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The map label for this gene is bglA [H]

Identifier: 94993894

GI number: 94993894

Start: 481340

End: 482764

Strand: Direct

Name: bglA [H]

Synonym: MGAS10750_Spy0498

Alternate gene names: 94993894

Gene position: 481340-482764 (Clockwise)

Preceding gene: 94993893

Following gene: 94993897

Centisome position: 24.85

GC content: 41.47

Gene sequence:

>1425_bases
ATGGGAATTTTTTCAAAAGATTTCTTATGGGGCGGCGCAGTAGCTGCCAACCAAGTGGAAGGAGCATTTGAGGCAGACGA
AAAAGGTTTGTCCGTACAAGATGTTCTACCAAATGGTGGACTAGGAGAATGGACAGATAGTCCTACCAGCGATAATTTAA
CTTTAGAGGCGATTGATTTTTACCACCGCTACAAAGAAGACATTGCTCTTTTTGCCGAGATGGGCTTTAAAGTCTTTCGA
ACGTCTATTGCTTGGTCTCGTATTTTTCCAAATGGTGACGATGACCAGCCCAATGAAGCAGGTTTGCAATTTTATGATGA
CTTATTCGATGAATTGTTGAACTATGGTATCGAACCCTTAGTGACCTTGTCGCATTATGAGACACCTCTGCATTTGGCCA
AAGCCTATAATGGTTGGACAGATAGACGTCTGATTGGCTTTTTTGAGCGCTTTGCTCAGACAGTCATGGAACGCTATAAG
GACAAAGTCAAATACTGGTTGACCTTCAACGAAGTCAACTCGATTTTACACATGCCCTTTACCAGTGGTGGCATCATGAC
AGAAAAAGAAAAGCTGAGCCTGCAAGATTTATACCAAGCTATTCATCATGAATTGGTAGCATCTGCTAGTGTCACAAAGC
TAGCGCATGAAATCAATCCTGATGTTAAAGTTGGGTGTATGATTTTGGCGATGCCTGCTTACCCAATGACCTCTGATCCT
CGTGATATACTTGCTGCGCATGCATTTGAAAATCTTAATCTCTTATTTTCAGATATTCATGTGAGAGGCAAGTATCCTTC
ATATATTAAGTCGTATTTTAAAGAAAATGGGATTGAGATTGTTTTTGAAGACGGAGACAAGGAATTATTAGCGGAACATA
CGGTTGATTTTCTATCCTTTAGCTATTACATGAGTGTCACACAAGCCCACAATCCTGAAGCTTACACATCTGGTCAGGGA
AATATTCTAGGTGGTTTGTCCAATCCATATTTAGAATCTTCGGAGTGGGGTTGGCAGATAGACCCAATTGGTCTGCGATT
GGTCTTGAATCAGTACTATGACCGCTACCAGATTCCTTTGTTTATTGTTGAAAATGGCTTAGGTGCAAAGGATCAGCTGG
TGCAAACCGCAGATGGCAGCATGACGGTTCACGATGATTATCGCATTGACTACATGAGTCAGCATCTCGTACAAGTTGCC
AAAGCGATTGAAGATGGCGTTGAGGTCATGGGTTACACTGCTTGGGGCTGTATTGATTGTGTCTCTATGTCAACAGCCCA
ATTAAGTAAGCGCTACGGTTTTATTTATGTTGACCGAAATGATGATGGTACTGGTCAACTCACACGCTATAAGAAAAAAT
CATTTGATTGGTACCGACAAGTCATTCAAACCAATGGACGTTACCTTGAGGATAATTTTTCCTAA

Upstream 100 bases:

>100_bases
TTCGGCTGAGCAGTTGGAGATTATTATTCAAGATGACAAAAAAATGGTGACTAAAGAGGACGCTTTGTTAGTCATTTTAT
AACCTAAAAGGAGAGGGAGA

Downstream 100 bases:

>100_bases
ATAGGTCTTGTTTAAGATGGTGACTCTGTTCCTATGCTAACTGATAAAACTCAAAAAGCATTTGTTTTGATAAAAAACAA
GTGCTTTTTTATTAGTCTTT

Product: 6-phospho-beta-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MGIFSKDFLWGGAVAANQVEGAFEADEKGLSVQDVLPNGGLGEWTDSPTSDNLTLEAIDFYHRYKEDIALFAEMGFKVFR
TSIAWSRIFPNGDDDQPNEAGLQFYDDLFDELLNYGIEPLVTLSHYETPLHLAKAYNGWTDRRLIGFFERFAQTVMERYK
DKVKYWLTFNEVNSILHMPFTSGGIMTEKEKLSLQDLYQAIHHELVASASVTKLAHEINPDVKVGCMILAMPAYPMTSDP
RDILAAHAFENLNLLFSDIHVRGKYPSYIKSYFKENGIEIVFEDGDKELLAEHTVDFLSFSYYMSVTQAHNPEAYTSGQG
NILGGLSNPYLESSEWGWQIDPIGLRLVLNQYYDRYQIPLFIVENGLGAKDQLVQTADGSMTVHDDYRIDYMSQHLVQVA
KAIEDGVEVMGYTAWGCIDCVSMSTAQLSKRYGFIYVDRNDDGTGQLTRYKKKSFDWYRQVIQTNGRYLEDNFS

Sequences:

>Translated_474_residues
MGIFSKDFLWGGAVAANQVEGAFEADEKGLSVQDVLPNGGLGEWTDSPTSDNLTLEAIDFYHRYKEDIALFAEMGFKVFR
TSIAWSRIFPNGDDDQPNEAGLQFYDDLFDELLNYGIEPLVTLSHYETPLHLAKAYNGWTDRRLIGFFERFAQTVMERYK
DKVKYWLTFNEVNSILHMPFTSGGIMTEKEKLSLQDLYQAIHHELVASASVTKLAHEINPDVKVGCMILAMPAYPMTSDP
RDILAAHAFENLNLLFSDIHVRGKYPSYIKSYFKENGIEIVFEDGDKELLAEHTVDFLSFSYYMSVTQAHNPEAYTSGQG
NILGGLSNPYLESSEWGWQIDPIGLRLVLNQYYDRYQIPLFIVENGLGAKDQLVQTADGSMTVHDDYRIDYMSQHLVQVA
KAIEDGVEVMGYTAWGCIDCVSMSTAQLSKRYGFIYVDRNDDGTGQLTRYKKKSFDWYRQVIQTNGRYLEDNFS
>Mature_473_residues
GIFSKDFLWGGAVAANQVEGAFEADEKGLSVQDVLPNGGLGEWTDSPTSDNLTLEAIDFYHRYKEDIALFAEMGFKVFRT
SIAWSRIFPNGDDDQPNEAGLQFYDDLFDELLNYGIEPLVTLSHYETPLHLAKAYNGWTDRRLIGFFERFAQTVMERYKD
KVKYWLTFNEVNSILHMPFTSGGIMTEKEKLSLQDLYQAIHHELVASASVTKLAHEINPDVKVGCMILAMPAYPMTSDPR
DILAAHAFENLNLLFSDIHVRGKYPSYIKSYFKENGIEIVFEDGDKELLAEHTVDFLSFSYYMSVTQAHNPEAYTSGQGN
ILGGLSNPYLESSEWGWQIDPIGLRLVLNQYYDRYQIPLFIVENGLGAKDQLVQTADGSMTVHDDYRIDYMSQHLVQVAK
AIEDGVEVMGYTAWGCIDCVSMSTAQLSKRYGFIYVDRNDDGTGQLTRYKKKSFDWYRQVIQTNGRYLEDNFS

Specific function: Can Hydrolyze Salicin And Arbutin. [C]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=491, Percent_Identity=31.5682281059063, Blast_Score=202, Evalue=5e-52,
Organism=Homo sapiens, GI32481206, Length=485, Percent_Identity=27.2164948453608, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI13273313, Length=484, Percent_Identity=26.6528925619835, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI28376633, Length=486, Percent_Identity=27.9835390946502, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI24497614, Length=486, Percent_Identity=26.1316872427983, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI2367270, Length=471, Percent_Identity=55.2016985138004, Blast_Score=527, Evalue=1e-151,
Organism=Escherichia coli, GI1789070, Length=479, Percent_Identity=51.5657620041754, Blast_Score=513, Evalue=1e-147,
Organism=Escherichia coli, GI2367174, Length=480, Percent_Identity=52.7083333333333, Blast_Score=506, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI17552856, Length=483, Percent_Identity=29.6066252587992, Blast_Score=160, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI17539390, Length=500, Percent_Identity=28.6, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21356577, Length=499, Percent_Identity=28.4569138276553, Blast_Score=160, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 53994; Mature: 53863

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIFSKDFLWGGAVAANQVEGAFEADEKGLSVQDVLPNGGLGEWTDSPTSDNLTLEAIDF
CCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEHHHHH
YHRYKEDIALFAEMGFKVFRTSIAWSRIFPNGDDDQPNEAGLQFYDDLFDELLNYGIEPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCE
VTLSHYETPLHLAKAYNGWTDRRLIGFFERFAQTVMERYKDKVKYWLTFNEVNSILHMPF
EEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHCCEEECCC
TSGGIMTEKEKLSLQDLYQAIHHELVASASVTKLAHEINPDVKVGCMILAMPAYPMTSDP
CCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCH
RDILAAHAFENLNLLFSDIHVRGKYPSYIKSYFKENGIEIVFEDGDKELLAEHTVDFLSF
HHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHH
SYYMSVTQAHNPEAYTSGQGNILGGLSNPYLESSEWGWQIDPIGLRLVLNQYYDRYQIPL
HHHHHHHHCCCCCCEECCCCCEECCCCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCEE
FIVENGLGAKDQLVQTADGSMTVHDDYRIDYMSQHLVQVAKAIEDGVEVMGYTAWGCIDC
EEEECCCCCHHHHHEECCCCEEEECCCCHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHH
VSMSTAQLSKRYGFIYVDRNDDGTGQLTRYKKKSFDWYRQVIQTNGRYLEDNFS
HHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCC
>Mature Secondary Structure 
GIFSKDFLWGGAVAANQVEGAFEADEKGLSVQDVLPNGGLGEWTDSPTSDNLTLEAIDF
CCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEHHHHH
YHRYKEDIALFAEMGFKVFRTSIAWSRIFPNGDDDQPNEAGLQFYDDLFDELLNYGIEPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCE
VTLSHYETPLHLAKAYNGWTDRRLIGFFERFAQTVMERYKDKVKYWLTFNEVNSILHMPF
EEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHCCEEECCC
TSGGIMTEKEKLSLQDLYQAIHHELVASASVTKLAHEINPDVKVGCMILAMPAYPMTSDP
CCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCH
RDILAAHAFENLNLLFSDIHVRGKYPSYIKSYFKENGIEIVFEDGDKELLAEHTVDFLSF
HHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHH
SYYMSVTQAHNPEAYTSGQGNILGGLSNPYLESSEWGWQIDPIGLRLVLNQYYDRYQIPL
HHHHHHHHCCCCCCEECCCCCEECCCCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCEE
FIVENGLGAKDQLVQTADGSMTVHDDYRIDYMSQHLVQVAKAIEDGVEVMGYTAWGCIDC
EEEECCCCCHHHHHEECCCCEEEECCCCHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHH
VSMSTAQLSKRYGFIYVDRNDDGTGQLTRYKKKSFDWYRQVIQTNGRYLEDNFS
HHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA