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The map label for this gene is tdk2 [H]

Identifier: 94994407

GI number: 94994407

Start: 958472

End: 959041

Strand: Direct

Name: tdk2 [H]

Synonym: MGAS10750_Spy1011

Alternate gene names: 94994407

Gene position: 958472-959041 (Clockwise)

Preceding gene: 94994404

Following gene: 94994408

Centisome position: 49.48

GC content: 34.56

Gene sequence:

>570_bases
TTGGCTCAACTCTATTATAAATATGGGACAATGAATTCTGGTAAAACCATTGAAATTTTAAAAGTTGCTCATAACTATGA
AGAACAAGGCAAACCTGTTGTCATTATGACAAGTGCTCTTGATACACGTGATGGTTTTGGCATCGTCTCAAGCCGTATTG
GTATGCGACGAGAAGCTATTCCCATTTCAAATGACATGGATATTTTCACATTTATTGCCCAATTGGAAGAAAAACCTTAT
TGTGTCCTGATTGACGAAAGTCAATTTTTAAGCAAGCAAAATGTTTATGATTTGGCGCGTGTGGTGGATGAGCTAAATGT
TCCTGTCATGGCTTTTGGTTTGAAAAATGATTTCCAAAACAATCTTTTTGAAGGTTCAAAACATTTGCTATTATTGGCCG
ATAAGATTGATGAAATCAAAACAATTTGCCAATACTGTAGTAAGAAAGCAACCATGGTTTTAAGGACAGAAAATGGAAAA
CCTGTCTATGAAGGTGATCAGATACAAATTGGTGGTAATGAAACATATATCCCAGTTTGTCGAAAACATTATTTTAATCC
AGAGATTTAA

Upstream 100 bases:

>100_bases
ATAATGCTGTGAAAAAGTACACACTGTTTTCAATGGCTGGGAAAACTTCAGCCTTTGTGGTAAAATAGGTAGAATACTAT
AGAAAGTAGGATTTTCCGCT

Downstream 100 bases:

>100_bases
AAGGTAATCGGTTTTAAAGGAGATACAAAGAAAAATGAATATTTATGATCAATTGCAGGCAGTTGAAGATCGTTATGAAG
AATTAGGTGAGTTACTTAGT

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRDGFGIVSSRIGMRREAIPISNDMDIFTFIAQLEEKPY
CVLIDESQFLSKQNVYDLARVVDELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGK
PVYEGDQIQIGGNETYIPVCRKHYFNPEI

Sequences:

>Translated_189_residues
MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRDGFGIVSSRIGMRREAIPISNDMDIFTFIAQLEEKPY
CVLIDESQFLSKQNVYDLARVVDELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGK
PVYEGDQIQIGGNETYIPVCRKHYFNPEI
>Mature_188_residues
AQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRDGFGIVSSRIGMRREAIPISNDMDIFTFIAQLEEKPYC
VLIDESQFLSKQNVYDLARVVDELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGKP
VYEGDQIQIGGNETYIPVCRKHYFNPEI

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=187, Percent_Identity=48.6631016042781, Blast_Score=189, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 21547; Mature: 21416

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRDGFGIVSSRIGMRREAI
CCEEEEEECCCCCCCEEEEEEEECCHHHCCCCEEEEEECCCCCCCCCHHHHHCCCCCCCC
PISNDMDIFTFIAQLEEKPYCVLIDESQFLSKQNVYDLARVVDELNVPVMAFGLKNDFQN
CCCCCCHHHHHHHHHCCCCEEEEECCHHHHCCCCHHHHHHHHHHCCCCEEEEECCCHHHH
NLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGKPVYEGDQIQIGGNETYIPVC
HHHCCCCEEEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEECCCCEEEHHH
RKHYFNPEI
HHCCCCCCC
>Mature Secondary Structure 
AQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRDGFGIVSSRIGMRREAI
CEEEEEECCCCCCCEEEEEEEECCHHHCCCCEEEEEECCCCCCCCCHHHHHCCCCCCCC
PISNDMDIFTFIAQLEEKPYCVLIDESQFLSKQNVYDLARVVDELNVPVMAFGLKNDFQN
CCCCCCHHHHHHHHHCCCCEEEEECCHHHHCCCCHHHHHHHHHHCCCCEEEEECCCHHHH
NLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGKPVYEGDQIQIGGNETYIPVC
HHHCCCCEEEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEECCCCEEEHHH
RKHYFNPEI
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA