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The map label for this gene is ctaC [H]

Identifier: 94984515

GI number: 94984515

Start: 415361

End: 416668

Strand: Reverse

Name: ctaC [H]

Synonym: Dgeo_0407

Alternate gene names: 94984515

Gene position: 416668-415361 (Counterclockwise)

Preceding gene: 94984516

Following gene: 94984514

Centisome position: 16.89

GC content: 63.91

Gene sequence:

>1308_bases
GTGTCAGGTGCATCGGCGCAAAACCCAAGGCAACGCTTTAGACTGAACGCGAAGAAAGGAGTGATGTTGAACACCAAGCA
TAGCCGCCACAGACGTGGACAACGGAGGGGCGGGTTCCCCCGATGGGCGCGCGCCGGACTGCTGGGCATGGCTGCGGCGC
TGCTGACAGGCTGTCAGTCACAACAGCTGCTCACCCTCGGTGACATGAGTTCGGCGTACAACCGCGAGATCCTGTGGATG
AGCATCCCGGCCATCGCGCTCTCGATCATCATCTTTGTCGGGGTGTCATGGGCGCTGTTCTATACGGTGCGCAAGTTCCG
GGAGGAGAACAATGACGCGCCGCCCGCACAGTTCCACGGCAACAACCGCCTGGAGACCATCTTGGTGGTCGTGCCGGTGA
TCATCGTGATGCTGCTCAGCGTGCTCGCGGTGCGCTCGCTGGCCCGCCTGAACCCTGTGCCGCAGGACGCGGAGAAGATT
GACGTGCTGGGCAAACAGTTCTGGTGGAACTTCAGCTATCCCGGAGCACCCGCAGCGGCAGGTGGCAACGTCACCAACGG
CAACGAACTGGTGCTGCCCACCGGGAAGTGGGCCTCTCTGACCATCACCAGTGGCGACGTGATTCATGCTTTCTGGGCGC
CCAACCTGGGCGGGCAGCGTGACGCTACCCCCGGGACTCAGAAAACCTGGCAGATCCAGACAGACCGCGCTGGGGTCTAT
CAGGGCAACTGCAACGTGCTGTGTGGCGCCAGCCACGCGAACATGCGCTTCAAGGTGATCGCGCTGCCGCCGGACCGCTA
CAACAGCTTCCTGACGGCGGCCCAAGCGTACCGCGCGCCTACTCCTGCCCCCGGCAGCGCCGAAGAACGCGGCTATACGC
TGTTCACCCAGGGCAAGCCTTCCACGGGCGCGCTGGCCTGCGCGGCTTGCCACCGCGTGCAAGGCACCCCGGCCAATGGT
CAGGCGGGGCCCGACCTGAGCTTTTTCGGCACCCGCCGCACCCTGGGGGCAGGCATGTGGGAAGCGCTGACCCCGCAGCA
TTGGGAAGCACCCCAAGCCGCGGCTGAGCTGCATGCCTGGATCAAGAACAGCCCGGCACAGAAGCCCGGGAGCCTGATGC
CCCCCTACGATGGCAGCACCTATACCCTGAATGGCAAGACGCAGAAAGCGGGGCTGTTGACCGATGAGGAGATCAACGAC
ATCGCCGCTTATCTGCGCAGCCTGCGTCTGCCGGAAGAGGCGGACTACTGGCGTGACGTGCCGGTGATCGGTTCGAACAG
CACTGTTGCACAAGGAGGAAACCCATGA

Upstream 100 bases:

>100_bases
GGCCGAAAAGCGGCTGAGGACACTTGCCCGCCCCTCAATCTGGTCTCATGCTGGGTATGCCTGACCGGTCGGTCGAACCA
CTTGGAGGCGCCGCGCAGCG

Downstream 100 bases:

>100_bases
CGGTCCAGCACGCACCGCAGACCGTGGTCACCCCACGCCGGGGGGCCTGGGAAGTCATCAAGGACTACATGATGACGACC
GATCACAAAAAGATCGGGCT

Product: cytochrome c oxidase, subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MSGASAQNPRQRFRLNAKKGVMLNTKHSRHRRGQRRGGFPRWARAGLLGMAAALLTGCQSQQLLTLGDMSSAYNREILWM
SIPAIALSIIIFVGVSWALFYTVRKFREENNDAPPAQFHGNNRLETILVVVPVIIVMLLSVLAVRSLARLNPVPQDAEKI
DVLGKQFWWNFSYPGAPAAAGGNVTNGNELVLPTGKWASLTITSGDVIHAFWAPNLGGQRDATPGTQKTWQIQTDRAGVY
QGNCNVLCGASHANMRFKVIALPPDRYNSFLTAAQAYRAPTPAPGSAEERGYTLFTQGKPSTGALACAACHRVQGTPANG
QAGPDLSFFGTRRTLGAGMWEALTPQHWEAPQAAAELHAWIKNSPAQKPGSLMPPYDGSTYTLNGKTQKAGLLTDEEIND
IAAYLRSLRLPEEADYWRDVPVIGSNSTVAQGGNP

Sequences:

>Translated_435_residues
MSGASAQNPRQRFRLNAKKGVMLNTKHSRHRRGQRRGGFPRWARAGLLGMAAALLTGCQSQQLLTLGDMSSAYNREILWM
SIPAIALSIIIFVGVSWALFYTVRKFREENNDAPPAQFHGNNRLETILVVVPVIIVMLLSVLAVRSLARLNPVPQDAEKI
DVLGKQFWWNFSYPGAPAAAGGNVTNGNELVLPTGKWASLTITSGDVIHAFWAPNLGGQRDATPGTQKTWQIQTDRAGVY
QGNCNVLCGASHANMRFKVIALPPDRYNSFLTAAQAYRAPTPAPGSAEERGYTLFTQGKPSTGALACAACHRVQGTPANG
QAGPDLSFFGTRRTLGAGMWEALTPQHWEAPQAAAELHAWIKNSPAQKPGSLMPPYDGSTYTLNGKTQKAGLLTDEEIND
IAAYLRSLRLPEEADYWRDVPVIGSNSTVAQGGNP
>Mature_434_residues
SGASAQNPRQRFRLNAKKGVMLNTKHSRHRRGQRRGGFPRWARAGLLGMAAALLTGCQSQQLLTLGDMSSAYNREILWMS
IPAIALSIIIFVGVSWALFYTVRKFREENNDAPPAQFHGNNRLETILVVVPVIIVMLLSVLAVRSLARLNPVPQDAEKID
VLGKQFWWNFSYPGAPAAAGGNVTNGNELVLPTGKWASLTITSGDVIHAFWAPNLGGQRDATPGTQKTWQIQTDRAGVYQ
GNCNVLCGASHANMRFKVIALPPDRYNSFLTAAQAYRAPTPAPGSAEERGYTLFTQGKPSTGALACAACHRVQGTPANGQ
AGPDLSFFGTRRTLGAGMWEALTPQHWEAPQAAAELHAWIKNSPAQKPGSLMPPYDGSTYTLNGKTQKAGLLTDEEINDI
AAYLRSLRLPEEADYWRDVPVIGSNSTVAQGGNP

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=161, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1786635, Length=223, Percent_Identity=27.3542600896861, Blast_Score=79, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6226540, Length=202, Percent_Identity=28.2178217821782, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM; PF00034 Cytochrom_C [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 47144; Mature: 47013

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGASAQNPRQRFRLNAKKGVMLNTKHSRHRRGQRRGGFPRWARAGLLGMAAALLTGCQS
CCCCCCCCCHHHHEECCCCCEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
QQLLTLGDMSSAYNREILWMSIPAIALSIIIFVGVSWALFYTVRKFREENNDAPPAQFHG
CCEEEECCCCHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NNRLETILVVVPVIIVMLLSVLAVRSLARLNPVPQDAEKIDVLGKQFWWNFSYPGAPAAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEECCCCCCCCCCC
GGNVTNGNELVLPTGKWASLTITSGDVIHAFWAPNLGGQRDATPGTQKTWQIQTDRAGVY
CCCCCCCCEEEEECCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCEE
QGNCNVLCGASHANMRFKVIALPPDRYNSFLTAAQAYRAPTPAPGSAEERGYTLFTQGKP
ECCCCEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCC
STGALACAACHRVQGTPANGQAGPDLSFFGTRRTLGAGMWEALTPQHWEAPQAAAELHAW
CCCHHHHHHHHHCCCCCCCCCCCCCCCEECCHHHHHCCHHHHCCCCCCCCHHHHHHHHHH
IKNSPAQKPGSLMPPYDGSTYTLNGKTQKAGLLTDEEINDIAAYLRSLRLPEEADYWRDV
HHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCC
PVIGSNSTVAQGGNP
CEECCCCCCCCCCCC
>Mature Secondary Structure 
SGASAQNPRQRFRLNAKKGVMLNTKHSRHRRGQRRGGFPRWARAGLLGMAAALLTGCQS
CCCCCCCCHHHHEECCCCCEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
QQLLTLGDMSSAYNREILWMSIPAIALSIIIFVGVSWALFYTVRKFREENNDAPPAQFHG
CCEEEECCCCHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NNRLETILVVVPVIIVMLLSVLAVRSLARLNPVPQDAEKIDVLGKQFWWNFSYPGAPAAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEECCCCCCCCCCC
GGNVTNGNELVLPTGKWASLTITSGDVIHAFWAPNLGGQRDATPGTQKTWQIQTDRAGVY
CCCCCCCCEEEEECCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCEE
QGNCNVLCGASHANMRFKVIALPPDRYNSFLTAAQAYRAPTPAPGSAEERGYTLFTQGKP
ECCCCEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCC
STGALACAACHRVQGTPANGQAGPDLSFFGTRRTLGAGMWEALTPQHWEAPQAAAELHAW
CCCHHHHHHHHHCCCCCCCCCCCCCCCEECCHHHHHCCHHHHCCCCCCCCHHHHHHHHHH
IKNSPAQKPGSLMPPYDGSTYTLNGKTQKAGLLTDEEINDIAAYLRSLRLPEEADYWRDV
HHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCC
PVIGSNSTVAQGGNP
CEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7678007 [H]