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The map label for this gene is eamA [H]

Identifier: 94312356

GI number: 94312356

Start: 3703970

End: 3704863

Strand: Reverse

Name: eamA [H]

Synonym: Rmet_3425

Alternate gene names: 94312356

Gene position: 3704863-3703970 (Counterclockwise)

Preceding gene: 94312357

Following gene: 94312355

Centisome position: 94.32

GC content: 67.67

Gene sequence:

>894_bases
ATGCAAGCCAAAGACCGTCTGCTTGCCCTGGCCATCATCGTGGTCTGGGGCGTCAATTTCGTCGTCATCAAGGTCGGCCT
CGTCGGCGTGCCGCCAATGCTGCTGGGCGCGCTGCGCTTCTGCCTGGTGGCGTTTCCGGCTGTTTTCTTTATCCCTCGGC
CACGCATTCCGCTGCGGATGCTGGTGGCCTACGGCGCCACCATCAGCCTTGGGCAGTTCGTGTTCCTGTTCTACGCGATG
GCCGTCGGGATGCCGGCGGGGCTGGCATCGCTGGTGCTGCAGTCGCAGGTGTTCTTCACCGTGGCCATCGCCGGGTTCTG
GCTTGGCGAGCCGGTGCGCTGGCACAACATCGCTGGCATGGCCATCGCCGCCTGCGGGCTCGCCCTGATCGGCAGCGGCG
CCGCTCACGGCCCGGGCGGCATGACGCTGGCCGGCTTCCTGCTGACGCTGTGCGCCGCCCTGTGCTGGGCCACGGGCAAC
ATCGTCAGCAAGAAGATTGGGCCGGTGGATCTGCTGGGCCTGGTGGTGTGGGGCGCGCTGATCCCGATCGTGCCGTTCGC
GCTGCTGTCGCTCTGGTTCGAGGGCCCGGCCCGGATGACGCAGGCGCTGACCAATATCTCCGGCATGGGTGTGTTCGCGG
TCTGCTACCTGGCGTTCTGCGCCACGCTGTTCGGCTACACGATGTGGGGCCGCCTGCTGACGCGCTACGCGGCCAGCAAG
GTGGCGCCGCTGACGCTGCTGGTGCCGGTGGTCGGCCTGGTCTCCGCACACCTGCTGCTGGGCGAAGCATTGGCGCTGAC
ACAATGGGCTGGCGCCCTGGTGGTAATGGCCGGACTGCTACTCAACGTGTTCGGCGGGCGGCTGTGGGCCGGTCGGATGC
TCGCTGGGCGATGA

Upstream 100 bases:

>100_bases
CGCAAAACCGCAGGATCGTGCAACGCCGCGCCGCCACGGGCTGATACGCTAGCCGTGCCGGTCATCCCGCCCCCAGGGAT
GCGGCGATCCCTCTTCGATC

Downstream 100 bases:

>100_bases
TTTCGAGGGTTAACCCGTATATTTAGCCGCCGTTCCCGCATTTTTGCGCATATGGATATCACGTGCGAATCCGTATCGTT
GCCGCATCTTGAGGCAAAAT

Product: cysteine and O-acetyl-L-serine efflux system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MQAKDRLLALAIIVVWGVNFVVIKVGLVGVPPMLLGALRFCLVAFPAVFFIPRPRIPLRMLVAYGATISLGQFVFLFYAM
AVGMPAGLASLVLQSQVFFTVAIAGFWLGEPVRWHNIAGMAIAACGLALIGSGAAHGPGGMTLAGFLLTLCAALCWATGN
IVSKKIGPVDLLGLVVWGALIPIVPFALLSLWFEGPARMTQALTNISGMGVFAVCYLAFCATLFGYTMWGRLLTRYAASK
VAPLTLLVPVVGLVSAHLLLGEALALTQWAGALVVMAGLLLNVFGGRLWAGRMLAGR

Sequences:

>Translated_297_residues
MQAKDRLLALAIIVVWGVNFVVIKVGLVGVPPMLLGALRFCLVAFPAVFFIPRPRIPLRMLVAYGATISLGQFVFLFYAM
AVGMPAGLASLVLQSQVFFTVAIAGFWLGEPVRWHNIAGMAIAACGLALIGSGAAHGPGGMTLAGFLLTLCAALCWATGN
IVSKKIGPVDLLGLVVWGALIPIVPFALLSLWFEGPARMTQALTNISGMGVFAVCYLAFCATLFGYTMWGRLLTRYAASK
VAPLTLLVPVVGLVSAHLLLGEALALTQWAGALVVMAGLLLNVFGGRLWAGRMLAGR
>Mature_297_residues
MQAKDRLLALAIIVVWGVNFVVIKVGLVGVPPMLLGALRFCLVAFPAVFFIPRPRIPLRMLVAYGATISLGQFVFLFYAM
AVGMPAGLASLVLQSQVFFTVAIAGFWLGEPVRWHNIAGMAIAACGLALIGSGAAHGPGGMTLAGFLLTLCAALCWATGN
IVSKKIGPVDLLGLVVWGALIPIVPFALLSLWFEGPARMTQALTNISGMGVFAVCYLAFCATLFGYTMWGRLLTRYAASK
VAPLTLLVPVVGLVSAHLLLGEALALTQWAGALVVMAGLLLNVFGGRLWAGRMLAGR

Specific function: May be an export pump for cysteine and other metabolites of the cysteine pathway (such as N-acetyl-L-serine (NAS) and O- acetyl-L-serine (OAS)), and for other amino acids and their metabolites [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains [H]

Homologues:

Organism=Escherichia coli, GI87081929, Length=291, Percent_Identity=51.5463917525773, Blast_Score=262, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000620 [H]

Pfam domain/function: PF00892 DUF6 [H]

EC number: NA

Molecular weight: Translated: 31271; Mature: 31271

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAKDRLLALAIIVVWGVNFVVIKVGLVGVPPMLLGALRFCLVAFPAVFFIPRPRIPLRM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LVAYGATISLGQFVFLFYAMAVGMPAGLASLVLQSQVFFTVAIAGFWLGEPVRWHNIAGM
HHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AIAACGLALIGSGAAHGPGGMTLAGFLLTLCAALCWATGNIVSKKIGPVDLLGLVVWGAL
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHH
IPIVPFALLSLWFEGPARMTQALTNISGMGVFAVCYLAFCATLFGYTMWGRLLTRYAASK
HHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAPLTLLVPVVGLVSAHLLLGEALALTQWAGALVVMAGLLLNVFGGRLWAGRMLAGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHCCC
>Mature Secondary Structure
MQAKDRLLALAIIVVWGVNFVVIKVGLVGVPPMLLGALRFCLVAFPAVFFIPRPRIPLRM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LVAYGATISLGQFVFLFYAMAVGMPAGLASLVLQSQVFFTVAIAGFWLGEPVRWHNIAGM
HHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AIAACGLALIGSGAAHGPGGMTLAGFLLTLCAALCWATGNIVSKKIGPVDLLGLVVWGAL
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHH
IPIVPFALLSLWFEGPARMTQALTNISGMGVFAVCYLAFCATLFGYTMWGRLLTRYAASK
HHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAPLTLLVPVVGLVSAHLLLGEALALTQWAGALVVMAGLLLNVFGGRLWAGRMLAGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8383113; 9097039; 9278503; 10844694 [H]