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The map label for this gene is dctD [H]

Identifier: 94309175

GI number: 94309175

Start: 245002

End: 246336

Strand: Direct

Name: dctD [H]

Synonym: Rmet_0230

Alternate gene names: 94309175

Gene position: 245002-246336 (Clockwise)

Preceding gene: 94309174

Following gene: 94309176

Centisome position: 6.24

GC content: 67.42

Gene sequence:

>1335_bases
ATGATTGCGATGCAGGACGGATTGCGTGTGCTGTTCGTCGAGGACGAACCACTGGTGCGTCAGGCGACGGCGCAGAGCCT
GGAACTGGCTGGCTTCTCGGTGCTGGCGCTGCCTTCGGCCGAAGCGGCGATGCCGCATCTTGGCGCGGATTTTCCCGGGG
TGCTGGTTACCGATGTGCGCCTGTCCGGCGCGAGCGGGCTGGATCTGCTGCAGCACTGCCGCAATGCCGCGCCGGGCGTG
CCGGTGATCCTGGTCACGGGGCACGGCGATATCACGATGGCGGTGCAGGCGATGCGCGAGGGCGCCTATGACTTCATCGA
GAAGCCGTTCGGCGCGGATCGTCTGACCGAAACGGTGCGCCGTGCGCTCGAGCGCCGCGCGCTCGAGCTGGAGAACCACG
CGCTGCGCCGCGAGCTGGCTGGCCCGGCTGCCGGCACGCGGATCATCGGCCGGTCGCCGGCGATCGCGCAGGTGCGCGAC
CTGATCGCCAATGTGGCGGCTACCGATGTGCCGGTGATGATCAACGGCGAGACCGGTACGGGCAAGGAACTCGTGGCGCG
GAGCCTGCACGCGCTCTCCACGCGGCGTGACCAACCCTTCATCGCGCTGAACTGTGGTGCCGTGCCAGAGTCGATTTTCG
AGAGCGAGATGTTCGGCCACGAGGCCGGCGCATTTACCGGCGCGGGCAAGCGGCGCGTGGGCAAGCTCGAACATGCGTCG
GGTGGCACCCTGTTCCTCGACGAGATCGAGAGCATGCCGCTGGCCTTGCAGGTGAAGCTGCTGCGCGTGCTGCAGGAGGG
CACGCTGGAGCGGCTCGGCTCGAATACGTCGATACCCATCGACGTGCGCATCATCGCGGCTTCGAAGGGCGACATGGAAG
CACTGGTGGCGCAAGGTACGTTCCGGCAGGATCTGCTGTACCGGCTCAACGTGGTGACGATTCCGCTACCGCCGCTGCGC
GAGCGGCGCGAGGACATCGTGCCGCTGTTCGAGCACTTCATGCTCGTTGCCGCCGTGCGCTATCAGCGGCCGGCGCCGAT
TCTGTCCGAGATGCAGCGCCAGCAACTGATGCAACGGCCCTGGCCCGGCAATGTGCGGGAACTGCGCAACGCGGCAGATC
GACTGGTGCTGGGCGTGCCGGAAGGCGGGCACGCCGGCGGCAAGGCGGATCCCGTTGACGAATCGACGCCGCTGCGCGAG
CGGATGGAGCGCTACGAGCGCGCCGTGATCGCCGATACGCTGGCCCGCACGGGCGGTGCGGTCAGCCAGGCAGCGGACCT
GCTGCAAGTGGGCAAGGCGACGCTTTACGACAAGATCAAACGCTACGGACTGTAA

Upstream 100 bases:

>100_bases
CGAGGGCGGCGGCGCGGAATTCGTCGTGACACTGCGACGCTCGCGCCAGACGGCCACGGCGTGAGGCGCATGAACGGCGT
CAAGGATGACAGGTAAAGAC

Downstream 100 bases:

>100_bases
CGGCCGTACTCGGGGCAGGCGGGGGTCGGTACACTCTGGCCCGGCTCTCTTCCCCGGCTTCCTGTCCCGCGATATCCCGC
GAGCGGAATAACGGCAGGGC

Product: response regulator of C4-dicarboxylate transportsystem

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MIAMQDGLRVLFVEDEPLVRQATAQSLELAGFSVLALPSAEAAMPHLGADFPGVLVTDVRLSGASGLDLLQHCRNAAPGV
PVILVTGHGDITMAVQAMREGAYDFIEKPFGADRLTETVRRALERRALELENHALRRELAGPAAGTRIIGRSPAIAQVRD
LIANVAATDVPVMINGETGTGKELVARSLHALSTRRDQPFIALNCGAVPESIFESEMFGHEAGAFTGAGKRRVGKLEHAS
GGTLFLDEIESMPLALQVKLLRVLQEGTLERLGSNTSIPIDVRIIAASKGDMEALVAQGTFRQDLLYRLNVVTIPLPPLR
ERREDIVPLFEHFMLVAAVRYQRPAPILSEMQRQQLMQRPWPGNVRELRNAADRLVLGVPEGGHAGGKADPVDESTPLRE
RMERYERAVIADTLARTGGAVSQAADLLQVGKATLYDKIKRYGL

Sequences:

>Translated_444_residues
MIAMQDGLRVLFVEDEPLVRQATAQSLELAGFSVLALPSAEAAMPHLGADFPGVLVTDVRLSGASGLDLLQHCRNAAPGV
PVILVTGHGDITMAVQAMREGAYDFIEKPFGADRLTETVRRALERRALELENHALRRELAGPAAGTRIIGRSPAIAQVRD
LIANVAATDVPVMINGETGTGKELVARSLHALSTRRDQPFIALNCGAVPESIFESEMFGHEAGAFTGAGKRRVGKLEHAS
GGTLFLDEIESMPLALQVKLLRVLQEGTLERLGSNTSIPIDVRIIAASKGDMEALVAQGTFRQDLLYRLNVVTIPLPPLR
ERREDIVPLFEHFMLVAAVRYQRPAPILSEMQRQQLMQRPWPGNVRELRNAADRLVLGVPEGGHAGGKADPVDESTPLRE
RMERYERAVIADTLARTGGAVSQAADLLQVGKATLYDKIKRYGL
>Mature_444_residues
MIAMQDGLRVLFVEDEPLVRQATAQSLELAGFSVLALPSAEAAMPHLGADFPGVLVTDVRLSGASGLDLLQHCRNAAPGV
PVILVTGHGDITMAVQAMREGAYDFIEKPFGADRLTETVRRALERRALELENHALRRELAGPAAGTRIIGRSPAIAQVRD
LIANVAATDVPVMINGETGTGKELVARSLHALSTRRDQPFIALNCGAVPESIFESEMFGHEAGAFTGAGKRRVGKLEHAS
GGTLFLDEIESMPLALQVKLLRVLQEGTLERLGSNTSIPIDVRIIAASKGDMEALVAQGTFRQDLLYRLNVVTIPLPPLR
ERREDIVPLFEHFMLVAAVRYQRPAPILSEMQRQQLMQRPWPGNVRELRNAADRLVLGVPEGGHAGGKADPVDESTPLRE
RMERYERAVIADTLARTGGAVSQAADLLQVGKATLYDKIKRYGL

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=453, Percent_Identity=39.9558498896247, Blast_Score=325, Evalue=4e-90,
Organism=Escherichia coli, GI1790299, Length=473, Percent_Identity=38.4778012684989, Blast_Score=305, Evalue=5e-84,
Organism=Escherichia coli, GI1790437, Length=446, Percent_Identity=38.3408071748879, Blast_Score=287, Evalue=9e-79,
Organism=Escherichia coli, GI1788905, Length=444, Percent_Identity=38.5135135135135, Blast_Score=278, Evalue=4e-76,
Organism=Escherichia coli, GI87082117, Length=341, Percent_Identity=42.2287390029325, Blast_Score=242, Evalue=4e-65,
Organism=Escherichia coli, GI1789233, Length=320, Percent_Identity=40.625, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1789087, Length=327, Percent_Identity=43.4250764525994, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI87082152, Length=319, Percent_Identity=42.0062695924765, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI87081872, Length=230, Percent_Identity=46.9565217391304, Blast_Score=221, Evalue=8e-59,
Organism=Escherichia coli, GI1786524, Length=318, Percent_Identity=39.622641509434, Blast_Score=214, Evalue=7e-57,
Organism=Escherichia coli, GI1787583, Length=319, Percent_Identity=36.3636363636364, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI87081858, Length=304, Percent_Identity=32.8947368421053, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789828, Length=244, Percent_Identity=35.655737704918, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789809, Length=127, Percent_Identity=30.7086614173228, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 48193; Mature: 48193

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAMQDGLRVLFVEDEPLVRQATAQSLELAGFSVLALPSAEAAMPHLGADFPGVLVTDVR
CCCCCCCCEEEEECCCCHHHHHHHHHHHHCCEEEEECCCHHHCCCCCCCCCCCEEEEEEE
LSGASGLDLLQHCRNAAPGVPVILVTGHGDITMAVQAMREGAYDFIEKPFGADRLTETVR
ECCCCCHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCHHHHHHCCCCHHHHHHHHH
RALERRALELENHALRRELAGPAAGTRIIGRSPAIAQVRDLIANVAATDVPVMINGETGT
HHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCCC
GKELVARSLHALSTRRDQPFIALNCGAVPESIFESEMFGHEAGAFTGAGKRRVGKLEHAS
CHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCC
GGTLFLDEIESMPLALQVKLLRVLQEGTLERLGSNTSIPIDVRIIAASKGDMEALVAQGT
CCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHCCC
FRQDLLYRLNVVTIPLPPLRERREDIVPLFEHFMLVAAVRYQRPAPILSEMQRQQLMQRP
HHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
WPGNVRELRNAADRLVLGVPEGGHAGGKADPVDESTPLRERMERYERAVIADTLARTGGA
CCCCHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCH
VSQAADLLQVGKATLYDKIKRYGL
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIAMQDGLRVLFVEDEPLVRQATAQSLELAGFSVLALPSAEAAMPHLGADFPGVLVTDVR
CCCCCCCCEEEEECCCCHHHHHHHHHHHHCCEEEEECCCHHHCCCCCCCCCCCEEEEEEE
LSGASGLDLLQHCRNAAPGVPVILVTGHGDITMAVQAMREGAYDFIEKPFGADRLTETVR
ECCCCCHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCHHHHHHCCCCHHHHHHHHH
RALERRALELENHALRRELAGPAAGTRIIGRSPAIAQVRDLIANVAATDVPVMINGETGT
HHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCCC
GKELVARSLHALSTRRDQPFIALNCGAVPESIFESEMFGHEAGAFTGAGKRRVGKLEHAS
CHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCC
GGTLFLDEIESMPLALQVKLLRVLQEGTLERLGSNTSIPIDVRIIAASKGDMEALVAQGT
CCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHCCC
FRQDLLYRLNVVTIPLPPLRERREDIVPLFEHFMLVAAVRYQRPAPILSEMQRQQLMQRP
HHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
WPGNVRELRNAADRLVLGVPEGGHAGGKADPVDESTPLRERMERYERAVIADTLARTGGA
CCCCHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCH
VSQAADLLQVGKATLYDKIKRYGL
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3671068 [H]