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The map label for this gene is ygfU [H]

Identifier: 94309828

GI number: 94309828

Start: 966824

End: 968230

Strand: Reverse

Name: ygfU [H]

Synonym: Rmet_0883

Alternate gene names: 94309828

Gene position: 968230-966824 (Counterclockwise)

Preceding gene: 94309829

Following gene: 94309827

Centisome position: 24.65

GC content: 63.82

Gene sequence:

>1407_bases
ATGAATTCCGCAAGCACCACGGTCCCCACGGATCTCACAAACGAGCGGTTGCCCTCCGGGCGATTGCTTGCCCTGGGCCT
GCAGCACGTGCTGGTGATGTATGCCGGCACGGTTGCGGTTCCGCTGATCGTCGGCGGTGCGCTCAAGCTTCCCAAGGATC
AACTCGCGTTCCTGATCAACGCCGACCTGTTCGCGGCTGGCCTGGCCACGCTGATCCAGGCCTTCGGCTTCTGGAAATTC
GGCATCCGCATGCCGGTGATGATGGGTGTCACGTTCGCGTCGGTGGCGCCGATGATCGCCATCGGCAACGATCCCAACGT
CGGGCTGCTCGGCATCTACGGCGCGGTAATCGCGTCCGGTATCTTCGGCATATTGATCGCGCCGATGATGGGCCGGATGC
TGGGACTGTTCCCGCCCGTGGTAACCGGCACGGTGATCACGCTGATTGGCGTGTCGCTGATGCGGGTGGGTATCAACTGG
GCCGGTGGCGGGCAGCCGACCACGCGCGCCGTGATCGACGGCGTGGCAAAGGAAGTGCCCAACCTCGCTTACGGTGACCT
CAGCAACCTGGCCATCGCGGGCCTGGTGCTCGCCGTCATCCTGCTGCTGAGCAAATACGGTCGTGGCCTGGTGGCCAACT
GCGCGGTGCTGCTCGGCATCATCATCGGCACGCTGGTGGCGATGGCATTGGGCAAGGTCTCGTTCGAAGGCCTCAACGAA
GCCAGCTACGTCGCCGTGATCACCCCACTGCATTTCGGCATCCCGAAGTTCGAACTCACCGCCATCCTCTCGATGTGCAT
CGTGATGCTGATCACGCTGGTAGAGTCGACTGGCATGTTCCTGGCCCTGTCCGACATCACCGGCCGCAAGCTCAGCCGTG
ACGACCTGACCGCCGGCCTGCGCGCAGACGGCCTGGGCACCGTGATCGGCGGTATCTTCAACACCTTCCCGTACACGTCG
TTCTCGCAGAACGTTGGCCTGGTCACGGTGACCGGCGTGCGCTCGCGCTACGTCGCCGCGGCGGGTGGCTTGATCCTGAT
CGCGTTCGGCCTGTTCCCGAAGATGGCCCACGTGGTGGCCTCGGTGCCGCAGTTCGTGCTGGGTGGCGCAGGTATCGTGA
TGTTCGGCATGGTGGCCGCCACCGGCATCCGCATCCTCGGTTCGTGTGATTTCAATCGCAACCGCCACAATCTCTTCATC
GTTGCGATCTCGATCGGCTTCGGCATGATCCCGACGCTGTCGCCGACGCTGTTCCAGTACCTGCCCAAGTGGACCGACCC
GTTCACCCACAGCGGCATCGTGCTGGGCACCATCGTCGCCGTGGCGCTGAACCTGTTCTTCAACGGTATCCAGTCGGCCG
AGGAAGCCATGCGCAATGCCGCCGCGAACTCGCACGGCACGGAGTGA

Upstream 100 bases:

>100_bases
GTCATCGACGGAAGTCCACCAAAAAGAGACACCGGCGAATGGCCAGGAAAAAAACCCGGCGCGCGTTCCCATCCAAATCC
AAAGGAGAGGAGACACACCC

Downstream 100 bases:

>100_bases
TTCCGAACAATTCAACTACAACAATCAATAGCGACAATCTGACACCGACAATCGATACCGATCGATGTCAGATTGTCAAG
CCCTACGGGAGCGTTTCTGG

Product: transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MNSASTTVPTDLTNERLPSGRLLALGLQHVLVMYAGTVAVPLIVGGALKLPKDQLAFLINADLFAAGLATLIQAFGFWKF
GIRMPVMMGVTFASVAPMIAIGNDPNVGLLGIYGAVIASGIFGILIAPMMGRMLGLFPPVVTGTVITLIGVSLMRVGINW
AGGGQPTTRAVIDGVAKEVPNLAYGDLSNLAIAGLVLAVILLLSKYGRGLVANCAVLLGIIIGTLVAMALGKVSFEGLNE
ASYVAVITPLHFGIPKFELTAILSMCIVMLITLVESTGMFLALSDITGRKLSRDDLTAGLRADGLGTVIGGIFNTFPYTS
FSQNVGLVTVTGVRSRYVAAAGGLILIAFGLFPKMAHVVASVPQFVLGGAGIVMFGMVAATGIRILGSCDFNRNRHNLFI
VAISIGFGMIPTLSPTLFQYLPKWTDPFTHSGIVLGTIVAVALNLFFNGIQSAEEAMRNAAANSHGTE

Sequences:

>Translated_468_residues
MNSASTTVPTDLTNERLPSGRLLALGLQHVLVMYAGTVAVPLIVGGALKLPKDQLAFLINADLFAAGLATLIQAFGFWKF
GIRMPVMMGVTFASVAPMIAIGNDPNVGLLGIYGAVIASGIFGILIAPMMGRMLGLFPPVVTGTVITLIGVSLMRVGINW
AGGGQPTTRAVIDGVAKEVPNLAYGDLSNLAIAGLVLAVILLLSKYGRGLVANCAVLLGIIIGTLVAMALGKVSFEGLNE
ASYVAVITPLHFGIPKFELTAILSMCIVMLITLVESTGMFLALSDITGRKLSRDDLTAGLRADGLGTVIGGIFNTFPYTS
FSQNVGLVTVTGVRSRYVAAAGGLILIAFGLFPKMAHVVASVPQFVLGGAGIVMFGMVAATGIRILGSCDFNRNRHNLFI
VAISIGFGMIPTLSPTLFQYLPKWTDPFTHSGIVLGTIVAVALNLFFNGIQSAEEAMRNAAANSHGTE
>Mature_468_residues
MNSASTTVPTDLTNERLPSGRLLALGLQHVLVMYAGTVAVPLIVGGALKLPKDQLAFLINADLFAAGLATLIQAFGFWKF
GIRMPVMMGVTFASVAPMIAIGNDPNVGLLGIYGAVIASGIFGILIAPMMGRMLGLFPPVVTGTVITLIGVSLMRVGINW
AGGGQPTTRAVIDGVAKEVPNLAYGDLSNLAIAGLVLAVILLLSKYGRGLVANCAVLLGIIIGTLVAMALGKVSFEGLNE
ASYVAVITPLHFGIPKFELTAILSMCIVMLITLVESTGMFLALSDITGRKLSRDDLTAGLRADGLGTVIGGIFNTFPYTS
FSQNVGLVTVTGVRSRYVAAAGGLILIAFGLFPKMAHVVASVPQFVLGGAGIVMFGMVAATGIRILGSCDFNRNRHNLFI
VAISIGFGMIPTLSPTLFQYLPKWTDPFTHSGIVLGTIVAVALNLFFNGIQSAEEAMRNAAANSHGTE

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680143, Length=479, Percent_Identity=24.6346555323591, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI44680148, Length=172, Percent_Identity=31.3953488372093, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI40316845, Length=172, Percent_Identity=31.3953488372093, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI44680145, Length=171, Percent_Identity=30.9941520467836, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI87082181, Length=464, Percent_Identity=53.2327586206897, Blast_Score=479, Evalue=1e-136,
Organism=Escherichia coli, GI1790087, Length=447, Percent_Identity=31.7673378076063, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI87082178, Length=481, Percent_Identity=28.8981288981289, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1788843, Length=404, Percent_Identity=26.7326732673267, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI87081818, Length=428, Percent_Identity=27.803738317757, Blast_Score=116, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17558856, Length=451, Percent_Identity=24.6119733924612, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71993493, Length=424, Percent_Identity=22.4056603773585, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17541904, Length=429, Percent_Identity=21.4452214452214, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17542260, Length=173, Percent_Identity=26.0115606936416, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356175, Length=436, Percent_Identity=25.4587155963303, Blast_Score=96, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 48769; Mature: 48769

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSASTTVPTDLTNERLPSGRLLALGLQHVLVMYAGTVAVPLIVGGALKLPKDQLAFLIN
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ADLFAAGLATLIQAFGFWKFGIRMPVMMGVTFASVAPMIAIGNDPNVGLLGIYGAVIASG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHH
IFGILIAPMMGRMLGLFPPVVTGTVITLIGVSLMRVGINWAGGGQPTTRAVIDGVAKEVP
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCC
NLAYGDLSNLAIAGLVLAVILLLSKYGRGLVANCAVLLGIIIGTLVAMALGKVSFEGLNE
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ASYVAVITPLHFGIPKFELTAILSMCIVMLITLVESTGMFLALSDITGRKLSRDDLTAGL
CCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHCCC
RADGLGTVIGGIFNTFPYTSFSQNVGLVTVTGVRSRYVAAAGGLILIAFGLFPKMAHVVA
CCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHH
SVPQFVLGGAGIVMFGMVAATGIRILGSCDFNRNRHNLFIVAISIGFGMIPTLSPTLFQY
HHHHHHHCCCHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHH
LPKWTDPFTHSGIVLGTIVAVALNLFFNGIQSAEEAMRNAAANSHGTE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure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CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]