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The map label for this gene is yueD [H]

Identifier: 94309980

GI number: 94309980

Start: 1124241

End: 1125011

Strand: Reverse

Name: yueD [H]

Synonym: Rmet_1035

Alternate gene names: 94309980

Gene position: 1125011-1124241 (Counterclockwise)

Preceding gene: 94309981

Following gene: 94309979

Centisome position: 28.64

GC content: 68.35

Gene sequence:

>771_bases
ATGACCACCGGAACGCCCCGCTCCACCCATCTCTACATCGTCACCGGCGCCTCGCGCGGCCTGGGGGCCGCCCTGGTTCG
CGCGCTGCTGGTACCCGGCAACCGCGTAATCGGCGTGGCGCGCAGCCGCAACCCCGAGCTCGAGGCCGAGGCTACGGCCA
GCGGCGTGCGCGTGGCCTGGCATCTGCAGGATCTGTCGCAGCCTGGCCCGTCGGCCGGCTGGCTGGCGAGCGTGCTCGAT
GCCGTGGAAGAGGCGCCCGCCAGCATCACCCTGATCCTGAACGCCGGGGTCGTCGAGCCGATCGGTCCGATCACGCAACT
GCATGACAGCACGCTGGTGCCGCATCTGCAGACCAACCTGGTCACGCCGATGACCATGACCGGTGCGTTCATCGAACATA
CGGTGCGCTTCGATTGCCCGCGCAAGGTGCTGGCAATCTCGTCGGGCGCCGCGCGCAACCCCGTACCGGGGTGGTCTGCC
TACTGCGCCGGCAAGGCTGGCCTGGACATGTTCATCCGCTCGGTGAACACCGAGTACGCGAGCGTGCCCGAGCCGCGCAC
CTTGCGCGCCGTGGCGCTGGCGCCGGGCGTGGTGGATACCGGAATGCAGGAAACCATCCGCGGCGCGGATTTCGCCCAGG
TGCAACGCTTCCGCGACCTCAAGGACAACGAACAGCTCGCCTCGCCTGACGATACCGCCCGGCGCATCGTGGCCTATCTG
GCCCGTCCCGATTTCGGCACCACCGAACTCGACGACATCCGCAAATACTGA

Upstream 100 bases:

>100_bases
GCCGAAGATTGCAGATAGACGTCGCCGCGCAATGTCCCCGGACAAACTCGGGGCCTGCGCGGTGATTCCGATGCCATCTC
ACTGAACAAGGTCCACTCAC

Downstream 100 bases:

>100_bases
ACCGATACATTGAACCGAACCCGCGCGACGCTCCGCGCCGCGCGATCGAACCTCACATCATGACCGAACCGACCCGCGCC
CAAGCCGCCACGCCCACCAC

Product: short chain dehydrogenase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MTTGTPRSTHLYIVTGASRGLGAALVRALLVPGNRVIGVARSRNPELEAEATASGVRVAWHLQDLSQPGPSAGWLASVLD
AVEEAPASITLILNAGVVEPIGPITQLHDSTLVPHLQTNLVTPMTMTGAFIEHTVRFDCPRKVLAISSGAARNPVPGWSA
YCAGKAGLDMFIRSVNTEYASVPEPRTLRAVALAPGVVDTGMQETIRGADFAQVQRFRDLKDNEQLASPDDTARRIVAYL
ARPDFGTTELDDIRKY

Sequences:

>Translated_256_residues
MTTGTPRSTHLYIVTGASRGLGAALVRALLVPGNRVIGVARSRNPELEAEATASGVRVAWHLQDLSQPGPSAGWLASVLD
AVEEAPASITLILNAGVVEPIGPITQLHDSTLVPHLQTNLVTPMTMTGAFIEHTVRFDCPRKVLAISSGAARNPVPGWSA
YCAGKAGLDMFIRSVNTEYASVPEPRTLRAVALAPGVVDTGMQETIRGADFAQVQRFRDLKDNEQLASPDDTARRIVAYL
ARPDFGTTELDDIRKY
>Mature_255_residues
TTGTPRSTHLYIVTGASRGLGAALVRALLVPGNRVIGVARSRNPELEAEATASGVRVAWHLQDLSQPGPSAGWLASVLDA
VEEAPASITLILNAGVVEPIGPITQLHDSTLVPHLQTNLVTPMTMTGAFIEHTVRFDCPRKVLAISSGAARNPVPGWSAY
CAGKAGLDMFIRSVNTEYASVPEPRTLRAVALAPGVVDTGMQETIRGADFAQVQRFRDLKDNEQLASPDDTARRIVAYLA
RPDFGTTELDDIRKY

Specific function: Reduces benzil stereospecifically to (S)-benzoin. Can also reduces 1-phenyl-1,2-propanedione, 1,4-naphthoquinone, 1-(4- methyl-phenyl)-2-phenyl-ethane-1,2-dione, 1-(4-fluoro-phenyl)-2- phenyl-ethane-1,2-dione, methyl benzoylformate, p- nitrobenzaldehyde i

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4507185, Length=264, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6322226, Length=223, Percent_Identity=29.5964125560538, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322227, Length=231, Percent_Identity=25.974025974026, Blast_Score=76, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 27392; Mature: 27260

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTGTPRSTHLYIVTGASRGLGAALVRALLVPGNRVIGVARSRNPELEAEATASGVRVAW
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHCCCCEEEEE
HLQDLSQPGPSAGWLASVLDAVEEAPASITLILNAGVVEPIGPITQLHDSTLVPHLQTNL
EEHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHCCCCCCCHHHHCC
VTPMTMTGAFIEHTVRFDCPRKVLAISSGAARNPVPGWSAYCAGKAGLDMFIRSVNTEYA
CCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCHHH
SVPEPRTLRAVALAPGVVDTGMQETIRGADFAQVQRFRDLKDNEQLASPDDTARRIVAYL
CCCCCCCEEEEEECCCHHHCCHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
ARPDFGTTELDDIRKY
HCCCCCCCCHHHHHCC
>Mature Secondary Structure 
TTGTPRSTHLYIVTGASRGLGAALVRALLVPGNRVIGVARSRNPELEAEATASGVRVAW
CCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHCCCCEEEEE
HLQDLSQPGPSAGWLASVLDAVEEAPASITLILNAGVVEPIGPITQLHDSTLVPHLQTNL
EEHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHCCCCCCCHHHHCC
VTPMTMTGAFIEHTVRFDCPRKVLAISSGAARNPVPGWSAYCAGKAGLDMFIRSVNTEYA
CCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCHHH
SVPEPRTLRAVALAPGVVDTGMQETIRGADFAQVQRFRDLKDNEQLASPDDTARRIVAYL
CCCCCCCEEEEEECCCHHHCCHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
ARPDFGTTELDDIRKY
HCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11745140; 11796169 [H]