Click here to switch to the map view.

The map label for this gene is yfeR [H]

Identifier: 94313292

GI number: 94313292

Start: 965021

End: 965950

Strand: Direct

Name: yfeR [H]

Synonym: Rmet_4367

Alternate gene names: 94313292

Gene position: 965021-965950 (Clockwise)

Preceding gene: 94313291

Following gene: 94313293

Centisome position: 37.4

GC content: 65.16

Gene sequence:

>930_bases
ATGAATGTATCGCTTCCCCAGTTGAAGGCTTTCGCTGCGGTGGCTCGCCAAAAGAGCTTCACGCGAGCCGCGGCAGAGCT
TGGGCTGACACAGTCGGCCATCAGCCGGAGCGTGCGCGAACTGGAAGAGGAGATCGACCAGCGGCTGTTCGATCGCACCA
CGCGCCAGGTGGAGTTGACCGATGCGGGCGAGATGCTGTCGCAACGGATCTGCCATCTGGTCGAGGAAGTCGAACAGACA
CTGCGCGATAGCCACGGCACCGGCAAACCGTGTGAAGGCACGGTGCAGATCGCCACCGATCCGGTGTTGTCATCGATGAC
GCTGCCGATGTGGGTGGCTGGCTGCCGCAAGGCGTGGCCCGGCATCGGCATCACGCTGCGCGACTGCTCGCATGAATGCG
TGCTGCAGCGTGTGCGTAGCGGAGAGGTCGATTTCGGCATCGCCAGCAATCCGGCGCCTTGCGACGATCTTTACTGTGAA
CCCCTGTGCGTGGATCCTTTCCAGGCCGTGCTGCCGGCGGGGCATCCTCTGGCGGCGCGGGAGTCACTGGGGTGGGGCGA
ACTGGGCGATGCGTCGGTGCTGACGCTCGATCAGAGTTCCGGCATCCAGCCCGCGGTGGAGCGCGCGCTGGCCGCCTATC
GCGTACGCCCGGGCTCGTTGCAGGTACTGGGCCATTTTGCTGCGGTATTCGGCATGGTGGCGATGGGGTTGGGGATCGGT
GTGGTGCCATCGCGGGCGCAGGCCGCTGGTATTGCGCCCTCGGCAGTGCTGCGCCCGTTGCGTCCGCAGGTGACCTCGAA
CGTCATGCTCGTGCGCCGCAAGGCCCGGTCGCTCAAGCCAAATGCGGCGGCGGTGTGGGACAACCTGCGTGCCCAGGAGT
ACGAGCGTGGCGATTACGGCAATCAGGGGTTGCTGAAGAAAGTGGGGTAG

Upstream 100 bases:

>100_bases
CGATGGCGCAGCCGGTCAGCGATCACGCGACATACATGGCCGGGTTCTCGACCGGCAAGGGTGAATAACCGGTCCGGCGA
ATGCGGAAAGGAGCGGCAGC

Downstream 100 bases:

>100_bases
GGCATTGAATCGAATTCACGTGCGGCACTGCCGCAGGCGTATTCCGATCAACTTTTGATGCGACGGACGTTCAATTTGAG
ATGCGCAACGCACCCTACGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MNVSLPQLKAFAAVARQKSFTRAAAELGLTQSAISRSVRELEEEIDQRLFDRTTRQVELTDAGEMLSQRICHLVEEVEQT
LRDSHGTGKPCEGTVQIATDPVLSSMTLPMWVAGCRKAWPGIGITLRDCSHECVLQRVRSGEVDFGIASNPAPCDDLYCE
PLCVDPFQAVLPAGHPLAARESLGWGELGDASVLTLDQSSGIQPAVERALAAYRVRPGSLQVLGHFAAVFGMVAMGLGIG
VVPSRAQAAGIAPSAVLRPLRPQVTSNVMLVRRKARSLKPNAAAVWDNLRAQEYERGDYGNQGLLKKVG

Sequences:

>Translated_309_residues
MNVSLPQLKAFAAVARQKSFTRAAAELGLTQSAISRSVRELEEEIDQRLFDRTTRQVELTDAGEMLSQRICHLVEEVEQT
LRDSHGTGKPCEGTVQIATDPVLSSMTLPMWVAGCRKAWPGIGITLRDCSHECVLQRVRSGEVDFGIASNPAPCDDLYCE
PLCVDPFQAVLPAGHPLAARESLGWGELGDASVLTLDQSSGIQPAVERALAAYRVRPGSLQVLGHFAAVFGMVAMGLGIG
VVPSRAQAAGIAPSAVLRPLRPQVTSNVMLVRRKARSLKPNAAAVWDNLRAQEYERGDYGNQGLLKKVG
>Mature_309_residues
MNVSLPQLKAFAAVARQKSFTRAAAELGLTQSAISRSVRELEEEIDQRLFDRTTRQVELTDAGEMLSQRICHLVEEVEQT
LRDSHGTGKPCEGTVQIATDPVLSSMTLPMWVAGCRKAWPGIGITLRDCSHECVLQRVRSGEVDFGIASNPAPCDDLYCE
PLCVDPFQAVLPAGHPLAARESLGWGELGDASVLTLDQSSGIQPAVERALAAYRVRPGSLQVLGHFAAVFGMVAMGLGIG
VVPSRAQAAGIAPSAVLRPLRPQVTSNVMLVRRKARSLKPNAAAVWDNLRAQEYERGDYGNQGLLKKVG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788748, Length=292, Percent_Identity=40.0684931506849, Blast_Score=207, Evalue=8e-55,
Organism=Escherichia coli, GI145693105, Length=283, Percent_Identity=29.3286219081272, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI157672245, Length=190, Percent_Identity=32.6315789473684, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788887, Length=281, Percent_Identity=27.7580071174377, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787879, Length=252, Percent_Identity=26.984126984127, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788481, Length=267, Percent_Identity=27.7153558052434, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787601, Length=178, Percent_Identity=29.2134831460674, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787128, Length=126, Percent_Identity=35.7142857142857, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788297, Length=242, Percent_Identity=26.0330578512397, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790399, Length=302, Percent_Identity=25.1655629139073, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87081904, Length=177, Percent_Identity=27.1186440677966, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1786401, Length=163, Percent_Identity=29.4478527607362, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789639, Length=125, Percent_Identity=33.6, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI2367136, Length=269, Percent_Identity=23.4200743494424, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790262, Length=247, Percent_Identity=25.1012145748988, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787589, Length=122, Percent_Identity=35.2459016393443, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788706, Length=180, Percent_Identity=28.3333333333333, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788296, Length=247, Percent_Identity=26.7206477732794, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786448, Length=74, Percent_Identity=45.945945945946, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1787806, Length=244, Percent_Identity=22.5409836065574, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789506, Length=166, Percent_Identity=25.9036144578313, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789204, Length=284, Percent_Identity=23.5915492957746, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33308; Mature: 33308

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS50287 SRCR_2 ; PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVSLPQLKAFAAVARQKSFTRAAAELGLTQSAISRSVRELEEEIDQRLFDRTTRQVELT
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEC
DAGEMLSQRICHLVEEVEQTLRDSHGTGKPCEGTVQIATDPVLSSMTLPMWVAGCRKAWP
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCC
GIGITLRDCSHECVLQRVRSGEVDFGIASNPAPCDDLYCEPLCVDPFQAVLPAGHPLAAR
CCCEEHHCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHCCCCCCCHHH
ESLGWGELGDASVLTLDQSSGIQPAVERALAAYRVRPGSLQVLGHFAAVFGMVAMGLGIG
HCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
VVPSRAQAAGIAPSAVLRPLRPQVTSNVMLVRRKARSLKPNAAAVWDNLRAQEYERGDYG
CCCCCHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
NQGLLKKVG
CCCHHHHCC
>Mature Secondary Structure
MNVSLPQLKAFAAVARQKSFTRAAAELGLTQSAISRSVRELEEEIDQRLFDRTTRQVELT
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEC
DAGEMLSQRICHLVEEVEQTLRDSHGTGKPCEGTVQIATDPVLSSMTLPMWVAGCRKAWP
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCC
GIGITLRDCSHECVLQRVRSGEVDFGIASNPAPCDDLYCEPLCVDPFQAVLPAGHPLAAR
CCCEEHHCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHCCCCCCCHHH
ESLGWGELGDASVLTLDQSSGIQPAVERALAAYRVRPGSLQVLGHFAAVFGMVAMGLGIG
HCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
VVPSRAQAAGIAPSAVLRPLRPQVTSNVMLVRRKARSLKPNAAAVWDNLRAQEYERGDYG
CCCCCHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
NQGLLKKVG
CCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]