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The map label for this gene is ecpD [H]

Identifier: 94313177

GI number: 94313177

Start: 837241

End: 837993

Strand: Direct

Name: ecpD [H]

Synonym: Rmet_4251

Alternate gene names: 94313177

Gene position: 837241-837993 (Clockwise)

Preceding gene: 94313176

Following gene: 94313178

Centisome position: 32.45

GC content: 62.68

Gene sequence:

>753_bases
ATGATCATGACACGCACGCGGATGATTCGATATGTCTGGACCACGACTTTGCTGCTGGTACTCGGTCTGGCCGTTGTGTT
GCAGGCCGAGGCATCGGTGGTCCTTGCCGGCACGCGCGTGATTTTTAACGCCAATGAGCGTGAGACGACGGTCAGGCTGA
GCAACGAGGGCAAGGTGCCAGCGCTCACGCAGGTGTGGCTGGACAAGGGCGATCCCAAAGCGGCACCCTCGGAGATCTCC
GTGCCGTTCACGGTAACACCGCCGGTATCGCGCATCGACCCTGGTAAGGGGCAGACGCTGCGGATCTTTTATACCGGTGA
GGCGCTGCCGCGGGACAAGGAATCGGTCTTCTGGCTGAACGTGCTGGAGATTCCGCCCGAAGCCAGTGGGGAGGCCAACA
AGCTGCAACTGGCCTTCCGCACGCGCATCAAGCTCTTCTTCCGGCCGGCCGGGCTGGCCGGCACGGCGCAGGATGCGCCA
GCCAAGACCGAGTGGCGGTTGCTGCCGGGCGGCAAGCAGGTGCAGGTTCGCAATCCAACGCCGTACTTCATCTCGTTCTC
TGCTTTCGAGATCGAGGGCAATGGCAAGTCGGTGAAATTCGATGATGGCGGCATGGTCGGCCCCGGAGACACACAGGTGT
TTGCGCTGAACACCGCTGCGACTCCCGCGCCCGGCCTGAAGGTTCACTACCACGCCATCAGCGACTTTGGTGGCGCCATT
GACGGAGAGGCCGCGCTCGCCGTCACTCCATGA

Upstream 100 bases:

>100_bases
GCGTGATGTACACCATCGCCTACAACTAAGCCGGAAACGGATGGCGGAATCTCACAGTTCTGCCATCCACCTGCTTTGGA
TTTGACCCTGTCTTCCTGAA

Downstream 100 bases:

>100_bases
TGCTCTCGTCGGCTGCCTAGGGCAGCCCCTTTCCAGACTCCTTCCTTTGTGGGCAAGACCCCGGTCTGCCGATCAGGGCA
GCAGTCTGTCCGCTGTTTCT

Product: periplasmic pilus chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MIMTRTRMIRYVWTTTLLLVLGLAVVLQAEASVVLAGTRVIFNANERETTVRLSNEGKVPALTQVWLDKGDPKAAPSEIS
VPFTVTPPVSRIDPGKGQTLRIFYTGEALPRDKESVFWLNVLEIPPEASGEANKLQLAFRTRIKLFFRPAGLAGTAQDAP
AKTEWRLLPGGKQVQVRNPTPYFISFSAFEIEGNGKSVKFDDGGMVGPGDTQVFALNTAATPAPGLKVHYHAISDFGGAI
DGEAALAVTP

Sequences:

>Translated_250_residues
MIMTRTRMIRYVWTTTLLLVLGLAVVLQAEASVVLAGTRVIFNANERETTVRLSNEGKVPALTQVWLDKGDPKAAPSEIS
VPFTVTPPVSRIDPGKGQTLRIFYTGEALPRDKESVFWLNVLEIPPEASGEANKLQLAFRTRIKLFFRPAGLAGTAQDAP
AKTEWRLLPGGKQVQVRNPTPYFISFSAFEIEGNGKSVKFDDGGMVGPGDTQVFALNTAATPAPGLKVHYHAISDFGGAI
DGEAALAVTP
>Mature_250_residues
MIMTRTRMIRYVWTTTLLLVLGLAVVLQAEASVVLAGTRVIFNANERETTVRLSNEGKVPALTQVWLDKGDPKAAPSEIS
VPFTVTPPVSRIDPGKGQTLRIFYTGEALPRDKESVFWLNVLEIPPEASGEANKLQLAFRTRIKLFFRPAGLAGTAQDAP
AKTEWRLLPGGKQVQVRNPTPYFISFSAFEIEGNGKSVKFDDGGMVGPGDTQVFALNTAATPAPGLKVHYHAISDFGGAI
DGEAALAVTP

Specific function: Probably mediates assembly of a pilin [H]

COG id: COG3121

COG function: function code NU; P pilus assembly protein, chaperone PapD

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1786333, Length=240, Percent_Identity=48.3333333333333, Blast_Score=221, Evalue=3e-59,
Organism=Escherichia coli, GI1788428, Length=239, Percent_Identity=34.3096234309623, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1789532, Length=237, Percent_Identity=32.9113924050633, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1787171, Length=206, Percent_Identity=35.4368932038835, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788677, Length=161, Percent_Identity=39.1304347826087, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1790771, Length=238, Percent_Identity=29.8319327731092, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1786936, Length=226, Percent_Identity=29.2035398230088, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1786743, Length=196, Percent_Identity=30.1020408163265, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI87081806, Length=225, Percent_Identity=31.1111111111111, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082203, Length=153, Percent_Identity=30.0653594771242, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 26991; Mature: 26991

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMTRTRMIRYVWTTTLLLVLGLAVVLQAEASVVLAGTRVIFNANERETTVRLSNEGKVP
CEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCEEEEEECCCCCCC
ALTQVWLDKGDPKAAPSEISVPFTVTPPVSRIDPGKGQTLRIFYTGEALPRDKESVFWLN
EEEEEEECCCCCCCCCCCEECCEEECCCHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEE
VLEIPPEASGEANKLQLAFRTRIKLFFRPAGLAGTAQDAPAKTEWRLLPGGKQVQVRNPT
EEECCCCCCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCEEEEECCC
PYFISFSAFEIEGNGKSVKFDDGGMVGPGDTQVFALNTAATPAPGLKVHYHAISDFGGAI
CEEEEEEEEEEECCCCEEEECCCCEECCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCC
DGEAALAVTP
CCCEEEEECC
>Mature Secondary Structure
MIMTRTRMIRYVWTTTLLLVLGLAVVLQAEASVVLAGTRVIFNANERETTVRLSNEGKVP
CEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCEEEEEECCCCCCC
ALTQVWLDKGDPKAAPSEISVPFTVTPPVSRIDPGKGQTLRIFYTGEALPRDKESVFWLN
EEEEEEECCCCCCCCCCCEECCEEECCCHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEE
VLEIPPEASGEANKLQLAFRTRIKLFFRPAGLAGTAQDAPAKTEWRLLPGGKQVQVRNPT
EEECCCCCCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCEEEEECCC
PYFISFSAFEIEGNGKSVKFDDGGMVGPGDTQVFALNTAATPAPGLKVHYHAISDFGGAI
CEEEEEEEEEEECCCCEEEECCCCEECCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCC
DGEAALAVTP
CCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8102362; 8202364; 9278503 [H]