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The map label for this gene is lipA [H]

Identifier: 94312726

GI number: 94312726

Start: 334867

End: 336000

Strand: Reverse

Name: lipA [H]

Synonym: Rmet_3796

Alternate gene names: 94312726

Gene position: 336000-334867 (Counterclockwise)

Preceding gene: 94312729

Following gene: 94312725

Centisome position: 13.02

GC content: 65.43

Gene sequence:

>1134_bases
ATGGAACACGGCAATCGTCGTGGGCCCGGCCGGGCTTGCGCGCATCAGGACACCGTCACGCTGAAGGCAGGGACACGCAG
GTCCACAAGCGCCATCGCGAGGACTGCGGCGGGAACTGCGGCGGCCATCGCCGCAGCCATCGCCATGGCCTGGCCAGCCA
GTGCCACGGCCAGCAGCGACTATGCAAAGACACGCTATCCGATCGTGCTGGTGCATGGTCTGACCGGCGCGGCAAAGATG
GGCGGCGTGATCGACTACTGGTACGGCATTCCCGAAGTGCTGCGGGCCAATGGCGCCACGGTCTACGTGTCCACGGTGCC
GTCGTTCAACAGCGATGAAGAACGCGCGCTGGCACTGCAGGCCTATGTACGCGCGGTCAAGCTGGAAACCGGCGCCGACA
AGGTCAATCTGATCGGACACAGCCAGGGCGGGCCCACCTCGCGGATGCTGGCTGCAATGTCGCCGCAGGATGTGGCATCG
GTGACGACTATCGGTAGCCCGCACCGCGGCAGCCAGCTCGCCGACGTCGTGCTGGACGTCATCAACGGCATCAGCAGCAT
TCCACTTGCGGGGCCGGCGCTGGTCAACGTGATTCAGGGCGTAACGAATCTCCTGGGCTGGTTCAATGGCCTGTTCAATG
GACAGGCGCTGAACCAGGATGCGATTGCCTCTGCGCGCACCCTGACCAGCCAGGGCGCCACCGAGCAGAACGCGCGGCTC
AACGCCACCCTGGCGCCTGGCTCGCAATCCGCGCTAGGCCCGGATTGCGACACCCCGGGAGCAGTCGCCGAGCAACGGCA
GGGGCGCGATGCCAGCGGAAAGCTCGTCACCTACACCCAGGCCGCTTACTCCTGGACCGGCCGGGGCGGCCCGATCAACC
TGCTGCGCTCGAACCTGCTTGACCCATCCACGGCGGCCATGGCCGCCGCTGCCGGTGTCATGGGCATGAAGGGCGCCGGC
CCCAACGACGGGATGGTGTCGGTGTGCAGCGCCAAGTGGGGACGCGTGCTTTCCACCGACTACTACTGGAACCATCTCGA
CGAGATCAATCAGATGCTCGGTATGTATCAGGACGTCGACCCACGCACGGTGATCCTGAATCACGCCAACCGCTTGCGCA
ATGATCAGCTCTGA

Upstream 100 bases:

>100_bases
GTGTGTTTGGAGGAAACCGCCTAAGGTTTTGATTGTGCTCGCAAAGTCAGGTGTCTTTACTGTTTCAAACAAAAAATGAT
TCCACCACCGAGGAGACTAG

Downstream 100 bases:

>100_bases
GCGAAGGCCAGGGGTCACCCTGGTCCTGGTAGTAGCCGGGCTCGTGGGTGCCGCCGTCTATTGGGCAACGGCACCCACGG
AACCGGCGCAAGGTCCACTG

Product: triacylglycerol lipase

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MEHGNRRGPGRACAHQDTVTLKAGTRRSTSAIARTAAGTAAAIAAAIAMAWPASATASSDYAKTRYPIVLVHGLTGAAKM
GGVIDYWYGIPEVLRANGATVYVSTVPSFNSDEERALALQAYVRAVKLETGADKVNLIGHSQGGPTSRMLAAMSPQDVAS
VTTIGSPHRGSQLADVVLDVINGISSIPLAGPALVNVIQGVTNLLGWFNGLFNGQALNQDAIASARTLTSQGATEQNARL
NATLAPGSQSALGPDCDTPGAVAEQRQGRDASGKLVTYTQAAYSWTGRGGPINLLRSNLLDPSTAAMAAAAGVMGMKGAG
PNDGMVSVCSAKWGRVLSTDYYWNHLDEINQMLGMYQDVDPRTVILNHANRLRNDQL

Sequences:

>Translated_377_residues
MEHGNRRGPGRACAHQDTVTLKAGTRRSTSAIARTAAGTAAAIAAAIAMAWPASATASSDYAKTRYPIVLVHGLTGAAKM
GGVIDYWYGIPEVLRANGATVYVSTVPSFNSDEERALALQAYVRAVKLETGADKVNLIGHSQGGPTSRMLAAMSPQDVAS
VTTIGSPHRGSQLADVVLDVINGISSIPLAGPALVNVIQGVTNLLGWFNGLFNGQALNQDAIASARTLTSQGATEQNARL
NATLAPGSQSALGPDCDTPGAVAEQRQGRDASGKLVTYTQAAYSWTGRGGPINLLRSNLLDPSTAAMAAAAGVMGMKGAG
PNDGMVSVCSAKWGRVLSTDYYWNHLDEINQMLGMYQDVDPRTVILNHANRLRNDQL
>Mature_377_residues
MEHGNRRGPGRACAHQDTVTLKAGTRRSTSAIARTAAGTAAAIAAAIAMAWPASATASSDYAKTRYPIVLVHGLTGAAKM
GGVIDYWYGIPEVLRANGATVYVSTVPSFNSDEERALALQAYVRAVKLETGADKVNLIGHSQGGPTSRMLAAMSPQDVAS
VTTIGSPHRGSQLADVVLDVINGISSIPLAGPALVNVIQGVTNLLGWFNGLFNGQALNQDAIASARTLTSQGATEQNARL
NATLAPGSQSALGPDCDTPGAVAEQRQGRDASGKLVTYTQAAYSWTGRGGPINLLRSNLLDPSTAAMAAAAGVMGMKGAG
PNDGMVSVCSAKWGRVLSTDYYWNHLDEINQMLGMYQDVDPRTVILNHANRLRNDQL

Specific function: Catalyzes the hydrolysis of triglycerides [H]

COG id: COG1075

COG function: function code R; Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Pseudomonas lipase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320263, Length=203, Percent_Identity=30.0492610837438, Blast_Score=90, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 39343; Mature: 39343

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHGNRRGPGRACAHQDTVTLKAGTRRSTSAIARTAAGTAAAIAAAIAMAWPASATASSD
CCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
YAKTRYPIVLVHGLTGAAKMGGVIDYWYGIPEVLRANGATVYVSTVPSFNSDEERALALQ
CHHCCCCEEEEECCCCHHHHCCHHHHHHCCHHHHHCCCCEEEEEECCCCCCCHHHHHHHH
AYVRAVKLETGADKVNLIGHSQGGPTSRMLAAMSPQDVASVTTIGSPHRGSQLADVVLDV
HHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHH
INGISSIPLAGPALVNVIQGVTNLLGWFNGLFNGQALNQDAIASARTLTSQGATEQNARL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEE
NATLAPGSQSALGPDCDTPGAVAEQRQGRDASGKLVTYTQAAYSWTGRGGPINLLRSNLL
EEEECCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEHHHEEECCCCCCHHHHHHHCC
DPSTAAMAAAAGVMGMKGAGPNDGMVSVCSAKWGRVLSTDYYWNHLDEINQMLGMYQDVD
CCHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHCCCEEECCHHHHHHHHHHHHHHHHCCCC
PRTVILNHANRLRNDQL
CCEEEEHHHHHHCCCCC
>Mature Secondary Structure
MEHGNRRGPGRACAHQDTVTLKAGTRRSTSAIARTAAGTAAAIAAAIAMAWPASATASSD
CCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
YAKTRYPIVLVHGLTGAAKMGGVIDYWYGIPEVLRANGATVYVSTVPSFNSDEERALALQ
CHHCCCCEEEEECCCCHHHHCCHHHHHHCCHHHHHCCCCEEEEEECCCCCCCHHHHHHHH
AYVRAVKLETGADKVNLIGHSQGGPTSRMLAAMSPQDVASVTTIGSPHRGSQLADVVLDV
HHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHH
INGISSIPLAGPALVNVIQGVTNLLGWFNGLFNGQALNQDAIASARTLTSQGATEQNARL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEE
NATLAPGSQSALGPDCDTPGAVAEQRQGRDASGKLVTYTQAAYSWTGRGGPINLLRSNLL
EEEECCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEHHHEEECCCCCCHHHHHHHCC
DPSTAAMAAAAGVMGMKGAGPNDGMVSVCSAKWGRVLSTDYYWNHLDEINQMLGMYQDVD
CCHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHCCCEEECCHHHHHHHHHHHHHHHHCCCC
PRTVILNHANRLRNDQL
CCEEEEHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1987151; 9032073; 9032074 [H]