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The map label for this gene is yfcG [H]

Identifier: 99080050

GI number: 99080050

Start: 226220

End: 226921

Strand: Direct

Name: yfcG [H]

Synonym: TM1040_0209

Alternate gene names: 99080050

Gene position: 226220-226921 (Clockwise)

Preceding gene: 99080049

Following gene: 99080051

Centisome position: 7.07

GC content: 57.41

Gene sequence:

>702_bases
ATGTCGCAACCTGATATAATCCTCTACACCGCCAACACGATGAACGGGTGGAAGCCGCTAATCTTCTTGCACGAAGCGGA
GATCGATTACGAATTGGTCAATGTCGACTTTTCCAAAAAAGAGCAGCATGCCCCCGATTATGTGAAGATGAATCCAAACG
GAAAGATCCCGACGATCTGGGACCGCTCCGAAGGGCGCGCGATCTTTGAAAGCGGTGCAATCCTCTGGCATCTGGCCGAG
AAATACGGGCGCTTTCTGTCTTCTGACCCGGTGGAGCGGTCTGAAACCTTGCAGTGGCTTTTCTTTCAGGTCGGCCATAT
CGGTCCGATCATGGGGCAGGCGATGTTCTTTCAGCGCATCGCCAAACCCAATGGCGACGAGGTGCCCTATGCCATCAAAC
GCTACGTGGATGAGAGCCGACGCCTGCTGGAGGTGCTCGACACAAGGCTTGCGGGGCGCGACTGGCTGGTTGGCACAGAG
ATGTCGATCGCGGACATCGCAACCTACCCTTGGGCGCGCAGTCATTTTTGGGCCACGGTAGAGGTCGAAGGACTACCGCA
CTTGCAGGCATGGTTCGACCGGCTTGATGCGATGCCAAAGGTACAAGAGGCCCTGCAACTGCCCGAGCCGCGTCCTTCGG
CGTTTGGCAAGGGCGACATCGCGGCGGCGGCCTCCGCCAATGCTGCCCGTTTCAAGGAGTAA

Upstream 100 bases:

>100_bases
CCAAGCTTTGCTGCCTTTGACGTCATGAAAAATCCCGAGATTGACGCCGACCTGATCCGGTTCGACGCACATCTCGACAG
CCTATTTGCGGAGGCCGAAG

Downstream 100 bases:

>100_bases
AGCGATGACCCTTCGTGTGGATATTGTGTCGGACGTGGTCTGTCCCTGGTGTGTGATCGGGTATCTCCAGCTGGCCAAGG
CTGCGGCAGAAACCGGCACA

Product: glutathione S-transferase-like

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MSQPDIILYTANTMNGWKPLIFLHEAEIDYELVNVDFSKKEQHAPDYVKMNPNGKIPTIWDRSEGRAIFESGAILWHLAE
KYGRFLSSDPVERSETLQWLFFQVGHIGPIMGQAMFFQRIAKPNGDEVPYAIKRYVDESRRLLEVLDTRLAGRDWLVGTE
MSIADIATYPWARSHFWATVEVEGLPHLQAWFDRLDAMPKVQEALQLPEPRPSAFGKGDIAAAASANAARFKE

Sequences:

>Translated_233_residues
MSQPDIILYTANTMNGWKPLIFLHEAEIDYELVNVDFSKKEQHAPDYVKMNPNGKIPTIWDRSEGRAIFESGAILWHLAE
KYGRFLSSDPVERSETLQWLFFQVGHIGPIMGQAMFFQRIAKPNGDEVPYAIKRYVDESRRLLEVLDTRLAGRDWLVGTE
MSIADIATYPWARSHFWATVEVEGLPHLQAWFDRLDAMPKVQEALQLPEPRPSAFGKGDIAAAASANAARFKE
>Mature_232_residues
SQPDIILYTANTMNGWKPLIFLHEAEIDYELVNVDFSKKEQHAPDYVKMNPNGKIPTIWDRSEGRAIFESGAILWHLAEK
YGRFLSSDPVERSETLQWLFFQVGHIGPIMGQAMFFQRIAKPNGDEVPYAIKRYVDESRRLLEVLDTRLAGRDWLVGTEM
SIADIATYPWARSHFWATVEVEGLPHLQAWFDRLDAMPKVQEALQLPEPRPSAFGKGDIAAAASANAARFKE

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=205, Percent_Identity=44.8780487804878, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI87082195, Length=214, Percent_Identity=34.5794392523364, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI87081789, Length=174, Percent_Identity=29.3103448275862, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1787923, Length=189, Percent_Identity=28.042328042328, Blast_Score=61, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6324100, Length=233, Percent_Identity=30.0429184549356, Blast_Score=103, Evalue=2e-23,
Organism=Drosophila melanogaster, GI20130115, Length=208, Percent_Identity=30.2884615384615, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24654983, Length=187, Percent_Identity=31.5508021390374, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19922532, Length=185, Percent_Identity=28.1081081081081, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17933730, Length=179, Percent_Identity=27.9329608938547, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17864592, Length=186, Percent_Identity=29.5698924731183, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19922526, Length=225, Percent_Identity=28.4444444444444, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571670, Length=160, Percent_Identity=28.125, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI85725204, Length=171, Percent_Identity=29.2397660818713, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17737923, Length=171, Percent_Identity=29.2397660818713, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17864598, Length=157, Percent_Identity=31.2101910828025, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24654965, Length=192, Percent_Identity=27.0833333333333, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 26564; Mature: 26433

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPDIILYTANTMNGWKPLIFLHEAEIDYELVNVDFSKKEQHAPDYVKMNPNGKIPTIW
CCCCCEEEEECCCCCCCCEEEEEEECCCCEEEEECCCCCHHCCCCCEEEECCCCCCCEEE
DRSEGRAIFESGAILWHLAEKYGRFLSSDPVERSETLQWLFFQVGHIGPIMGQAMFFQRI
ECCCCCEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AKPNGDEVPYAIKRYVDESRRLLEVLDTRLAGRDWLVGTEMSIADIATYPWARSHFWATV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHCCCCCCCCEEEEE
EVEGLPHLQAWFDRLDAMPKVQEALQLPEPRPSAFGKGDIAAAASANAARFKE
EECCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHCCCCHHHCCC
>Mature Secondary Structure 
SQPDIILYTANTMNGWKPLIFLHEAEIDYELVNVDFSKKEQHAPDYVKMNPNGKIPTIW
CCCCEEEEECCCCCCCCEEEEEEECCCCEEEEECCCCCHHCCCCCEEEECCCCCCCEEE
DRSEGRAIFESGAILWHLAEKYGRFLSSDPVERSETLQWLFFQVGHIGPIMGQAMFFQRI
ECCCCCEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AKPNGDEVPYAIKRYVDESRRLLEVLDTRLAGRDWLVGTEMSIADIATYPWARSHFWATV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHCCCCCCCCEEEEE
EVEGLPHLQAWFDRLDAMPKVQEALQLPEPRPSAFGKGDIAAAASANAARFKE
EECCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]