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The map label for this gene is htpX [H]

Identifier: 94312494

GI number: 94312494

Start: 3864906

End: 3865766

Strand: Reverse

Name: htpX [H]

Synonym: Rmet_3563

Alternate gene names: 94312494

Gene position: 3865766-3864906 (Counterclockwise)

Preceding gene: 94312495

Following gene: 94312493

Centisome position: 98.41

GC content: 66.09

Gene sequence:

>861_bases
ATGTTCAACTGGGTCAAGACCTTCATGCTGATGGCCGCGATCACGGCGCTGTTCGTTGTGATCGGCGGCATGATCGGCGG
ACGCAACGGCATGACATTCGCCCTGCTGATCGCGCTCGGCATGAACTTCTTCTCCTACTGGTTCTCGGACAAGATGGTCC
TGCGCATGTACAACGCGCAGGAAGTGGATGCCAGCACCGCGCCGCAGTTCTACAACATGGTGCACGAGCTTTCGCAGCGT
GCCGGCCTGCCGATGCCGCGCGTGTACCTGATCAACGAGGACGCGCCAAACGCGTTTGCCACGGGCCGCAATCCCGAGCA
CGCGGCGGTGGCCGCCACCACGGGCATCCTGCGGGTGCTGTCGGACCGCGAACTGCGCGGCGTGATGGCCCACGAACTCG
CGCACGTGAAGCATCGCGACATCCTGACCTCGACCATCGCCGCGACGATGGCCGGCGCCATTTCCGCGCTGGCCAATATG
GCGATGTTCTTCGGCGGGCGCGACGAGAACGGCAACCGCTCGAATCCGATTGCCGCCATCGCCGTGGCGATCCTGGCGCC
GCTGGCGGCATCATTGATCCAGATGGCGATCTCGCGGGCCCGCGAATTCGAGGCCGACCGCGGCGGCGCGGAGATCAGCG
GAGACCCGCAGGCCCTGGCCAGCGCGCTCGACAAGATCCATCGCTACGCCCAGGGCATTCCGTTCCAGGCCGCCGAGGAG
CATCCGGCCACGGCGCAGATGATGATCATGAATCCGCTCTCGGGCGGCGGGATCGCGAACCTGTTCTCGACCCACCCCGC
CACGGAGGAACGGATCGCGCGCCTGATGCAGATGGCGCAGACCGGCACCTACCCGGCCTGA

Upstream 100 bases:

>100_bases
CCTCCGGCATTGAATTTCCACGGTTCGCACCCTATCTAACCGTTATCGTGTCCACGCAGGGGCGTGGCACGCGACTGACA
GACGATCTGGAGATCAAGCC

Downstream 100 bases:

>100_bases
CGCGCATTGCCACGTTTCCGGGGGCTCATGCCAGGTAACGGGTAAACTGCCCGCTGTGTTCCGTCAGGAGCCGGCGGGCT
TTTTCGTATCCGCACGCGCC

Product: M48 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MFNWVKTFMLMAAITALFVVIGGMIGGRNGMTFALLIALGMNFFSYWFSDKMVLRMYNAQEVDASTAPQFYNMVHELSQR
AGLPMPRVYLINEDAPNAFATGRNPEHAAVAATTGILRVLSDRELRGVMAHELAHVKHRDILTSTIAATMAGAISALANM
AMFFGGRDENGNRSNPIAAIAVAILAPLAASLIQMAISRAREFEADRGGAEISGDPQALASALDKIHRYAQGIPFQAAEE
HPATAQMMIMNPLSGGGIANLFSTHPATEERIARLMQMAQTGTYPA

Sequences:

>Translated_286_residues
MFNWVKTFMLMAAITALFVVIGGMIGGRNGMTFALLIALGMNFFSYWFSDKMVLRMYNAQEVDASTAPQFYNMVHELSQR
AGLPMPRVYLINEDAPNAFATGRNPEHAAVAATTGILRVLSDRELRGVMAHELAHVKHRDILTSTIAATMAGAISALANM
AMFFGGRDENGNRSNPIAAIAVAILAPLAASLIQMAISRAREFEADRGGAEISGDPQALASALDKIHRYAQGIPFQAAEE
HPATAQMMIMNPLSGGGIANLFSTHPATEERIARLMQMAQTGTYPA
>Mature_286_residues
MFNWVKTFMLMAAITALFVVIGGMIGGRNGMTFALLIALGMNFFSYWFSDKMVLRMYNAQEVDASTAPQFYNMVHELSQR
AGLPMPRVYLINEDAPNAFATGRNPEHAAVAATTGILRVLSDRELRGVMAHELAHVKHRDILTSTIAATMAGAISALANM
AMFFGGRDENGNRSNPIAAIAVAILAPLAASLIQMAISRAREFEADRGGAEISGDPQALASALDKIHRYAQGIPFQAAEE
HPATAQMMIMNPLSGGGIANLFSTHPATEERIARLMQMAQTGTYPA

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=269, Percent_Identity=32.7137546468402, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 30833; Mature: 30833

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.0 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNWVKTFMLMAAITALFVVIGGMIGGRNGMTFALLIALGMNFFSYWFSDKMVLRMYNAQ
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCH
EVDASTAPQFYNMVHELSQRAGLPMPRVYLINEDAPNAFATGRNPEHAAVAATTGILRVL
HCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
SDRELRGVMAHELAHVKHRDILTSTIAATMAGAISALANMAMFFGGRDENGNRSNPIAAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AVAILAPLAASLIQMAISRAREFEADRGGAEISGDPQALASALDKIHRYAQGIPFQAAEE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
HPATAQMMIMNPLSGGGIANLFSTHPATEERIARLMQMAQTGTYPA
CCCCEEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MFNWVKTFMLMAAITALFVVIGGMIGGRNGMTFALLIALGMNFFSYWFSDKMVLRMYNAQ
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCH
EVDASTAPQFYNMVHELSQRAGLPMPRVYLINEDAPNAFATGRNPEHAAVAATTGILRVL
HCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
SDRELRGVMAHELAHVKHRDILTSTIAATMAGAISALANMAMFFGGRDENGNRSNPIAAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AVAILAPLAASLIQMAISRAREFEADRGGAEISGDPQALASALDKIHRYAQGIPFQAAEE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
HPATAQMMIMNPLSGGGIANLFSTHPATEERIARLMQMAQTGTYPA
CCCCEEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA