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The map label for this gene is caaA [H]

Identifier: 94984514

GI number: 94984514

Start: 412908

End: 415364

Strand: Reverse

Name: caaA [H]

Synonym: Dgeo_0406

Alternate gene names: 94984514

Gene position: 415364-412908 (Counterclockwise)

Preceding gene: 94984515

Following gene: 94984513

Centisome position: 16.84

GC content: 61.54

Gene sequence:

>2457_bases
ATGACGGTCCAGCACGCACCGCAGACCGTGGTCACCCCACGCCGGGGGGCCTGGGAAGTCATCAAGGACTACATGATGAC
GACCGATCACAAAAAGATCGGGCTGCTCTACATCATGACCTCCATTCTGGCCTTTGGCATCGGCGGTCTTCTGGCTGTGG
CCATTCGGTTGCAACTGGCGCTGCCGAACGAGACCTTCCTGGTCGGCCACCTCTACAACCAGGTCTTGACCCTGCACGCC
GCGGTCATGATCTTCTTCTTTCTGATTCCGATTGGGCTGTTCGGCTTCGGAAACTTCTTGCTGCCGCTGCAACTCGGGGT
GCGCGACGTGGCGCTGCCGCGCGTCAACACCTTTGCCGTGTGGCTTTTTATCTTCAGTCTGATTCTGGTGATCACTGGCC
TGTGGAATGGCGGCGCGCCGGGGGTGGGTTGGACCTTCTACTATCCCCTCTCGGTGGATGCCAACCAGACGGGCGTGAGC
GTGTTCATGGTCGCGCTGATCCTGAACGGCATCGGATCTCTGCTGGGCAGCGCAAACTTCGCCGCTACCGTCATCAACAT
GCGTGCTCCCGGCATGGGCCTGTGGAAGATGCCCATCTTTACCTGGAGCATCTTTGCCACCAGTCTGCTGCAGCTGGTGA
GCCTGGGCGGCCTGACGGCCGCGGCGCTGGTCACCTACCTGGAAATCAAGCTGGGCCTCTCAATGTTTAATCCCGGCATC
GGGGGCACGCCCATCCTGATGCAGCAGTTCTTCTGGTTCTACTCGCACCCCGCCGTGTACGTGATGCTGCTCCCCTATCT
GGGAATTGCAGCGGAAATCGCCTCAACCTTTGCCCGCAAGCCGCTGTTCGGCTACCGCGTGATGGTGTACTCGCTGCTGG
GCATTGTGCTGGTCTCGCTGCTGGTGTGGGCGCACCACATGTTCGCGGTGGGCCTGCCGGAATCCTGGCAGATCGCTTTC
GCGGTGGCGACCCTGCTGGTGGCCGTCCCCACCGGCGTCAAGATTTTCAACCTGATCGGCACGCTGTGGGGCGGGCGCAT
CCTGATGAAGACGCCAACATACTGGCTGGTGGGCTTTATCTTCAACTTCCTGGTGGGCGGCATCACCGGTGTGTCGCTGG
GCATGATTCCCTTTGACTACCAGGTCACGATGTCCTACTACGTGGTGGCGCACTTCCACAACGTGATGATGTTCGGCACG
GCCTTCCTTGCCTTCGGCGGCATCGCCTACTGGTGGCCCAAGATGACCGGGCGCTTCCTGGATGAGAAGCTGGGCCTGTG
GCACTTCTGGCTGGTCATGGTCGGCTCGTGGATGACCTTCTTGCCGCAGTACATCCTGGGCCTGCTCGGGATGCCCCGCC
GCTACTACACCTACCCGGCAGGCAACTTTGCCTGGACCGAGCTGAACTTCATCTCCACCCTGGGCGCGCTGACGCTACTG
GCGGGCGGTCTGGTGTGGGCTTACAACATGCTGCAGAGCCTGCGGCGCCCCATCACCGCCAGTCCCAACCCCTGGGGCGG
CTTCACGCTGGAGTGGACGGCGGCTTCGCCCCCGGCCCCCTACAACTTTGCCCACGAGTTCCCCCGCAACTTCCCCACCG
AGCGGCCTCTCTACGACTGGGAAAAGAACGGCGAGAAGCTGATTCCGGTGGACCCCAAGACCATTCACCTGCCGCAGGAC
TCCATCTGGCCCTTCATGACGGCCTTCTCGCTGCTGCTGATGGGGTATGGCCTCTCCTTCGGCTGGTTCACCAACTACAC
TCCGGCGGGCGGCCTGCAACCCTTCTTCAGTGCTCCCCCCAGCCACGTGTTCGCCAGCATCGTGCTGTACCTGAGCATTC
CGCTTTTCCTGTACTCGCTGTTCAAGTGGGCCGGGACGCGGGAATACGCGGTGCCGGTCGAGCATCACCACCTCACCAAG
TACGACAACGGCTTTATGGGGATGGCCTGGTTCATCCTCTCGGAAGTCGGGCTCTTCGGCGTGCTGATCGCTGGGTATGT
GTACCTGCGCATCAGCGGCCATGCCGAACCGCCCGCGATGCGCCCGAGCATCTGGCTGGCTGCGCTCAACACCCTGATTC
TGGTCACCTCGTCCTTTGTGATCCACAAGGCCGAACAGGACCATCATCACGGGCGTTACACCTGGTTCCGGCTGGGCCTC
TTCATCACCCTGCTGCTGGGGACCCTCTTCATGATCTTCCAGGTGTACGAGTTCTCGCTGTTCGGGACCGAGAGTGACTG
GAAGCAAAACCTCTGGCAGTCGTGCTTTTTCATCATCGTCGGCCTGCACGGTCTGCACATCCTGATTGGCGGCACCGGCG
TAGCCCTGCCGTACTATCAGGCCCTGACCGGCAAGATGGACAAGTACAACCACGGTTCGACCGCGCCCGCCAGCCTGTAC
TGGCACCTGGTGGACGTGGTGTGGCTCTTCATCGTGGCGATCTTCTACGCCTGGTAG

Upstream 100 bases:

>100_bases
CCGCTTATCTGCGCAGCCTGCGTCTGCCGGAAGAGGCGGACTACTGGCGTGACGTGCCGGTGATCGGTTCGAACAGCACT
GTTGCACAAGGAGGAAACCC

Downstream 100 bases:

>100_bases
AGGCATGAGGTTTTCAGCGGGCGGGGACGTGCAGAAGCGTTCCCGCCCGCCTCTATGCCGAACGCCCCAGCCCTTATCCC
TTCCCCAGGGACACCCTGCC

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome c aa(3) subunit 1; A-protein; Cytochrome caa3 [H]

Number of amino acids: Translated: 818; Mature: 817

Protein sequence:

>818_residues
MTVQHAPQTVVTPRRGAWEVIKDYMMTTDHKKIGLLYIMTSILAFGIGGLLAVAIRLQLALPNETFLVGHLYNQVLTLHA
AVMIFFFLIPIGLFGFGNFLLPLQLGVRDVALPRVNTFAVWLFIFSLILVITGLWNGGAPGVGWTFYYPLSVDANQTGVS
VFMVALILNGIGSLLGSANFAATVINMRAPGMGLWKMPIFTWSIFATSLLQLVSLGGLTAAALVTYLEIKLGLSMFNPGI
GGTPILMQQFFWFYSHPAVYVMLLPYLGIAAEIASTFARKPLFGYRVMVYSLLGIVLVSLLVWAHHMFAVGLPESWQIAF
AVATLLVAVPTGVKIFNLIGTLWGGRILMKTPTYWLVGFIFNFLVGGITGVSLGMIPFDYQVTMSYYVVAHFHNVMMFGT
AFLAFGGIAYWWPKMTGRFLDEKLGLWHFWLVMVGSWMTFLPQYILGLLGMPRRYYTYPAGNFAWTELNFISTLGALTLL
AGGLVWAYNMLQSLRRPITASPNPWGGFTLEWTAASPPAPYNFAHEFPRNFPTERPLYDWEKNGEKLIPVDPKTIHLPQD
SIWPFMTAFSLLLMGYGLSFGWFTNYTPAGGLQPFFSAPPSHVFASIVLYLSIPLFLYSLFKWAGTREYAVPVEHHHLTK
YDNGFMGMAWFILSEVGLFGVLIAGYVYLRISGHAEPPAMRPSIWLAALNTLILVTSSFVIHKAEQDHHHGRYTWFRLGL
FITLLLGTLFMIFQVYEFSLFGTESDWKQNLWQSCFFIIVGLHGLHILIGGTGVALPYYQALTGKMDKYNHGSTAPASLY
WHLVDVVWLFIVAIFYAW

Sequences:

>Translated_818_residues
MTVQHAPQTVVTPRRGAWEVIKDYMMTTDHKKIGLLYIMTSILAFGIGGLLAVAIRLQLALPNETFLVGHLYNQVLTLHA
AVMIFFFLIPIGLFGFGNFLLPLQLGVRDVALPRVNTFAVWLFIFSLILVITGLWNGGAPGVGWTFYYPLSVDANQTGVS
VFMVALILNGIGSLLGSANFAATVINMRAPGMGLWKMPIFTWSIFATSLLQLVSLGGLTAAALVTYLEIKLGLSMFNPGI
GGTPILMQQFFWFYSHPAVYVMLLPYLGIAAEIASTFARKPLFGYRVMVYSLLGIVLVSLLVWAHHMFAVGLPESWQIAF
AVATLLVAVPTGVKIFNLIGTLWGGRILMKTPTYWLVGFIFNFLVGGITGVSLGMIPFDYQVTMSYYVVAHFHNVMMFGT
AFLAFGGIAYWWPKMTGRFLDEKLGLWHFWLVMVGSWMTFLPQYILGLLGMPRRYYTYPAGNFAWTELNFISTLGALTLL
AGGLVWAYNMLQSLRRPITASPNPWGGFTLEWTAASPPAPYNFAHEFPRNFPTERPLYDWEKNGEKLIPVDPKTIHLPQD
SIWPFMTAFSLLLMGYGLSFGWFTNYTPAGGLQPFFSAPPSHVFASIVLYLSIPLFLYSLFKWAGTREYAVPVEHHHLTK
YDNGFMGMAWFILSEVGLFGVLIAGYVYLRISGHAEPPAMRPSIWLAALNTLILVTSSFVIHKAEQDHHHGRYTWFRLGL
FITLLLGTLFMIFQVYEFSLFGTESDWKQNLWQSCFFIIVGLHGLHILIGGTGVALPYYQALTGKMDKYNHGSTAPASLY
WHLVDVVWLFIVAIFYAW
>Mature_817_residues
TVQHAPQTVVTPRRGAWEVIKDYMMTTDHKKIGLLYIMTSILAFGIGGLLAVAIRLQLALPNETFLVGHLYNQVLTLHAA
VMIFFFLIPIGLFGFGNFLLPLQLGVRDVALPRVNTFAVWLFIFSLILVITGLWNGGAPGVGWTFYYPLSVDANQTGVSV
FMVALILNGIGSLLGSANFAATVINMRAPGMGLWKMPIFTWSIFATSLLQLVSLGGLTAAALVTYLEIKLGLSMFNPGIG
GTPILMQQFFWFYSHPAVYVMLLPYLGIAAEIASTFARKPLFGYRVMVYSLLGIVLVSLLVWAHHMFAVGLPESWQIAFA
VATLLVAVPTGVKIFNLIGTLWGGRILMKTPTYWLVGFIFNFLVGGITGVSLGMIPFDYQVTMSYYVVAHFHNVMMFGTA
FLAFGGIAYWWPKMTGRFLDEKLGLWHFWLVMVGSWMTFLPQYILGLLGMPRRYYTYPAGNFAWTELNFISTLGALTLLA
GGLVWAYNMLQSLRRPITASPNPWGGFTLEWTAASPPAPYNFAHEFPRNFPTERPLYDWEKNGEKLIPVDPKTIHLPQDS
IWPFMTAFSLLLMGYGLSFGWFTNYTPAGGLQPFFSAPPSHVFASIVLYLSIPLFLYSLFKWAGTREYAVPVEHHHLTKY
DNGFMGMAWFILSEVGLFGVLIAGYVYLRISGHAEPPAMRPSIWLAALNTLILVTSSFVIHKAEQDHHHGRYTWFRLGLF
ITLLLGTLFMIFQVYEFSLFGTESDWKQNLWQSCFFIIVGLHGLHILIGGTGVALPYYQALTGKMDKYNHGSTAPASLYW
HLVDVVWLFIVAIFYAW

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=522, Percent_Identity=37.9310344827586, Blast_Score=322, Evalue=1e-87,
Organism=Homo sapiens, GI251831113, Length=272, Percent_Identity=27.5735294117647, Blast_Score=75, Evalue=3e-13,
Organism=Escherichia coli, GI1786634, Length=561, Percent_Identity=37.2549019607843, Blast_Score=346, Evalue=4e-96,
Organism=Saccharomyces cerevisiae, GI6226519, Length=461, Percent_Identity=40.1301518438178, Blast_Score=334, Evalue=3e-92,
Organism=Saccharomyces cerevisiae, GI6226524, Length=322, Percent_Identity=40.9937888198758, Blast_Score=238, Evalue=4e-63,
Organism=Saccharomyces cerevisiae, GI6226523, Length=251, Percent_Identity=37.0517928286853, Blast_Score=139, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241
- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00115 COX1; PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 91646; Mature: 91515

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB ; PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVQHAPQTVVTPRRGAWEVIKDYMMTTDHKKIGLLYIMTSILAFGIGGLLAVAIRLQLA
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
LPNETFLVGHLYNQVLTLHAAVMIFFFLIPIGLFGFGNFLLPLQLGVRDVALPRVNTFAV
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHCCCCHHHHHH
WLFIFSLILVITGLWNGGAPGVGWTFYYPLSVDANQTGVSVFMVALILNGIGSLLGSANF
HHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCH
AATVINMRAPGMGLWKMPIFTWSIFATSLLQLVSLGGLTAAALVTYLEIKLGLSMFNPGI
HEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
GGTPILMQQFFWFYSHPAVYVMLLPYLGIAAEIASTFARKPLFGYRVMVYSLLGIVLVSL
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LVWAHHMFAVGLPESWQIAFAVATLLVAVPTGVKIFNLIGTLWGGRILMKTPTYWLVGFI
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEECCHHHHHHHH
FNFLVGGITGVSLGMIPFDYQVTMSYYVVAHFHNVMMFGTAFLAFGGIAYWWPKMTGRFL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
DEKLGLWHFWLVMVGSWMTFLPQYILGLLGMPRRYYTYPAGNFAWTELNFISTLGALTLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEHHHHHHHHHHHHHHH
AGGLVWAYNMLQSLRRPITASPNPWGGFTLEWTAASPPAPYNFAHEFPRNFPTERPLYDW
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCC
EKNGEKLIPVDPKTIHLPQDSIWPFMTAFSLLLMGYGLSFGWFTNYTPAGGLQPFFSAPP
CCCCCEEECCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCH
SHVFASIVLYLSIPLFLYSLFKWAGTREYAVPVEHHHLTKYDNGFMGMAWFILSEVGLFG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VLIAGYVYLRISGHAEPPAMRPSIWLAALNTLILVTSSFVIHKAEQDHHHGRYTWFRLGL
HHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHH
FITLLLGTLFMIFQVYEFSLFGTESDWKQNLWQSCFFIIVGLHGLHILIGGTGVALPYYQ
HHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHH
ALTGKMDKYNHGSTAPASLYWHLVDVVWLFIVAIFYAW
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVQHAPQTVVTPRRGAWEVIKDYMMTTDHKKIGLLYIMTSILAFGIGGLLAVAIRLQLA
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
LPNETFLVGHLYNQVLTLHAAVMIFFFLIPIGLFGFGNFLLPLQLGVRDVALPRVNTFAV
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHCCCCHHHHHH
WLFIFSLILVITGLWNGGAPGVGWTFYYPLSVDANQTGVSVFMVALILNGIGSLLGSANF
HHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCH
AATVINMRAPGMGLWKMPIFTWSIFATSLLQLVSLGGLTAAALVTYLEIKLGLSMFNPGI
HEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
GGTPILMQQFFWFYSHPAVYVMLLPYLGIAAEIASTFARKPLFGYRVMVYSLLGIVLVSL
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LVWAHHMFAVGLPESWQIAFAVATLLVAVPTGVKIFNLIGTLWGGRILMKTPTYWLVGFI
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEECCHHHHHHHH
FNFLVGGITGVSLGMIPFDYQVTMSYYVVAHFHNVMMFGTAFLAFGGIAYWWPKMTGRFL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
DEKLGLWHFWLVMVGSWMTFLPQYILGLLGMPRRYYTYPAGNFAWTELNFISTLGALTLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEHHHHHHHHHHHHHHH
AGGLVWAYNMLQSLRRPITASPNPWGGFTLEWTAASPPAPYNFAHEFPRNFPTERPLYDW
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCC
EKNGEKLIPVDPKTIHLPQDSIWPFMTAFSLLLMGYGLSFGWFTNYTPAGGLQPFFSAPP
CCCCCEEECCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCH
SHVFASIVLYLSIPLFLYSLFKWAGTREYAVPVEHHHLTKYDNGFMGMAWFILSEVGLFG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VLIAGYVYLRISGHAEPPAMRPSIWLAALNTLILVTSSFVIHKAEQDHHHGRYTWFRLGL
HHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHH
FITLLLGTLFMIFQVYEFSLFGTESDWKQNLWQSCFFIIVGLHGLHILIGGTGVALPYYQ
HHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHH
ALTGKMDKYNHGSTAPASLYWHLVDVVWLFIVAIFYAW
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8383670; 10338009 [H]