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The map label for this gene is traR [H]

Identifier: 94310278

GI number: 94310278

Start: 1446803

End: 1447765

Strand: Direct

Name: traR [H]

Synonym: Rmet_1336

Alternate gene names: 94310278

Gene position: 1446803-1447765 (Clockwise)

Preceding gene: 94310277

Following gene: 94310279

Centisome position: 36.83

GC content: 60.64

Gene sequence:

>963_bases
TTGAATAGGAAGGGCACAGTGGAGTTGCGCCACCTTCGATGCTTCATCGCTGTCGCGGAAGAACTCCACTTCGCGCGCGC
CGCCGAGCGGCTACATATCGAGCAGTCGCCATTGTCGCGGGCCATCAAGGAATTGGAGGAGGACTTGGGTGTGCAATTAT
TCGAACGCACCACCCGCAGTACCCGCCTCACCCGCGCGGGCCAGCTCTTCCTGGAACACGTGCCACGCATCTTTACTGCC
TTGCAGCAGGCGCGTGACAGCGTGAAAGCGGTCGCCAATGGTTTCCACGGGCAATTGCGTGTGGCCTTGTCGGATGGCAT
CACGCCTTCGCGCTTACCGGCCTTGCTGGCGCTATGCCGACAAGAGGAGCCCGAGGTCGAAATTCGCTTCTTCGAGGTGC
CGCTGTCGCAGCAGATCAAAGGGCTGCATGATGACCTGTACGACGTGGGATTTGCCCAATCCGATGAAGTGGGCGACGGC
ATCGTCGCTTTGCCCGCCTGGAGCGATGCGTTGATGGTGGCGGTGCCCGCCCGGCATCCGCTGCTGATCCACAAGCGCAT
CCCCTTGGATGAGTTACTGCGCTACCCATTGGTACTGTGCGATCCGCAAGTCTGTGAAGGCCTCGCGAAGCATGTTGAGC
GGGTGCTTCGCCGAGTGGACATGGAGCCGCTGGTCGCGGAGCGAGTTGCCACAAGCGATTTGATGATGGCGTTGGTGTCA
GCGGGCTTCGCACTTGGGTTGGCGGGTGCAGCTCACATTGCCGCCAGTCGTGAATCAGGTGTGGTGGCACGACCTTTGGC
GTCACGCGTGCCACCGCTGACGACCTATTTGCTTCGTCTTGACAGTGATCCGTCCGATGAACTGGCGCGGTTCATTGAGC
GCGTAAAGGCCATCGATCTGCCAGAAACTCCCAGACCCGCACGAGGCCGCAATCCCGATCACCCGGAGGAACTGATGCCA
TGA

Upstream 100 bases:

>100_bases
GGCCCGAGGAGATCGCCCACGCAGCCTGCTTCCTGCTGTCCGAAGGTGCCAGCTTCATGTGCGGCAGCGCCATGGTGGTA
GATGGCGGTTATACGGCGGC

Downstream 100 bases:

>100_bases
AGAAGATCATTCCGTTCTTGCTGGTGGCTGCCTTGACCGCCTGCGGTCAGTCCGAGACACCTCTGAACGCCACCAATTCA
AAGGCAAGGATTCCGACAGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MNRKGTVELRHLRCFIAVAEELHFARAAERLHIEQSPLSRAIKELEEDLGVQLFERTTRSTRLTRAGQLFLEHVPRIFTA
LQQARDSVKAVANGFHGQLRVALSDGITPSRLPALLALCRQEEPEVEIRFFEVPLSQQIKGLHDDLYDVGFAQSDEVGDG
IVALPAWSDALMVAVPARHPLLIHKRIPLDELLRYPLVLCDPQVCEGLAKHVERVLRRVDMEPLVAERVATSDLMMALVS
AGFALGLAGAAHIAASRESGVVARPLASRVPPLTTYLLRLDSDPSDELARFIERVKAIDLPETPRPARGRNPDHPEELMP

Sequences:

>Translated_320_residues
MNRKGTVELRHLRCFIAVAEELHFARAAERLHIEQSPLSRAIKELEEDLGVQLFERTTRSTRLTRAGQLFLEHVPRIFTA
LQQARDSVKAVANGFHGQLRVALSDGITPSRLPALLALCRQEEPEVEIRFFEVPLSQQIKGLHDDLYDVGFAQSDEVGDG
IVALPAWSDALMVAVPARHPLLIHKRIPLDELLRYPLVLCDPQVCEGLAKHVERVLRRVDMEPLVAERVATSDLMMALVS
AGFALGLAGAAHIAASRESGVVARPLASRVPPLTTYLLRLDSDPSDELARFIERVKAIDLPETPRPARGRNPDHPEELMP
>Mature_320_residues
MNRKGTVELRHLRCFIAVAEELHFARAAERLHIEQSPLSRAIKELEEDLGVQLFERTTRSTRLTRAGQLFLEHVPRIFTA
LQQARDSVKAVANGFHGQLRVALSDGITPSRLPALLALCRQEEPEVEIRFFEVPLSQQIKGLHDDLYDVGFAQSDEVGDG
IVALPAWSDALMVAVPARHPLLIHKRIPLDELLRYPLVLCDPQVCEGLAKHVERVLRRVDMEPLVAERVATSDLMMALVS
AGFALGLAGAAHIAASRESGVVARPLASRVPPLTTYLLRLDSDPSDELARFIERVKAIDLPETPRPARGRNPDHPEELMP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=247, Percent_Identity=34.0080971659919, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI2367136, Length=272, Percent_Identity=31.9852941176471, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788887, Length=291, Percent_Identity=30.2405498281787, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI157672245, Length=194, Percent_Identity=32.9896907216495, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1790399, Length=199, Percent_Identity=25.1256281407035, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790208, Length=245, Percent_Identity=26.9387755102041, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87081904, Length=195, Percent_Identity=29.7435897435897, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI145693105, Length=192, Percent_Identity=27.6041666666667, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787601, Length=142, Percent_Identity=30.9859154929577, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788748, Length=243, Percent_Identity=25.1028806584362, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787949, Length=291, Percent_Identity=27.1477663230241, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786713, Length=143, Percent_Identity=36.3636363636364, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787806, Length=301, Percent_Identity=23.2558139534884, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786401, Length=128, Percent_Identity=37.5, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI48994962, Length=141, Percent_Identity=31.2056737588652, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787530, Length=251, Percent_Identity=24.7011952191235, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788297, Length=127, Percent_Identity=32.2834645669291, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87082132, Length=144, Percent_Identity=30.5555555555556, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789173, Length=181, Percent_Identity=32.5966850828729, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787589, Length=168, Percent_Identity=27.9761904761905, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789639, Length=122, Percent_Identity=29.5081967213115, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786448, Length=262, Percent_Identity=26.7175572519084, Blast_Score=61, Evalue=8e-11,
Organism=Escherichia coli, GI1788481, Length=194, Percent_Identity=28.8659793814433, Blast_Score=61, Evalue=9e-11,
Organism=Escherichia coli, GI145693193, Length=121, Percent_Identity=30.5785123966942, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35578; Mature: 35578

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRKGTVELRHLRCFIAVAEELHFARAAERLHIEQSPLSRAIKELEEDLGVQLFERTTRS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHH
TRLTRAGQLFLEHVPRIFTALQQARDSVKAVANGFHGQLRVALSDGITPSRLPALLALCR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHC
QEEPEVEIRFFEVPLSQQIKGLHDDLYDVGFAQSDEVGDGIVALPAWSDALMVAVPARHP
CCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEEECCCCC
LLIHKRIPLDELLRYPLVLCDPQVCEGLAKHVERVLRRVDMEPLVAERVATSDLMMALVS
EEEECCCCHHHHHHCCEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AGFALGLAGAAHIAASRESGVVARPLASRVPPLTTYLLRLDSDPSDELARFIERVKAIDL
HHHHHHHHHHHHHHHCCCCCCEECHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
PETPRPARGRNPDHPEELMP
CCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MNRKGTVELRHLRCFIAVAEELHFARAAERLHIEQSPLSRAIKELEEDLGVQLFERTTRS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHH
TRLTRAGQLFLEHVPRIFTALQQARDSVKAVANGFHGQLRVALSDGITPSRLPALLALCR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHC
QEEPEVEIRFFEVPLSQQIKGLHDDLYDVGFAQSDEVGDGIVALPAWSDALMVAVPARHP
CCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEEECCCCC
LLIHKRIPLDELLRYPLVLCDPQVCEGLAKHVERVLRRVDMEPLVAERVATSDLMMALVS
EEEECCCCHHHHHHCCEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AGFALGLAGAAHIAASRESGVVARPLASRVPPLTTYLLRLDSDPSDELARFIERVKAIDL
HHHHHHHHHHHHHHHCCCCCCEECHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
PETPRPARGRNPDHPEELMP
CCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]