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The map label for this gene is aroE [H]

Identifier: 94311985

GI number: 94311985

Start: 3310810

End: 3311718

Strand: Reverse

Name: aroE [H]

Synonym: Rmet_3054

Alternate gene names: 94311985

Gene position: 3311718-3310810 (Counterclockwise)

Preceding gene: 94311986

Following gene: 94311984

Centisome position: 84.31

GC content: 67.33

Gene sequence:

>909_bases
ATGACCGCAGACCAGAATTCCCAGCCCAACACCGCCGAACCTGCCGATAGCGTCGACCGCTACGTGGTGGTGGGCAATCC
GATTTCGCACAGCCGCTCGCCGGCGATCCATGCCGCCTTCGCGCGCCAGACCGGCGAGGCGGTGCAGTATGACCGGCTCG
AAGCCCCGCTCGATGCGTTCGCAGATACGATGCGCGAATTCCTGGCCGGCGGAGGCCATGGCTTCAACGTAACCGTGCCG
TTCAAGCTCGAAGCGTATGACCTGGCCGATCGCCTCACGCCGCGTGCCGAGGCTGCCGGCGCCGTCAACACGATGTGGAT
CGAGGACGGACTGATCCATGGCGACAACACCGACGGCATCGGCCTGGTGCGTGACATTCAGGACAACCTTGATGTGCTGC
TCGAAGACAAGCGCATTCTGGTGCTTGGCGCCGGTGGCGCCGCGATGGGCGCGATGCTGCCGCTGATCGAATGCCGCCCG
GCGCGCATCGTGGTGGCCAACCGTACCGCCTCGCGCGCCAGCGACATGGTCGAGGAATTCGTGGAAGCGGCGGACCAGTA
CAACGTGGAGCTGTGGGCCGGTGGCCTCGACGCGCTCGATGCGCTGTCCGAGGACGAGCGCTGCGATGTGGTGATCAATG
CGTCGTCCAGCAGCCTGCAAGGCGAAGTGCCGCCCGTGCCCGAGCACCTGCTCGGCGAAGGCGTGCTGGCGTACGACATG
ATGTACGGCGCGCAGCCGACGGTGTTCCTGGCCTATGCGGCCAAATGCGGCGCGCGCACGGCGGATGGGCTTGGCATGCT
GGTCGAACAGGCTGCCGAAGCCTTCTACAACTGGCGCGGCGTGCGGCCCAGCACCGCCCCCGTGCTGGCCGAGCTGCGCG
CGGCGCTGCAGGCCGAAGCCGCCCGCTAA

Upstream 100 bases:

>100_bases
CGTTCACGGCGGAGATGCAGGCGAAGCAGGATATCCTCGAAGTCGTTTCCACTTTCAAGTTCACCCGCAGCGGGCTCGAT
GTCCGCCTGCAAGGCCGCTG

Downstream 100 bases:

>100_bases
GGCGGCGTTGACGCAGCGTGGCCCGCGCATCCGCCAGATCGTCACCACGATCGTCGGCAAGTAGCGCCGGCGGGGCGAAC
CCGTTGCGCTGGCTGGCCTA

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MTADQNSQPNTAEPADSVDRYVVVGNPISHSRSPAIHAAFARQTGEAVQYDRLEAPLDAFADTMREFLAGGGHGFNVTVP
FKLEAYDLADRLTPRAEAAGAVNTMWIEDGLIHGDNTDGIGLVRDIQDNLDVLLEDKRILVLGAGGAAMGAMLPLIECRP
ARIVVANRTASRASDMVEEFVEAADQYNVELWAGGLDALDALSEDERCDVVINASSSSLQGEVPPVPEHLLGEGVLAYDM
MYGAQPTVFLAYAAKCGARTADGLGMLVEQAAEAFYNWRGVRPSTAPVLAELRAALQAEAAR

Sequences:

>Translated_302_residues
MTADQNSQPNTAEPADSVDRYVVVGNPISHSRSPAIHAAFARQTGEAVQYDRLEAPLDAFADTMREFLAGGGHGFNVTVP
FKLEAYDLADRLTPRAEAAGAVNTMWIEDGLIHGDNTDGIGLVRDIQDNLDVLLEDKRILVLGAGGAAMGAMLPLIECRP
ARIVVANRTASRASDMVEEFVEAADQYNVELWAGGLDALDALSEDERCDVVINASSSSLQGEVPPVPEHLLGEGVLAYDM
MYGAQPTVFLAYAAKCGARTADGLGMLVEQAAEAFYNWRGVRPSTAPVLAELRAALQAEAAR
>Mature_301_residues
TADQNSQPNTAEPADSVDRYVVVGNPISHSRSPAIHAAFARQTGEAVQYDRLEAPLDAFADTMREFLAGGGHGFNVTVPF
KLEAYDLADRLTPRAEAAGAVNTMWIEDGLIHGDNTDGIGLVRDIQDNLDVLLEDKRILVLGAGGAAMGAMLPLIECRPA
RIVVANRTASRASDMVEEFVEAADQYNVELWAGGLDALDALSEDERCDVVINASSSSLQGEVPPVPEHLLGEGVLAYDMM
YGAQPTVFLAYAAKCGARTADGLGMLVEQAAEAFYNWRGVRPSTAPVLAELRAALQAEAAR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=287, Percent_Identity=44.5993031358885, Blast_Score=227, Evalue=7e-61,
Organism=Escherichia coli, GI1787983, Length=279, Percent_Identity=30.1075268817204, Blast_Score=99, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6320332, Length=275, Percent_Identity=27.6363636363636, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 32214; Mature: 32083

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADQNSQPNTAEPADSVDRYVVVGNPISHSRSPAIHAAFARQTGEAVQYDRLEAPLDAF
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCHHHH
ADTMREFLAGGGHGFNVTVPFKLEAYDLADRLTPRAEAAGAVNTMWIEDGLIHGDNTDGI
HHHHHHHHCCCCCCEEEEEEEEEEHHHHHHHCCCCHHHCCCEEEEEEECCEEECCCCCCC
GLVRDIQDNLDVLLEDKRILVLGAGGAAMGAMLPLIECRPARIVVANRTASRASDMVEEF
EEHHHHHHCCCEEEECCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHH
VEAADQYNVELWAGGLDALDALSEDERCDVVINASSSSLQGEVPPVPEHLLGEGVLAYDM
HHHHHHCCEEEEECCHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCHHHHCCCHHHHHH
MYGAQPTVFLAYAAKCGARTADGLGMLVEQAAEAFYNWRGVRPSTAPVLAELRAALQAEA
HHCCCCCEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
AR
CC
>Mature Secondary Structure 
TADQNSQPNTAEPADSVDRYVVVGNPISHSRSPAIHAAFARQTGEAVQYDRLEAPLDAF
CCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCHHHH
ADTMREFLAGGGHGFNVTVPFKLEAYDLADRLTPRAEAAGAVNTMWIEDGLIHGDNTDGI
HHHHHHHHCCCCCCEEEEEEEEEEHHHHHHHCCCCHHHCCCEEEEEEECCEEECCCCCCC
GLVRDIQDNLDVLLEDKRILVLGAGGAAMGAMLPLIECRPARIVVANRTASRASDMVEEF
EEHHHHHHCCCEEEECCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHH
VEAADQYNVELWAGGLDALDALSEDERCDVVINASSSSLQGEVPPVPEHLLGEGVLAYDM
HHHHHHCCEEEEECCHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCHHHHCCCHHHHHH
MYGAQPTVFLAYAAKCGARTADGLGMLVEQAAEAFYNWRGVRPSTAPVLAELRAALQAEA
HHCCCCCEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
AR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA