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The map label for this gene is dapE [H]

Identifier: 94312373

GI number: 94312373

Start: 3716055

End: 3717323

Strand: Reverse

Name: dapE [H]

Synonym: Rmet_3442

Alternate gene names: 94312373

Gene position: 3717323-3716055 (Counterclockwise)

Preceding gene: 94312374

Following gene: 94312371

Centisome position: 94.63

GC content: 65.09

Gene sequence:

>1269_bases
ATGACCGCACGAGACAACATGAATCCCGTTGAAACCACGCTGACGCAATATATCGACCAACACCGCCCGCAACAGGAAGC
GTTCCTGGCCGAGCTGGTCAAGGTGCCGTCGGACAACCCCCCCGGCGATTGCGACGCCCATGGCAAGCGCGCCAAGGAAC
TGCTCGAAGGGCTGGGATTCAAGGTCGAGGCCCACAAGGTGCCCGAAGACAAGGTCCGTGCAGCCGGCATGATCAGCGCG
ACCAACCTGCTGGTGCGCAAGACGTTCGGCAACGGTGGACCGACCATCGCGATGAACGCCCACGGTGACGTGGTGCCTCC
GGGCCTGGGCTGGACCAAGGACCCGTACGGCGGCGAGATCGCTGACAGCGAACATGGCCCGGTGATGTTCGGCCGTGGCG
TGGCCGTGTCGAAGTCGGACTTCGCCACCTACGCCTACGCCGTGCTGGCGCTTCAGGAAGCCGAGAAGCAGGGCGCGAAG
CTGAACGGCACCGTCGAACTGCAGTTCACCTATGACGAGGAAACCGGTGGCGACATCGGTCCGAAGTTCCTGCTCGACGA
AGGCCTGACCAAGCCCGATTACGCAATCTCGGCCGGCTTCTCGTACGGCATCACGTCGGCCCACAACGGCTGTCTGCACG
TGGAAGTCACCGTCAAGGGCAAGCAGGGCCACGCCGCCATGCCGCACACTGGCGTGGACGCGATCGAGGCCGCCACGCAC
ATCCTGCAGGCGATCTACGGCCTGCGGGCCGAACTGGCCACGCGCAAGAGCAAGGTGCTCGGCATCGACACTGCCACGCT
GAACGTCGGCCTGATCAAGGGTGGCATCAACACCAACGTGGTGCCTGACCTGGTCACGTTCCGCGTGGACCGCCGCATGA
TTCCGGAAGAGATCGGTTTCGACGCCGAAGGCGAGCTCCGCGCTGTCGTGGAGAAGGCCGCCAAGGAGCGTCCGGGCATC
GAGGTGAAGGTAGAGCGCATCATCCTGGCCGAACCGCTGTCGGAACTGCCGGGCGTGGAGAAGCTGATCGGTGCCCTGAA
GCAACGCGCCGAGTCGGTCTTCGGCGTGGAGATTCCGGTGCAGGGCGTGCCGCTCTACACCGACGCTCGCCACTACACGA
GCCGTGGCATCCCGACCGTGCTGTACGGCGCCGGCCCGCGCACGCTGATGGAAGCCCGCGGCCACAACTCGGACGAGAAC
CTGCGTCTGAACGACCTGAACCGTGCCACCAAGGTCGTCGCGCTGGCACTGTCGGACCTGATGGCCTGA

Upstream 100 bases:

>100_bases
AGACGGCCGCGCGTGTGTTCGCCGATTTCGTCGAGCACTTCCATCGCCCCCAATAAGCGCCGCCATCGGCGTCGCCCCGA
AAACTCCAGAGATAACGAAG

Downstream 100 bases:

>100_bases
ACAAGACGCGCCCCCGCGAACTGTAGTACCCCTTGGTTGTGATGATGGCCCGCGAGACACTCGTCCGCGGGCCTTTTTTC
ATTCGGCGGCGTCTTCGTCC

Product: acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase-like protein

Products: NA

Alternate protein names: SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase [H]

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MTARDNMNPVETTLTQYIDQHRPQQEAFLAELVKVPSDNPPGDCDAHGKRAKELLEGLGFKVEAHKVPEDKVRAAGMISA
TNLLVRKTFGNGGPTIAMNAHGDVVPPGLGWTKDPYGGEIADSEHGPVMFGRGVAVSKSDFATYAYAVLALQEAEKQGAK
LNGTVELQFTYDEETGGDIGPKFLLDEGLTKPDYAISAGFSYGITSAHNGCLHVEVTVKGKQGHAAMPHTGVDAIEAATH
ILQAIYGLRAELATRKSKVLGIDTATLNVGLIKGGINTNVVPDLVTFRVDRRMIPEEIGFDAEGELRAVVEKAAKERPGI
EVKVERIILAEPLSELPGVEKLIGALKQRAESVFGVEIPVQGVPLYTDARHYTSRGIPTVLYGAGPRTLMEARGHNSDEN
LRLNDLNRATKVVALALSDLMA

Sequences:

>Translated_422_residues
MTARDNMNPVETTLTQYIDQHRPQQEAFLAELVKVPSDNPPGDCDAHGKRAKELLEGLGFKVEAHKVPEDKVRAAGMISA
TNLLVRKTFGNGGPTIAMNAHGDVVPPGLGWTKDPYGGEIADSEHGPVMFGRGVAVSKSDFATYAYAVLALQEAEKQGAK
LNGTVELQFTYDEETGGDIGPKFLLDEGLTKPDYAISAGFSYGITSAHNGCLHVEVTVKGKQGHAAMPHTGVDAIEAATH
ILQAIYGLRAELATRKSKVLGIDTATLNVGLIKGGINTNVVPDLVTFRVDRRMIPEEIGFDAEGELRAVVEKAAKERPGI
EVKVERIILAEPLSELPGVEKLIGALKQRAESVFGVEIPVQGVPLYTDARHYTSRGIPTVLYGAGPRTLMEARGHNSDEN
LRLNDLNRATKVVALALSDLMA
>Mature_421_residues
TARDNMNPVETTLTQYIDQHRPQQEAFLAELVKVPSDNPPGDCDAHGKRAKELLEGLGFKVEAHKVPEDKVRAAGMISAT
NLLVRKTFGNGGPTIAMNAHGDVVPPGLGWTKDPYGGEIADSEHGPVMFGRGVAVSKSDFATYAYAVLALQEAEKQGAKL
NGTVELQFTYDEETGGDIGPKFLLDEGLTKPDYAISAGFSYGITSAHNGCLHVEVTVKGKQGHAAMPHTGVDAIEAATHI
LQAIYGLRAELATRKSKVLGIDTATLNVGLIKGGINTNVVPDLVTFRVDRRMIPEEIGFDAEGELRAVVEKAAKERPGIE
VKVERIILAEPLSELPGVEKLIGALKQRAESVFGVEIPVQGVPLYTDARHYTSRGIPTVLYGAGPRTLMEARGHNSDENL
RLNDLNRATKVVALALSDLMA

Specific function: Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bact

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=352, Percent_Identity=26.4204545454545, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17538642, Length=323, Percent_Identity=27.2445820433437, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21356353, Length=419, Percent_Identity=26.491646778043, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24649202, Length=335, Percent_Identity=28.6567164179104, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649204, Length=335, Percent_Identity=28.6567164179104, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649206, Length=395, Percent_Identity=24.0506329113924, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24649210, Length=342, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR005941
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 45286; Mature: 45155

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARDNMNPVETTLTQYIDQHRPQQEAFLAELVKVPSDNPPGDCDAHGKRAKELLEGLGF
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCC
KVEAHKVPEDKVRAAGMISATNLLVRKTFGNGGPTIAMNAHGDVVPPGLGWTKDPYGGEI
EEEECCCCHHHHHHHCCHHHHHEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCC
ADSEHGPVMFGRGVAVSKSDFATYAYAVLALQEAEKQGAKLNGTVELQFTYDEETGGDIG
CCCCCCCEEEECCEEECCCHHHHHHHHHHHHHHHHHCCCEECCEEEEEEEECCCCCCCCC
PKFLLDEGLTKPDYAISAGFSYGITSAHNGCLHVEVTVKGKQGHAAMPHTGVDAIEAATH
CHHHHHCCCCCCCCEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHH
ILQAIYGLRAELATRKSKVLGIDTATLNVGLIKGGINTNVVPDLVTFRVDRRMIPEEIGF
HHHHHHHHHHHHHHHHHHEEEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCHHHHCC
DAEGELRAVVEKAAKERPGIEVKVERIILAEPLSELPGVEKLIGALKQRAESVFGVEIPV
CCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHCCCHHHHHHHHHHHHHHHEEEECCC
QGVPLYTDARHYTSRGIPTVLYGAGPRTLMEARGHNSDENLRLNDLNRATKVVALALSDL
CCCCEEECCHHHHCCCCCEEEECCCCHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHH
MA
CC
>Mature Secondary Structure 
TARDNMNPVETTLTQYIDQHRPQQEAFLAELVKVPSDNPPGDCDAHGKRAKELLEGLGF
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCC
KVEAHKVPEDKVRAAGMISATNLLVRKTFGNGGPTIAMNAHGDVVPPGLGWTKDPYGGEI
EEEECCCCHHHHHHHCCHHHHHEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCC
ADSEHGPVMFGRGVAVSKSDFATYAYAVLALQEAEKQGAKLNGTVELQFTYDEETGGDIG
CCCCCCCEEEECCEEECCCHHHHHHHHHHHHHHHHHCCCEECCEEEEEEEECCCCCCCCC
PKFLLDEGLTKPDYAISAGFSYGITSAHNGCLHVEVTVKGKQGHAAMPHTGVDAIEAATH
CHHHHHCCCCCCCCEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHH
ILQAIYGLRAELATRKSKVLGIDTATLNVGLIKGGINTNVVPDLVTFRVDRRMIPEEIGF
HHHHHHHHHHHHHHHHHHEEEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCHHHHCC
DAEGELRAVVEKAAKERPGIEVKVERIILAEPLSELPGVEKLIGALKQRAESVFGVEIPV
CCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHCCCHHHHHHHHHHHHHHHEEEECCC
QGVPLYTDARHYTSRGIPTVLYGAGPRTLMEARGHNSDENLRLNDLNRATKVVALALSDL
CCCCEEECCHHHHCCCCCEEEECCCCHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHH
MA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA