACGCCTTTGGGATCAAGACCGGTTATATGACCACGATCCACGCCTACACAGGCGACCAGCCGACCCA
TGACACCACCCACAAGGATCTCTACCGCGCCCGCGCGGCAGCGCTCTCGATGATCCCAACATCTACCGGCGCGGCGCGCG
CGATCTCCCTGGTGCTGCCACACCTCAAGGGCCGCCTTGAAGGTTCCGCCATTCGCGTCCCGACACCAAATGTCTCGGTG
GTGGACCTGACGTTCCAGCCCGAGCGTGTCGCTTCGGTCGAAGAGATCAACGCCGCGATCGCGGCCGCCGCAAAAGAGGG
CCCGCTTCAGGGCATTCTCGGCTATGAAGAGGCTCCACTGGTGTCCATCGACTTCAACCACGACAAGCGGTCGTCGATCT
TCGCCGCCCCACAAACCGCCGTGACCTCCGAGGGCCTGGTGCGCGTGGTGAGCTGGTATGACAACGAGTGGGGCTTTTCG
AACCGCATGATCGACACCGGCCGCGCCATGGGCAAATTCCTCTGA

Upstream 100 bases:

>100_bases
GGGCTTGATCGGCGCCTTCGTTAGCGATAACGATAGCCGCGAGTGATAGCGGTACCAGTGGTGGTGCCGTGCCCGGAAAC
CCAACCGGAGTTATTGGCAA

Downstream 100 bases:

>100_bases
CGCAATACCGCTGCGCGACATACCTCACGCCATGTTACAAAGGGCCGCAGCAAATGCCGCGGCCCTTCTTCATGTCATCG
TTTTCTTCTAACCAAAAATA

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTLKIAINGFGRIGRNVLRALLENDTTDVEVVAINDLAPPATQVHLLKFDSVHGRLDAEVTVEGDTMKVGRHEIRLTAIR
NPEELPWSDVDIAYECTGLFTTRDKAAAHLKNGSKRVLISAPGTEVDRTVVFGVNDRDLTAEDIVVSNASCTTNCLAPVA
KVLDDAFGIKTGYMTTIHAYTGDQPTHDTTHKDLYRARAAALSMIPTSTGAARAISLVLPHLKGRLEGSAIRVPTPNVSV
VDLTFQPERVASVEEINAAIAAAAKEGPLQGILGYEEAPLVSIDFNHDKRSSIFAAPQTAVTSEGLVRVVSWYDNEWGFS
NRMIDTGRAMGKFL

Sequences:

>Translated_334_residues
MTLKIAINGFGRIGRNVLRALLENDTTDVEVVAINDLAPPATQVHLLKFDSVHGRLDAEVTVEGDTMKVGRHEIRLTAIR
NPEELPWSDVDIAYECTGLFTTRDKAAAHLKNGSKRVLISAPGTEVDRTVVFGVNDRDLTAEDIVVSNASCTTNCLAPVA
KVLDDAFGIKTGYMTTIHAYTGDQPTHDTTHKDLYRARAAALSMIPTSTGAARAISLVLPHLKGRLEGSAIRVPTPNVSV
VDLTFQPERVASVEEINAAIAAAAKEGPLQGILGYEEAPLVSIDFNHDKRSSIFAAPQTAVTSEGLVRVVSWYDNEWGFS
NRMIDTGRAMGKFL
>Mature_333_residues
TLKIAINGFGRIGRNVLRALLENDTTDVEVVAINDLAPPATQVHLLKFDSVHGRLDAEVTVEGDTMKVGRHEIRLTAIRN
PEELPWSDVDIAYECTGLFTTRDKAAAHLKNGSKRVLISAPGTEVDRTVVFGVNDRDLTAEDIVVSNASCTTNCLAPVAK
VLDDAFGIKTGYMTTIHAYTGDQPTHDTTHKDLYRARAAALSMIPTSTGAARAISLVLPHLKGRLEGSAIRVPTPNVSVV
DLTFQPERVASVEEINAAIAAAAKEGPLQGILGYEEAPLVSIDFNHDKRSSIFAAPQTAVTSEGLVRVVSWYDNEWGFSN
RMIDTGRAMGKFL

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=333, Percent_Identity=45.945945945946, Blast_Score=279, Evalue=2e-75,
Organism=Homo sapiens, GI7669492, Length=327, Percent_Identity=45.8715596330275, Blast_Score=279, Evalue=3e-75,
Organism=Escherichia coli, GI1789295, Length=335, Percent_Identity=48.0597014925373, Blast_Score=314, Evalue=5e-87,
Organism=Escherichia coli, GI1788079, Length=328, Percent_Identity=49.0853658536585, Blast_Score=304, Evalue=5e-84,
Organism=Caenorhabditis elegans, GI17534677, Length=333, Percent_Identity=49.8498498498498, Blast_Score=296, Evalue=8e-81,
Organism=Caenorhabditis elegans, GI17534679, Length=333, Percent_Identity=49.2492492492492, Blast_Score=294, Evalue=3e-80,
Organism=Caenorhabditis elegans, GI32566163, Length=331, Percent_Identity=49.8489425981873, Blast_Score=293, Evalue=8e-80,
Organism=Caenorhabditis elegans, GI17568413, Length=331, Percent_Identity=49.8489425981873, Blast_Score=293, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6322468, Length=327, Percent_Identity=47.0948012232416, Blast_Score=282, Evalue=4e-77,
Organism=Saccharomyces cerevisiae, GI6322409, Length=327, Percent_Identity=46.7889908256881, Blast_Score=281, Evalue=1e-76,
Organism=Saccharomyces cerevisiae, GI6321631, Length=329, Percent_Identity=47.7203647416413, Blast_Score=279, Evalue=4e-76,
Organism=Drosophila melanogaster, GI17933600, Length=331, Percent_Identity=48.9425981873112, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI18110149, Length=331, Percent_Identity=48.9425981873112, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI85725000, Length=331, Percent_Identity=48.3383685800604, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI22023983, Length=331, Percent_Identity=48.3383685800604, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=42.7692307692308, Blast_Score=258, Evalue=5e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36117; Mature: 35986

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKIAINGFGRIGRNVLRALLENDTTDVEVVAINDLAPPATQVHLLKFDSVHGRLDAEV
CEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCEEE
TVEGDTMKVGRHEIRLTAIRNPEELPWSDVDIAYECTGLFTTRDKAAAHLKNGSKRVLIS
EECCCEEECCCEEEEEEEECCCCCCCCCCCCEEEEEEEEEEECHHHHHHHCCCCCEEEEE
APGTEVDRTVVFGVNDRDLTAEDIVVSNASCTTNCLAPVAKVLDDAFGIKTGYMTTIHAY
CCCCCCCCEEEEECCCCCCCHHHEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEE
TGDQPTHDTTHKDLYRARAAALSMIPTSTGAARAISLVLPHLKGRLEGSAIRVPTPNVSV
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCEE
VDLTFQPERVASVEEINAAIAAAAKEGPLQGILGYEEAPLVSIDFNHDKRSSIFAAPQTA
EEEEECCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCEEEEECCCCCCCCEEECCCHH
VTSEGLVRVVSWYDNEWGFSNRMIDTGRAMGKFL
CCCCCCEEEEEEECCCCCCCCCEECCCHHHHCCC
>Mature Secondary Structure 
TLKIAINGFGRIGRNVLRALLENDTTDVEVVAINDLAPPATQVHLLKFDSVHGRLDAEV
EEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCEEE
TVEGDTMKVGRHEIRLTAIRNPEELPWSDVDIAYECTGLFTTRDKAAAHLKNGSKRVLIS
EECCCEEECCCEEEEEEEECCCCCCCCCCCCEEEEEEEEEEECHHHHHHHCCCCCEEEEE
APGTEVDRTVVFGVNDRDLTAEDIVVSNASCTTNCLAPVAKVLDDAFGIKTGYMTTIHAY
CCCCCCCCEEEEECCCCCCCHHHEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEE
TGDQPTHDTTHKDLYRARAAALSMIPTSTGAARAISLVLPHLKGRLEGSAIRVPTPNVSV
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCEE
VDLTFQPERVASVEEINAAIAAAAKEGPLQGILGYEEAPLVSIDFNHDKRSSIFAAPQTA
EEEEECCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCEEEEECCCCCCCCEEECCCHH
VTSEGLVRVVSWYDNEWGFSNRMIDTGRAMGKFL
CCCCCCEEEEEEECCCCCCCCCEECCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1939098 [H]