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The map label for this gene is rssA [H]

Identifier: 94312515

GI number: 94312515

Start: 3890851

End: 3892338

Strand: Reverse

Name: rssA [H]

Synonym: Rmet_3584

Alternate gene names: 94312515

Gene position: 3892338-3890851 (Counterclockwise)

Preceding gene: 94312516

Following gene: 94312508

Centisome position: 99.09

GC content: 68.82

Gene sequence:

>1488_bases
ATGTGGCCTCGCCGCCTGCGCCAGCGCGCGCGCCTGCCTGTGCGGTCCTGGTTGCGCGGCAGCCTGCGGCGCCAGTTGCT
GATCCTGCTGGTGCCGGCGCTGGCGCTCATGATGGCGGTCGATACGTGGTTCACCTACGGCACCCTGCGCGATGCCGCCA
ACACGGCATACGACCGCTCGCTGTACGGCTCCGTGCTGACCATCGACAACGCCATCGGGATGGCCGGCGAAAGCATCCAG
CTATCGCTGCCCGACGCAGCCATGGAGATGTTCGAGACCGCGGCGCAGACACACGTGTTCTACCGCGTGTCGATGGAGCG
GGCGGGCCAGATCGAGACTGTCACCGGTTATGACGACCTGCCGCTGCCGGCGGGAGCGCTGCGGAACGGCCAACCGCGCT
TCTACGACGCCACCTATCGCGGCGACCGGGTCCGCATCGCGGCGATGGCCCGCCCGGTCTATCGCCCCGACGCGCACATG
CGCGTGATCATCCAGGTGGCGGAGACCGCCGAGCCGCGCGCGGCGCTGATCGGCAACGTCTGGCGCAGTGCACTGCTGCG
CGACATCGCGCTGATCATCGTCTCGGCGCTGATCCTGGTCGGCGGCATTACCTACGTGCTCCGCCCGCTGCAACAGGTAC
GCGACGATGTGCGCGCGCGCTCGCCCGAGGATCTGACCCCGCTCGAATTCGACCATGTGCCGGTCGAGGTGCGCCCGCTG
GTCGACGCGGTGAACCTGCACGTGTCGCGCTCCGACGCGATGGCCCAGGCCCAGGCCCAGTTCATCGCCGATGCCGCCCA
TCAGCTCCGCACGCCACTGGCCATCCTGAAGACACAGGCCGAGTTCGCGCAGCGGCAGCTCGACACGTTCGGCGGTGAAG
GCGCGGCGCATTCAGGCGCCGCCGAAGCCGTTGGCGGCATCGTCAAGCAACTGGAGCAGGCCGCGCGGATGACCAACCAG
TTGCTGGCACTGGCGCGCGTCAGACAGCACGCGCCGGACGGCACCGCCCCGGCCACGGAAGTGGAAATCATCGACGCAAT
CGGCGTGGCGGAGCAGGTGGCACTGGACTACCTGCCACTCGCTCGCGGACGCCAGCAGGATTTCGGCTGGGAACGACCGG
CCGGACTGGAACTGCCAGTGCAGGCCGATCCCGCGCTGTTGCGCGAGGCATTCGCCAATCTTGTCCACAACGCCATCCAG
TACTCGGGACGCCGCAGCCGCATCACGCTCTCCGCCACACAGGTCGACGACAGCGCCATGCTCGTCGTCGAGGATGACGG
CCCCGGCATTCCCGAGGCCGAACGCGAGAAGGTGTTCGCGCGCTTCTATCGCCGGGTCGGCCACACGGAAACAGGGTCGG
GCCTCGGACTTGCCATCTCGCGCGAGATGGCGATGCGCTGCGGCGGCACCGTGGTCTTGCGCGAAGGCGTCCAGGGACGC
GGCGTGCGCGCGGAACTCAGCTTGCCACTGGTGATGCCGACGGCCTGA

Upstream 100 bases:

>100_bases
TGCTGGTCTATCGCCTGCGCAAGAAGCTGTCCGGCCACGGCGTAACCATCGTCACGCTACGCGGCTTCGGCTACCTGCTC
GAACCAGAGACCGCCACCTG

Downstream 100 bases:

>100_bases
TGGGCCGCGCACGCCGACTCATTGCTACTTCTTCATCACCGCATCGGTACATGGGTCGGGACGATCCACGGCAGGGACAC
GCACAAGCACATCGAATGCC

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MWPRRLRQRARLPVRSWLRGSLRRQLLILLVPALALMMAVDTWFTYGTLRDAANTAYDRSLYGSVLTIDNAIGMAGESIQ
LSLPDAAMEMFETAAQTHVFYRVSMERAGQIETVTGYDDLPLPAGALRNGQPRFYDATYRGDRVRIAAMARPVYRPDAHM
RVIIQVAETAEPRAALIGNVWRSALLRDIALIIVSALILVGGITYVLRPLQQVRDDVRARSPEDLTPLEFDHVPVEVRPL
VDAVNLHVSRSDAMAQAQAQFIADAAHQLRTPLAILKTQAEFAQRQLDTFGGEGAAHSGAAEAVGGIVKQLEQAARMTNQ
LLALARVRQHAPDGTAPATEVEIIDAIGVAEQVALDYLPLARGRQQDFGWERPAGLELPVQADPALLREAFANLVHNAIQ
YSGRRSRITLSATQVDDSAMLVVEDDGPGIPEAEREKVFARFYRRVGHTETGSGLGLAISREMAMRCGGTVVLREGVQGR
GVRAELSLPLVMPTA

Sequences:

>Translated_495_residues
MWPRRLRQRARLPVRSWLRGSLRRQLLILLVPALALMMAVDTWFTYGTLRDAANTAYDRSLYGSVLTIDNAIGMAGESIQ
LSLPDAAMEMFETAAQTHVFYRVSMERAGQIETVTGYDDLPLPAGALRNGQPRFYDATYRGDRVRIAAMARPVYRPDAHM
RVIIQVAETAEPRAALIGNVWRSALLRDIALIIVSALILVGGITYVLRPLQQVRDDVRARSPEDLTPLEFDHVPVEVRPL
VDAVNLHVSRSDAMAQAQAQFIADAAHQLRTPLAILKTQAEFAQRQLDTFGGEGAAHSGAAEAVGGIVKQLEQAARMTNQ
LLALARVRQHAPDGTAPATEVEIIDAIGVAEQVALDYLPLARGRQQDFGWERPAGLELPVQADPALLREAFANLVHNAIQ
YSGRRSRITLSATQVDDSAMLVVEDDGPGIPEAEREKVFARFYRRVGHTETGSGLGLAISREMAMRCGGTVVLREGVQGR
GVRAELSLPLVMPTA
>Mature_495_residues
MWPRRLRQRARLPVRSWLRGSLRRQLLILLVPALALMMAVDTWFTYGTLRDAANTAYDRSLYGSVLTIDNAIGMAGESIQ
LSLPDAAMEMFETAAQTHVFYRVSMERAGQIETVTGYDDLPLPAGALRNGQPRFYDATYRGDRVRIAAMARPVYRPDAHM
RVIIQVAETAEPRAALIGNVWRSALLRDIALIIVSALILVGGITYVLRPLQQVRDDVRARSPEDLTPLEFDHVPVEVRPL
VDAVNLHVSRSDAMAQAQAQFIADAAHQLRTPLAILKTQAEFAQRQLDTFGGEGAAHSGAAEAVGGIVKQLEQAARMTNQ
LLALARVRQHAPDGTAPATEVEIIDAIGVAEQVALDYLPLARGRQQDFGWERPAGLELPVQADPALLREAFANLVHNAIQ
YSGRRSRITLSATQVDDSAMLVVEDDGPGIPEAEREKVFARFYRRVGHTETGSGLGLAISREMAMRCGGTVVLREGVQGR
GVRAELSLPLVMPTA

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790551, Length=301, Percent_Identity=30.2325581395349, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1789403, Length=343, Percent_Identity=32.6530612244898, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786783, Length=290, Percent_Identity=28.6206896551724, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1788279, Length=314, Percent_Identity=27.0700636942675, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786912, Length=224, Percent_Identity=29.4642857142857, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1786600, Length=266, Percent_Identity=28.9473684210526, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790861, Length=344, Percent_Identity=29.6511627906977, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788393, Length=291, Percent_Identity=27.1477663230241, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790346, Length=255, Percent_Identity=27.0588235294118, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787374, Length=314, Percent_Identity=27.7070063694268, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787894, Length=272, Percent_Identity=27.9411764705882, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789808, Length=266, Percent_Identity=27.8195488721804, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI48994928, Length=257, Percent_Identity=27.2373540856031, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788549, Length=247, Percent_Identity=25.1012145748988, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54254; Mature: 54254

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWPRRLRQRARLPVRSWLRGSLRRQLLILLVPALALMMAVDTWFTYGTLRDAANTAYDRS
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGSVLTIDNAIGMAGESIQLSLPDAAMEMFETAAQTHVFYRVSMERAGQIETVTGYDDL
HCCCCEEECHHHCCCCCCEEEECCHHHHHHHHHHHHHHEEEEEEHHHCCCEEEECCCCCC
PLPAGALRNGQPRFYDATYRGDRVRIAAMARPVYRPDAHMRVIIQVAETAEPRAALIGNV
CCCHHHCCCCCCCEEEEECCCCEEEEEEHHCCCCCCCCCCEEEEEEHHCCCCHHHHHHHH
WRSALLRDIALIIVSALILVGGITYVLRPLQQVRDDVRARSPEDLTPLEFDHVPVEVRPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHH
VDAVNLHVSRSDAMAQAQAQFIADAAHQLRTPLAILKTQAEFAQRQLDTFGGEGAAHSGA
HHHHHHEECCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCH
AEAVGGIVKQLEQAARMTNQLLALARVRQHAPDGTAPATEVEIIDAIGVAEQVALDYLPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
ARGRQQDFGWERPAGLELPVQADPALLREAFANLVHNAIQYSGRRSRITLSATQVDDSAM
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCEE
LVVEDDGPGIPEAEREKVFARFYRRVGHTETGSGLGLAISREMAMRCGGTVVLREGVQGR
EEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHCCCEEEEECCCCCC
GVRAELSLPLVMPTA
CEEEEEECCEEECCC
>Mature Secondary Structure
MWPRRLRQRARLPVRSWLRGSLRRQLLILLVPALALMMAVDTWFTYGTLRDAANTAYDRS
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGSVLTIDNAIGMAGESIQLSLPDAAMEMFETAAQTHVFYRVSMERAGQIETVTGYDDL
HCCCCEEECHHHCCCCCCEEEECCHHHHHHHHHHHHHHEEEEEEHHHCCCEEEECCCCCC
PLPAGALRNGQPRFYDATYRGDRVRIAAMARPVYRPDAHMRVIIQVAETAEPRAALIGNV
CCCHHHCCCCCCCEEEEECCCCEEEEEEHHCCCCCCCCCCEEEEEEHHCCCCHHHHHHHH
WRSALLRDIALIIVSALILVGGITYVLRPLQQVRDDVRARSPEDLTPLEFDHVPVEVRPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHH
VDAVNLHVSRSDAMAQAQAQFIADAAHQLRTPLAILKTQAEFAQRQLDTFGGEGAAHSGA
HHHHHHEECCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCH
AEAVGGIVKQLEQAARMTNQLLALARVRQHAPDGTAPATEVEIIDAIGVAEQVALDYLPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
ARGRQQDFGWERPAGLELPVQADPALLREAFANLVHNAIQYSGRRSRITLSATQVDDSAM
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCEE
LVVEDDGPGIPEAEREKVFARFYRRVGHTETGSGLGLAISREMAMRCGGTVVLREGVQGR
EEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHCCCEEEEECCCCCC
GVRAELSLPLVMPTA
CEEEEEECCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA