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The map label for this gene is oxlT [H]

Identifier: 94313291

GI number: 94313291

Start: 963645

End: 964988

Strand: Direct

Name: oxlT [H]

Synonym: Rmet_4366

Alternate gene names: 94313291

Gene position: 963645-964988 (Clockwise)

Preceding gene: 94313288

Following gene: 94313292

Centisome position: 37.35

GC content: 64.51

Gene sequence:

>1344_bases
ATGGCGCACACCAACGCGGCAGGCCCCGCCGTGGGCAACTTCAACGGCGGGCTGCTTCGCAACCGCTGGTTCCAGCTCTT
CATCGGCGTGATCTGCATGGGGCTGGTGGCCAACCTCCAGTATGGCTGGACATTGTTCGTCACCCCCATGAATGCCCGGC
ACCACTGGGGCGAATCGGCGATCCAGGTCGCATTTTCCATTTTCATCGTCACCGAAACCTGGCTCGTGCCGCTGGAAGGC
TGGCTCGTCGACAAGTTCGGGCCCCGCCCCGTGGTGGCCGGCGGCGCGATCTGTGCCGGACTGGCGTGGGTGATGAACTC
GTACGCCACGACCCTGCCGATGCTGTACACGGCTGCCGTGATCGCGGGGATTGGCGCCGGCGGTGTCTATGGCACGTGCG
TCGGCAATGCGCTGAAGTGGTTCCCGGACAAGCGCGGCCTGGCGGCAGGACTGACCGCTGCGGGCTTCGGCGCGGGCTCG
GCGCTGACGGTGATTCCCATCGCCAACATGATCCAGAAGTCCGGCTATGAGCACGCCTTCTTCACATTCGGCATCCTGCA
GGGTGTGCTGATCTTCGCGATGGCGCTGCTGCTGGTGAAGCCGCAGCCGCCCAAGGGCGTGGTGGCGAACAAGGCCATCC
TGACCAACCCGGTTGAGTTCACGCCGGGCCAGATGGTGCGCACGCCGGTCTTCTGGGTGATCTATGCCTCGTTCGTGGCG
GTGGCCGCGGGCGGCATCATGGCTACCGCGCAGCTTGGGCCGATTGCCAAGGACTTCGGGTTTGCCTCGATGCCGGTCAC
GATGCTTGGCATGACACTGCCGCTGCTGACGATGACGCTGTCGATTGACAATCTTTGCAACGGGCTCACGCGTCCGCTGT
GCGGCTTTATTTCCGACCGCATCGGCCGCGAGAACACGATGTTCGTGATCTTCATTGGTGAAGGACTGTCGCTGATCGGG
CTCCTCGAACTGGGCCATGACCCCTACTGGTTCATGCTCTTCGCCGCGCTGACCTTCCTGTTCTGGGGCGAGATCTTTTC
GATCTTCCCCGCGCTCTGCGCCGATACGTTTGGCAGCAAGTTTGCCGCGGCCAACGCCGGCACGCTCTACACGGCGAAGG
GCACCGCCGCGCTGCTGGTGCCGCTGGCGTCCGTGCTGTCCCACCACGGTGGCTGGAACCTGGTGTTCACGGTGGCGGCC
GTAATGACCGTGGCGGCCGGGCTTTCCGCCAAGTTCGTGCTGCAGCCGATGCGTCGCCGCTTCATCACCGGCCACGCGAT
GGCGCAGCCGGTCAGCGATCACGCGACATACATGGCCGGGTTCTCGACCGGCAAGGGTGAATAA

Upstream 100 bases:

>100_bases
AGGCGCGCTCATTCAGTAGTGAAAAAGTCGGGCGTCCACAAGGCCAGCCCAGCAGTCGCGCCACCAGAGCGCGAAAGACA
CTAATGCAAGGAGACACGAC

Downstream 100 bases:

>100_bases
CCGGTCCGGCGAATGCGGAAAGGAGCGGCAGCATGAATGTATCGCTTCCCCAGTTGAAGGCTTTCGCTGCGGTGGCTCGC
CAAAAGAGCTTCACGCGAGC

Product: major facilitator superfamily transporter

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MAHTNAAGPAVGNFNGGLLRNRWFQLFIGVICMGLVANLQYGWTLFVTPMNARHHWGESAIQVAFSIFIVTETWLVPLEG
WLVDKFGPRPVVAGGAICAGLAWVMNSYATTLPMLYTAAVIAGIGAGGVYGTCVGNALKWFPDKRGLAAGLTAAGFGAGS
ALTVIPIANMIQKSGYEHAFFTFGILQGVLIFAMALLLVKPQPPKGVVANKAILTNPVEFTPGQMVRTPVFWVIYASFVA
VAAGGIMATAQLGPIAKDFGFASMPVTMLGMTLPLLTMTLSIDNLCNGLTRPLCGFISDRIGRENTMFVIFIGEGLSLIG
LLELGHDPYWFMLFAALTFLFWGEIFSIFPALCADTFGSKFAAANAGTLYTAKGTAALLVPLASVLSHHGGWNLVFTVAA
VMTVAAGLSAKFVLQPMRRRFITGHAMAQPVSDHATYMAGFSTGKGE

Sequences:

>Translated_447_residues
MAHTNAAGPAVGNFNGGLLRNRWFQLFIGVICMGLVANLQYGWTLFVTPMNARHHWGESAIQVAFSIFIVTETWLVPLEG
WLVDKFGPRPVVAGGAICAGLAWVMNSYATTLPMLYTAAVIAGIGAGGVYGTCVGNALKWFPDKRGLAAGLTAAGFGAGS
ALTVIPIANMIQKSGYEHAFFTFGILQGVLIFAMALLLVKPQPPKGVVANKAILTNPVEFTPGQMVRTPVFWVIYASFVA
VAAGGIMATAQLGPIAKDFGFASMPVTMLGMTLPLLTMTLSIDNLCNGLTRPLCGFISDRIGRENTMFVIFIGEGLSLIG
LLELGHDPYWFMLFAALTFLFWGEIFSIFPALCADTFGSKFAAANAGTLYTAKGTAALLVPLASVLSHHGGWNLVFTVAA
VMTVAAGLSAKFVLQPMRRRFITGHAMAQPVSDHATYMAGFSTGKGE
>Mature_446_residues
AHTNAAGPAVGNFNGGLLRNRWFQLFIGVICMGLVANLQYGWTLFVTPMNARHHWGESAIQVAFSIFIVTETWLVPLEGW
LVDKFGPRPVVAGGAICAGLAWVMNSYATTLPMLYTAAVIAGIGAGGVYGTCVGNALKWFPDKRGLAAGLTAAGFGAGSA
LTVIPIANMIQKSGYEHAFFTFGILQGVLIFAMALLLVKPQPPKGVVANKAILTNPVEFTPGQMVRTPVFWVIYASFVAV
AAGGIMATAQLGPIAKDFGFASMPVTMLGMTLPLLTMTLSIDNLCNGLTRPLCGFISDRIGRENTMFVIFIGEGLSLIGL
LELGHDPYWFMLFAALTFLFWGEIFSIFPALCADTFGSKFAAANAGTLYTAKGTAALLVPLASVLSHHGGWNLVFTVAAV
MTVAAGLSAKFVLQPMRRRFITGHAMAQPVSDHATYMAGFSTGKGE

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Escherichia coli, GI1789969, Length=411, Percent_Identity=24.5742092457421, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI193209150, Length=335, Percent_Identity=24.7761194029851, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47422; Mature: 47291

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHTNAAGPAVGNFNGGLLRNRWFQLFIGVICMGLVANLQYGWTLFVTPMNARHHWGESA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHCCHHH
IQVAFSIFIVTETWLVPLEGWLVDKFGPRPVVAGGAICAGLAWVMNSYATTLPMLYTAAV
HHHHHHHHEEEHHHEEECCCEEECCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
IAGIGAGGVYGTCVGNALKWFPDKRGLAAGLTAAGFGAGSALTVIPIANMIQKSGYEHAF
HHHCCCCCHHHHHHHHHHHHCCCCCCCHHCCHHHCCCCCCCCHHHHHHHHHHHCCCCHHH
FTFGILQGVLIFAMALLLVKPQPPKGVVANKAILTNPVEFTPGQMVRTPVFWVIYASFVA
HHHHHHHHHHHHHHHHHHCCCCCCCCCEECCHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
VAAGGIMATAQLGPIAKDFGFASMPVTMLGMTLPLLTMTLSIDNLCNGLTRPLCGFISDR
HHHCCHHEEHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGRENTMFVIFIGEGLSLIGLLELGHDPYWFMLFAALTFLFWGEIFSIFPALCADTFGSK
CCCCCCEEEEEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FAAANAGTLYTAKGTAALLVPLASVLSHHGGWNLVFTVAAVMTVAAGLSAKFVLQPMRRR
CCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FITGHAMAQPVSDHATYMAGFSTGKGE
HHHHHHHHCCHHHHHHEEEECCCCCCC
>Mature Secondary Structure 
AHTNAAGPAVGNFNGGLLRNRWFQLFIGVICMGLVANLQYGWTLFVTPMNARHHWGESA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHCCHHH
IQVAFSIFIVTETWLVPLEGWLVDKFGPRPVVAGGAICAGLAWVMNSYATTLPMLYTAAV
HHHHHHHHEEEHHHEEECCCEEECCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
IAGIGAGGVYGTCVGNALKWFPDKRGLAAGLTAAGFGAGSALTVIPIANMIQKSGYEHAF
HHHCCCCCHHHHHHHHHHHHCCCCCCCHHCCHHHCCCCCCCCHHHHHHHHHHHCCCCHHH
FTFGILQGVLIFAMALLLVKPQPPKGVVANKAILTNPVEFTPGQMVRTPVFWVIYASFVA
HHHHHHHHHHHHHHHHHHCCCCCCCCCEECCHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
VAAGGIMATAQLGPIAKDFGFASMPVTMLGMTLPLLTMTLSIDNLCNGLTRPLCGFISDR
HHHCCHHEEHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGRENTMFVIFIGEGLSLIGLLELGHDPYWFMLFAALTFLFWGEIFSIFPALCADTFGSK
CCCCCCEEEEEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FAAANAGTLYTAKGTAALLVPLASVLSHHGGWNLVFTVAAVMTVAAGLSAKFVLQPMRRR
CCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FITGHAMAQPVSDHATYMAGFSTGKGE
HHHHHHHHCCHHHHHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]