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The map label for this gene is pgl [H]

Identifier: 94314719

GI number: 94314719

Start: 2557979

End: 2558659

Strand: Reverse

Name: pgl [H]

Synonym: Rmet_5800

Alternate gene names: 94314719

Gene position: 2558659-2557979 (Counterclockwise)

Preceding gene: 94314720

Following gene: 94314718

Centisome position: 99.17

GC content: 66.81

Gene sequence:

>681_bases
ATGCGCCAATTCGAACATGCGACGTTGATGGACCAGGCTGAATCACTGGCCATCTCGATCGGTCACGCGCTTGATCTCGC
GATCAAGGCCAAAGGCTGGGCCGTGCTGGCCGTGTCGGGCGGCAAGTCGCCACAAGCCATGTTCGAACGACTGCGCTACC
GCCCCGTTCGCTGGGAAGCCGTGACGGTCACGCTGGTCGACGAGCGCGCGGTGCCGCCCGATGACGCCGACAGCAACGGA
GCCATGGTGCGCAGCCACTTGCTGCGCGAAGGCGCGGGCGTGGCGGCCTGGGCGCCGTTGATCCGCGATGAGGCCGAGGC
CGCGCATCCGCAAAGCGCGGTGGCGCGCCTGAATCAGGCCTTCCTGCAACCGGATGTAGTAGTGCTGGGCATGGGCGAAG
ATGGTCACACGGCCTCGCTGTTTCCGGATGCGCCTGAGCTTCAGACCGCCCTGTCCGAACCGACTCCGGGCTATATCGTT
ACCCATCCGTCCGTCGCGCCCCATGCGCGCGTCACGCTGAACCTGGCCGCGTTGCTGGCGGCGGACCGCATGTTCCTGGC
AATCAGCGGCGAGAAGAAGGCCGCCGTGCTGGAGCAGGCGCTGAAGACGCCGACGCCCTCGTTGCCGGTCAGTGTCGTGC
TGGCACGGCACCGCCACGGCGTCGATGTCTTCCGGGTCTAA

Upstream 100 bases:

>100_bases
ATGGCATGAGGAGGCCTGACGCGCCACCGAAGGATCGGAGACATCGGAAACATCGGATTCACCACGACACGAGAACCATA
AGGAGTAGAAGGAGCAGCCC

Downstream 100 bases:

>100_bases
GCCGATGACGGATCGCGCGATGTCCTATCCCCGGATCCTGGCCGACGTGGGCGGCACCAACGTGCGCTTTGCCATGGAGA
CGGCGCCGATGCGGATCGGC

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MRQFEHATLMDQAESLAISIGHALDLAIKAKGWAVLAVSGGKSPQAMFERLRYRPVRWEAVTVTLVDERAVPPDDADSNG
AMVRSHLLREGAGVAAWAPLIRDEAEAAHPQSAVARLNQAFLQPDVVVLGMGEDGHTASLFPDAPELQTALSEPTPGYIV
THPSVAPHARVTLNLAALLAADRMFLAISGEKKAAVLEQALKTPTPSLPVSVVLARHRHGVDVFRV

Sequences:

>Translated_226_residues
MRQFEHATLMDQAESLAISIGHALDLAIKAKGWAVLAVSGGKSPQAMFERLRYRPVRWEAVTVTLVDERAVPPDDADSNG
AMVRSHLLREGAGVAAWAPLIRDEAEAAHPQSAVARLNQAFLQPDVVVLGMGEDGHTASLFPDAPELQTALSEPTPGYIV
THPSVAPHARVTLNLAALLAADRMFLAISGEKKAAVLEQALKTPTPSLPVSVVLARHRHGVDVFRV
>Mature_226_residues
MRQFEHATLMDQAESLAISIGHALDLAIKAKGWAVLAVSGGKSPQAMFERLRYRPVRWEAVTVTLVDERAVPPDDADSNG
AMVRSHLLREGAGVAAWAPLIRDEAEAAHPQSAVARLNQAFLQPDVVVLGMGEDGHTASLFPDAPELQTALSEPTPGYIV
THPSVAPHARVTLNLAALLAADRMFLAISGEKKAAVLEQALKTPTPSLPVSVVLARHRHGVDVFRV

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=184, Percent_Identity=33.695652173913, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI6912586, Length=159, Percent_Identity=36.4779874213836, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321687, Length=195, Percent_Identity=27.1794871794872, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321957, Length=229, Percent_Identity=29.6943231441048, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 24203; Mature: 24203

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQFEHATLMDQAESLAISIGHALDLAIKAKGWAVLAVSGGKSPQAMFERLRYRPVRWEA
CCCCCHHHHHHHHHHHEEEECCEEEEEEEECCEEEEEEECCCCHHHHHHHHHCCCCEEEE
VTVTLVDERAVPPDDADSNGAMVRSHLLREGAGVAAWAPLIRDEAEAAHPQSAVARLNQA
EEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
FLQPDVVVLGMGEDGHTASLFPDAPELQTALSEPTPGYIVTHPSVAPHARVTLNLAALLA
HCCCCEEEEEECCCCCEEECCCCCHHHHHHHCCCCCCEEEECCCCCCCCEEHHHHHHHHH
ADRMFLAISGEKKAAVLEQALKTPTPSLPVSVVLARHRHGVDVFRV
HCEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEECC
>Mature Secondary Structure
MRQFEHATLMDQAESLAISIGHALDLAIKAKGWAVLAVSGGKSPQAMFERLRYRPVRWEA
CCCCCHHHHHHHHHHHEEEECCEEEEEEEECCEEEEEEECCCCHHHHHHHHHCCCCEEEE
VTVTLVDERAVPPDDADSNGAMVRSHLLREGAGVAAWAPLIRDEAEAAHPQSAVARLNQA
EEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
FLQPDVVVLGMGEDGHTASLFPDAPELQTALSEPTPGYIVTHPSVAPHARVTLNLAALLA
HCCCCEEEEEECCCCCEEECCCCCHHHHHHHCCCCCCEEEECCCCCCCCEEHHHHHHHHH
ADRMFLAISGEKKAAVLEQALKTPTPSLPVSVVLARHRHGVDVFRV
HCEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]