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The map label for this gene is sun [H]

Identifier: 94312493

GI number: 94312493

Start: 3863387

End: 3864760

Strand: Reverse

Name: sun [H]

Synonym: Rmet_3562

Alternate gene names: 94312493

Gene position: 3864760-3863387 (Counterclockwise)

Preceding gene: 94312494

Following gene: 94312492

Centisome position: 98.39

GC content: 67.25

Gene sequence:

>1374_bases
ATGCGCCTGCCACCAGATTCCCTTGCCTTCCAGATGCTCGGCGCCGCCGCTGCAGTACGCGGCGTCCATGAAGGCACGGC
CCTGCCGCAAGCCATCGAGGACGCCACCAACCTGCTGCGCCTGGACCGCGTGCGCGATGCCGCGACGCGCGGCGCCATCC
AGGACCTGGCCTATCGCACCGTGCGGCAGTTCGGCGCCACACGCGCCCTGGTGACGCAACTGGTCACACGCCCGCCCGGC
GCGCTGGTCGACTCCCTGCTGGCCGTGGCGCTCGCGCTGCTGCTCGAAGGCGAGGAGGGCGATCGGAGCAAGGTCGGACG
CGGCGGCTACTCCGACTTCACCGTCGTCGATCAGGCCGTCAGCGCGGCGGCCTCGGAGCCAAAGACCGCCCACGCGCGCG
GGCTCGTCAACGCAGTACTGCGCCGGTTCCTGCGTGAGCGCAAGGCCCTGATGGACGCGATCGCCAAGGACGAGGAAGCG
CGCTGGAACCTGCCCACGTGGTGGCTTGAGCAACTCCGCGCCGCATACCCGGATCGATGGATGGCATTGGCAGAGAGCGT
CAATGTCCGCCCGCCAATGACATTGCGCGTCAACACCAAGCGCCTGTCGGTCGACGAATACCTGAAGGAACTGGCCAACG
CGGGCATGGCGGGCACCGCCATCGGCCCTCAGGCCGTGCGGCTGGTTCGGGCATTTCCGGTATCGCAAGTGCCAGGTTTC
GCCACCGGCGATGTCTCCGTACAGGATGCCGGCGCCCAGCTTGCCGCGCCGCTCTGCGAGGTTGCCGACGGGATGCGCGT
GCTGGACGCCTGCGCGGCCCCCGGAGGCAAGACCGGCCATCTGCTCGAACTGGCCGATATCCATGTGACCGCCGTGGAGA
GCGATGCGGAGCGAGCCGCGCGCATTCATGAGAATCTGGCCCGCCTGGACCAGCGTGCCGAGGTCATCGTTGGCGATGCC
AGCCGCCCGAAGGACTGGTGGGATGGCCAGCAGTTCGACCGCATTCTGGCCGATGTGCCGTGCTCGGCGTCGGGCATCGT
CCGACGCCATCCCGATATCCGCTGGCTGCGACGCGAATCGGACATCGCGAAGCTTGTCAATGAGCAACGTCGCATCGTGT
CGCAATTGTGGTCGCTCCTTAAGCCAGGCGGCATTCTGGTCTATGTGACCTGTTCTATTTTCCCAACGGAGGGCGAGGAG
CAGGCGCTCTGGTTTGGTGCCCAGCTCCCAGATGCGATACGATTGCAGGCGCCCGGGCAGCTCCTGCCCGGCACGAAGGC
GCAGGAGACGGCCGGCACCAACATGGCCGGCCAGCCAAGCCTGCCATCGGATCACGATGGCTTCTACTACGCCCGCTTCC
AGAAACGCGCCTGA

Upstream 100 bases:

>100_bases
ACTGCCCGCTGTGTTCCGTCAGGAGCCGGCGGGCTTTTTCGTATCCGCACGCGCCCGACGGCCCGTACCACCCGTTTTTT
GCAGATTTCCGGTATTTCCC

Downstream 100 bases:

>100_bases
ATTCCACCGATGCTGAGCACGCCGCGCCTGTTCGACCTACGTGTCCCCGGTCACGCGTTGCGCGAGTGCCCGGCAGACTC
GCTGGTGAACACACTCCGCG

Product: tRNA and rRNA cytosine-C5-methylase

Products: NA

Alternate protein names: 16S rRNA m5C967 methyltransferase; rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MRLPPDSLAFQMLGAAAAVRGVHEGTALPQAIEDATNLLRLDRVRDAATRGAIQDLAYRTVRQFGATRALVTQLVTRPPG
ALVDSLLAVALALLLEGEEGDRSKVGRGGYSDFTVVDQAVSAAASEPKTAHARGLVNAVLRRFLRERKALMDAIAKDEEA
RWNLPTWWLEQLRAAYPDRWMALAESVNVRPPMTLRVNTKRLSVDEYLKELANAGMAGTAIGPQAVRLVRAFPVSQVPGF
ATGDVSVQDAGAQLAAPLCEVADGMRVLDACAAPGGKTGHLLELADIHVTAVESDAERAARIHENLARLDQRAEVIVGDA
SRPKDWWDGQQFDRILADVPCSASGIVRRHPDIRWLRRESDIAKLVNEQRRIVSQLWSLLKPGGILVYVTCSIFPTEGEE
QALWFGAQLPDAIRLQAPGQLLPGTKAQETAGTNMAGQPSLPSDHDGFYYARFQKRA

Sequences:

>Translated_457_residues
MRLPPDSLAFQMLGAAAAVRGVHEGTALPQAIEDATNLLRLDRVRDAATRGAIQDLAYRTVRQFGATRALVTQLVTRPPG
ALVDSLLAVALALLLEGEEGDRSKVGRGGYSDFTVVDQAVSAAASEPKTAHARGLVNAVLRRFLRERKALMDAIAKDEEA
RWNLPTWWLEQLRAAYPDRWMALAESVNVRPPMTLRVNTKRLSVDEYLKELANAGMAGTAIGPQAVRLVRAFPVSQVPGF
ATGDVSVQDAGAQLAAPLCEVADGMRVLDACAAPGGKTGHLLELADIHVTAVESDAERAARIHENLARLDQRAEVIVGDA
SRPKDWWDGQQFDRILADVPCSASGIVRRHPDIRWLRRESDIAKLVNEQRRIVSQLWSLLKPGGILVYVTCSIFPTEGEE
QALWFGAQLPDAIRLQAPGQLLPGTKAQETAGTNMAGQPSLPSDHDGFYYARFQKRA
>Mature_457_residues
MRLPPDSLAFQMLGAAAAVRGVHEGTALPQAIEDATNLLRLDRVRDAATRGAIQDLAYRTVRQFGATRALVTQLVTRPPG
ALVDSLLAVALALLLEGEEGDRSKVGRGGYSDFTVVDQAVSAAASEPKTAHARGLVNAVLRRFLRERKALMDAIAKDEEA
RWNLPTWWLEQLRAAYPDRWMALAESVNVRPPMTLRVNTKRLSVDEYLKELANAGMAGTAIGPQAVRLVRAFPVSQVPGF
ATGDVSVQDAGAQLAAPLCEVADGMRVLDACAAPGGKTGHLLELADIHVTAVESDAERAARIHENLARLDQRAEVIVGDA
SRPKDWWDGQQFDRILADVPCSASGIVRRHPDIRWLRRESDIAKLVNEQRRIVSQLWSLLKPGGILVYVTCSIFPTEGEE
QALWFGAQLPDAIRLQAPGQLLPGTKAQETAGTNMAGQPSLPSDHDGFYYARFQKRA

Specific function: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=273, Percent_Identity=27.4725274725275, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI76150623, Length=273, Percent_Identity=27.4725274725275, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI301336155, Length=280, Percent_Identity=29.2857142857143, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI32698918, Length=184, Percent_Identity=30.9782608695652, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI39995082, Length=308, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI2367212, Length=415, Percent_Identity=38.3132530120482, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI87081985, Length=308, Percent_Identity=29.5454545454545, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17536757, Length=270, Percent_Identity=28.1481481481481, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25143471, Length=229, Percent_Identity=33.1877729257642, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324268, Length=335, Percent_Identity=25.6716417910448, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319447, Length=302, Percent_Identity=28.476821192053, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI22024126, Length=282, Percent_Identity=27.6595744680851, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24668781, Length=249, Percent_Identity=34.136546184739, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21356513, Length=250, Percent_Identity=34, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21355201, Length=224, Percent_Identity=30.3571428571429, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19920494, Length=164, Percent_Identity=30.4878048780488, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: =2.1.1.176 [H]

Molecular weight: Translated: 49733; Mature: 49733

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLPPDSLAFQMLGAAAAVRGVHEGTALPQAIEDATNLLRLDRVRDAATRGAIQDLAYRT
CCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRQFGATRALVTQLVTRPPGALVDSLLAVALALLLEGEEGDRSKVGRGGYSDFTVVDQAV
HHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHH
SAAASEPKTAHARGLVNAVLRRFLRERKALMDAIAKDEEARWNLPTWWLEQLRAAYPDRW
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHH
MALAESVNVRPPMTLRVNTKRLSVDEYLKELANAGMAGTAIGPQAVRLVRAFPVSQVPGF
HHHHHHCCCCCCEEEEECCHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHCCCC
ATGDVSVQDAGAQLAAPLCEVADGMRVLDACAAPGGKTGHLLELADIHVTAVESDAERAA
CCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECEEEEEECCHHHHHH
RIHENLARLDQRAEVIVGDASRPKDWWDGQQFDRILADVPCSASGIVRRHPDIRWLRRES
HHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHHH
DIAKLVNEQRRIVSQLWSLLKPGGILVYVTCSIFPTEGEEQALWFGAQLPDAIRLQAPGQ
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCEEEECCCCCCCEEECCCCC
LLPGTKAQETAGTNMAGQPSLPSDHDGFYYARFQKRA
CCCCCCCHHHCCCCCCCCCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MRLPPDSLAFQMLGAAAAVRGVHEGTALPQAIEDATNLLRLDRVRDAATRGAIQDLAYRT
CCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRQFGATRALVTQLVTRPPGALVDSLLAVALALLLEGEEGDRSKVGRGGYSDFTVVDQAV
HHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHH
SAAASEPKTAHARGLVNAVLRRFLRERKALMDAIAKDEEARWNLPTWWLEQLRAAYPDRW
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHH
MALAESVNVRPPMTLRVNTKRLSVDEYLKELANAGMAGTAIGPQAVRLVRAFPVSQVPGF
HHHHHHCCCCCCEEEEECCHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHCCCC
ATGDVSVQDAGAQLAAPLCEVADGMRVLDACAAPGGKTGHLLELADIHVTAVESDAERAA
CCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECEEEEEECCHHHHHH
RIHENLARLDQRAEVIVGDASRPKDWWDGQQFDRILADVPCSASGIVRRHPDIRWLRRES
HHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHHH
DIAKLVNEQRRIVSQLWSLLKPGGILVYVTCSIFPTEGEEQALWFGAQLPDAIRLQAPGQ
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCEEEECCCCCCCEEECCCCC
LLPGTKAQETAGTNMAGQPSLPSDHDGFYYARFQKRA
CCCCCCCHHHCCCCCCCCCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA