| Definition | Cupriavidus metallidurans CH34 chromosome, complete genome. |
|---|---|
| Accession | NC_007973 |
| Length | 3,928,089 |
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The map label for this gene is relA [H]
Identifier: 94310104
GI number: 94310104
Start: 1267354
End: 1269582
Strand: Direct
Name: relA [H]
Synonym: Rmet_1159
Alternate gene names: 94310104
Gene position: 1267354-1269582 (Clockwise)
Preceding gene: 94310103
Following gene: 335055517
Centisome position: 32.26
GC content: 64.74
Gene sequence:
>2229_bases ATGGTGACATCGACGGAGCTGACGGGGCAGACCGCGGGCGTGCCCGACGCCGGGCTCGTCGAGCGCGCGCTCGCGTATGT GCGCGAGAAGGCCGACGGCGAGAAACCCACGACACTGCCCACCGGCGAGACCGTGCTGTCTCACGCCGAGGGGATGCTGC GTATCCTGGATGGCCTGCGCGTGGACGATGCCGCGCGTGCGGCGGCGTGCCTGTTCCCGATGGTGGCGTTTGTGCCCGGC GTCGAGGCGCACATCGAGGAGCGCTTCGGCGAGGACGTGGCGCGGCTGGTGAAGGGCGTGCGGCAACTGTTGCGGATTGG CGCGATCGCCACGCAGGCCGAGGCCGTCGAAACGTCGAAGTCGCAGGCGGCGGCGCGGCAGGAGCAGGTGGAGGCGCTGC GCAAGATGCTGCTGGCCTTCGCGCAGGACATCCGTGTGGTGCTGGTGCGGCTGGCTTCGCGTCTGCAGACGTTGCGCTGG CTGGCGCAGACCAAGAGCCAGCCGCTGCCAGGCGTGGCGCGCGAAACGCTCGATATCTACGCGCCGCTGGCGAACCGGCT GGGTATCTGGCAGATGAAGTGGGAGCTCGAGGATCTGGCCTTCCGCTTCGAGCAGCCCGAGACCTACAAGCGCATCGCCA AGCTGCTCGACGAAAAACGCATCGAGCGAGAGGGCTATATCTCGCAGGCGATCGCGCGGCTGCAGTCCGAGCTGGCGGCG GCGGGCATTCGCGCCGAAGTGACCGGGCGACCCAAGCACATCTACAGCATCTGGAAGAAGATGCGGGGCAAGGCGCTCGA TTTCGCCGATCTCTACGACGTGCGCGCCTTCCGCGTGATCGTCGACGACATCAAGGACTGCTATACGGTGCTCGGTATCG TGCACCACATCTGGCAACCGATTCCGCGCGAGTTCGACGACTACATTTCGCGGCCGAAGGCGAATGGCTACAAATCCCTG CACACGGTGGTGATCGGCGACGATGGCCGAGCGTTCGAGGTGCAGATCCGTACGCACGAGATGCACCACTTCGCCGAGTA CGGCGTGGCGGCGCACTGGCGCTACAAGGAGGCGGGTGGCAAGGGCTATAGCGGTCAGTTCACGGCGGACAACAGCTACG ACGAGAAAATCGCGTGGCTGCGGCAACTGCTGGCGTGGAAGGATGATGCCGATCATACGGTCACGCACGAGGATTCGCCG TGGGAGCAGCTCAAGCACGCAGCAATCGACGACCACATCTATGTGCTGACGCCGCAGGCGCGTGTGGTGGCGTTGCCCCA GGGCGCCACGCCGGTGGATTTTGCCTACTACCTGCATAGTGACCTCGGTCATCGTTGCCGCGGTGCGCGCGTCGATGGCG CGATGGTGCCGCTCAACACGCCGCTCAAGAACGGGCAGACCGTGGAGATCGTGGCGGTCAAGCAGGGTGGGCCATCGCGT GACTGGCTGAACCCCGAGCTGGGCTACCTGGCCAGCAGCCGCGCGCGCGCCAAGGTGCGTGCATGGTTCAATGCACTCGA CTCTCAGGAGACGATTGCCCAAGGGCGCGCCCTGATCGAAAAGACGTTGCAGCGCGAGGGGAAGACGGCGGTCAATCTCG ACGATCTCGCCACCCGACTCAACTTCAAGACACCCGATGATCTGTTCGCGGCGGTGGCGAAGGAAGAGTTCAGCCTGCGC CACGTGGAGCAGGCGCTGCGGCATCCGGACGGGGAAGTGCAGCCGCAGTTCAGCGAGGAAGAGGCCGTTACCAAGAAGAG TCGCGCCACCAGCGTGGCGCGCGGCGCCAAGAGTGGCGTGCTCGTGGTGGGCGTCGATTCGCTGATGACCCAAATGTCTC GCTGCTGCAAGCCGGCGCCGCCGGACGATATCGTTGGCTTCGTGACTCGTGGTCGGGGTGTGTCGATCCATCGACGCAAC TGCCACACGTTCCAGCAACTGTCGACGCGAGACCCCGAGCGGGTGATCCAGACGGAGTGGGGCAAGCGCAGCGATGCCGT GTATCCCGTGGACATCCAGGTGGAGGCGATCGACCGGCAAGGCTTGCTGCGCGATATTTCCGAAGTGCTTTCGCGCGAAA AGATCAACGTCACGGGTGTGAAGACGCTGTCGAGCAAGGGTGTCGCTCGAATGCAGTTCACGGCGGAGGTTGCCGAGGCC ACGCAACTTCAGCGTGCGATTTCCCTGATCGAAGAAGTGCAGGGGGTGTTGCACGCGAAACGAAAATAA
Upstream 100 bases:
>100_bases ACACCGCCGCGGGCCACCGTCCAGGCGGCGCTGGCCAATCCCGACTACCTGATCGAAGTGGTGGTGACGGCCGCGCTCAA CTGATGCGGGGCGGCAAGAC
Downstream 100 bases:
>100_bases GGTTATACTTGCAGCTTCGCTAGGCTCGTAGCTCAGCTGGTTAGAGCACCACCTTGACATGGTGGGGGTCGTTGGTTCGA GTCCAATCGAGCCTACCAAC
Product: (p)ppGpp synthetase I/GTP pyrophosphokinase
Products: NA
Alternate protein names: (p)ppGpp synthase; ATP:GTP 3'-pyrophosphotransferase; ppGpp synthase I [H]
Number of amino acids: Translated: 742; Mature: 742
Protein sequence:
>742_residues MVTSTELTGQTAGVPDAGLVERALAYVREKADGEKPTTLPTGETVLSHAEGMLRILDGLRVDDAARAAACLFPMVAFVPG VEAHIEERFGEDVARLVKGVRQLLRIGAIATQAEAVETSKSQAAARQEQVEALRKMLLAFAQDIRVVLVRLASRLQTLRW LAQTKSQPLPGVARETLDIYAPLANRLGIWQMKWELEDLAFRFEQPETYKRIAKLLDEKRIEREGYISQAIARLQSELAA AGIRAEVTGRPKHIYSIWKKMRGKALDFADLYDVRAFRVIVDDIKDCYTVLGIVHHIWQPIPREFDDYISRPKANGYKSL HTVVIGDDGRAFEVQIRTHEMHHFAEYGVAAHWRYKEAGGKGYSGQFTADNSYDEKIAWLRQLLAWKDDADHTVTHEDSP WEQLKHAAIDDHIYVLTPQARVVALPQGATPVDFAYYLHSDLGHRCRGARVDGAMVPLNTPLKNGQTVEIVAVKQGGPSR DWLNPELGYLASSRARAKVRAWFNALDSQETIAQGRALIEKTLQREGKTAVNLDDLATRLNFKTPDDLFAAVAKEEFSLR HVEQALRHPDGEVQPQFSEEEAVTKKSRATSVARGAKSGVLVVGVDSLMTQMSRCCKPAPPDDIVGFVTRGRGVSIHRRN CHTFQQLSTRDPERVIQTEWGKRSDAVYPVDIQVEAIDRQGLLRDISEVLSREKINVTGVKTLSSKGVARMQFTAEVAEA TQLQRAISLIEEVQGVLHAKRK
Sequences:
>Translated_742_residues MVTSTELTGQTAGVPDAGLVERALAYVREKADGEKPTTLPTGETVLSHAEGMLRILDGLRVDDAARAAACLFPMVAFVPG VEAHIEERFGEDVARLVKGVRQLLRIGAIATQAEAVETSKSQAAARQEQVEALRKMLLAFAQDIRVVLVRLASRLQTLRW LAQTKSQPLPGVARETLDIYAPLANRLGIWQMKWELEDLAFRFEQPETYKRIAKLLDEKRIEREGYISQAIARLQSELAA AGIRAEVTGRPKHIYSIWKKMRGKALDFADLYDVRAFRVIVDDIKDCYTVLGIVHHIWQPIPREFDDYISRPKANGYKSL HTVVIGDDGRAFEVQIRTHEMHHFAEYGVAAHWRYKEAGGKGYSGQFTADNSYDEKIAWLRQLLAWKDDADHTVTHEDSP WEQLKHAAIDDHIYVLTPQARVVALPQGATPVDFAYYLHSDLGHRCRGARVDGAMVPLNTPLKNGQTVEIVAVKQGGPSR DWLNPELGYLASSRARAKVRAWFNALDSQETIAQGRALIEKTLQREGKTAVNLDDLATRLNFKTPDDLFAAVAKEEFSLR HVEQALRHPDGEVQPQFSEEEAVTKKSRATSVARGAKSGVLVVGVDSLMTQMSRCCKPAPPDDIVGFVTRGRGVSIHRRN CHTFQQLSTRDPERVIQTEWGKRSDAVYPVDIQVEAIDRQGLLRDISEVLSREKINVTGVKTLSSKGVARMQFTAEVAEA TQLQRAISLIEEVQGVLHAKRK >Mature_742_residues MVTSTELTGQTAGVPDAGLVERALAYVREKADGEKPTTLPTGETVLSHAEGMLRILDGLRVDDAARAAACLFPMVAFVPG VEAHIEERFGEDVARLVKGVRQLLRIGAIATQAEAVETSKSQAAARQEQVEALRKMLLAFAQDIRVVLVRLASRLQTLRW LAQTKSQPLPGVARETLDIYAPLANRLGIWQMKWELEDLAFRFEQPETYKRIAKLLDEKRIEREGYISQAIARLQSELAA AGIRAEVTGRPKHIYSIWKKMRGKALDFADLYDVRAFRVIVDDIKDCYTVLGIVHHIWQPIPREFDDYISRPKANGYKSL HTVVIGDDGRAFEVQIRTHEMHHFAEYGVAAHWRYKEAGGKGYSGQFTADNSYDEKIAWLRQLLAWKDDADHTVTHEDSP WEQLKHAAIDDHIYVLTPQARVVALPQGATPVDFAYYLHSDLGHRCRGARVDGAMVPLNTPLKNGQTVEIVAVKQGGPSR DWLNPELGYLASSRARAKVRAWFNALDSQETIAQGRALIEKTLQREGKTAVNLDDLATRLNFKTPDDLFAAVAKEEFSLR HVEQALRHPDGEVQPQFSEEEAVTKKSRATSVARGAKSGVLVVGVDSLMTQMSRCCKPAPPDDIVGFVTRGRGVSIHRRN CHTFQQLSTRDPERVIQTEWGKRSDAVYPVDIQVEAIDRQGLLRDISEVLSREKINVTGVKTLSSKGVARMQFTAEVAEA TQLQRAISLIEEVQGVLHAKRK
Specific function: In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which i
COG id: COG0317
COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ACT domain [H]
Homologues:
Organism=Escherichia coli, GI1789147, Length=726, Percent_Identity=40.771349862259, Blast_Score=558, Evalue=1e-160, Organism=Escherichia coli, GI1790082, Length=680, Percent_Identity=35.1470588235294, Blast_Score=411, Evalue=1e-116,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002912 - InterPro: IPR012675 - InterPro: IPR007685 - InterPro: IPR004811 - InterPro: IPR004095 - InterPro: IPR012676 [H]
Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]
EC number: =2.7.6.5 [H]
Molecular weight: Translated: 82898; Mature: 82898
Theoretical pI: Translated: 8.16; Mature: 8.16
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVTSTELTGQTAGVPDAGLVERALAYVREKADGEKPTTLPTGETVLSHAEGMLRILDGLR CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC VDDAARAAACLFPMVAFVPGVEAHIEERFGEDVARLVKGVRQLLRIGAIATQAEAVETSK CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH SQAAARQEQVEALRKMLLAFAQDIRVVLVRLASRLQTLRWLAQTKSQPLPGVARETLDIY HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH APLANRLGIWQMKWELEDLAFRFEQPETYKRIAKLLDEKRIEREGYISQAIARLQSELAA HHHHHCCCEEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH AGIRAEVTGRPKHIYSIWKKMRGKALDFADLYDVRAFRVIVDDIKDCYTVLGIVHHIWQP CCCCEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC IPREFDDYISRPKANGYKSLHTVVIGDDGRAFEVQIRTHEMHHFAEYGVAAHWRYKEAGG CCHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEEEEEHHHHHHHHHHCCCEEEEEHHCCC KGYSGQFTADNSYDEKIAWLRQLLAWKDDADHTVTHEDSPWEQLKHAAIDDHIYVLTPQA CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCC RVVALPQGATPVDFAYYLHSDLGHRCRGARVDGAMVPLNTPLKNGQTVEIVAVKQGGPSR EEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEEEEEECCCCCC DWLNPELGYLASSRARAKVRAWFNALDSQETIAQGRALIEKTLQREGKTAVNLDDLATRL CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHC NFKTPDDLFAAVAKEEFSLRHVEQALRHPDGEVQPQFSEEEAVTKKSRATSVARGAKSGV CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCE LVVGVDSLMTQMSRCCKPAPPDDIVGFVTRGRGVSIHRRNCHTFQQLSTRDPERVIQTEW EEEEHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEECCCCHHHHHHHCCCHHHHHHHCC GKRSDAVYPVDIQVEAIDRQGLLRDISEVLSREKINVTGVKTLSSKGVARMQFTAEVAEA CCCCCCEEEEEEEEEECCHHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCHHHHHHHHHHH TQLQRAISLIEEVQGVLHAKRK HHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MVTSTELTGQTAGVPDAGLVERALAYVREKADGEKPTTLPTGETVLSHAEGMLRILDGLR CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC VDDAARAAACLFPMVAFVPGVEAHIEERFGEDVARLVKGVRQLLRIGAIATQAEAVETSK CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH SQAAARQEQVEALRKMLLAFAQDIRVVLVRLASRLQTLRWLAQTKSQPLPGVARETLDIY HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH APLANRLGIWQMKWELEDLAFRFEQPETYKRIAKLLDEKRIEREGYISQAIARLQSELAA HHHHHCCCEEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH AGIRAEVTGRPKHIYSIWKKMRGKALDFADLYDVRAFRVIVDDIKDCYTVLGIVHHIWQP CCCCEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC IPREFDDYISRPKANGYKSLHTVVIGDDGRAFEVQIRTHEMHHFAEYGVAAHWRYKEAGG CCHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEEEEEHHHHHHHHHHCCCEEEEEHHCCC KGYSGQFTADNSYDEKIAWLRQLLAWKDDADHTVTHEDSPWEQLKHAAIDDHIYVLTPQA CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCC RVVALPQGATPVDFAYYLHSDLGHRCRGARVDGAMVPLNTPLKNGQTVEIVAVKQGGPSR EEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEEEEEECCCCCC DWLNPELGYLASSRARAKVRAWFNALDSQETIAQGRALIEKTLQREGKTAVNLDDLATRL CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHC NFKTPDDLFAAVAKEEFSLRHVEQALRHPDGEVQPQFSEEEAVTKKSRATSVARGAKSGV CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCE LVVGVDSLMTQMSRCCKPAPPDDIVGFVTRGRGVSIHRRNCHTFQQLSTRDPERVIQTEW EEEEHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEECCCCHHHHHHHCCCHHHHHHHCC GKRSDAVYPVDIQVEAIDRQGLLRDISEVLSREKINVTGVKTLSSKGVARMQFTAEVAEA CCCCCCEEEEEEEEEECCHHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCHHHHHHHHHHH TQLQRAISLIEEVQGVLHAKRK HHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7928955 [H]