| Definition | Deinococcus geothermalis DSM 11300, complete genome. |
|---|---|
| Accession | NC_008025 |
| Length | 2,467,205 |
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The map label for this gene is ppiB [H]
Identifier: 94986318
GI number: 94986318
Start: 2338322
End: 2339086
Strand: Reverse
Name: ppiB [H]
Synonym: Dgeo_2219
Alternate gene names: 94986318
Gene position: 2339086-2338322 (Counterclockwise)
Preceding gene: 94986321
Following gene: 94986314
Centisome position: 94.81
GC content: 65.23
Gene sequence:
>765_bases ATGAAACAGGCCGCCCTGCTCCTGACCGTTCTGCTCGCCCTGACCGCCTGCCAGAAAAAGGACGCCGCAGCGACCAGCCA AACGGAGACTGCCACGACCGACACCAAGACCGATACCGGCACCGACGCGGCCAAGACCGCCGAGGTCACGGCGCCCGGCC CCATTCCGGCGGGCTACACCCTGGTGCCGTTCCTGACCGACCAGCCGGTGCGCGCCTTCAAGGCTGAACCCGCTATGACG CTGCAGGCGGGCAAGGACTACTACGCCCTGATCGACACCAACCGGGGCCAGATTCTCGCCGACCTCTACGAGCAGGAGAC GCCCGTCACGGTCAACAACTTCGTGACGCTGGCCCGCAACCACTTCTACGACGGCCTGCGCTTTCACCGGGTCATCGACG GCTTCATGGCCCAGACTGGTGATCCCAAGAGCGCGGACGAGGCGAAGAAGGCCGAGTGGGGCACCGGCGGCCCCGGCTAC CAGTTCGCCGACGAGTTTCGCAGCAAGCTCACCTTTGACAGTCCCGGGATTCTGGCCATGGCCAATAGCGGCCCCGCCAC CAACGGCTCGCAGTTTTTCATCACCTTCGCCCCCACCGACTTTCTGAATGGCCGCCACACCATCTTCGGCAAGGTGATCA GCGGCGACGACGTGCTGGACAAACTCACCCGCACCAGCGACACCAGCAGTGGCTCGGAAACCCCAATCCCCGGCGCCGTC CCCGACAAGATCCTGACGGTGCGGATCCTGACCAAGGGGAGCTGA
Upstream 100 bases:
>100_bases CCACTGGCGGCCACGCCGTCTATCGTCACGATCACCCGCCCAGTGTAGAGGGTGGAAGGGAAAGGCGCGGTCCTCACCTG GGCCCGCTAGACTGCTCGCC
Downstream 100 bases:
>100_bases GGGGAAGCGGGCGCTTGATCCGCCTGCCTCAATCCTCGTCCGCGTAGTACTCGAAGCGGAAGCTGCCGATCTCGACGGTG TCGCCCTCACGGGCTCCGGC
Product: peptidylprolyl isomerase
Products: NA
Alternate protein names: PPIase; Rotamase [H]
Number of amino acids: Translated: 254; Mature: 254
Protein sequence:
>254_residues MKQAALLLTVLLALTACQKKDAAATSQTETATTDTKTDTGTDAAKTAEVTAPGPIPAGYTLVPFLTDQPVRAFKAEPAMT LQAGKDYYALIDTNRGQILADLYEQETPVTVNNFVTLARNHFYDGLRFHRVIDGFMAQTGDPKSADEAKKAEWGTGGPGY QFADEFRSKLTFDSPGILAMANSGPATNGSQFFITFAPTDFLNGRHTIFGKVISGDDVLDKLTRTSDTSSGSETPIPGAV PDKILTVRILTKGS
Sequences:
>Translated_254_residues MKQAALLLTVLLALTACQKKDAAATSQTETATTDTKTDTGTDAAKTAEVTAPGPIPAGYTLVPFLTDQPVRAFKAEPAMT LQAGKDYYALIDTNRGQILADLYEQETPVTVNNFVTLARNHFYDGLRFHRVIDGFMAQTGDPKSADEAKKAEWGTGGPGY QFADEFRSKLTFDSPGILAMANSGPATNGSQFFITFAPTDFLNGRHTIFGKVISGDDVLDKLTRTSDTSSGSETPIPGAV PDKILTVRILTKGS >Mature_254_residues MKQAALLLTVLLALTACQKKDAAATSQTETATTDTKTDTGTDAAKTAEVTAPGPIPAGYTLVPFLTDQPVRAFKAEPAMT LQAGKDYYALIDTNRGQILADLYEQETPVTVNNFVTLARNHFYDGLRFHRVIDGFMAQTGDPKSADEAKKAEWGTGGPGY QFADEFRSKLTFDSPGILAMANSGPATNGSQFFITFAPTDFLNGRHTIFGKVISGDDVLDKLTRTSDTSSGSETPIPGAV PDKILTVRILTKGS
Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]
COG id: COG0652
COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
Gene ontology:
Cell location: Periplasmic Protein [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PPIase cyclophilin-type domain [H]
Homologues:
Organism=Homo sapiens, GI24308049, Length=135, Percent_Identity=45.9259259259259, Blast_Score=129, Evalue=3e-30, Organism=Homo sapiens, GI7706339, Length=140, Percent_Identity=43.5714285714286, Blast_Score=127, Evalue=1e-29, Organism=Homo sapiens, GI22547215, Length=132, Percent_Identity=45.4545454545455, Blast_Score=117, Evalue=7e-27, Organism=Homo sapiens, GI22547212, Length=132, Percent_Identity=45.4545454545455, Blast_Score=117, Evalue=7e-27, Organism=Homo sapiens, GI7657473, Length=132, Percent_Identity=45.4545454545455, Blast_Score=117, Evalue=7e-27, Organism=Homo sapiens, GI19557636, Length=134, Percent_Identity=41.044776119403, Blast_Score=116, Evalue=2e-26, Organism=Homo sapiens, GI64276486, Length=164, Percent_Identity=40.2439024390244, Blast_Score=113, Evalue=2e-25, Organism=Homo sapiens, GI4758950, Length=164, Percent_Identity=40.2439024390244, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI4505991, Length=137, Percent_Identity=43.7956204379562, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI10863927, Length=135, Percent_Identity=41.4814814814815, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI5454154, Length=135, Percent_Identity=41.4814814814815, Blast_Score=95, Evalue=5e-20, Organism=Homo sapiens, GI5031987, Length=144, Percent_Identity=40.9722222222222, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI45439316, Length=144, Percent_Identity=39.5833333333333, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI303305009, Length=141, Percent_Identity=41.1347517730496, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI5174637, Length=133, Percent_Identity=42.1052631578947, Blast_Score=91, Evalue=7e-19, Organism=Homo sapiens, GI4826932, Length=135, Percent_Identity=40, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI310129267, Length=133, Percent_Identity=37.593984962406, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI310120620, Length=133, Percent_Identity=37.593984962406, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI169163387, Length=133, Percent_Identity=39.0977443609023, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI20911035, Length=140, Percent_Identity=32.8571428571429, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI310127646, Length=135, Percent_Identity=37.037037037037, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI310114371, Length=135, Percent_Identity=37.037037037037, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI310119221, Length=135, Percent_Identity=37.037037037037, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI169164185, Length=133, Percent_Identity=39.0977443609023, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI169163623, Length=133, Percent_Identity=39.0977443609023, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI310110104, Length=133, Percent_Identity=36.0902255639098, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI256017253, Length=123, Percent_Identity=43.0894308943089, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI221139811, Length=123, Percent_Identity=43.0894308943089, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI256017251, Length=123, Percent_Identity=43.0894308943089, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI178057341, Length=145, Percent_Identity=39.3103448275862, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI42560244, Length=141, Percent_Identity=35.4609929078014, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI209417936, Length=145, Percent_Identity=39.3103448275862, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI30102944, Length=145, Percent_Identity=39.3103448275862, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI219842199, Length=145, Percent_Identity=39.3103448275862, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI6631100, Length=146, Percent_Identity=39.041095890411, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI310132444, Length=135, Percent_Identity=37.037037037037, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI310113152, Length=135, Percent_Identity=37.037037037037, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI239751853, Length=131, Percent_Identity=35.8778625954198, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI113428306, Length=131, Percent_Identity=35.8778625954198, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI169214050, Length=131, Percent_Identity=35.8778625954198, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI14277126, Length=66, Percent_Identity=46.969696969697, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI150418007, Length=134, Percent_Identity=38.8059701492537, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI310114540, Length=126, Percent_Identity=37.3015873015873, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI310127745, Length=126, Percent_Identity=37.3015873015873, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI310119290, Length=126, Percent_Identity=37.3015873015873, Blast_Score=69, Evalue=4e-12, Organism=Escherichia coli, GI1789763, Length=187, Percent_Identity=33.1550802139037, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1786736, Length=156, Percent_Identity=32.6923076923077, Blast_Score=74, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17539496, Length=138, Percent_Identity=44.2028985507246, Blast_Score=125, Evalue=2e-29, Organism=Caenorhabditis elegans, GI17532641, Length=211, Percent_Identity=32.7014218009479, Blast_Score=122, Evalue=2e-28, Organism=Caenorhabditis elegans, GI17506311, Length=139, Percent_Identity=44.6043165467626, Blast_Score=121, Evalue=4e-28, Organism=Caenorhabditis elegans, GI71980594, Length=132, Percent_Identity=43.9393939393939, Blast_Score=113, Evalue=8e-26, Organism=Caenorhabditis elegans, GI71980590, Length=132, Percent_Identity=43.9393939393939, Blast_Score=113, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17552780, Length=136, Percent_Identity=45.5882352941176, Blast_Score=103, Evalue=9e-23, Organism=Caenorhabditis elegans, GI17506307, Length=137, Percent_Identity=44.5255474452555, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI71997782, Length=129, Percent_Identity=40.3100775193798, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17559074, Length=156, Percent_Identity=37.8205128205128, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17566266, Length=148, Percent_Identity=37.8378378378378, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17552782, Length=159, Percent_Identity=40.251572327044, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17551282, Length=136, Percent_Identity=41.1764705882353, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17551284, Length=136, Percent_Identity=41.1764705882353, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17539498, Length=135, Percent_Identity=40, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI32563659, Length=138, Percent_Identity=34.7826086956522, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17552784, Length=140, Percent_Identity=38.5714285714286, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17532643, Length=131, Percent_Identity=40.4580152671756, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17565860, Length=147, Percent_Identity=36.0544217687075, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI115533296, Length=131, Percent_Identity=35.1145038167939, Blast_Score=69, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6320359, Length=147, Percent_Identity=40.1360544217687, Blast_Score=97, Evalue=3e-21, Organism=Saccharomyces cerevisiae, GI6323562, Length=149, Percent_Identity=40.9395973154362, Blast_Score=94, Evalue=3e-20, Organism=Saccharomyces cerevisiae, GI6323246, Length=170, Percent_Identity=34.7058823529412, Blast_Score=91, Evalue=3e-19, Organism=Saccharomyces cerevisiae, GI6320510, Length=135, Percent_Identity=42.962962962963, Blast_Score=86, Evalue=5e-18, Organism=Saccharomyces cerevisiae, GI6321848, Length=139, Percent_Identity=38.8489208633094, Blast_Score=77, Evalue=3e-15, Organism=Saccharomyces cerevisiae, GI6322492, Length=165, Percent_Identity=31.5151515151515, Blast_Score=68, Evalue=1e-12, Organism=Drosophila melanogaster, GI17986117, Length=141, Percent_Identity=42.5531914893617, Blast_Score=127, Evalue=9e-30, Organism=Drosophila melanogaster, GI19922376, Length=135, Percent_Identity=42.2222222222222, Blast_Score=122, Evalue=3e-28, Organism=Drosophila melanogaster, GI19922912, Length=131, Percent_Identity=46.5648854961832, Blast_Score=117, Evalue=9e-27, Organism=Drosophila melanogaster, GI21357249, Length=166, Percent_Identity=37.3493975903614, Blast_Score=108, Evalue=5e-24, Organism=Drosophila melanogaster, GI24652460, Length=134, Percent_Identity=37.3134328358209, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI20130249, Length=137, Percent_Identity=42.3357664233577, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI17647301, Length=140, Percent_Identity=42.1428571428571, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI21355677, Length=137, Percent_Identity=37.956204379562, Blast_Score=92, Evalue=4e-19, Organism=Drosophila melanogaster, GI24586038, Length=141, Percent_Identity=39.7163120567376, Blast_Score=91, Evalue=8e-19, Organism=Drosophila melanogaster, GI45549139, Length=133, Percent_Identity=40.6015037593985, Blast_Score=88, Evalue=5e-18, Organism=Drosophila melanogaster, GI24664125, Length=133, Percent_Identity=39.8496240601504, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI21357783, Length=133, Percent_Identity=39.8496240601504, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI17136360, Length=132, Percent_Identity=39.3939393939394, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24650807, Length=141, Percent_Identity=38.2978723404255, Blast_Score=79, Evalue=4e-15,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015891 - InterPro: IPR020892 - InterPro: IPR002130 [H]
Pfam domain/function: PF00160 Pro_isomerase [H]
EC number: =5.2.1.8 [H]
Molecular weight: Translated: 27135; Mature: 27135
Theoretical pI: Translated: 5.08; Mature: 5.08
Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKQAALLLTVLLALTACQKKDAAATSQTETATTDTKTDTGTDAAKTAEVTAPGPIPAGYT CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEECCCCCCCCCE LVPFLTDQPVRAFKAEPAMTLQAGKDYYALIDTNRGQILADLYEQETPVTVNNFVTLARN EEEECCCCCHHHHCCCCCEEEECCCCEEEEEECCCCCCHHHHHHCCCCEEHHHHHHHHHH HFYDGLRFHRVIDGFMAQTGDPKSADEAKKAEWGTGGPGYQFADEFRSKLTFDSPGILAM HHHCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCEEEE ANSGPATNGSQFFITFAPTDFLNGRHTIFGKVISGDDVLDKLTRTSDTSSGSETPIPGAV ECCCCCCCCCEEEEEECCHHHCCCCEEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCC PDKILTVRILTKGS CCCEEEEEEEECCC >Mature Secondary Structure MKQAALLLTVLLALTACQKKDAAATSQTETATTDTKTDTGTDAAKTAEVTAPGPIPAGYT CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEECCCCCCCCCE LVPFLTDQPVRAFKAEPAMTLQAGKDYYALIDTNRGQILADLYEQETPVTVNNFVTLARN EEEECCCCCHHHHCCCCCEEEECCCCEEEEEECCCCCCHHHHHHCCCCEEHHHHHHHHHH HFYDGLRFHRVIDGFMAQTGDPKSADEAKKAEWGTGGPGYQFADEFRSKLTFDSPGILAM HHHCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCEEEE ANSGPATNGSQFFITFAPTDFLNGRHTIFGKVISGDDVLDKLTRTSDTSSGSETPIPGAV ECCCCCCCCCEEEEEECCHHHCCCCEEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCC PDKILTVRILTKGS CCCEEEEEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9317025; 9665876 [H]