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The map label for this gene is mtgA

Identifier: 94311984

GI number: 94311984

Start: 3310025

End: 3310726

Strand: Reverse

Name: mtgA

Synonym: Rmet_3053

Alternate gene names: 94311984

Gene position: 3310726-3310025 (Counterclockwise)

Preceding gene: 94311985

Following gene: 94311981

Centisome position: 84.28

GC content: 62.82

Gene sequence:

>702_bases
TTGCGCTGGCTGGCCTATCTGGCCGGCTGCCTGATCGTTGGCGTGGTGGCGATGCAGGTCTATTTCTTCCTGCAGATCGC
TGCCTGGCAGGTCGTCAATCCGTCGTCCACCACGTTCATGCGTGCCGAGCGCTGGCGGCTGTGCGGCTTCAATTTCTGGA
GCTGCCCGGTGCAGCGGCAATGGGTGCGCTACGACGAAATCTCGCGCAACATCAAGCGCGCCGTGATCGCCAGCGAGGAT
GCCGACTTCGTCAATCATCCCGGCTACGAACTTGATGCGATGCTCGATGCCTGGGAACGCAACAAGCAGCGTGGACGCAT
CGTGCGCGGCGGTTCCACCATCACGCAGCAACTGGCCAAGAACCTGTTCCTGTCTTCGGAGCAGAACTACCTGCGCAAGG
GCCAGGAACTGGCGATCACGTGGATGCTGGAGCTCTGGCTCGACAAGCAGCGGATCTTCGAGATTTACCTGAATTCGGTG
GAGTGGGGCGAAGGCGTGTTCGGCGTCGAGGCTGCCGCGCAGCACTACTTCCATACCTCGGCTTCGAAGCTCAGCGTGGG
GCAGGCCGCCCGGCTCGCGGCCGCGCTACCGGCGCCCAAGTGCTTCGACAAGAAGCAGTACTGCGCCAACGTGCACGTGA
ACTTCCGCGTCAAGGCGTCGATCATCGCCAGGCGGATGGGCGCGGCAACGTTGCCGGACTAG

Upstream 100 bases:

>100_bases
CCGAAGCCGCCCGCTAAGGCGGCGTTGACGCAGCGTGGCCCGCGCATCCGCCAGATCGTCACCACGATCGTCGGCAAGTA
GCGCCGGCGGGGCGAACCCG

Downstream 100 bases:

>100_bases
GGGCGGTTCCCCCCTCTCATGCTTGTGGGAGAGGGGACCAGGAAGGCTATCAGCTCAGCCAGCCCTTCCTGCGGAAATAC
ACCAGCGGAATCGCCGCGGA

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MRWLAYLAGCLIVGVVAMQVYFFLQIAAWQVVNPSSTTFMRAERWRLCGFNFWSCPVQRQWVRYDEISRNIKRAVIASED
ADFVNHPGYELDAMLDAWERNKQRGRIVRGGSTITQQLAKNLFLSSEQNYLRKGQELAITWMLELWLDKQRIFEIYLNSV
EWGEGVFGVEAAAQHYFHTSASKLSVGQAARLAAALPAPKCFDKKQYCANVHVNFRVKASIIARRMGAATLPD

Sequences:

>Translated_233_residues
MRWLAYLAGCLIVGVVAMQVYFFLQIAAWQVVNPSSTTFMRAERWRLCGFNFWSCPVQRQWVRYDEISRNIKRAVIASED
ADFVNHPGYELDAMLDAWERNKQRGRIVRGGSTITQQLAKNLFLSSEQNYLRKGQELAITWMLELWLDKQRIFEIYLNSV
EWGEGVFGVEAAAQHYFHTSASKLSVGQAARLAAALPAPKCFDKKQYCANVHVNFRVKASIIARRMGAATLPD
>Mature_233_residues
MRWLAYLAGCLIVGVVAMQVYFFLQIAAWQVVNPSSTTFMRAERWRLCGFNFWSCPVQRQWVRYDEISRNIKRAVIASED
ADFVNHPGYELDAMLDAWERNKQRGRIVRGGSTITQQLAKNLFLSSEQNYLRKGQELAITWMLELWLDKQRIFEIYLNSV
EWGEGVFGVEAAAQHYFHTSASKLSVGQAARLAAALPAPKCFDKKQYCANVHVNFRVKASIIARRMGAATLPD

Specific function: Cell wall formation

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family

Homologues:

Organism=Escherichia coli, GI1789601, Length=142, Percent_Identity=48.5915492957746, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI87082258, Length=146, Percent_Identity=36.986301369863, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1786343, Length=134, Percent_Identity=35.8208955223881, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788867, Length=204, Percent_Identity=29.9019607843137, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTGA_RALME (Q1LIV1)

Other databases:

- EMBL:   CP000352
- RefSeq:   YP_585194.1
- ProteinModelPortal:   Q1LIV1
- SMR:   Q1LIV1
- STRING:   Q1LIV1
- GeneID:   4039881
- GenomeReviews:   CP000352_GR
- KEGG:   rme:Rmet_3053
- eggNOG:   COG0744
- HOGENOM:   HBG685698
- OMA:   RISIHLK
- PhylomeDB:   Q1LIV1
- ProtClustDB:   PRK00056
- BioCyc:   RMET266264:RMET_3053-MONOMER
- HAMAP:   MF_00766
- InterPro:   IPR001264
- InterPro:   IPR011812
- TIGRFAMs:   TIGR02070

Pfam domain/function: PF00912 Transgly

EC number: 2.4.2.- [C]

Molecular weight: Translated: 26675; Mature: 26675

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1907c848)-;

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWLAYLAGCLIVGVVAMQVYFFLQIAAWQVVNPSSTTFMRAERWRLCGFNFWSCPVQRQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCCCCCCCCHHHH
WVRYDEISRNIKRAVIASEDADFVNHPGYELDAMLDAWERNKQRGRIVRGGSTITQQLAK
HHHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHHHHHHHCCHHCCCEEECCHHHHHHHHH
NLFLSSEQNYLRKGQELAITWMLELWLDKQRIFEIYLNSVEWGEGVFGVEAAAQHYFHTS
HHHCCCCHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
ASKLSVGQAARLAAALPAPKCFDKKQYCANVHVNFRVKASIIARRMGAATLPD
CHHHHHHHHHHHHHHCCCCHHCCCHHHHEECEEEEEEHHHHHHHHHCCCCCCH
>Mature Secondary Structure
MRWLAYLAGCLIVGVVAMQVYFFLQIAAWQVVNPSSTTFMRAERWRLCGFNFWSCPVQRQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCCCCCCCCHHHH
WVRYDEISRNIKRAVIASEDADFVNHPGYELDAMLDAWERNKQRGRIVRGGSTITQQLAK
HHHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHHHHHHHCCHHCCCEEECCHHHHHHHHH
NLFLSSEQNYLRKGQELAITWMLELWLDKQRIFEIYLNSVEWGEGVFGVEAAAQHYFHTS
HHHCCCCHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
ASKLSVGQAARLAAALPAPKCFDKKQYCANVHVNFRVKASIIARRMGAATLPD
CHHHHHHHHHHHHHHCCCCHHCCCHHHHEECEEEEEEHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA