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The map label for this gene is sdaAA [H]

Identifier: 94985432

GI number: 94985432

Start: 1414504

End: 1415394

Strand: Reverse

Name: sdaAA [H]

Synonym: Dgeo_1331

Alternate gene names: 94985432

Gene position: 1415394-1414504 (Counterclockwise)

Preceding gene: 94985433

Following gene: 94985429

Centisome position: 57.37

GC content: 69.47

Gene sequence:

>891_bases
ATGACGCTCGAAGAACTGATGAATGCTCCTGCGCCCGCCTCGAGCTGGGTGCTGGCGCAGGATTGCCAGGAAACCGGCCT
AGACCCCCACGACATCCGCGCCGAGATGGCCCGCCGCCTCCGTGAGATGCGGGCCTCGATCGAGCGCGGCCTGAACAGCG
ACGCCAAAAGCATCACCGGGATGGTGGGCTGGAACGCCAAGGGCCTCTGGGACGCGCCTGATGTGTTGGGGGCGCCGCTG
CTGAAGCGCGTGCAGGCCTACGCTATGGCGGTGAATGAGGAAAACGCCCGGATGGGCCGCATCGTTGCCGCCCCCACCGC
GGGCAGCGCGGGCACCATTCCCGGCGCCCTGATCGGCGTGGCCGACCATCTGGGCCTCCCCGACGAGCGGTTGGTGGATC
CCTTGATTCTGGCTGCTGGGGTGGGCAAGGCGATCAGCAAGCGTATGTTCATTTCCGGGGCGGCGGGTGGCTGTCAGGCC
GAGATCGGCTCCAGCGCAGCGATGGCCGCCGCCGCCGTCACTGAGCTGCTGGGCGGAACGCCGCGCGCCTGTGTTCACGC
GGCGTCCCTGGCGCTGATGAACACCATCGGGCTGGTGTGTGACCCGGTGGGCGGCTACGTGGAGGTGCCGTGCGTGAGCC
GCAATGCCTTCTACGCGGTCCACGCTGTCAGCGCGGCGCAGCTCGCCCTGGCGCAGCTCGAGTCCTTCATCCCGCCCGAC
GAGGTGCTGGGCGCAATGGCCTCGGTGGGCCGCATGATGCCCCCCGAACTCCGCGAGACGGCCGAAGGTGGCCTGGCCCA
GACGCCAACCGGTTTGGCCGTGGCCGCGCGGATGGAAGGGAAGGAGGGCGGGGAACAGCCCAGCGGGATGGTGGAACTGC
CGCTGGCCTAG

Upstream 100 bases:

>100_bases
CGCGGAAGCCCTCGCCTTTTTGAACCGCTGGCCCGATACCAATTGGGTGCGCCTGCTGCCCAAACTGATGGAAGGCTAAG
CCGCGCTCCAGGAGCCCTTG

Downstream 100 bases:

>100_bases
TTCCGGTGCTCACACCTGCACGCCGAGTCCCAAGGCCCCGCGCAGTTCGGCATGTGAGGCCAGCACCCGCACCGCGCCCG
CCTCGCGGAGGGCTGGCGCG

Product: L-serine dehydratase, iron-sulfur-dependent, alpha subunit

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MTLEELMNAPAPASSWVLAQDCQETGLDPHDIRAEMARRLREMRASIERGLNSDAKSITGMVGWNAKGLWDAPDVLGAPL
LKRVQAYAMAVNEENARMGRIVAAPTAGSAGTIPGALIGVADHLGLPDERLVDPLILAAGVGKAISKRMFISGAAGGCQA
EIGSSAAMAAAAVTELLGGTPRACVHAASLALMNTIGLVCDPVGGYVEVPCVSRNAFYAVHAVSAAQLALAQLESFIPPD
EVLGAMASVGRMMPPELRETAEGGLAQTPTGLAVAARMEGKEGGEQPSGMVELPLA

Sequences:

>Translated_296_residues
MTLEELMNAPAPASSWVLAQDCQETGLDPHDIRAEMARRLREMRASIERGLNSDAKSITGMVGWNAKGLWDAPDVLGAPL
LKRVQAYAMAVNEENARMGRIVAAPTAGSAGTIPGALIGVADHLGLPDERLVDPLILAAGVGKAISKRMFISGAAGGCQA
EIGSSAAMAAAAVTELLGGTPRACVHAASLALMNTIGLVCDPVGGYVEVPCVSRNAFYAVHAVSAAQLALAQLESFIPPD
EVLGAMASVGRMMPPELRETAEGGLAQTPTGLAVAARMEGKEGGEQPSGMVELPLA
>Mature_295_residues
TLEELMNAPAPASSWVLAQDCQETGLDPHDIRAEMARRLREMRASIERGLNSDAKSITGMVGWNAKGLWDAPDVLGAPLL
KRVQAYAMAVNEENARMGRIVAAPTAGSAGTIPGALIGVADHLGLPDERLVDPLILAAGVGKAISKRMFISGAAGGCQAE
IGSSAAMAAAAVTELLGGTPRACVHAASLALMNTIGLVCDPVGGYVEVPCVSRNAFYAVHAVSAAQLALAQLESFIPPDE
VLGAMASVGRMMPPELRETAEGGLAQTPTGLAVAARMEGKEGGEQPSGMVELPLA

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=246, Percent_Identity=39.0243902439024, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789161, Length=287, Percent_Identity=35.8885017421603, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788116, Length=288, Percent_Identity=34.7222222222222, Blast_Score=138, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 30415; Mature: 30284

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLEELMNAPAPASSWVLAQDCQETGLDPHDIRAEMARRLREMRASIERGLNSDAKSITG
CCHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
MVGWNAKGLWDAPDVLGAPLLKRVQAYAMAVNEENARMGRIVAAPTAGSAGTIPGALIGV
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCEEEECCCCCCCCCCCHHHHHH
ADHLGLPDERLVDPLILAAGVGKAISKRMFISGAAGGCQAEIGSSAAMAAAAVTELLGGT
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHCCHHHHHHHHHHHHHCCC
PRACVHAASLALMNTIGLVCDPVGGYVEVPCVSRNAFYAVHAVSAAQLALAQLESFIPPD
HHHHHHHHHHHHHHHHHHHCCCCCCEEECCEECCCCEEHHHHHHHHHHHHHHHHHCCCHH
EVLGAMASVGRMMPPELRETAEGGLAQTPTGLAVAARMEGKEGGEQPSGMVELPLA
HHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCEEECCCC
>Mature Secondary Structure 
TLEELMNAPAPASSWVLAQDCQETGLDPHDIRAEMARRLREMRASIERGLNSDAKSITG
CHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
MVGWNAKGLWDAPDVLGAPLLKRVQAYAMAVNEENARMGRIVAAPTAGSAGTIPGALIGV
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCEEEECCCCCCCCCCCHHHHHH
ADHLGLPDERLVDPLILAAGVGKAISKRMFISGAAGGCQAEIGSSAAMAAAAVTELLGGT
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHCCHHHHHHHHHHHHHCCC
PRACVHAASLALMNTIGLVCDPVGGYVEVPCVSRNAFYAVHAVSAAQLALAQLESFIPPD
HHHHHHHHHHHHHHHHHHHCCCCCCEEECCEECCCCEEHHHHHHHHHHHHHHHHHCCCHH
EVLGAMASVGRMMPPELRETAEGGLAQTPTGLAVAARMEGKEGGEQPSGMVELPLA
HHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]