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The map label for this gene is glk

Identifier: 94314718

GI number: 94314718

Start: 2556964

End: 2557974

Strand: Reverse

Name: glk

Synonym: Rmet_5799

Alternate gene names: 94314718

Gene position: 2557974-2556964 (Counterclockwise)

Preceding gene: 94314719

Following gene: 94314717

Centisome position: 99.14

GC content: 69.34

Gene sequence:

>1011_bases
ATGACGGATCGCGCGATGTCCTATCCCCGGATCCTGGCCGACGTGGGCGGCACCAACGTGCGCTTTGCCATGGAGACGGC
GCCGATGCGGATCGGCGAGATCACCGCATACAAGGTGGCCGAGCACGCCTCGCTCGAAGCCGCGATGCGGCTCTACATGC
TGACGCGTAGCGGCGCGGCCCGGCCGCGCCATGCGGCCATCGGCCTGGCCAATCCGGTCACTGGTGACCAGGTCAAGCTG
ACCAACCACAACTGGGCGTTCTCCGTCGAGGCCATGCGCCGCGCGCTCGATCTCGACACGCTGGTGGCCATCAACGACTT
CACCTCGCTGGCGCTGGCGCTGCCGTATCTGCCCGACGCCAGCCTTGTGCAGGTACGCGACGGCACGGCGGTGGCCACGG
CGCCCCGGGCCTTGATCGGGCCGGGAACCGGCCTTGGCGTATCCGGCCTGATTCCCGCGCCGGGTGGCGCGGTGGCGCTG
GCGGGCGAGGGCGGACACATCGAGATCATGCCGGTCACCGACGACGAGTGGATCGCCTGGCGCGCCGCCCACGATCAGTT
TGGGCGCGTGTCGGCGGAGCGGCTGCTGTCGGGTATGGGTCTCTCGCATATTCATGCCGCGCTGTCCGCAGAAATGGGTA
CGCCTCTGGAGGTGCCGCTGGCACCGGCGCAGGTGACGGACGGCGCGATGCGCGCGGGCGACCCGGTATGCCGCCGCGCT
TTCGACGCGTTCTGCGGGATGCTCGGCTCGGTTGCCGCCGATGTCGCGCTGGTGCTCGGCGCACGTGGTGGCGTCTATCT
CGGCGGTGGTATCGTTCCACGCTTTGTCGATGCCCTACGGGCGTCGACGTTCGCGGAGCGCTTTGTCGCCAAGGGCCGCA
TGGGCAGTTTCCTTGCCGATGTGCCGGTGTACGTGATCACGGCCGAGTATCCGGCGCTGCCGGGCCTGGCTCGCGCACTG
GCGGATCGGCTTGAAGCCGACGCGCGCCGCGCCGAGACCTCTCAATCCTGA

Upstream 100 bases:

>100_bases
GTGCTGGAGCAGGCGCTGAAGACGCCGACGCCCTCGTTGCCGGTCAGTGTCGTGCTGGCACGGCACCGCCACGGCGTCGA
TGTCTTCCGGGTCTAAGCCG

Downstream 100 bases:

>100_bases
AAGACGATGCGTGTATTGCTGGTAGAAGATGACGCCATGATCGGCGAAAGCGTGAAGGTGGCGCTGCGCCAGGAGGGTTT
TACGGTCGACTGGGTGCGCG

Product: Glucokinase

Products: NA

Alternate protein names: Glucose kinase

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTDRAMSYPRILADVGGTNVRFAMETAPMRIGEITAYKVAEHASLEAAMRLYMLTRSGAARPRHAAIGLANPVTGDQVKL
TNHNWAFSVEAMRRALDLDTLVAINDFTSLALALPYLPDASLVQVRDGTAVATAPRALIGPGTGLGVSGLIPAPGGAVAL
AGEGGHIEIMPVTDDEWIAWRAAHDQFGRVSAERLLSGMGLSHIHAALSAEMGTPLEVPLAPAQVTDGAMRAGDPVCRRA
FDAFCGMLGSVAADVALVLGARGGVYLGGGIVPRFVDALRASTFAERFVAKGRMGSFLADVPVYVITAEYPALPGLARAL
ADRLEADARRAETSQS

Sequences:

>Translated_336_residues
MTDRAMSYPRILADVGGTNVRFAMETAPMRIGEITAYKVAEHASLEAAMRLYMLTRSGAARPRHAAIGLANPVTGDQVKL
TNHNWAFSVEAMRRALDLDTLVAINDFTSLALALPYLPDASLVQVRDGTAVATAPRALIGPGTGLGVSGLIPAPGGAVAL
AGEGGHIEIMPVTDDEWIAWRAAHDQFGRVSAERLLSGMGLSHIHAALSAEMGTPLEVPLAPAQVTDGAMRAGDPVCRRA
FDAFCGMLGSVAADVALVLGARGGVYLGGGIVPRFVDALRASTFAERFVAKGRMGSFLADVPVYVITAEYPALPGLARAL
ADRLEADARRAETSQS
>Mature_335_residues
TDRAMSYPRILADVGGTNVRFAMETAPMRIGEITAYKVAEHASLEAAMRLYMLTRSGAARPRHAAIGLANPVTGDQVKLT
NHNWAFSVEAMRRALDLDTLVAINDFTSLALALPYLPDASLVQVRDGTAVATAPRALIGPGTGLGVSGLIPAPGGAVALA
GEGGHIEIMPVTDDEWIAWRAAHDQFGRVSAERLLSGMGLSHIHAALSAEMGTPLEVPLAPAQVTDGAMRAGDPVCRRAF
DAFCGMLGSVAADVALVLGARGGVYLGGGIVPRFVDALRASTFAERFVAKGRMGSFLADVPVYVITAEYPALPGLARALA
DRLEADARRAETSQS

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family

Homologues:

Organism=Escherichia coli, GI1788732, Length=311, Percent_Identity=38.2636655948553, Blast_Score=215, Evalue=4e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLK_RALME (Q1LB18)

Other databases:

- EMBL:   CP000353
- RefSeq:   YP_587927.1
- ProteinModelPortal:   Q1LB18
- STRING:   Q1LB18
- GeneID:   4042663
- GenomeReviews:   CP000353_GR
- KEGG:   rme:Rmet_5799
- eggNOG:   COG0837
- HOGENOM:   HBG644410
- OMA:   VDIGGTH
- PhylomeDB:   Q1LB18
- ProtClustDB:   CLSK769004
- BioCyc:   RMET266264:RMET_5799-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00524
- InterPro:   IPR003836
- TIGRFAMs:   TIGR00749

Pfam domain/function: PF02685 Glucokinase

EC number: =2.7.1.2

Molecular weight: Translated: 35186; Mature: 35055

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRAMSYPRILADVGGTNVRFAMETAPMRIGEITAYKVAEHASLEAAMRLYMLTRSGAA
CCCCHHCCCHHHHHCCCCCEEEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCC
RPRHAAIGLANPVTGDQVKLTNHNWAFSVEAMRRALDLDTLVAINDFTSLALALPYLPDA
CCCHHEEECCCCCCCCEEEEECCCEEEEHHHHHHHHCHHHEEEHHHHHHHHHHHCCCCCC
SLVQVRDGTAVATAPRALIGPGTGLGVSGLIPAPGGAVALAGEGGHIEIMPVTDDEWIAW
CEEEEECCCEEECCCCCEECCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCEEEE
RAAHDQFGRVSAERLLSGMGLSHIHAALSAEMGTPLEVPLAPAQVTDGAMRAGDPVCRRA
EECHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHCCCHHHHHH
FDAFCGMLGSVAADVALVLGARGGVYLGGGIVPRFVDALRASTFAERFVAKGRMGSFLAD
HHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHC
VPVYVITAEYPALPGLARALADRLEADARRAETSQS
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDRAMSYPRILADVGGTNVRFAMETAPMRIGEITAYKVAEHASLEAAMRLYMLTRSGAA
CCCHHCCCHHHHHCCCCCEEEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCC
RPRHAAIGLANPVTGDQVKLTNHNWAFSVEAMRRALDLDTLVAINDFTSLALALPYLPDA
CCCHHEEECCCCCCCCEEEEECCCEEEEHHHHHHHHCHHHEEEHHHHHHHHHHHCCCCCC
SLVQVRDGTAVATAPRALIGPGTGLGVSGLIPAPGGAVALAGEGGHIEIMPVTDDEWIAW
CEEEEECCCEEECCCCCEECCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCEEEE
RAAHDQFGRVSAERLLSGMGLSHIHAALSAEMGTPLEVPLAPAQVTDGAMRAGDPVCRRA
EECHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHCCCHHHHHH
FDAFCGMLGSVAADVALVLGARGGVYLGGGIVPRFVDALRASTFAERFVAKGRMGSFLAD
HHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHC
VPVYVITAEYPALPGLARALADRLEADARRAETSQS
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA