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The map label for this gene is abgR [H]

Identifier: 94314078

GI number: 94314078

Start: 1858484

End: 1859440

Strand: Direct

Name: abgR [H]

Synonym: Rmet_5159

Alternate gene names: 94314078

Gene position: 1858484-1859440 (Clockwise)

Preceding gene: 94314077

Following gene: 94314079

Centisome position: 72.03

GC content: 66.14

Gene sequence:

>957_bases
ATGCGCCTGAGCCAACTTCAGGACTTCATTGCCGTGGCCGAGACCGGCAGCATTCGGGCCGGCGCCAAGGCCCGCAATGT
CTCGGGTCCGGCCATCACCAAGAGCATTCGCCTGCTCGAGGAAGAACTGCACGTGCCGTTGCTGACACGCACTACGCGCG
GCGTGGTGCTGTCGCGCTATGGCGAGGCATTTTTGCGGCGCGCGCAGCTCATCGCCAGCGAGGCGCGCAAGGCCACCGAC
GAGATGTCGCAGATGCTGGGCACGCGCAATGGCGTGGTCCGTATCGGCGCCACGGGCGGCCCGGCGCACCTGCTGCTGCC
GGCCGTGCTCAAGCGCTTTCGATCGCAACACCCGGACGTCCAGGTCTGCATCGACAGCGGTGTCTATCCCGCCCACCTTT
CCGATCTGCGCGCCGGTGTCATGGACATGGCAGTCAGCCCAATTCCGGACGAGGGCATCGAGCGCGAGTTTGTCTCCGAG
CCGCTGTACGACAATGACTCGGTAGTGGTGGCGCACAAGGACCATCCACTGCGCAACGCCCGCAGGCTGCGCGAACTGGT
GGGATCGGAGTGGGTGCTGACGGGCCAGCGGATGCACGGCCCCGGCGCCGCGATTCTGGACGCCTTCCGTGCACTCGATC
TGCCGTTGCCACGCGTGGCCGTGCGTTGCGACACCATCGGCATGATCCAGACACTGCTTGAAGACCGGTCGCTGCTCTGC
CTGCTGCCGCGCCAGTTGGTGCCCGGCCAACTGGCCAGCGCCAATCTGGTGGCGCTGCCCATCGAGGATCCGTTGCCCAG
CCATGCGGTAAGCCTGATCTATCGGGCCGATTCTCCGATGACGCCCGTGGCGGAGCAGTTCGCCACGCTGTTGCGACGAG
AAGTGCACTATCTCGGTAAGCAGCCGGACAGCCCACTCCGCAGACAGGTACCCCGCGCCACGGAAATGGCCGGCTAG

Upstream 100 bases:

>100_bases
TGGTTGGCGGGTTGGGGGTGGTGGGAGCCCCAGCACATGGAAATGCGGCTATGCTGGCGGCAAAACGTCATCAAGAACGC
CAGCCACTGGGGACAATTTC

Downstream 100 bases:

>100_bases
CCTACTGCGGTCGAGCCGGGAACTTACTTTCAGTTGCGGGTGCTAACCAGCGGTTCACACCCGAACTGCCCCGAAAGGCC
GCCAGGCCGCGCCAGTACTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MRLSQLQDFIAVAETGSIRAGAKARNVSGPAITKSIRLLEEELHVPLLTRTTRGVVLSRYGEAFLRRAQLIASEARKATD
EMSQMLGTRNGVVRIGATGGPAHLLLPAVLKRFRSQHPDVQVCIDSGVYPAHLSDLRAGVMDMAVSPIPDEGIEREFVSE
PLYDNDSVVVAHKDHPLRNARRLRELVGSEWVLTGQRMHGPGAAILDAFRALDLPLPRVAVRCDTIGMIQTLLEDRSLLC
LLPRQLVPGQLASANLVALPIEDPLPSHAVSLIYRADSPMTPVAEQFATLLRREVHYLGKQPDSPLRRQVPRATEMAG

Sequences:

>Translated_318_residues
MRLSQLQDFIAVAETGSIRAGAKARNVSGPAITKSIRLLEEELHVPLLTRTTRGVVLSRYGEAFLRRAQLIASEARKATD
EMSQMLGTRNGVVRIGATGGPAHLLLPAVLKRFRSQHPDVQVCIDSGVYPAHLSDLRAGVMDMAVSPIPDEGIEREFVSE
PLYDNDSVVVAHKDHPLRNARRLRELVGSEWVLTGQRMHGPGAAILDAFRALDLPLPRVAVRCDTIGMIQTLLEDRSLLC
LLPRQLVPGQLASANLVALPIEDPLPSHAVSLIYRADSPMTPVAEQFATLLRREVHYLGKQPDSPLRRQVPRATEMAG
>Mature_318_residues
MRLSQLQDFIAVAETGSIRAGAKARNVSGPAITKSIRLLEEELHVPLLTRTTRGVVLSRYGEAFLRRAQLIASEARKATD
EMSQMLGTRNGVVRIGATGGPAHLLLPAVLKRFRSQHPDVQVCIDSGVYPAHLSDLRAGVMDMAVSPIPDEGIEREFVSE
PLYDNDSVVVAHKDHPLRNARRLRELVGSEWVLTGQRMHGPGAAILDAFRALDLPLPRVAVRCDTIGMIQTLLEDRSLLC
LLPRQLVPGQLASANLVALPIEDPLPSHAVSLIYRADSPMTPVAEQFATLLRREVHYLGKQPDSPLRRQVPRATEMAG

Specific function: Could be the regulator of the abg operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=298, Percent_Identity=32.8859060402685, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1789506, Length=294, Percent_Identity=23.8095238095238, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI145693105, Length=305, Percent_Identity=26.2295081967213, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790399, Length=299, Percent_Identity=26.7558528428094, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87081904, Length=306, Percent_Identity=24.5098039215686, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788887, Length=298, Percent_Identity=27.5167785234899, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788481, Length=270, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786401, Length=178, Percent_Identity=29.2134831460674, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787128, Length=122, Percent_Identity=33.6065573770492, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790208, Length=150, Percent_Identity=28.6666666666667, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI157672245, Length=288, Percent_Identity=25.3472222222222, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787879, Length=183, Percent_Identity=29.5081967213115, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789639, Length=144, Percent_Identity=27.7777777777778, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34860; Mature: 34860

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSQLQDFIAVAETGSIRAGAKARNVSGPAITKSIRLLEEELHVPLLTRTTRGVVLSRY
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GEAFLRRAQLIASEARKATDEMSQMLGTRNGVVRIGATGGPAHLLLPAVLKRFRSQHPDV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCE
QVCIDSGVYPAHLSDLRAGVMDMAVSPIPDEGIEREFVSEPLYDNDSVVVAHKDHPLRNA
EEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCEEEEECCCCHHHH
RRLRELVGSEWVLTGQRMHGPGAAILDAFRALDLPLPRVAVRCDTIGMIQTLLEDRSLLC
HHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEE
LLPRQLVPGQLASANLVALPIEDPLPSHAVSLIYRADSPMTPVAEQFATLLRREVHYLGK
ECCHHHCCCCCCCCCEEEEECCCCCCHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCC
QPDSPLRRQVPRATEMAG
CCCCHHHHHCCCHHHCCC
>Mature Secondary Structure
MRLSQLQDFIAVAETGSIRAGAKARNVSGPAITKSIRLLEEELHVPLLTRTTRGVVLSRY
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GEAFLRRAQLIASEARKATDEMSQMLGTRNGVVRIGATGGPAHLLLPAVLKRFRSQHPDV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCE
QVCIDSGVYPAHLSDLRAGVMDMAVSPIPDEGIEREFVSEPLYDNDSVVVAHKDHPLRNA
EEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCEEEEECCCCHHHH
RRLRELVGSEWVLTGQRMHGPGAAILDAFRALDLPLPRVAVRCDTIGMIQTLLEDRSLLC
HHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEE
LLPRQLVPGQLASANLVALPIEDPLPSHAVSLIYRADSPMTPVAEQFATLLRREVHYLGK
ECCHHHCCCCCCCCCEEEEECCCCCCHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCC
QPDSPLRRQVPRATEMAG
CCCCHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9829935 [H]