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The map label for this gene is ccmB [H]

Identifier: 94312987

GI number: 94312987

Start: 625441

End: 626109

Strand: Reverse

Name: ccmB [H]

Synonym: Rmet_4059

Alternate gene names: 94312987

Gene position: 626109-625441 (Counterclockwise)

Preceding gene: 94312988

Following gene: 94312986

Centisome position: 24.27

GC content: 68.16

Gene sequence:

>669_bases
ATGATCCAGGCCATCGGCACGATCATCGCGCACGACCTGTCGATCGCATGGCGGCGGCGCACCGGGCTGCTTTCCAGCCT
GGTCTTCTTCGTCATCGCCACGAGCCTCTTTCCGCTGGCCATCGGCCCGGACCCGCAGCAATTGCGCGCGCTGGCGCCGG
GCATCCTGTGGGTGTCGGCACTGCTCGCGTCGATGCTGTCGCTGTCGCGGCTGTTCACACAGGAACACGAGGATGGCAGT
CTCGACCAGCTCCTGCTGTCACCCCACCCGCTGGCCTTGCTCGTGCTGGCCAAGATCGGCGCGCACTGGCTGACCAGCGG
CCTGCCGCTGCTCGTGCTGACGCCGCTGCTGGCCCAGCAATACAGCCTGCCGGCCGGCTCCGCGCTGCTGCTGTCGGCCT
CGCTGCTGGTGGGAACCCCTGCACTTAGCCTGATCGGCGCCGTTGGCGCGGCATTGACGCTGGGCGTACGCGGTGGCGCC
GTGCTGTTGTGCATCCTGGTGCTGCCGCTGTCAATTCCTGTGCTGGTGTTCGGCGCCAGCGCGGGCGCGGCGGCCGATGC
CGGACTCGACGTGATCCCGCAATTTTCGCTACTCGGGGCCTGCCTGGCGCTATCGCTGTTCCTGTGTCCGCTGGCCACGG
CGGCAGGCTTGCGCATCGCCATGGAGTAA

Upstream 100 bases:

>100_bases
CCGAGCACCTGCAGCGGGGCGGCATCGCCGTGGTCGCCACGCATCAGCGGCTGCCCGCCGAGGGTGCGGTGCTCGATCTC
GCCACAGACGCGGGTTCGCC

Downstream 100 bases:

>100_bases
CACGATGCAGCGCGACATTTCCCTCGACGCCAACGCCCATTCCCCACGCACCGCGCGGGCGCGCTGGCTGGCCTTTGCCG
CGCCAGTGCGCTTCTACCCG

Product: cytochrome C biogenesis protein; heme exporter protein

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycW [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MIQAIGTIIAHDLSIAWRRRTGLLSSLVFFVIATSLFPLAIGPDPQQLRALAPGILWVSALLASMLSLSRLFTQEHEDGS
LDQLLLSPHPLALLVLAKIGAHWLTSGLPLLVLTPLLAQQYSLPAGSALLLSASLLVGTPALSLIGAVGAALTLGVRGGA
VLLCILVLPLSIPVLVFGASAGAAADAGLDVIPQFSLLGACLALSLFLCPLATAAGLRIAME

Sequences:

>Translated_222_residues
MIQAIGTIIAHDLSIAWRRRTGLLSSLVFFVIATSLFPLAIGPDPQQLRALAPGILWVSALLASMLSLSRLFTQEHEDGS
LDQLLLSPHPLALLVLAKIGAHWLTSGLPLLVLTPLLAQQYSLPAGSALLLSASLLVGTPALSLIGAVGAALTLGVRGGA
VLLCILVLPLSIPVLVFGASAGAAADAGLDVIPQFSLLGACLALSLFLCPLATAAGLRIAME
>Mature_222_residues
MIQAIGTIIAHDLSIAWRRRTGLLSSLVFFVIATSLFPLAIGPDPQQLRALAPGILWVSALLASMLSLSRLFTQEHEDGS
LDQLLLSPHPLALLVLAKIGAHWLTSGLPLLVLTPLLAQQYSLPAGSALLLSASLLVGTPALSLIGAVGAALTLGVRGGA
VLLCILVLPLSIPVLVFGASAGAAADAGLDVIPQFSLLGACLALSLFLCPLATAAGLRIAME

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=211, Percent_Identity=49.2890995260664, Blast_Score=145, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 22771; Mature: 22771

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQAIGTIIAHDLSIAWRRRTGLLSSLVFFVIATSLFPLAIGPDPQQLRALAPGILWVSA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LLASMLSLSRLFTQEHEDGSLDQLLLSPHPLALLVLAKIGAHWLTSGLPLLVLTPLLAQQ
HHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
YSLPAGSALLLSASLLVGTPALSLIGAVGAALTLGVRGGAVLLCILVLPLSIPVLVFGAS
HCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECCC
AGAAADAGLDVIPQFSLLGACLALSLFLCPLATAAGLRIAME
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
>Mature Secondary Structure
MIQAIGTIIAHDLSIAWRRRTGLLSSLVFFVIATSLFPLAIGPDPQQLRALAPGILWVSA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LLASMLSLSRLFTQEHEDGSLDQLLLSPHPLALLVLAKIGAHWLTSGLPLLVLTPLLAQQ
HHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
YSLPAGSALLLSASLLVGTPALSLIGAVGAALTLGVRGGAVLLCILVLPLSIPVLVFGAS
HCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECCC
AGAAADAGLDVIPQFSLLGACLALSLFLCPLATAAGLRIAME
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]