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The map label for this gene is iscU [H]

Identifier: 94309971

GI number: 94309971

Start: 1116608

End: 1117009

Strand: Direct

Name: iscU [H]

Synonym: Rmet_1026

Alternate gene names: 94309971

Gene position: 1116608-1117009 (Clockwise)

Preceding gene: 94309970

Following gene: 94309972

Centisome position: 28.43

GC content: 60.95

Gene sequence:

>402_bases
ATGTCTTACAGCAACAAGGTTCTCGACCACTATGAAAATCCGCGTAACGTCGGTTCGTTCGACAAGAACGACGACGCGGT
GGGTACCGGCATGGTCGGCGCCCCGGCCTGCGGCGACGTGATGAAGCTGCAGATCAAGGTGAACGAGGCGGGCGTGATCG
AGGACGCCAAGTTCAAGACCTATGGTTGTGGTTCGGCGATCGCCTCGTCGTCGCTGGTGACCGAGTGGGTCAAGGGCAAG
ACCGTGGACCAGGCGCTGGAGATCAAGAACACCCAGATCGCCGAGGAACTGGCTCTGCCGCCGGTGAAGATCCACTGCTC
GATCCTCGCCGAGGACGCCATCAAGGCGGCCGTCGATGATTACAAGAAGAAGCACCCGGGCGCCGAGCAGAAGGCTGCCT
GA

Upstream 100 bases:

>100_bases
AGGACGGCGTCGACCTGAATTCGATCCAGTGGGCCGCGCACTGATTGCGGCACACGTAAAAAGAACAACCCCATTAAAAG
ATTGATTAGAGGTAGCCAAA

Downstream 100 bases:

>100_bases
TCCGGCGTAGACGGTTTGCATGACCGCGCGTGGCAAGTGGGTCGCGCGCGGTGTTCGACAGCAAGGCAAAGATGATCTCA
ATGACCGAAAAGGCGGCCAA

Product: scaffold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MSYSNKVLDHYENPRNVGSFDKNDDAVGTGMVGAPACGDVMKLQIKVNEAGVIEDAKFKTYGCGSAIASSSLVTEWVKGK
TVDQALEIKNTQIAEELALPPVKIHCSILAEDAIKAAVDDYKKKHPGAEQKAA

Sequences:

>Translated_133_residues
MSYSNKVLDHYENPRNVGSFDKNDDAVGTGMVGAPACGDVMKLQIKVNEAGVIEDAKFKTYGCGSAIASSSLVTEWVKGK
TVDQALEIKNTQIAEELALPPVKIHCSILAEDAIKAAVDDYKKKHPGAEQKAA
>Mature_132_residues
SYSNKVLDHYENPRNVGSFDKNDDAVGTGMVGAPACGDVMKLQIKVNEAGVIEDAKFKTYGCGSAIASSSLVTEWVKGKT
VDQALEIKNTQIAEELALPPVKIHCSILAEDAIKAAVDDYKKKHPGAEQKAA

Specific function: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (Potential) [H]

COG id: COG0822

COG function: function code C; NifU homolog involved in Fe-S cluster formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nifU family [H]

Homologues:

Organism=Homo sapiens, GI56699456, Length=123, Percent_Identity=76.4227642276423, Blast_Score=200, Evalue=3e-52,
Organism=Homo sapiens, GI24307953, Length=123, Percent_Identity=75.609756097561, Blast_Score=196, Evalue=4e-51,
Organism=Escherichia coli, GI1788878, Length=125, Percent_Identity=82.4, Blast_Score=220, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI17543474, Length=123, Percent_Identity=72.3577235772358, Blast_Score=194, Evalue=8e-51,
Organism=Saccharomyces cerevisiae, GI6325122, Length=124, Percent_Identity=70.9677419354839, Blast_Score=186, Evalue=8e-49,
Organism=Saccharomyces cerevisiae, GI6324800, Length=123, Percent_Identity=69.9186991869919, Blast_Score=184, Evalue=3e-48,
Organism=Drosophila melanogaster, GI21355597, Length=123, Percent_Identity=74.7967479674797, Blast_Score=195, Evalue=7e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011339
- InterPro:   IPR002871 [H]

Pfam domain/function: PF01592 NifU_N [H]

EC number: NA

Molecular weight: Translated: 14208; Mature: 14077

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSNKVLDHYENPRNVGSFDKNDDAVGTGMVGAPACGDVMKLQIKVNEAGVIEDAKFKT
CCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEECCCCCC
YGCGSAIASSSLVTEWVKGKTVDQALEIKNTQIAEELALPPVKIHCSILAEDAIKAAVDD
CCCCHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHH
YKKKHPGAEQKAA
HHHHCCCCCCCCC
>Mature Secondary Structure 
SYSNKVLDHYENPRNVGSFDKNDDAVGTGMVGAPACGDVMKLQIKVNEAGVIEDAKFKT
CCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEECCCCCC
YGCGSAIASSSLVTEWVKGKTVDQALEIKNTQIAEELALPPVKIHCSILAEDAIKAAVDD
CCCCHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHH
YKKKHPGAEQKAA
HHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]