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The map label for this gene is mmgC [H]

Identifier: 94312827

GI number: 94312827

Start: 443993

End: 445162

Strand: Reverse

Name: mmgC [H]

Synonym: Rmet_3899

Alternate gene names: 94312827

Gene position: 445162-443993 (Counterclockwise)

Preceding gene: 94312829

Following gene: 94312826

Centisome position: 17.25

GC content: 62.22

Gene sequence:

>1170_bases
ATGCATGCTGCACAGGACCAAGACCTGATTTACCCGGAAATCCGCGAGGCCGTACGCGACCTCTGCAAGCAATTCGATTC
GGCCTATTGGCAACGCATCGAGGAACACAGCGCATTTCCGGAGGAGTTCGTCCAGGCGCTGACCCACGCCGGCTGGCTGT
CCGCGCTGATTCCCGAGGCATACGGTGGCTCCGGCCTGCCGCTGACCGCAGCCTCCGTGATCATGGAAGAGATCAACCGC
AACGGCGGCAACTCGGGGGCGTGCCACGGTCAGATGTACGTGATGGGCTGCCTGCTGCGCCACGGCTCAGAGGCGCAGAA
GCAGCGCTGGCTGCCCGGCATCGCTTCGGGCGAGTTGCGCATGCAGTCGATGGCCGTGACCGAACCGACCACCGGTACCG
ATACCACCAAGCTCAAGACCACGGCAGTGCGGCGCGGCGACAAGTACGTGATCAACGGCCAGAAGGTCTGGATCTCGCGC
GTCCAGCATTCCGACCTGATGCTGCTGCTGGCACGCACCACGCCGCTGGACCAGGTGAAGAAGAAGTCCGAAGGTCTGTC
GGTGTTCGTCGTCGACTTGCGCGAAGCGATTGGCAACGGCCTGACGGTCCAGCCGATCCGCAACATGGTCAACCACGAAA
CCAATGAGCTGTTCTTCGATAACCTCGAAATCCCGGCCGAAAACCTGATTGGCGAGGAAGGCAAGGGACTCAAGTACATC
CTCGACGGCCTGAATGCCGAACGTATCCTGATTGCCGCCGAGTGCATCGGCGATGGCTACTGGTTCGTCGAACGCGCCAG
CAGCTACGCCCGCGAGCGGATCGTGTTCGATCGCCCGATCGGCCAGAACCAGGGCGTGCAGTTCCCGATCGCGCGTTCGT
TCGTCAATGTGGAAGCCGCCAGTCTGATGCGTTACAAGGCCGCCCAGCTGTTCGACGCAGGCAAGCCCTGCGGCAAGGAA
GCCAACATGGCGAAGCTGCTGGCCGCCGATGCTTCATGGGAAGCGGCCAACGTCTGCCTGCAGACGCACGGTGGATTCGG
CTTTGCCGCCGAGTACGACATCGAACGCAAGTTCCGTGAAACGCGCCTGTACCAGGTGGCGCCGATCTCGACCAACCTGA
TCCTGTCGTTCGTCGCCGAACACGTTCTCGAACTGCCCCGCTCGTTCTGA

Upstream 100 bases:

>100_bases
ATCCCTAAGCCGGAACCGAAGTCGCGCTTCCGCAAATGCGAATGTCACTGCTCCGACCGGTCGGGAATAATGCGCCTACT
CGATACTGACGGACATTGCC

Downstream 100 bases:

>100_bases
TACCTGCCATGTCCGACATCGATACCCGCTATCCGACCCGCCAGCTCTGCGAGTTTCTCGCGCGGTTCACGCTCGCCGAT
GTGCCGTCGCCCGTCGTCGA

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MHAAQDQDLIYPEIREAVRDLCKQFDSAYWQRIEEHSAFPEEFVQALTHAGWLSALIPEAYGGSGLPLTAASVIMEEINR
NGGNSGACHGQMYVMGCLLRHGSEAQKQRWLPGIASGELRMQSMAVTEPTTGTDTTKLKTTAVRRGDKYVINGQKVWISR
VQHSDLMLLLARTTPLDQVKKKSEGLSVFVVDLREAIGNGLTVQPIRNMVNHETNELFFDNLEIPAENLIGEEGKGLKYI
LDGLNAERILIAAECIGDGYWFVERASSYARERIVFDRPIGQNQGVQFPIARSFVNVEAASLMRYKAAQLFDAGKPCGKE
ANMAKLLAADASWEAANVCLQTHGGFGFAAEYDIERKFRETRLYQVAPISTNLILSFVAEHVLELPRSF

Sequences:

>Translated_389_residues
MHAAQDQDLIYPEIREAVRDLCKQFDSAYWQRIEEHSAFPEEFVQALTHAGWLSALIPEAYGGSGLPLTAASVIMEEINR
NGGNSGACHGQMYVMGCLLRHGSEAQKQRWLPGIASGELRMQSMAVTEPTTGTDTTKLKTTAVRRGDKYVINGQKVWISR
VQHSDLMLLLARTTPLDQVKKKSEGLSVFVVDLREAIGNGLTVQPIRNMVNHETNELFFDNLEIPAENLIGEEGKGLKYI
LDGLNAERILIAAECIGDGYWFVERASSYARERIVFDRPIGQNQGVQFPIARSFVNVEAASLMRYKAAQLFDAGKPCGKE
ANMAKLLAADASWEAANVCLQTHGGFGFAAEYDIERKFRETRLYQVAPISTNLILSFVAEHVLELPRSF
>Mature_389_residues
MHAAQDQDLIYPEIREAVRDLCKQFDSAYWQRIEEHSAFPEEFVQALTHAGWLSALIPEAYGGSGLPLTAASVIMEEINR
NGGNSGACHGQMYVMGCLLRHGSEAQKQRWLPGIASGELRMQSMAVTEPTTGTDTTKLKTTAVRRGDKYVINGQKVWISR
VQHSDLMLLLARTTPLDQVKKKSEGLSVFVVDLREAIGNGLTVQPIRNMVNHETNELFFDNLEIPAENLIGEEGKGLKYI
LDGLNAERILIAAECIGDGYWFVERASSYARERIVFDRPIGQNQGVQFPIARSFVNVEAASLMRYKAAQLFDAGKPCGKE
ANMAKLLAADASWEAANVCLQTHGGFGFAAEYDIERKFRETRLYQVAPISTNLILSFVAEHVLELPRSF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=30.7486631016043, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI4557233, Length=392, Percent_Identity=30.3571428571429, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI226958412, Length=361, Percent_Identity=28.808864265928, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI226958414, Length=331, Percent_Identity=30.2114803625378, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI21361497, Length=357, Percent_Identity=28.5714285714286, Blast_Score=151, Evalue=9e-37,
Organism=Homo sapiens, GI187960098, Length=351, Percent_Identity=29.6296296296296, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI4557231, Length=351, Percent_Identity=29.6296296296296, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI4501857, Length=373, Percent_Identity=27.3458445040214, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI4557235, Length=344, Percent_Identity=29.6511627906977, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI76496475, Length=344, Percent_Identity=29.6511627906977, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI7656849, Length=357, Percent_Identity=28.8515406162465, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI48976061, Length=282, Percent_Identity=27.6595744680851, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI211971008, Length=282, Percent_Identity=27.6595744680851, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI4503943, Length=353, Percent_Identity=25.2124645892351, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI7669494, Length=353, Percent_Identity=25.2124645892351, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI38505218, Length=291, Percent_Identity=26.8041237113402, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI87081958, Length=389, Percent_Identity=26.7352185089974, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1786223, Length=384, Percent_Identity=27.34375, Blast_Score=145, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI17534899, Length=343, Percent_Identity=33.2361516034985, Blast_Score=184, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI17570075, Length=384, Percent_Identity=30.7291666666667, Blast_Score=178, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17569725, Length=364, Percent_Identity=31.8681318681319, Blast_Score=177, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI17506239, Length=372, Percent_Identity=29.0322580645161, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17508101, Length=357, Percent_Identity=29.1316526610644, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17538396, Length=361, Percent_Identity=28.2548476454294, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI71985184, Length=355, Percent_Identity=29.5774647887324, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71990804, Length=296, Percent_Identity=33.1081081081081, Blast_Score=150, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI17505929, Length=348, Percent_Identity=29.3103448275862, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17551932, Length=341, Percent_Identity=28.1524926686217, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17533517, Length=358, Percent_Identity=26.8156424581006, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71985192, Length=316, Percent_Identity=29.1139240506329, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI32563615, Length=244, Percent_Identity=31.1475409836066, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17534353, Length=357, Percent_Identity=26.6106442577031, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17531909, Length=246, Percent_Identity=28.4552845528455, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17562446, Length=269, Percent_Identity=28.2527881040892, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71982178, Length=286, Percent_Identity=24.1258741258741, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17531913, Length=167, Percent_Identity=27.5449101796407, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI86563381, Length=275, Percent_Identity=28, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI86563383, Length=275, Percent_Identity=28, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=30.9333333333333, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24666513, Length=375, Percent_Identity=32, Blast_Score=168, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24646207, Length=378, Percent_Identity=29.3650793650794, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI281363737, Length=404, Percent_Identity=26.4851485148515, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21355753, Length=330, Percent_Identity=29.3939393939394, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24660351, Length=374, Percent_Identity=28.8770053475936, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI19920834, Length=291, Percent_Identity=27.1477663230241, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43242; Mature: 43242

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAAQDQDLIYPEIREAVRDLCKQFDSAYWQRIEEHSAFPEEFVQALTHAGWLSALIPEA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
YGGSGLPLTAASVIMEEINRNGGNSGACHGQMYVMGCLLRHGSEAQKQRWLPGIASGELR
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCEE
MQSMAVTEPTTGTDTTKLKTTAVRRGDKYVINGQKVWISRVQHSDLMLLLARTTPLDQVK
EHHEEECCCCCCCCCCHHHHHHHHCCCEEEECCCEEEEHHHCCCCEEEEEECCCCHHHHH
KKSEGLSVFVVDLREAIGNGLTVQPIRNMVNHETNELFFDNLEIPAENLIGEEGKGLKYI
HHCCCCEEEEEEHHHHHCCCCCHHHHHHHHCCCCCCEEECCCCCCHHHHCCCCCCCHHHH
LDGLNAERILIAAECIGDGYWFVERASSYARERIVFDRPIGQNQGVQFPIARSFVNVEAA
HCCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHH
SLMRYKAAQLFDAGKPCGKEANMAKLLAADASWEAANVCLQTHGGFGFAAEYDIERKFRE
HHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCHHHHEEEEECCCCCEEEECCHHHHHHH
TRLYQVAPISTNLILSFVAEHVLELPRSF
HHCEEEECCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHAAQDQDLIYPEIREAVRDLCKQFDSAYWQRIEEHSAFPEEFVQALTHAGWLSALIPEA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
YGGSGLPLTAASVIMEEINRNGGNSGACHGQMYVMGCLLRHGSEAQKQRWLPGIASGELR
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCEE
MQSMAVTEPTTGTDTTKLKTTAVRRGDKYVINGQKVWISRVQHSDLMLLLARTTPLDQVK
EHHEEECCCCCCCCCCHHHHHHHHCCCEEEECCCEEEEHHHCCCCEEEEEECCCCHHHHH
KKSEGLSVFVVDLREAIGNGLTVQPIRNMVNHETNELFFDNLEIPAENLIGEEGKGLKYI
HHCCCCEEEEEEHHHHHCCCCCHHHHHHHHCCCCCCEEECCCCCCHHHHCCCCCCCHHHH
LDGLNAERILIAAECIGDGYWFVERASSYARERIVFDRPIGQNQGVQFPIARSFVNVEAA
HCCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHH
SLMRYKAAQLFDAGKPCGKEANMAKLLAADASWEAANVCLQTHGGFGFAAEYDIERKFRE
HHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCHHHHEEEEECCCCCEEEECCHHHHHHH
TRLYQVAPISTNLILSFVAEHVLELPRSF
HHCEEEECCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]