The gene/protein map for NC_007973 is currently unavailable.
Definition Cupriavidus metallidurans CH34 chromosome, complete genome.
Accession NC_007973
Length 3,928,089

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The map label for this gene is chnA [H]

Identifier: 94310277

GI number: 94310277

Start: 1446018

End: 1446806

Strand: Direct

Name: chnA [H]

Synonym: Rmet_1335

Alternate gene names: 94310277

Gene position: 1446018-1446806 (Clockwise)

Preceding gene: 94310276

Following gene: 94310278

Centisome position: 36.81

GC content: 64.64

Gene sequence:

>789_bases
ATGAATCAATCAAATCCCGAAGGAGGACGATTCACTATGAAATACATCTTCAAAGGTGACAGCGCGCTGGTCAGTGGCGC
CGGCTCGGGTATCGGCGAGGCAACGGCACACCTGCTCGCCATAAATGGTGTGCAGGTGGTTGCCTCCGACATCGACTTCG
AGGCCGCCCGACGTGTGACACAGGCCATCATCGCCGCCGGCGGCCGCGCCGTGGCACACGAGGGCAATGCGGCCAAACCC
GAGGACGCCGGTGCGGCGGTGCAGTGCGCACTCAAGCATTTCGGTTCTCTGCACCTGGCTTTCAACAACGCTGGCATTGC
CGGAGAACTCAAGCCTGCAGGCGAACTGGCGGCCGAGGAATGGCAACGTGTCATCGATACCAACCTCTCGGGTGTGCAGC
ATGCCATGCGCGCGCAGATCCCGGCCATCCTGGCCGCCGGCGGCGGCGCCATCGTCAACATGTCGTCGGTCCTGGGATTA
GTCGGCAGCGCGGACGCACCGGCCTACGTCGCGGCCAAGCACGGGGTGACAGGTCTCACGCGCTCGGCGGCGTTGGCCTA
TTCGGCACAGGGCGTCCGCATCAACTCGCTCCATCCGGGCTATATCGAAACTCCGCTGCTCAAGGCGCTCGACGAGGCCA
CACTGGCAGCGCTGAAGGGGCTGCACGCCATCGGGCGCCTGGGCCGGCCCGAGGAGATCGCCCACGCAGCCTGCTTCCTG
CTGTCCGAAGGTGCCAGCTTCATGTGCGGCAGCGCCATGGTGGTAGATGGCGGTTATACGGCGGCTTGA

Upstream 100 bases:

>100_bases
GCGCCGGTACGCACTGCGGCGGCGCATCTTTGCGACGCGCTCTGGCGTGCTGTGCCATCGCACTCGTGCTAGTTGAGCGC
GGAGAGTCACCGTCCGAACT

Downstream 100 bases:

>100_bases
ATAGGAAGGGCACAGTGGAGTTGCGCCACCTTCGATGCTTCATCGCTGTCGCGGAAGAACTCCACTTCGCGCGCGCCGCC
GAGCGGCTACATATCGAGCA

Product: cyclohexanol dehydrogenase

Products: NA

Alternate protein names: 2,5-DDOL dehydrogenase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MNQSNPEGGRFTMKYIFKGDSALVSGAGSGIGEATAHLLAINGVQVVASDIDFEAARRVTQAIIAAGGRAVAHEGNAAKP
EDAGAAVQCALKHFGSLHLAFNNAGIAGELKPAGELAAEEWQRVIDTNLSGVQHAMRAQIPAILAAGGGAIVNMSSVLGL
VGSADAPAYVAAKHGVTGLTRSAALAYSAQGVRINSLHPGYIETPLLKALDEATLAALKGLHAIGRLGRPEEIAHAACFL
LSEGASFMCGSAMVVDGGYTAA

Sequences:

>Translated_262_residues
MNQSNPEGGRFTMKYIFKGDSALVSGAGSGIGEATAHLLAINGVQVVASDIDFEAARRVTQAIIAAGGRAVAHEGNAAKP
EDAGAAVQCALKHFGSLHLAFNNAGIAGELKPAGELAAEEWQRVIDTNLSGVQHAMRAQIPAILAAGGGAIVNMSSVLGL
VGSADAPAYVAAKHGVTGLTRSAALAYSAQGVRINSLHPGYIETPLLKALDEATLAALKGLHAIGRLGRPEEIAHAACFL
LSEGASFMCGSAMVVDGGYTAA
>Mature_262_residues
MNQSNPEGGRFTMKYIFKGDSALVSGAGSGIGEATAHLLAINGVQVVASDIDFEAARRVTQAIIAAGGRAVAHEGNAAKP
EDAGAAVQCALKHFGSLHLAFNNAGIAGELKPAGELAAEEWQRVIDTNLSGVQHAMRAQIPAILAAGGGAIVNMSSVLGL
VGSADAPAYVAAKHGVTGLTRSAALAYSAQGVRINSLHPGYIETPLLKALDEATLAALKGLHAIGRLGRPEEIAHAACFL
LSEGASFMCGSAMVVDGGYTAA

Specific function: Catalyzes the degradation of 2,5-dichloro-2,5- cyclohexadiene-1,4-diol (2,5-DDOL) into 2,5-dichlorohydroquinone (2,5-DCHQ) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=246, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI32483357, Length=242, Percent_Identity=30.9917355371901, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=30, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI59889578, Length=223, Percent_Identity=32.7354260089686, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI40254992, Length=238, Percent_Identity=31.5126050420168, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=32.6771653543307, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=31.8407960199005, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI126723750, Length=245, Percent_Identity=28.9795918367347, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4758504, Length=258, Percent_Identity=29.8449612403101, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI66933014, Length=174, Percent_Identity=31.6091954022989, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI224922801, Length=179, Percent_Identity=30.7262569832402, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=27.9527559055118, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI7705925, Length=257, Percent_Identity=29.9610894941634, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI4504505, Length=236, Percent_Identity=30.0847457627119, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI4503301, Length=249, Percent_Identity=28.1124497991968, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI83715985, Length=253, Percent_Identity=29.2490118577075, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI126723191, Length=192, Percent_Identity=26.5625, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=31.2252964426877, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=32.6446280991736, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=31.7073170731707, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=29.6, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI2367175, Length=243, Percent_Identity=35.3909465020576, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=29.7959183673469, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=30.8641975308642, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=28.0632411067194, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=29.5275590551181, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=30.8, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=27.2357723577236, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1787820, Length=188, Percent_Identity=25.531914893617, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI1789057, Length=252, Percent_Identity=28.5714285714286, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1787526, Length=185, Percent_Identity=28.6486486486486, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=31.4741035856574, Blast_Score=116, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17555706, Length=260, Percent_Identity=33.0769230769231, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=32.6693227091633, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=32.258064516129, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=29.9180327868852, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=31.5589353612167, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=30.8880308880309, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=28.3464566929134, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=30.5019305019305, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=277, Percent_Identity=30.3249097472924, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=30.3370786516854, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562904, Length=259, Percent_Identity=30.1158301158301, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=31.1787072243346, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17544670, Length=261, Percent_Identity=26.4367816091954, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=29.5019157088123, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=267, Percent_Identity=28.8389513108614, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=29.368029739777, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=267, Percent_Identity=29.9625468164794, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=28.7313432835821, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=27.4809160305344, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=27.9850746268657, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=28.030303030303, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=28.6259541984733, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=252, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=190, Percent_Identity=26.8421052631579, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=261, Percent_Identity=28.3524904214559, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=197, Percent_Identity=26.9035532994924, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=196, Percent_Identity=30.6122448979592, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=248, Percent_Identity=28.2258064516129, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=29.6442687747036, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=27.3764258555133, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=253, Percent_Identity=29.6442687747036, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=193, Percent_Identity=23.3160621761658, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI115534660, Length=204, Percent_Identity=27.9411764705882, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=200, Percent_Identity=25, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=31.25, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323882, Length=189, Percent_Identity=27.5132275132275, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=274, Percent_Identity=27.3722627737226, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=33.3333333333333, Blast_Score=120, Evalue=7e-28,
Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=36, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=34.6456692913386, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=34.6613545816733, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=33.6, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24644337, Length=259, Percent_Identity=35.5212355212355, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17737361, Length=240, Percent_Identity=34.1666666666667, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=31.25, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=29.2, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI18859837, Length=195, Percent_Identity=30.7692307692308, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24640492, Length=194, Percent_Identity=26.2886597938144, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281364892, Length=202, Percent_Identity=30.1980198019802, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26506; Mature: 26506

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MNQSNPEGGRFTMKYIFKGDSALVSGAGSGIGEATAHLLAINGVQVVASDIDFEAARRVT
CCCCCCCCCEEEEEEEEECCCCEEECCCCCHHHHHHHEEEECCCEEEEECCCHHHHHHHH
QAIIAAGGRAVAHEGNAAKPEDAGAAVQCALKHFGSLHLAFNNAGIAGELKPAGELAAEE
HHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHH
WQRVIDTNLSGVQHAMRAQIPAILAAGGGAIVNMSSVLGLVGSADAPAYVAAKHGVTGLT
HHHHHHCCHHHHHHHHHHHCCEEEECCCCCEEEHHHHHHHHCCCCCCEEEEECCCCCHHH
RSAALAYSAQGVRINSLHPGYIETPLLKALDEATLAALKGLHAIGRLGRPEEIAHAACFL
HHHHHEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LSEGASFMCGSAMVVDGGYTAA
HHCCCCEEECCEEEECCCCCCC
>Mature Secondary Structure
MNQSNPEGGRFTMKYIFKGDSALVSGAGSGIGEATAHLLAINGVQVVASDIDFEAARRVT
CCCCCCCCCEEEEEEEEECCCCEEECCCCCHHHHHHHEEEECCCEEEEECCCHHHHHHHH
QAIIAAGGRAVAHEGNAAKPEDAGAAVQCALKHFGSLHLAFNNAGIAGELKPAGELAAEE
HHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHH
WQRVIDTNLSGVQHAMRAQIPAILAAGGGAIVNMSSVLGLVGSADAPAYVAAKHGVTGLT
HHHHHHCCHHHHHHHHHHHCCEEEECCCCCEEEHHHHHHHHCCCCCCEEEEECCCCCHHH
RSAALAYSAQGVRINSLHPGYIETPLLKALDEATLAALKGLHAIGRLGRPEEIAHAACFL
HHHHHEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LSEGASFMCGSAMVVDGGYTAA
HHCCCCEEECCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7515041; 12450824 [H]