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The map label for this gene is ycgM [C]

Identifier: 94313288

GI number: 94313288

Start: 961214

End: 961990

Strand: Direct

Name: ycgM [C]

Synonym: Rmet_4363

Alternate gene names: 94313288

Gene position: 961214-961990 (Clockwise)

Preceding gene: 94313287

Following gene: 94313291

Centisome position: 37.26

GC content: 65.38

Gene sequence:

>777_bases
ATGCAGCAAACCTGGATTCGCTTCCGCAGCCCACGCGGAGACACTGGCTTCGGCCTCGTCGATGGCGATCGCGTCATCGT
GTACGACGGCCCCGGCTACACCGGCTCGAAGCCCACCGGCGCCGTGCTGCCCCGCGACGAAGTGCACCTGCTGGCGCCGT
GCGAGCCGGGCAAGATCGTCGCGCTATGGAACAACTTCCACGCGCTGGCGCGCAAGCTCGAGAAGCCCGTGCCGCTGCAT
CCGTTGTTCCTGATGAAGCCGGCCAGTTCGCTGGCCGGGCCTGGCGATGCCATCGAGCGGCCCGCCAGCTATCGCGGCAA
GATCGTCTATGAAGGCGAGCTCGGGATCGTTATCGGCCGCAAATGCCGCAATGTGGGCGTGTCGGAGGCGGCCTCGCACA
TCTTTGGCTACACGGTGGTCAACGATGTCACCGCGGCCGAGTTGATCACCGAAGACCCGAACTTCCCGCAGTGGACGCGG
GCCAAGGGTTACGACACGTTCGGCTGTCTGGGGCCGGGCATCGTCACCGGCTTCGACTGGCGCGCCGCCAGCGTTGTAAC
GCGGCTCGATGGCGTGGAGCGGCAGAACTATCCGCTCGCCGACATGGTCTTCTCGCCCGAAGAACAGGTCAGCCGGATCT
CACAGGATCTGACGCTGATGCCCGGCGACGTGATTGCCTGCGGTACTTCGCTCGGTGTCGGATCGATGAAGGACGGCGCG
GTGGTCGAGGTGTCGATCGCCGGAATCGGCGCCTTGGTCAACCACGTGAAGGGATAG

Upstream 100 bases:

>100_bases
CGCTGGCGTGAGAGGGAAAGAGGGCCAGCGCTTCCATTGCCAAGGCCCTCGACATGACAGCCCACGTCGAGGGCTTCTTC
TTTTTTCATAAGGAGCCCCC

Downstream 100 bases:

>100_bases
CTGAAGGGCGGCAAAAGGCCCCCCACAACTGCAAGGGGCCTTTTCACCGAGAGAAAGGCTCGGCGATCAGTTGACGCCGG
CGCCTGCCATTGCCCGCATG

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MQQTWIRFRSPRGDTGFGLVDGDRVIVYDGPGYTGSKPTGAVLPRDEVHLLAPCEPGKIVALWNNFHALARKLEKPVPLH
PLFLMKPASSLAGPGDAIERPASYRGKIVYEGELGIVIGRKCRNVGVSEAASHIFGYTVVNDVTAAELITEDPNFPQWTR
AKGYDTFGCLGPGIVTGFDWRAASVVTRLDGVERQNYPLADMVFSPEEQVSRISQDLTLMPGDVIACGTSLGVGSMKDGA
VVEVSIAGIGALVNHVKG

Sequences:

>Translated_258_residues
MQQTWIRFRSPRGDTGFGLVDGDRVIVYDGPGYTGSKPTGAVLPRDEVHLLAPCEPGKIVALWNNFHALARKLEKPVPLH
PLFLMKPASSLAGPGDAIERPASYRGKIVYEGELGIVIGRKCRNVGVSEAASHIFGYTVVNDVTAAELITEDPNFPQWTR
AKGYDTFGCLGPGIVTGFDWRAASVVTRLDGVERQNYPLADMVFSPEEQVSRISQDLTLMPGDVIACGTSLGVGSMKDGA
VVEVSIAGIGALVNHVKG
>Mature_258_residues
MQQTWIRFRSPRGDTGFGLVDGDRVIVYDGPGYTGSKPTGAVLPRDEVHLLAPCEPGKIVALWNNFHALARKLEKPVPLH
PLFLMKPASSLAGPGDAIERPASYRGKIVYEGELGIVIGRKCRNVGVSEAASHIFGYTVVNDVTAAELITEDPNFPQWTR
AKGYDTFGCLGPGIVTGFDWRAASVVTRLDGVERQNYPLADMVFSPEEQVSRISQDLTLMPGDVIACGTSLGVGSMKDGA
VVEVSIAGIGALVNHVKG

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI40786394, Length=226, Percent_Identity=35.3982300884956, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI156231349, Length=226, Percent_Identity=35.3982300884956, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI13654274, Length=204, Percent_Identity=30.3921568627451, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI66348062, Length=196, Percent_Identity=31.1224489795918, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI215422413, Length=196, Percent_Identity=31.1224489795918, Blast_Score=83, Evalue=2e-16,
Organism=Escherichia coli, GI1787428, Length=196, Percent_Identity=25.5102040816327, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17557057, Length=198, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28572127, Length=248, Percent_Identity=33.8709677419355, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24663695, Length=221, Percent_Identity=34.3891402714932, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28571789, Length=206, Percent_Identity=32.5242718446602, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 27648; Mature: 27648

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQTWIRFRSPRGDTGFGLVDGDRVIVYDGPGYTGSKPTGAVLPRDEVHLLAPCEPGKIV
CCCCEEEEECCCCCCCCEEECCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCEE
ALWNNFHALARKLEKPVPLHPLFLMKPASSLAGPGDAIERPASYRGKIVYEGELGIVIGR
EEECCHHHHHHHHCCCCCCCCEEEECCHHHCCCCCHHHCCCCCCCCEEEEECCEEEEECC
KCRNVGVSEAASHIFGYTVVNDVTAAELITEDPNFPQWTRAKGYDTFGCLGPGIVTGFDW
CHHCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCC
RAASVVTRLDGVERQNYPLADMVFSPEEQVSRISQDLTLMPGDVIACGTSLGVGSMKDGA
HHHHHHHHHCCCCCCCCCHHHEEECCHHHHHHHHHCCEECCCCEEEECCCCCCCCCCCCC
VVEVSIAGIGALVNHVKG
EEEEEEHHHHHHHHHHCC
>Mature Secondary Structure
MQQTWIRFRSPRGDTGFGLVDGDRVIVYDGPGYTGSKPTGAVLPRDEVHLLAPCEPGKIV
CCCCEEEEECCCCCCCCEEECCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCEE
ALWNNFHALARKLEKPVPLHPLFLMKPASSLAGPGDAIERPASYRGKIVYEGELGIVIGR
EEECCHHHHHHHHCCCCCCCCEEEECCHHHCCCCCHHHCCCCCCCCEEEEECCEEEEECC
KCRNVGVSEAASHIFGYTVVNDVTAAELITEDPNFPQWTRAKGYDTFGCLGPGIVTGFDW
CHHCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCC
RAASVVTRLDGVERQNYPLADMVFSPEEQVSRISQDLTLMPGDVIACGTSLGVGSMKDGA
HHHHHHHHHCCCCCCCCCHHHEEECCHHHHHHHHHCCEECCCCEEEECCCCCCCCCCCCC
VVEVSIAGIGALVNHVKG
EEEEEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]