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The map label for this gene is bglP [H]

Identifier: 94993893

GI number: 94993893

Start: 479459

End: 481321

Strand: Direct

Name: bglP [H]

Synonym: MGAS10750_Spy0497

Alternate gene names: 94993893

Gene position: 479459-481321 (Clockwise)

Preceding gene: 94993892

Following gene: 94993894

Centisome position: 24.75

GC content: 43.37

Gene sequence:

>1863_bases
ATGACGTATCAAGAAACTGCCAAGGCTATTTTAGCGGCGGTTGGTGGCAAAACAAATATTCAACGTGTGACACACTGTGT
AACACGTCTACGCTTAGTACTGAAAAATGATGAGAAAGTTAAAGATCAGCAAGTCAAAGCCATTTCAAATGTGATTGGTG
TGATGCGCAAAAACGGCCAGTACCAAATTATCTTGGGCAATGATGTCAATAATTATTACCAAGCCTTTTTAAGCCTAGGG
CATTTTGACAATCAAGATGAAGATCATTCTTCAAAAGCGAAAGGAAGTATCCTTGAGCGCTTGATTGAAACCATTGCTGG
CGTGATTACACCGCTGATTCCAGCCCTTCTTGGTGGTGGAATGCTCAAAGTGGTGGGAATCTTGCTTACTATGCTTGGCT
TAGCGAGTGCGGACTCTCAAACCGTTGCCTTTATTAACTTCTTTGGCGATGCGGCTTATTATTTTATGCCTGTCATGATT
GCCTATTCAGCAGCGGCGCGCTTTAAGGTGACACCTATTTTAGCAGCGACGATCGCAGGGATTTTATTGCATCCTGCCTT
TGTTGCAATGGTAGCAGAAGGTAAACCATTGGCTTTATTTGGAGCACCAGTCACTCCTGCTAGCTATGGCTCATCTGTTA
TTCCCATTTTGATGATGGTTTACTTGATGCAATACATTGAAAAATGGGTCAATCGCTTGGTGCCAAGCGTGATGAAAAGC
TTCTTACAGCCAACCTTAATCATTTTGATTTCTGGCTTTTTGGCTTTAGTGGTTGTAGGTCCTCTTGGTGTGATTATTGG
TCAAGGGTTATCTAATACCATGCTCGCTATTTATCATGTGGCTCCGTGGCTAGCACTTGCCATTTTGGGAGCGATTATGC
CGCTTGTTGTCATGACGGGGATGCACTGGGCTTTTGCACCAATCTTTTTGGCCGCTTCGGTCGCAACACCAGATGTCTTG
ATTTTACCAGCAATGTTGGCTTCTAATTTGGCTCAAGGAGCCGCATCTTTGGCTGTTGCCTTTAAAACAAAGCAGAAACA
AACACGTCAAGTTGCCCTTGCCGCGGGGATTTCAGCTTTGCTGGCAGGTATCACGGAACCGGCACTTTATGGGGTCACAC
TGAAATTTAAAAAGCCACTCTATGCAGCCATGATTTCAGGTGGTCTGGTCGGAGCCTTTATTGGTTTTGTCAATATTGCT
TCTTATACCTTTGTCGTACCTTCTATTATTGGTTTACCACAGTACATCAACCCATCAGGCGGAGCTAATTTTACAAATGC
TTTGATTGCCGGAGCTGCGACGATTGTGTTAGCCTTCAGTTTGACTTGGTTCATGGGAATTGATGAAGAATCCCCAGAGC
AAGTGAGTGTTGCAGTAGATATGTCACAAGTTAAGAGCGGCTTGTCAACCAAACAAACGTTGTATGCTCCAATGACAGGT
GAGATGCTTTTTCTATCAGAAGTTCCTGATGAAACCTTTTCTTCCAAGTTATTAGGAGAAGGATTTGCCATATTACCAAG
CGAAGGTGTGGTCTATGCCCCCTTTGATGGTGAAGTCATCACTTTCTTTCCAACCAAGCATGCTGTTGCCTTAAAAAACA
CACGTGGTGTGGAAGTCTTGATTCATGTCGGTATTGATACGGTTGAGTTAAAAGGGCAAGGTTTCGAGCAGTTAGTGTCT
GTTGGCGATGTCGTGAAACGAGGCCAGGCACTTCTAAAAATGGATACTGATTTCATTACTTCAAAAGGCTATTCACTCAT
CAGTCCTGTGGTCGTGACCAATTCGGCTGAGCAGTTGGAGATTATTATTCAAGATGACAAAAAAATGGTGACTAAAGAGG
ACGCTTTGTTAGTCATTTTATAA

Upstream 100 bases:

>100_bases
GAGATAAAAAAGCGGTACAACTACCACCTTAATTCAAGCGAACTTTTGTATTTGACGGTTCATGTTAAACGTTTAGTGAA
ACATTTAAAGGAGACTTAAT

Downstream 100 bases:

>100_bases
CCTAAAAGGAGAGGGAGAATGGGAATTTTTTCAAAAGATTTCTTATGGGGCGGCGCAGTAGCTGCCAACCAAGTGGAAGG
AGCATTTGAGGCAGACGAAA

Product: PTS system, beta-glucoside-specific IIABC component

Products: NA

Alternate protein names: EIIBCA-Bgl; EII-Bgl; Beta-glucoside-specific phosphotransferase enzyme IIB component; PTS system beta-glucoside-specific EIIB component; Beta-glucoside permease IIC component; PTS system beta-glucoside-specific EIIC component; Beta-glucoside-specific phosphotransferase enzyme IIA component; PTS system beta-glucoside-specific EIIA component [H]

Number of amino acids: Translated: 620; Mature: 619

Protein sequence:

>620_residues
MTYQETAKAILAAVGGKTNIQRVTHCVTRLRLVLKNDEKVKDQQVKAISNVIGVMRKNGQYQIILGNDVNNYYQAFLSLG
HFDNQDEDHSSKAKGSILERLIETIAGVITPLIPALLGGGMLKVVGILLTMLGLASADSQTVAFINFFGDAAYYFMPVMI
AYSAAARFKVTPILAATIAGILLHPAFVAMVAEGKPLALFGAPVTPASYGSSVIPILMMVYLMQYIEKWVNRLVPSVMKS
FLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLAIYHVAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVL
ILPAMLASNLAQGAASLAVAFKTKQKQTRQVALAAGISALLAGITEPALYGVTLKFKKPLYAAMISGGLVGAFIGFVNIA
SYTFVVPSIIGLPQYINPSGGANFTNALIAGAATIVLAFSLTWFMGIDEESPEQVSVAVDMSQVKSGLSTKQTLYAPMTG
EMLFLSEVPDETFSSKLLGEGFAILPSEGVVYAPFDGEVITFFPTKHAVALKNTRGVEVLIHVGIDTVELKGQGFEQLVS
VGDVVKRGQALLKMDTDFITSKGYSLISPVVVTNSAEQLEIIIQDDKKMVTKEDALLVIL

Sequences:

>Translated_620_residues
MTYQETAKAILAAVGGKTNIQRVTHCVTRLRLVLKNDEKVKDQQVKAISNVIGVMRKNGQYQIILGNDVNNYYQAFLSLG
HFDNQDEDHSSKAKGSILERLIETIAGVITPLIPALLGGGMLKVVGILLTMLGLASADSQTVAFINFFGDAAYYFMPVMI
AYSAAARFKVTPILAATIAGILLHPAFVAMVAEGKPLALFGAPVTPASYGSSVIPILMMVYLMQYIEKWVNRLVPSVMKS
FLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLAIYHVAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVL
ILPAMLASNLAQGAASLAVAFKTKQKQTRQVALAAGISALLAGITEPALYGVTLKFKKPLYAAMISGGLVGAFIGFVNIA
SYTFVVPSIIGLPQYINPSGGANFTNALIAGAATIVLAFSLTWFMGIDEESPEQVSVAVDMSQVKSGLSTKQTLYAPMTG
EMLFLSEVPDETFSSKLLGEGFAILPSEGVVYAPFDGEVITFFPTKHAVALKNTRGVEVLIHVGIDTVELKGQGFEQLVS
VGDVVKRGQALLKMDTDFITSKGYSLISPVVVTNSAEQLEIIIQDDKKMVTKEDALLVIL
>Mature_619_residues
TYQETAKAILAAVGGKTNIQRVTHCVTRLRLVLKNDEKVKDQQVKAISNVIGVMRKNGQYQIILGNDVNNYYQAFLSLGH
FDNQDEDHSSKAKGSILERLIETIAGVITPLIPALLGGGMLKVVGILLTMLGLASADSQTVAFINFFGDAAYYFMPVMIA
YSAAARFKVTPILAATIAGILLHPAFVAMVAEGKPLALFGAPVTPASYGSSVIPILMMVYLMQYIEKWVNRLVPSVMKSF
LQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLAIYHVAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLI
LPAMLASNLAQGAASLAVAFKTKQKQTRQVALAAGISALLAGITEPALYGVTLKFKKPLYAAMISGGLVGAFIGFVNIAS
YTFVVPSIIGLPQYINPSGGANFTNALIAGAATIVLAFSLTWFMGIDEESPEQVSVAVDMSQVKSGLSTKQTLYAPMTGE
MLFLSEVPDETFSSKLLGEGFAILPSEGVVYAPFDGEVITFFPTKHAVALKNTRGVEVLIHVGIDTVELKGQGFEQLVSV
GDVVKRGQALLKMDTDFITSKGYSLISPVVVTNSAEQLEIIIQDDKKMVTKEDALLVIL

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790159, Length=636, Percent_Identity=33.9622641509434, Blast_Score=342, Evalue=6e-95,
Organism=Escherichia coli, GI48994906, Length=463, Percent_Identity=39.524838012959, Blast_Score=333, Evalue=2e-92,
Organism=Escherichia coli, GI2367362, Length=416, Percent_Identity=29.5673076923077, Blast_Score=185, Evalue=7e-48,
Organism=Escherichia coli, GI1786894, Length=146, Percent_Identity=39.7260273972603, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1788769, Length=439, Percent_Identity=27.3348519362187, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788757, Length=129, Percent_Identity=39.5348837209302, Blast_Score=108, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011297 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 66094; Mature: 65963

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYQETAKAILAAVGGKTNIQRVTHCVTRLRLVLKNDEKVKDQQVKAISNVIGVMRKNGQ
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
YQIILGNDVNNYYQAFLSLGHFDNQDEDHSSKAKGSILERLIETIAGVITPLIPALLGGG
EEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
MLKVVGILLTMLGLASADSQTVAFINFFGDAAYYFMPVMIAYSAAARFKVTPILAATIAG
HHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHH
ILLHPAFVAMVAEGKPLALFGAPVTPASYGSSVIPILMMVYLMQYIEKWVNRLVPSVMKS
HHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLAIYHVAPWLALAILGAIMPLVVMTG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MHWAFAPIFLAASVATPDVLILPAMLASNLAQGAASLAVAFKTKQKQTRQVALAAGISAL
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGITEPALYGVTLKFKKPLYAAMISGGLVGAFIGFVNIASYTFVVPSIIGLPQYINPSG
HHHCCCCHHEEEEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GANFTNALIAGAATIVLAFSLTWFMGIDEESPEQVSVAVDMSQVKSGLSTKQTLYAPMTG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHCCCCCCCEEECCCCC
EMLFLSEVPDETFSSKLLGEGFAILPSEGVVYAPFDGEVITFFPTKHAVALKNTRGVEVL
CEEEEECCCCHHHHHHHHCCCCEEECCCCEEECCCCCCEEEEECCCCEEEEECCCCEEEE
IHVGIDTVELKGQGFEQLVSVGDVVKRGQALLKMDTDFITSKGYSLISPVVVTNSAEQLE
EEECCCEEEECCCCHHHHHHHHHHHHHCCHHHHCCCHHHHCCCCHHHCCEEEECCHHHEE
IIIQDDKKMVTKEDALLVIL
EEEECCCHHHCCCCCEEEEC
>Mature Secondary Structure 
TYQETAKAILAAVGGKTNIQRVTHCVTRLRLVLKNDEKVKDQQVKAISNVIGVMRKNGQ
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
YQIILGNDVNNYYQAFLSLGHFDNQDEDHSSKAKGSILERLIETIAGVITPLIPALLGGG
EEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
MLKVVGILLTMLGLASADSQTVAFINFFGDAAYYFMPVMIAYSAAARFKVTPILAATIAG
HHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHH
ILLHPAFVAMVAEGKPLALFGAPVTPASYGSSVIPILMMVYLMQYIEKWVNRLVPSVMKS
HHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLAIYHVAPWLALAILGAIMPLVVMTG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MHWAFAPIFLAASVATPDVLILPAMLASNLAQGAASLAVAFKTKQKQTRQVALAAGISAL
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGITEPALYGVTLKFKKPLYAAMISGGLVGAFIGFVNIASYTFVVPSIIGLPQYINPSG
HHHCCCCHHEEEEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GANFTNALIAGAATIVLAFSLTWFMGIDEESPEQVSVAVDMSQVKSGLSTKQTLYAPMTG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHCCCCCCCEEECCCCC
EMLFLSEVPDETFSSKLLGEGFAILPSEGVVYAPFDGEVITFFPTKHAVALKNTRGVEVL
CEEEEECCCCHHHHHHHHCCCCEEECCCCEEECCCCCCEEEEECCCCEEEEECCCCEEEE
IHVGIDTVELKGQGFEQLVSVGDVVKRGQALLKMDTDFITSKGYSLISPVVVTNSAEQLE
EEECCCEEEECCCCHHHHHHHHHHHHHCCHHHHCCCHHHHCCCCHHHCCEEEECCHHHEE
IIIQDDKKMVTKEDALLVIL
EEEECCCHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7883710; 7704263; 9384377; 8628237 [H]