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The map label for this gene is ygcU [H]

Identifier: 94314362

GI number: 94314362

Start: 2191850

End: 2193403

Strand: Reverse

Name: ygcU [H]

Synonym: Rmet_5443

Alternate gene names: 94314362

Gene position: 2193403-2191850 (Counterclockwise)

Preceding gene: 94314363

Following gene: 94314361

Centisome position: 85.01

GC content: 64.99

Gene sequence:

>1554_bases
ATGATCAGCAAGGAAGCCATCAAGCGCGGCTACAACCGTGGCAACTACGTCGTCGGCAAGCACACGCCGCCTCACTTTGC
CGGGAGTATCACGGCGACGCCAGACGCGCCGGGCCTGCAGCGGGATGCCGTCGCGATCGACAACGACACGCTCGACGCGT
TGCGCAAGGCCGCCGATCACGTTCTGACCGCCACCAGTGACGTGGTTGAGTGGACGCGCGACTGGTGGGCTGGCTCGATG
ATGACCGAGACGGGCGGCAAGCCCGCCACGCCGCGTGGCGTGATCGTGCGTGTCTCCACGATCGAGCAGATTCAGGCAGT
GATGCGCATTGCGCACGCCAAAGCCATTCCCGTGACCGTATCGGCCGGCCGCAGCAACGTGACTGGCGCGGCGCTGCCCG
TGCGCGGTGGCATCGTGCTCGATGTGTGCGATGTGAACAGGCTGCTGGGCTTCGACCGCGAGAGCCAGATCGTCGAAGTG
GAGTCGGGCATGTTCGGCGATATCTTCGAGCAGACGATTCAGCAGGAGTACGGCATGACGATGGGCCACTGGCCGTCGTC
GTACGCGATCAGCACGGTCGGCGGCTGGGTGGCATGCCGCGGCGCAGGCCAGCTTTCCACGCGCTACGGCAAGATCGAGG
ACATGGTGGTCGGCATGGACGTGGTGCTGGCCGACGGCAGCCTGGTGACCGTGGGAGGCTATCCCCGCGCCGCGCTGGGC
CCGGACCTGATGCAGGTGTTTATCGGATCGGAAGGCACGCTCGGGGTAATCGTGCGCGTGCGCCTGAAGCTGCATCGGCT
GCCCGACTATGGTCGCGCTATTGCCTACGGCTTCAAGACCTTCGCGATCGGCCTCGACGCGTGCCGCGAGATCATGCAAC
GTGGCGCGAATCCCGCCGCGCTGCGTCTCTACGACGAACTCGAAAGTGGCGTGCAGTTCGGCCTGCCCGAGACCAATGTG
CTGCTGGTGGCCGATGAAGGCACAAAGGAAATGGTTGACGCCGTGATGGCGATCAGCGAGCGTGTCTGCGCCGAACTTGG
TGACAGGCTCGATGGTGACGCGATCTTCGAGCGCTGGCTCGACACGCGTTACCTGACTGGCAAGAGTGCCGAAGGCTTCA
AGCGCAGCCCCGGCTTCGTGGCCGACACGCTAGAGATGGCCGGCCCGTGGAGCGATCTGGCCGCGATCTACACCGACGTG
GTGGCGGCGATCAACGCGGTGCCCGGCACGCTGGCGGGTTCCGCGCACCAGTCGCATGCCTATGTGGATGGCGCGTGCCT
GTATTTTTCGTTGCGCGGTGACGTGGCCGTGGGAGATCGCCAGAAGTGGTATCGCGCGGCATGGGATGCGGCCAACGCGG
TGCTCATCCAATACAATGCGGCGCTGAGCCACCATCACGGCATCGGTCTGCTGCGCGCGCCCTACATGGCGCCGTCGCTC
GACACGGCGTTCCCGGTGCTGGTGGCAGTGAAGCGGGCACTTGATCCGCAAAACATCCTCAATCCGGGCAAGCTCGGCCT
TTCGGACGTGCTGCCCCACGAAGTGAAGAAGTAA

Upstream 100 bases:

>100_bases
AGGCCGAGCTCGGACTTTCCGGGCAGGCCGTCGCGCAGCAGGTCAGTGACTACCTGGCCGCTGTCGCCCTCGAAAAATCC
GTCCTAATGGGAGAAGCAAC

Downstream 100 bases:

>100_bases
GCCATGGACAGGTCTCTCGGCGCCCGCCTGACACGACACCCTGTAATCGCCACGCTGTACGGCGCGGACCAGATCGATGC
CTTCATCGACAGCGAGGCGG

Product: putative alkylglycerone-phosphate synthase

Products: alkyl-glycerone 3-phosphate; long-chain acid anion

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MISKEAIKRGYNRGNYVVGKHTPPHFAGSITATPDAPGLQRDAVAIDNDTLDALRKAADHVLTATSDVVEWTRDWWAGSM
MTETGGKPATPRGVIVRVSTIEQIQAVMRIAHAKAIPVTVSAGRSNVTGAALPVRGGIVLDVCDVNRLLGFDRESQIVEV
ESGMFGDIFEQTIQQEYGMTMGHWPSSYAISTVGGWVACRGAGQLSTRYGKIEDMVVGMDVVLADGSLVTVGGYPRAALG
PDLMQVFIGSEGTLGVIVRVRLKLHRLPDYGRAIAYGFKTFAIGLDACREIMQRGANPAALRLYDELESGVQFGLPETNV
LLVADEGTKEMVDAVMAISERVCAELGDRLDGDAIFERWLDTRYLTGKSAEGFKRSPGFVADTLEMAGPWSDLAAIYTDV
VAAINAVPGTLAGSAHQSHAYVDGACLYFSLRGDVAVGDRQKWYRAAWDAANAVLIQYNAALSHHHGIGLLRAPYMAPSL
DTAFPVLVAVKRALDPQNILNPGKLGLSDVLPHEVKK

Sequences:

>Translated_517_residues
MISKEAIKRGYNRGNYVVGKHTPPHFAGSITATPDAPGLQRDAVAIDNDTLDALRKAADHVLTATSDVVEWTRDWWAGSM
MTETGGKPATPRGVIVRVSTIEQIQAVMRIAHAKAIPVTVSAGRSNVTGAALPVRGGIVLDVCDVNRLLGFDRESQIVEV
ESGMFGDIFEQTIQQEYGMTMGHWPSSYAISTVGGWVACRGAGQLSTRYGKIEDMVVGMDVVLADGSLVTVGGYPRAALG
PDLMQVFIGSEGTLGVIVRVRLKLHRLPDYGRAIAYGFKTFAIGLDACREIMQRGANPAALRLYDELESGVQFGLPETNV
LLVADEGTKEMVDAVMAISERVCAELGDRLDGDAIFERWLDTRYLTGKSAEGFKRSPGFVADTLEMAGPWSDLAAIYTDV
VAAINAVPGTLAGSAHQSHAYVDGACLYFSLRGDVAVGDRQKWYRAAWDAANAVLIQYNAALSHHHGIGLLRAPYMAPSL
DTAFPVLVAVKRALDPQNILNPGKLGLSDVLPHEVKK
>Mature_517_residues
MISKEAIKRGYNRGNYVVGKHTPPHFAGSITATPDAPGLQRDAVAIDNDTLDALRKAADHVLTATSDVVEWTRDWWAGSM
MTETGGKPATPRGVIVRVSTIEQIQAVMRIAHAKAIPVTVSAGRSNVTGAALPVRGGIVLDVCDVNRLLGFDRESQIVEV
ESGMFGDIFEQTIQQEYGMTMGHWPSSYAISTVGGWVACRGAGQLSTRYGKIEDMVVGMDVVLADGSLVTVGGYPRAALG
PDLMQVFIGSEGTLGVIVRVRLKLHRLPDYGRAIAYGFKTFAIGLDACREIMQRGANPAALRLYDELESGVQFGLPETNV
LLVADEGTKEMVDAVMAISERVCAELGDRLDGDAIFERWLDTRYLTGKSAEGFKRSPGFVADTLEMAGPWSDLAAIYTDV
VAAINAVPGTLAGSAHQSHAYVDGACLYFSLRGDVAVGDRQKWYRAAWDAANAVLIQYNAALSHHHGIGLLRAPYMAPSL
DTAFPVLVAVKRALDPQNILNPGKLGLSDVLPHEVKK

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI4501993, Length=428, Percent_Identity=28.7383177570093, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI37595756, Length=430, Percent_Identity=21.8604651162791, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI119964728, Length=201, Percent_Identity=29.8507462686567, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI37595754, Length=453, Percent_Identity=20.9713024282561, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI48994907, Length=432, Percent_Identity=29.3981481481481, Blast_Score=169, Evalue=5e-43,
Organism=Escherichia coli, GI1789351, Length=429, Percent_Identity=24.009324009324, Blast_Score=89, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17556096, Length=517, Percent_Identity=25.1450676982592, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71992373, Length=440, Percent_Identity=24.3181818181818, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71992381, Length=440, Percent_Identity=24.5454545454545, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71992392, Length=338, Percent_Identity=25.7396449704142, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17534361, Length=495, Percent_Identity=22.2222222222222, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320027, Length=519, Percent_Identity=25.0481695568401, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320764, Length=524, Percent_Identity=23.0916030534351, Blast_Score=87, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6320023, Length=241, Percent_Identity=23.6514522821577, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24653753, Length=445, Percent_Identity=30.3370786516854, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI18921117, Length=441, Percent_Identity=23.5827664399093, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24639277, Length=441, Percent_Identity=23.5827664399093, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24639275, Length=441, Percent_Identity=23.5827664399093, Blast_Score=96, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: 2.5.1.26

Molecular weight: Translated: 55564; Mature: 55564

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISKEAIKRGYNRGNYVVGKHTPPHFAGSITATPDAPGLQRDAVAIDNDTLDALRKAADH
CCCHHHHHCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCCEEECCHHHHHHHHHHHH
VLTATSDVVEWTRDWWAGSMMTETGGKPATPRGVIVRVSTIEQIQAVMRIAHAKAIPVTV
HHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCEEEE
SAGRSNVTGAALPVRGGIVLDVCDVNRLLGFDRESQIVEVESGMFGDIFEQTIQQEYGMT
ECCCCCCCCCEEEECCCEEEEEECCHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCE
MGHWPSSYAISTVGGWVACRGAGQLSTRYGKIEDMVVGMDVVLADGSLVTVGGYPRAALG
ECCCCCCCCHHHCCCEEEECCCCCCHHHCCCHHHEEEEEEEEEECCCEEEECCCCCHHCC
PDLMQVFIGSEGTLGVIVRVRLKLHRLPDYGRAIAYGFKTFAIGLDACREIMQRGANPAA
HHHHHHHHCCCCCEEEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
LRLYDELESGVQFGLPETNVLLVADEGTKEMVDAVMAISERVCAELGDRLDGDAIFERWL
EHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
DTRYLTGKSAEGFKRSPGFVADTLEMAGPWSDLAAIYTDVVAAINAVPGTLAGSAHQSHA
HHHEECCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCE
YVDGACLYFSLRGDVAVGDRQKWYRAAWDAANAVLIQYNAALSHHHGIGLLRAPYMAPSL
EECCEEEEEEECCCEEECCHHHHHHHHHCCCCEEEEEEECHHHHCCCCCEEECCCCCCCC
DTAFPVLVAVKRALDPQNILNPGKLGLSDVLPHEVKK
CHHHHHHHHHHHHCCHHHCCCCCCCCHHHCCCHHHCC
>Mature Secondary Structure
MISKEAIKRGYNRGNYVVGKHTPPHFAGSITATPDAPGLQRDAVAIDNDTLDALRKAADH
CCCHHHHHCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCCEEECCHHHHHHHHHHHH
VLTATSDVVEWTRDWWAGSMMTETGGKPATPRGVIVRVSTIEQIQAVMRIAHAKAIPVTV
HHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCEEEE
SAGRSNVTGAALPVRGGIVLDVCDVNRLLGFDRESQIVEVESGMFGDIFEQTIQQEYGMT
ECCCCCCCCCEEEECCCEEEEEECCHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCE
MGHWPSSYAISTVGGWVACRGAGQLSTRYGKIEDMVVGMDVVLADGSLVTVGGYPRAALG
ECCCCCCCCHHHCCCEEEECCCCCCHHHCCCHHHEEEEEEEEEECCCEEEECCCCCHHCC
PDLMQVFIGSEGTLGVIVRVRLKLHRLPDYGRAIAYGFKTFAIGLDACREIMQRGANPAA
HHHHHHHHCCCCCEEEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
LRLYDELESGVQFGLPETNVLLVADEGTKEMVDAVMAISERVCAELGDRLDGDAIFERWL
EHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
DTRYLTGKSAEGFKRSPGFVADTLEMAGPWSDLAAIYTDVVAAINAVPGTLAGSAHQSHA
HHHEECCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCE
YVDGACLYFSLRGDVAVGDRQKWYRAAWDAANAVLIQYNAALSHHHGIGLLRAPYMAPSL
EECCEEEEEEECCCEEECCHHHHHHHHHCCCCEEEEEEECHHHHCCCCCEEECCCCCCCC
DTAFPVLVAVKRALDPQNILNPGKLGLSDVLPHEVKK
CHHHHHHHHHHHHCCHHHCCCCCCCCHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 1-acyl-glycerone 3-phosphate; long-chain alcohol

Specific reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = an alkyl-glycerone 3-phosphate + a long-chain acid anion

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]