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The map label for this gene is mdaB [H]

Identifier: 99080049

GI number: 99080049

Start: 225625

End: 226233

Strand: Direct

Name: mdaB [H]

Synonym: TM1040_0208

Alternate gene names: 99080049

Gene position: 225625-226233 (Clockwise)

Preceding gene: 99080047

Following gene: 99080050

Centisome position: 7.05

GC content: 60.43

Gene sequence:

>609_bases
ATGAGCAAGATACTGATCCTGAACGGGGCGCAGCCCTATCCCTTTGCGCCGGGCGGGCTCAATGCGACCCTGGCAGAGCG
GGCGCGCGCACGCCTCCTTGCGCAAGGCCACGAGGTACGCCTGACCACCGTGGCCGAGGGCTATGACGTGGAGCAGGAGG
TCGCCAATCACCAGTGGGCCGATGCGATCATCCTGCAGTTCCCGGTAAATTGGATGGGGGTTCCGTGGTCGTTCAAGAAA
TACATGGATGAGGTCTATACTGCGGGCATGGACGGGCGGCTCTGCGCTGGCGATGGTCGCACGGCTGATGCACCCAAGGC
GAACTACGGCATGGGCGGCACACTCGGGGGCACGCGCTATATGATTTCGGCAACATTCAACGCCCCGGCAGAGGCGTTCG
ACACCCCCGATGAGCCGTTCTTTGAAGGCGCGTCTATGGATGACCTGCTTCGTCCGGTGCATCTCAACGCAAAGTTCTTT
GACATGGCGCCTCTGCCAAGCTTTGCTGCCTTTGACGTCATGAAAAATCCCGAGATTGACGCCGACCTGATCCGGTTCGA
CGCACATCTCGACAGCCTATTTGCGGAGGCCGAAGATGTCGCAACCTGA

Upstream 100 bases:

>100_bases
AAAAAGTATACTGGTTGAATATCGTTTCCACCATGCGCAATTTCGGTCCGAGCGGGACGCAAGTCAAGCGCCCCGGTTTA
CGCCAAGAAGGACGAGATTG

Downstream 100 bases:

>100_bases
TATAATCCTCTACACCGCCAACACGATGAACGGGTGGAAGCCGCTAATCTTCTTGCACGAAGCGGAGATCGATTACGAAT
TGGTCAATGTCGACTTTTCC

Product: NAD(P)H dehydrogenase (quinone)

Products: NADP; a reduced quinone; reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MSKILILNGAQPYPFAPGGLNATLAERARARLLAQGHEVRLTTVAEGYDVEQEVANHQWADAIILQFPVNWMGVPWSFKK
YMDEVYTAGMDGRLCAGDGRTADAPKANYGMGGTLGGTRYMISATFNAPAEAFDTPDEPFFEGASMDDLLRPVHLNAKFF
DMAPLPSFAAFDVMKNPEIDADLIRFDAHLDSLFAEAEDVAT

Sequences:

>Translated_202_residues
MSKILILNGAQPYPFAPGGLNATLAERARARLLAQGHEVRLTTVAEGYDVEQEVANHQWADAIILQFPVNWMGVPWSFKK
YMDEVYTAGMDGRLCAGDGRTADAPKANYGMGGTLGGTRYMISATFNAPAEAFDTPDEPFFEGASMDDLLRPVHLNAKFF
DMAPLPSFAAFDVMKNPEIDADLIRFDAHLDSLFAEAEDVAT
>Mature_201_residues
SKILILNGAQPYPFAPGGLNATLAERARARLLAQGHEVRLTTVAEGYDVEQEVANHQWADAIILQFPVNWMGVPWSFKKY
MDEVYTAGMDGRLCAGDGRTADAPKANYGMGGTLGGTRYMISATFNAPAEAFDTPDEPFFEGASMDDLLRPVHLNAKFFD
MAPLPSFAAFDVMKNPEIDADLIRFDAHLDSLFAEAEDVAT

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae HI_0648 and S.pombe SPAC5H10.05c [H]

Homologues:

Organism=Escherichia coli, GI1789406, Length=195, Percent_Identity=45.1282051282051, Blast_Score=169, Evalue=9e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: NA

Molecular weight: Translated: 22084; Mature: 21953

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS00148 ARGINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKILILNGAQPYPFAPGGLNATLAERARARLLAQGHEVRLTTVAEGYDVEQEVANHQWA
CCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHCCCCC
DAIILQFPVNWMGVPWSFKKYMDEVYTAGMDGRLCAGDGRTADAPKANYGMGGTLGGTRY
CEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEE
MISATFNAPAEAFDTPDEPFFEGASMDDLLRPVHLNAKFFDMAPLPSFAAFDVMKNPEID
EEEEECCCCHHHCCCCCCCCCCCCCHHHHHCCEECCCEEEECCCCCCHHHHHHCCCCCCC
ADLIRFDAHLDSLFAEAEDVAT
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKILILNGAQPYPFAPGGLNATLAERARARLLAQGHEVRLTTVAEGYDVEQEVANHQWA
CEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHCCCCC
DAIILQFPVNWMGVPWSFKKYMDEVYTAGMDGRLCAGDGRTADAPKANYGMGGTLGGTRY
CEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEE
MISATFNAPAEAFDTPDEPFFEGASMDDLLRPVHLNAKFFDMAPLPSFAAFDVMKNPEID
EEEEECCCCHHHCCCCCCCCCCCCCHHHHHCCEECCCEEEECCCCCCHHHHHHCCCCCCC
ADLIRFDAHLDSLFAEAEDVAT
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; a quinone; Acceptor; NADPH [C]

Specific reaction: NADPH + a quinone = NADP + a reduced quinone Acceptor + NADPH = reduced acceptor + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]