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The map label for this gene is vpr [H]

Identifier: 94986321

GI number: 94986321

Start: 2340452

End: 2343127

Strand: Reverse

Name: vpr [H]

Synonym: Dgeo_2222

Alternate gene names: 94986321

Gene position: 2343127-2340452 (Counterclockwise)

Preceding gene: 94986322

Following gene: 94986318

Centisome position: 94.97

GC content: 63.53

Gene sequence:

>2676_bases
GTGAACAAGACTGCCAAGACGCTTGCCCTACTCAGCCTGTCCCTGGTTTTGGGTGCCTGCGGTCAGAGCGGCGCACCCAC
TGCCACCGCACCCCAGGGCGCCCTGCTGCCCGCATCGGCCCACGCCAACAACCTGACCCCTAGCCGGTGGTTTGTGGAAT
TGGAGGGGGACCCCACCGCCCTAGGAACCCAGAGCATCAGCAGTCAGCAGGCCAGCTTCCGCGCGCAGGCTCAGAGCCTT
GGCCTTCACTACCAGGAAGTGCGCAGCTACAACACGCTGTTTAACGGCTTTAGTGTCATCGCCACCGGCAGTGAGATCAA
CCGTATCTCCCGGATGCCGGGTGTGCTGGGCGTGTACCCGGTCCACAGGGTTGACCTGCCCAAGCCTGACCTGCAGGCCG
CCCTGCAGCCGCAGATGTTCTACGCCAAGGGCATGACCGGCGCGGATATCGCCCAAAACGAACTGGGCCTGACCGGCAAG
GGCGTGAAGGTCGGCGTGATCGACACGGGCATCGACGTGGATCACCCGGCCTTCCAGGGCCGCATCGTGGCTGGATACGA
CTTCGTGGGGGATGATTACGGCAAGGATGGCAAGTATGTTCCGGTGCCTGACGACAACCCCGATGACTGTAATGGACACG
GCACCCACGTCGCTGGGATTGTCGGCGGCAATGACCCTGCCACCGGCTTCAAGGGCGTCGCTCCTGAGGTGAGCTTTGGT
GCCTACCGGATCTTCGGCTGTGAGGGCAGCTCCTACGACGACGTGATCCTGGCGGCCATGGAACGTGCCCAGAAGGACGG
AATGCAGGTCATCAACATGAGCCTGGGGAGCGCCTTCGAGAACTGGAAGGAAACGCCCCTCGCCAAGGCTGCCGACCGCC
TGGTGAAAAAAGGCGTGGTCGTCGTCGCGTCCGGCGGCAACAGCGGTGCGAACGGACAGTACAGCATGGGTGGCCCGACC
ATGGGCGACAATGTGATCTCGGTCGCCTCGGTGGATAACGTCAAGGTTGACCTGGATAGCTTTACCCTCTCAGACGGCAG
CAAGGTTGGTTACTACGTAGCGACCGGGGCACCTGAACCGACCAAGGGTCTGACCCTGCCCATCACCAAGAAGCCGGGCA
GCACGACGACGACACCCAACGACGGATGCACCGCCAGTGGAGGCTTTGCTGCGGGCAGTCTGACCGGCAAGGCCGTGCTG
ATTCGCCGTGGCGGCTGCACCTTCTATGAGAAGGCCAGCAATGCCCAGAAGGCCGGAGCTGCCGCCGTCATCCTGTACAA
CAACGCTGCCGGCTACATCAGCCCTACGGTGTCGGGCGAACCACCCATCACCATTCCGGTGGTGGCCATCAGCGATACCG
ACGGTGCGAAGATCAACAGTCTGCTCGGCTCGGGCGTGAGCGTGACTTTCGACGGCGGCAAGATTGCCGTGGCCAACCCC
ACCGGCAACACCATCAGCAGCTTCTCGTCCATCGGCATGTCCGCCGAGCTGGAACTCAAGCCGGACATCGCCGCGCCCGG
CGGAAACATCTACAGCAGCTATCCCCTCAGTGCCGATCCCAGTGGCTACGCCGTCCTGAGCGGCACCAGCATGGCCTCGC
CGCACGTGGCTGGGGCGGCGGCCCTGATGCTTCAGGCGTATCCCAACACCCAGGCCAAGGACATGCGCACCCTGCTGATG
AACACCGCCTCGCTGCGCTGGTTCTACAACAACAAACCGCTGGAAGGGATCCCCGACTATGTGCAGCGCCAAGGCGCGGG
CATGGTGGACATCGTGAACGCCTACGACAACACGGTGCGTGCCACGCCCAGCAAGCTCAGCCTGGGTGAGAGCGAGACCT
TCGCCACCCGCAGCAAGGTGGTCGTCCTGAAGAACACCGGCGCCAAGCGCGAGGTCTACCAGGTGACCCACGTGCCCGCC
CTGACGATCAGCGGCACCACCAACGCGCCCAAGCCCAGCGGGGCAGTCGCCAGCATGACCATCAACGGTACCGATGTGGA
CAACGGCAGCCTGGAAGTCGTGGTGCCGCCCTTTGGTGAGGTGGAACTGAACGTGACCATCACCCCACCCGGCGGCGCTG
CCGACAATTCGCAGTACGGCGGGTACATCTCGCTCAAGAGCGCGACCGGTGCCAATCTGGTGGTGCCCTACAGCGGCTTT
AAGGGCGACTACCAGAGCCTGAAGTCCTTTGGGGACGTCACCCTTGACGGGAAGACCCGCCTCAACTTCCCCATCCTGGT
GGACGACGCGGCGGACGACTTCTACCAGGAAGGCCAGACCCTCAATGCCGTGCCCGACTACACCTTTAAGAAGGTGGAGG
TCACCTACAGCGACGGCACAAAGGCGACCGTCCTGGACGCCCCGTATCTGCTGGCGAACCTCGCGCACCAGATCCGCACG
CTGACCTTCGAGCTGCTCGATGCCAACGGGAATGTCGTGGATACGCTCGGCAAGTACAACTACCTCAGCCGAGACTGCAC
CGACGACTACACCAAGACCAGCTCCACCTGCACGGCCTTCGAGGCTTTCGATTGGGACGGCAAGCTCAGCAACGGTCAGG
ACGCCCCGAATGGCCTCTACCAGCTGCGCCTGCGTGCCCTCAAGCCGCTGGGCGACGAGAGCAACCCCGCTCATACCGAG
GTCTACACCAGCCAGCGCTTCGCCGTCGTGCGCTGA

Upstream 100 bases:

>100_bases
CAGCTTTGACATCTACGACGATGAGCAGCTGACCGACGACCGGGCGACCAACACCTACCAGATTCTGCTGACGCGCCGCT
AACTACGAAGGAGTGAGTCC

Downstream 100 bases:

>100_bases
TCTGCACCCAGGTAAACCGGAAAAGGAGGCACACGCCTTTTCCGGTTTCTTGTTGCTTGGTGTTGCTTATCCCAGCGCCG
CCAGCGCGTTCTCCCAGCGC

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 891; Mature: 891

Protein sequence:

>891_residues
MNKTAKTLALLSLSLVLGACGQSGAPTATAPQGALLPASAHANNLTPSRWFVELEGDPTALGTQSISSQQASFRAQAQSL
GLHYQEVRSYNTLFNGFSVIATGSEINRISRMPGVLGVYPVHRVDLPKPDLQAALQPQMFYAKGMTGADIAQNELGLTGK
GVKVGVIDTGIDVDHPAFQGRIVAGYDFVGDDYGKDGKYVPVPDDNPDDCNGHGTHVAGIVGGNDPATGFKGVAPEVSFG
AYRIFGCEGSSYDDVILAAMERAQKDGMQVINMSLGSAFENWKETPLAKAADRLVKKGVVVVASGGNSGANGQYSMGGPT
MGDNVISVASVDNVKVDLDSFTLSDGSKVGYYVATGAPEPTKGLTLPITKKPGSTTTTPNDGCTASGGFAAGSLTGKAVL
IRRGGCTFYEKASNAQKAGAAAVILYNNAAGYISPTVSGEPPITIPVVAISDTDGAKINSLLGSGVSVTFDGGKIAVANP
TGNTISSFSSIGMSAELELKPDIAAPGGNIYSSYPLSADPSGYAVLSGTSMASPHVAGAAALMLQAYPNTQAKDMRTLLM
NTASLRWFYNNKPLEGIPDYVQRQGAGMVDIVNAYDNTVRATPSKLSLGESETFATRSKVVVLKNTGAKREVYQVTHVPA
LTISGTTNAPKPSGAVASMTINGTDVDNGSLEVVVPPFGEVELNVTITPPGGAADNSQYGGYISLKSATGANLVVPYSGF
KGDYQSLKSFGDVTLDGKTRLNFPILVDDAADDFYQEGQTLNAVPDYTFKKVEVTYSDGTKATVLDAPYLLANLAHQIRT
LTFELLDANGNVVDTLGKYNYLSRDCTDDYTKTSSTCTAFEAFDWDGKLSNGQDAPNGLYQLRLRALKPLGDESNPAHTE
VYTSQRFAVVR

Sequences:

>Translated_891_residues
MNKTAKTLALLSLSLVLGACGQSGAPTATAPQGALLPASAHANNLTPSRWFVELEGDPTALGTQSISSQQASFRAQAQSL
GLHYQEVRSYNTLFNGFSVIATGSEINRISRMPGVLGVYPVHRVDLPKPDLQAALQPQMFYAKGMTGADIAQNELGLTGK
GVKVGVIDTGIDVDHPAFQGRIVAGYDFVGDDYGKDGKYVPVPDDNPDDCNGHGTHVAGIVGGNDPATGFKGVAPEVSFG
AYRIFGCEGSSYDDVILAAMERAQKDGMQVINMSLGSAFENWKETPLAKAADRLVKKGVVVVASGGNSGANGQYSMGGPT
MGDNVISVASVDNVKVDLDSFTLSDGSKVGYYVATGAPEPTKGLTLPITKKPGSTTTTPNDGCTASGGFAAGSLTGKAVL
IRRGGCTFYEKASNAQKAGAAAVILYNNAAGYISPTVSGEPPITIPVVAISDTDGAKINSLLGSGVSVTFDGGKIAVANP
TGNTISSFSSIGMSAELELKPDIAAPGGNIYSSYPLSADPSGYAVLSGTSMASPHVAGAAALMLQAYPNTQAKDMRTLLM
NTASLRWFYNNKPLEGIPDYVQRQGAGMVDIVNAYDNTVRATPSKLSLGESETFATRSKVVVLKNTGAKREVYQVTHVPA
LTISGTTNAPKPSGAVASMTINGTDVDNGSLEVVVPPFGEVELNVTITPPGGAADNSQYGGYISLKSATGANLVVPYSGF
KGDYQSLKSFGDVTLDGKTRLNFPILVDDAADDFYQEGQTLNAVPDYTFKKVEVTYSDGTKATVLDAPYLLANLAHQIRT
LTFELLDANGNVVDTLGKYNYLSRDCTDDYTKTSSTCTAFEAFDWDGKLSNGQDAPNGLYQLRLRALKPLGDESNPAHTE
VYTSQRFAVVR
>Mature_891_residues
MNKTAKTLALLSLSLVLGACGQSGAPTATAPQGALLPASAHANNLTPSRWFVELEGDPTALGTQSISSQQASFRAQAQSL
GLHYQEVRSYNTLFNGFSVIATGSEINRISRMPGVLGVYPVHRVDLPKPDLQAALQPQMFYAKGMTGADIAQNELGLTGK
GVKVGVIDTGIDVDHPAFQGRIVAGYDFVGDDYGKDGKYVPVPDDNPDDCNGHGTHVAGIVGGNDPATGFKGVAPEVSFG
AYRIFGCEGSSYDDVILAAMERAQKDGMQVINMSLGSAFENWKETPLAKAADRLVKKGVVVVASGGNSGANGQYSMGGPT
MGDNVISVASVDNVKVDLDSFTLSDGSKVGYYVATGAPEPTKGLTLPITKKPGSTTTTPNDGCTASGGFAAGSLTGKAVL
IRRGGCTFYEKASNAQKAGAAAVILYNNAAGYISPTVSGEPPITIPVVAISDTDGAKINSLLGSGVSVTFDGGKIAVANP
TGNTISSFSSIGMSAELELKPDIAAPGGNIYSSYPLSADPSGYAVLSGTSMASPHVAGAAALMLQAYPNTQAKDMRTLLM
NTASLRWFYNNKPLEGIPDYVQRQGAGMVDIVNAYDNTVRATPSKLSLGESETFATRSKVVVLKNTGAKREVYQVTHVPA
LTISGTTNAPKPSGAVASMTINGTDVDNGSLEVVVPPFGEVELNVTITPPGGAADNSQYGGYISLKSATGANLVVPYSGF
KGDYQSLKSFGDVTLDGKTRLNFPILVDDAADDFYQEGQTLNAVPDYTFKKVEVTYSDGTKATVLDAPYLLANLAHQIRT
LTFELLDANGNVVDTLGKYNYLSRDCTDDYTKTSSTCTAFEAFDWDGKLSNGQDAPNGLYQLRLRALKPLGDESNPAHTE
VYTSQRFAVVR

Specific function: Not required for growth or sporulation [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319893, Length=189, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR010259
- InterPro:   IPR003137 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF02225 PA; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 93180; Mature: 93180

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTAKTLALLSLSLVLGACGQSGAPTATAPQGALLPASAHANNLTPSRWFVELEGDPTA
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEEECCCCCC
LGTQSISSQQASFRAQAQSLGLHYQEVRSYNTLFNGFSVIATGSEINRISRMPGVLGVYP
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEECHHHHHHHHCCCCEEECC
VHRVDLPKPDLQAALQPQMFYAKGMTGADIAQNELGLTGKGVKVGVIDTGIDVDHPAFQG
EEECCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCC
RIVAGYDFVGDDYGKDGKYVPVPDDNPDDCNGHGTHVAGIVGGNDPATGFKGVAPEVSFG
EEEEEEEECCCCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
AYRIFGCEGSSYDDVILAAMERAQKDGMQVINMSLGSAFENWKETPLAKAADRLVKKGVV
EEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHCCEE
VVASGGNSGANGQYSMGGPTMGDNVISVASVDNVKVDLDSFTLSDGSKVGYYVATGAPEP
EEECCCCCCCCCEEECCCCCCCCCEEEEEECCCEEEEECEEEECCCCEEEEEEEECCCCC
TKGLTLPITKKPGSTTTTPNDGCTASGGFAAGSLTGKAVLIRRGGCTFYEKASNAQKAGA
CCCEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCHHHHCCCCCCCCC
AAVILYNNAAGYISPTVSGEPPITIPVVAISDTDGAKINSLLGSGVSVTFDGGKIAVANP
EEEEEEECCCCEECCCCCCCCCEEEEEEEEECCCCCHHHHHHCCCCEEEECCCEEEEECC
TGNTISSFSSIGMSAELELKPDIAAPGGNIYSSYPLSADPSGYAVLSGTSMASPHVAGAA
CCCHHHHHHHCCCEEEEEECCCCCCCCCCCEECCCCCCCCCCEEEEECCCCCCCCHHHHE
ALMLQAYPNTQAKDMRTLLMNTASLRWFYNNKPLEGIPDYVQRQGAGMVDIVNAYDNTVR
EEEEEECCCCCHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHCCCCEEEEEECCCCCEE
ATPSKLSLGESETFATRSKVVVLKNTGAKREVYQVTHVPALTISGTTNAPKPSGAVASMT
CCCCCCCCCCCCCEECCCEEEEEECCCCCCEEEEEECCCEEEEECCCCCCCCCCCEEEEE
INGTDVDNGSLEVVVPPFGEVELNVTITPPGGAADNSQYGGYISLKSATGANLVVPYSGF
ECCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCEEEEECCCCCEEEEECCCC
KGDYQSLKSFGDVTLDGKTRLNFPILVDDAADDFYQEGQTLNAVPDYTFKKVEVTYSDGT
CCCHHHHHHCCCEEECCCEEECCCEEEECCCHHHHHCCCEEECCCCCCEEEEEEEECCCC
KATVLDAPYLLANLAHQIRTLTFELLDANGNVVDTLGKYNYLSRDCTDDYTKTSSTCTAF
EEEEECCHHHHHHHHHHHHEEEEEEECCCCCEEECCCCCCCCCCCCCCCHHCCCCCEEEE
EAFDWDGKLSNGQDAPNGLYQLRLRALKPLGDESNPAHTEVYTSQRFAVVR
EEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEEEC
>Mature Secondary Structure
MNKTAKTLALLSLSLVLGACGQSGAPTATAPQGALLPASAHANNLTPSRWFVELEGDPTA
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEEECCCCCC
LGTQSISSQQASFRAQAQSLGLHYQEVRSYNTLFNGFSVIATGSEINRISRMPGVLGVYP
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEECHHHHHHHHCCCCEEECC
VHRVDLPKPDLQAALQPQMFYAKGMTGADIAQNELGLTGKGVKVGVIDTGIDVDHPAFQG
EEECCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCC
RIVAGYDFVGDDYGKDGKYVPVPDDNPDDCNGHGTHVAGIVGGNDPATGFKGVAPEVSFG
EEEEEEEECCCCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
AYRIFGCEGSSYDDVILAAMERAQKDGMQVINMSLGSAFENWKETPLAKAADRLVKKGVV
EEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHCCEE
VVASGGNSGANGQYSMGGPTMGDNVISVASVDNVKVDLDSFTLSDGSKVGYYVATGAPEP
EEECCCCCCCCCEEECCCCCCCCCEEEEEECCCEEEEECEEEECCCCEEEEEEEECCCCC
TKGLTLPITKKPGSTTTTPNDGCTASGGFAAGSLTGKAVLIRRGGCTFYEKASNAQKAGA
CCCEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCHHHHCCCCCCCCC
AAVILYNNAAGYISPTVSGEPPITIPVVAISDTDGAKINSLLGSGVSVTFDGGKIAVANP
EEEEEEECCCCEECCCCCCCCCEEEEEEEEECCCCCHHHHHHCCCCEEEECCCEEEEECC
TGNTISSFSSIGMSAELELKPDIAAPGGNIYSSYPLSADPSGYAVLSGTSMASPHVAGAA
CCCHHHHHHHCCCEEEEEECCCCCCCCCCCEECCCCCCCCCCEEEEECCCCCCCCHHHHE
ALMLQAYPNTQAKDMRTLLMNTASLRWFYNNKPLEGIPDYVQRQGAGMVDIVNAYDNTVR
EEEEEECCCCCHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHCCCCEEEEEECCCCCEE
ATPSKLSLGESETFATRSKVVVLKNTGAKREVYQVTHVPALTISGTTNAPKPSGAVASMT
CCCCCCCCCCCCCEECCCEEEEEECCCCCCEEEEEECCCEEEEECCCCCCCCCCCEEEEE
INGTDVDNGSLEVVVPPFGEVELNVTITPPGGAADNSQYGGYISLKSATGANLVVPYSGF
ECCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCEEEEECCCCCEEEEECCCC
KGDYQSLKSFGDVTLDGKTRLNFPILVDDAADDFYQEGQTLNAVPDYTFKKVEVTYSDGT
CCCHHHHHHCCCEEECCCEEECCCEEEECCCHHHHHCCCEEECCCCCCEEEEEEEECCCC
KATVLDAPYLLANLAHQIRTLTFELLDANGNVVDTLGKYNYLSRDCTDDYTKTSSTCTAF
EEEEECCHHHHHHHHHHHHEEEEEEECCCCCEEECCCCCCCCCCCCCCCHHCCCCCEEEE
EAFDWDGKLSNGQDAPNGLYQLRLRALKPLGDESNPAHTEVYTSQRFAVVR
EEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1938892; 7934828; 9384377; 10658653 [H]