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The map label for this gene is licT [H]

Identifier: 94993892

GI number: 94993892

Start: 478615

End: 479457

Strand: Direct

Name: licT [H]

Synonym: MGAS10750_Spy0496

Alternate gene names: 94993892

Gene position: 478615-479457 (Clockwise)

Preceding gene: 94993890

Following gene: 94993893

Centisome position: 24.71

GC content: 35.71

Gene sequence:

>843_bases
ATGTTGATTAAACGCGTTTTAAACCATAATGCGGCGATTTCGACCAACCATCAAGGATTAGATATTTTATTGATGGGAAA
AGGGATTGCCTTTGGAAAAAAAGTTGGAGATAGTATTGAGCTTAATGCTATCGAAACATCATTTGTTTTAAAAAATAGTG
ACAATATGAATAGCTTCACAGAGTTATTTATTACGGTGCCACAAGAAGTTGTTGCTTGCTCAGAGAGAATTATCAATCTA
GGTAAAATTAAATTAGGCAAAACCTTAGATGAAATTCTCTATATTAATTTAACGGATCATATTCACTCTGCTATTGAAAG
GCATGAGCAAGGAATGTTGATTCATAACCCACTACGGTGGGAAATTCAACGCTATTATCCTGATGAATATAGTCTATGGG
TAAAAGCCTTAGAGCTAATTGAGCGTAATCTAGGAGTCACTCTAGCTATTGATGAAGCAGCTTTTATTGCCATGCATTTT
GTCAATGCTAGTTTGGACACTCCTTTTAAGGAGCCACATCGCCTGACGGAGATTGTTTCTTATATTGAGCAAAAAATCAA
AACAGACTTCAAAACAGAATTGGATGACACATCCATCGATTATTACCGCTTTATGACCCATATTAAATTATTTGCTCAAC
GTGTGTTATCCGAGATGTCTTACGATGATGATGATGCGGAACTGCTTTTAGTGGTGAAAACGAAATACCCTAAAGAATAC
CGGTGCGTCTTAGATATTAGTGAGGAGATAAAAAAGCGGTACAACTACCACCTTAATTCAAGCGAACTTTTGTATTTGAC
GGTTCATGTTAAACGTTTAGTGAAACATTTAAAGGAGACTTAA

Upstream 100 bases:

>100_bases
TTATCACAGTTTTGTGAGCAGGGACCTATTCGAAAAGTGCTTTTTAGCGAGCTTTTGGATAGGTCATTTTTTATTGTGAT
ACTAAAGGACTAGGACTTTT

Downstream 100 bases:

>100_bases
TATGACGTATCAAGAAACTGCCAAGGCTATTTTAGCGGCGGTTGGTGGCAAAACAAATATTCAACGTGTGACACACTGTG
TAACACGTCTACGCTTAGTA

Product: transcription antiterminator, BglG family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MLIKRVLNHNAAISTNHQGLDILLMGKGIAFGKKVGDSIELNAIETSFVLKNSDNMNSFTELFITVPQEVVACSERIINL
GKIKLGKTLDEILYINLTDHIHSAIERHEQGMLIHNPLRWEIQRYYPDEYSLWVKALELIERNLGVTLAIDEAAFIAMHF
VNASLDTPFKEPHRLTEIVSYIEQKIKTDFKTELDDTSIDYYRFMTHIKLFAQRVLSEMSYDDDDAELLLVVKTKYPKEY
RCVLDISEEIKKRYNYHLNSSELLYLTVHVKRLVKHLKET

Sequences:

>Translated_280_residues
MLIKRVLNHNAAISTNHQGLDILLMGKGIAFGKKVGDSIELNAIETSFVLKNSDNMNSFTELFITVPQEVVACSERIINL
GKIKLGKTLDEILYINLTDHIHSAIERHEQGMLIHNPLRWEIQRYYPDEYSLWVKALELIERNLGVTLAIDEAAFIAMHF
VNASLDTPFKEPHRLTEIVSYIEQKIKTDFKTELDDTSIDYYRFMTHIKLFAQRVLSEMSYDDDDAELLLVVKTKYPKEY
RCVLDISEEIKKRYNYHLNSSELLYLTVHVKRLVKHLKET
>Mature_280_residues
MLIKRVLNHNAAISTNHQGLDILLMGKGIAFGKKVGDSIELNAIETSFVLKNSDNMNSFTELFITVPQEVVACSERIINL
GKIKLGKTLDEILYINLTDHIHSAIERHEQGMLIHNPLRWEIQRYYPDEYSLWVKALELIERNLGVTLAIDEAAFIAMHF
VNASLDTPFKEPHRLTEIVSYIEQKIKTDFKTELDDTSIDYYRFMTHIKLFAQRVLSEMSYDDDDAELLLVVKTKYPKEY
RCVLDISEEIKKRYNYHLNSSELLYLTVHVKRLVKHLKET

Specific function: Mediates positive regulation of the glucanase operon (licST) by functioning as an antiterminator factor of transcription. Prevents termination at terminator lic-t [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PRD domains [H]

Homologues:

Organism=Escherichia coli, GI1790160, Length=275, Percent_Identity=36, Blast_Score=195, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004341
- InterPro:   IPR011608
- InterPro:   IPR001550 [H]

Pfam domain/function: PF03123 CAT_RBD; PF00874 PRD [H]

EC number: NA

Molecular weight: Translated: 32560; Mature: 32560

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00654 ANTITERMINATORS_BGLG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIKRVLNHNAAISTNHQGLDILLMGKGIAFGKKVGDSIELNAIETSFVLKNSDNMNSFT
CHHHHHHCCCCEEECCCCCEEEEEEECCCCCHHHCCCCEEEEEEEEEEEEECCCCCHHHH
ELFITVPQEVVACSERIINLGKIKLGKTLDEILYINLTDHIHSAIERHEQGMLIHNPLRW
HHHHCCCHHHHHHHHHHHHCCCEECCCCHHHHEEEEEHHHHHHHHHHHHCCCEEECCHHE
EIQRYYPDEYSLWVKALELIERNLGVTLAIDEAAFIAMHFVNASLDTPFKEPHRLTEIVS
EEHHHCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
YIEQKIKTDFKTELDDTSIDYYRFMTHIKLFAQRVLSEMSYDDDDAELLLVVKTKYPKEY
HHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCE
RCVLDISEEIKKRYNYHLNSSELLYLTVHVKRLVKHLKET
EEEEEHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MLIKRVLNHNAAISTNHQGLDILLMGKGIAFGKKVGDSIELNAIETSFVLKNSDNMNSFT
CHHHHHHCCCCEEECCCCCEEEEEEECCCCCHHHCCCCEEEEEEEEEEEEECCCCCHHHH
ELFITVPQEVVACSERIINLGKIKLGKTLDEILYINLTDHIHSAIERHEQGMLIHNPLRW
HHHHCCCHHHHHHHHHHHHCCCEECCCCHHHHEEEEEHHHHHHHHHHHHCCCEEECCHHE
EIQRYYPDEYSLWVKALELIERNLGVTLAIDEAAFIAMHFVNASLDTPFKEPHRLTEIVS
EEHHHCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
YIEQKIKTDFKTELDDTSIDYYRFMTHIKLFAQRVLSEMSYDDDDAELLLVVKTKYPKEY
HHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCE
RCVLDISEEIKKRYNYHLNSSELLYLTVHVKRLVKHLKET
EEEEEHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8606172; 8969509; 9384377; 6087283 [H]