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The map label for this gene is tctD [H]

Identifier: 94312516

GI number: 94312516

Start: 3892338

End: 3893012

Strand: Reverse

Name: tctD [H]

Synonym: Rmet_3585

Alternate gene names: 94312516

Gene position: 3893012-3892338 (Counterclockwise)

Preceding gene: 94312518

Following gene: 94312515

Centisome position: 99.11

GC content: 67.41

Gene sequence:

>675_bases
ATGCGCATCCTGCTGGTGGAAGATGAAGTGGAACTGGCCCGCTGGGTCACACGCGCACTTGAGCAGGGCGGCTTCGTGAT
CGAGCATGTCACCGACGGCCTGAAGGCCGAGGCCCGCCTCATGGCCGAGGAATACGATGCCGTCGTGCTGGACCTGCGCC
TTCCCGGCAAGGACGGCCTGGCCGTGCTGAAGGCCATGCGCGGCCGCGACGACCGCACGCCCGTGCTGATCCTCACCGCA
CAGGACACCCTGGATGAACGCGTGCGCGGTCTCAATCTCGGGGCCGACGACTACCTGCCCAAACCATTCGCCATCGCGGA
ACTCGAGGCCCGTATCCTGGCGCTGATCCGGCGCAGCCGTGGCCGGGCGCATCCGCGCCTGCAATGCGGCACGCTGGTAT
TCGACGGCGAAGCGCGCAGCTTCACACTGGCTGGCGCGCCGCTGTCCCTGACCCCGCGCGAATCGACGCTGCTCGGCGCG
CTGCTGGCCCGAAGCGGCCAACCGCTGACGAAAGCCCAATTGCTCGACAAGGTGTTCTCGCTCGACGCGGACGTGAGCCC
GGACGCCATCGAGGTGCTGGTCTATCGCCTGCGCAAGAAGCTGTCCGGCCACGGCGTAACCATCGTCACGCTACGCGGCT
TCGGCTACCTGCTCGAACCAGAGACCGCCACCTGA

Upstream 100 bases:

>100_bases
GTGCGAGCGGCGCCCCCGACACCCGCCGCCGAGGCGGTATCATAGGCGCCCTCGGGGGCAGCCCCCGGAGACAGATCAAG
AGCGGGCAGAGGAGGGTCCC

Downstream 100 bases:

>100_bases
TGTGGCCTCGCCGCCTGCGCCAGCGCGCGCGCCTGCCTGTGCGGTCCTGGTTGCGCGGCAGCCTGCGGCGCCAGTTGCTG
ATCCTGCTGGTGCCGGCGCT

Product: putative two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MRILLVEDEVELARWVTRALEQGGFVIEHVTDGLKAEARLMAEEYDAVVLDLRLPGKDGLAVLKAMRGRDDRTPVLILTA
QDTLDERVRGLNLGADDYLPKPFAIAELEARILALIRRSRGRAHPRLQCGTLVFDGEARSFTLAGAPLSLTPRESTLLGA
LLARSGQPLTKAQLLDKVFSLDADVSPDAIEVLVYRLRKKLSGHGVTIVTLRGFGYLLEPETAT

Sequences:

>Translated_224_residues
MRILLVEDEVELARWVTRALEQGGFVIEHVTDGLKAEARLMAEEYDAVVLDLRLPGKDGLAVLKAMRGRDDRTPVLILTA
QDTLDERVRGLNLGADDYLPKPFAIAELEARILALIRRSRGRAHPRLQCGTLVFDGEARSFTLAGAPLSLTPRESTLLGA
LLARSGQPLTKAQLLDKVFSLDADVSPDAIEVLVYRLRKKLSGHGVTIVTLRGFGYLLEPETAT
>Mature_224_residues
MRILLVEDEVELARWVTRALEQGGFVIEHVTDGLKAEARLMAEEYDAVVLDLRLPGKDGLAVLKAMRGRDDRTPVLILTA
QDTLDERVRGLNLGADDYLPKPFAIAELEARILALIRRSRGRAHPRLQCGTLVFDGEARSFTLAGAPLSLTPRESTLLGA
LLARSGQPLTKAQLLDKVFSLDADVSPDAIEVLVYRLRKKLSGHGVTIVTLRGFGYLLEPETAT

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=44.4954128440367, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=41.2844036697248, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=37.8378378378378, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=35.3211009174312, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=30.4347826086957, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=35.7466063348416, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=36.6812227074236, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=32.1266968325792, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=32.8828828828829, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=29.5154185022026, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=30.6666666666667, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=28.6324786324786, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=28.82096069869, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1790299, Length=125, Percent_Identity=37.6, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=37.6146788990826, Blast_Score=72, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322000, Length=117, Percent_Identity=28.2051282051282, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24592; Mature: 24592

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLVEDEVELARWVTRALEQGGFVIEHVTDGLKAEARLMAEEYDAVVLDLRLPGKDGL
CEEEEECCHHHHHHHHHHHHHHCCEEEEHHHCCHHHHHHHHHHCCCEEEEEEECCCCCHH
AVLKAMRGRDDRTPVLILTAQDTLDERVRGLNLGADDYLPKPFAIAELEARILALIRRSR
HHHHHHHCCCCCCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GRAHPRLQCGTLVFDGEARSFTLAGAPLSLTPRESTLLGALLARSGQPLTKAQLLDKVFS
CCCCCCEEECEEEECCCCCEEEEECCCEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
LDADVSPDAIEVLVYRLRKKLSGHGVTIVTLRGFGYLLEPETAT
CCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEECCCCCC
>Mature Secondary Structure
MRILLVEDEVELARWVTRALEQGGFVIEHVTDGLKAEARLMAEEYDAVVLDLRLPGKDGL
CEEEEECCHHHHHHHHHHHHHHCCEEEEHHHCCHHHHHHHHHHCCCEEEEEEECCCCCHH
AVLKAMRGRDDRTPVLILTAQDTLDERVRGLNLGADDYLPKPFAIAELEARILALIRRSR
HHHHHHHCCCCCCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GRAHPRLQCGTLVFDGEARSFTLAGAPLSLTPRESTLLGALLARSGQPLTKAQLLDKVFS
CCCCCCEEECEEEECCCCCEEEEECCCEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
LDADVSPDAIEVLVYRLRKKLSGHGVTIVTLRGFGYLLEPETAT
CCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]