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The map label for this gene is maeB1 [H]

Identifier: 335055643

GI number: 335055643

Start: 3301716

End: 3304301

Strand: Reverse

Name: maeB1 [H]

Synonym: NA

Alternate gene names: 335055643

Gene position: 3304301-3301716 (Counterclockwise)

Preceding gene: 94311981

Following gene: 94311976

Centisome position: 84.12

GC content: 63.42

Gene sequence:

>2586_bases
ATGACGGGGCGGGGAACCTGGGAGGAAACATGCCGCGGAAATTCTGCTGGAGACTCGGCTGGTAAAGCCCATCGGCATGG
GGCATATTGTACCGAAACGCAAAGGTGCCCCAAACAAAAGGCTTATTGTGAAATACTATTTCACAATATAAAATGCACAC
TTCCAAAAGCGCCTACAGCGGAGACAGCGGGTTCGTGGAGCCGGCCCGCGCTCAATCGCCAGCGTTATTCAGTGCGGCTC
CACCGATCGGAAGATGCGCAGATGACAAGCCCTCAGCAGTCCCCGTCCCAAGACGATCTGAAACAGCAGCAGCGTGAGGC
GCTGCGCAAGGCCGCGCTCGAGTACCACGAGTTTCCCACCCCCGGAAAGATCTCGGTCACCCCGACCAAGCCGCTGTCGA
ACCAGCGCGACCTGGCTCTGGCCTATTCGCCGGGTGTGGCGGCAGCGTGTGAGGAAATCGTGGCCAACCAGGCCAATTCG
TTCCGCTACACGGCGCGTGGCAACCTGGTGGCCGTGATCACCAACGGCACCGCCGTGCTGGGTCTGGGCGATATCGGCGC
GGCCGCGTCGAAGCCGGTGATGGAAGGCAAGGCCGGCCTGTTCAAGAAGTTCGCCGGTATCGATGTGTTCGATATCGAAG
TCGACGAGAAAGACCCCGAGAAGCTGGTCGACATCATCGCCTCGCTCGAGCCGACGTTCGGCGGTATCAACCTCGAGGAC
ATCAAGGCGCCGGAGTGCTTCTACGTGGAGCGCAAGCTGCGCGAGCGGATGAAGATCCCCGTCTTCCACGATGACCAGCA
CGGTACCGCGATCGTCGTGGGCGCCGCCGTGATCAACGGCATGCAGGTGGTGGGCAAGGACATCTCGAAGGTGAAGCTGG
TGGCCTCGGGCGCCGGCGCCGCCGCGCTGGCCTGCCTGGACCTGCTCGTCGACCTGGGCCTGCCCATCGAGAACATCTGG
GTGACGGACCTGGCCGGCGTGGTCTACGAAGGCCGTACCGAACTGATGGACCCGGAAAAGGCGCGCTTCTCGCAGAAGAC
CGACAAGCGCAAGCTGGCCGAGGTCATCGAAGGCGCCGACATTTTCCTGGGCCTGTCCGCTGCGGGCGTGCTGAAGCCCG
AGATGGTGCAGAAGATGGCCGACAAGCCGCTGGTGATGGCACTGGCCAACCCGAATCCGGAAATCATGCCGGAACTGGTC
AAGGAAGTCCGTCCGGACGCCGTGATCGCCACGGGCCGCACCGACTATCCGAACCAGGTCAACAACGTCCTCTGCTTCCC
GTTCATCTTCCGTGGCGCGCTCGATTGCGGCGCCACGACGATCACGCGTGAAATGGAAATCGCCGCGGCAAACGCGGTGG
CGGAGCTGGCGCGCCAGGAGCAGAGCGATATCGTCGCGTCGGCCTATGGCATCCAGGACCTGTCGTTCGGCCCCGAATAC
CTGATTCCGAAGCCGTTCGATCCGCGCCTGATCGTCAAGATCGCCCCGGCCGTGGCCGAGGCCGCCGCCAAATCGGGCGT
GGCATCGCGCCCGATCGAGGACATGGACGCGTACCGTCTGCAATTGCAGCAGTTCGTGTACCACTCGGGTACGCTGATGA
AGCCGATCTACGCGGCCGCCCGCAAGGTGCAGAAGGAGAAGAAGCGCATCGTCTTCGCCGAGGGCGAGGAAGAGCGCGTG
CTGCGTGCGGTGCAGGTGATCGTCGACGAGAAGCTGGCCAACCCGATCCTGATCGGCCGCCCGGCCGTGCTGGCTCACCG
CATCGAGCGTTTCGGCCTGCGCCTGCGCATGGGCGAGGACTTCACGGTGGTGAACCCAGAGCACGACGAGCGTTTCCGCG
AATACTCGGACGCGTACTACCGCATGATGGCGCGTGAAGGCATCACGCCGCAGTACGCCAAGCTGGAAATGCGCCGCCGT
ACCACGCTGATCGGCGCGATGCTGGTCGAGAAGGGCGAAGCCGACGGCATGATCTGCGGTACGGTTAGCACCACCGCCGC
CCACCTGCGCTATATCGACCAGGTCATCGGTGGCACAAATTGCGTGTACGCCGCAATGAACGGTCTGGTTCTGCCCGGCC
GCCAGATCTTCCTGGTGGACACGCACGTCAACGTCGATCCCACCGCCGAGCAACTGGCCGAGATCACGATCATGGCTGCG
GAGGAGCTCAAGCGTTTCGGTATCGAGCCGAAGGTGGGTCTGCTGTCGCACTCGAACTTCGGTACGTCGGAAGCGCCGTC
GGCACGCAAGATGCGCGACACGCTGAAGATCCTGCGCGACCGCGCGCCGGACCTCGAGGTGGATGGCGAAATGCATGGCG
ACAGCGCGCTCGACGAAAAGCTGCGCGATTCGCTGGTGCCGGACAGCGCGCTCAAGGGCGAAGCCAATCTGCTCGTGTGC
CCGAACATCGATGCCGCCAACATCTCGTACAACCTGCTCAAGGTGGCGGCTGGCAACAACGTGGCGATCGGCCCGATCCT
GCTGGGCGTGAAGGCGCCGGTCCATATCCTGACGCCTTCGGCAACGGTGCGCCGTATCGTCAATATGACCGCGCTGGTGG
TCGTGGACGCGGCAGCCAAGGTCTGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: fused malic enzyme oxidoreductase; phosphotransacetylase

Products: NA

Alternate protein names: NADP-ME [H]

Number of amino acids: Translated: 861; Mature: 860

Protein sequence:
NA

Sequences:

>Translated_861_residues
MTGRGTWEETCRGNSAGDSAGKAHRHGAYCTETQRCPKQKAYCEILFHNIKCTLPKAPTAETAGSWSRPALNRQRYSVRL
HRSEDAQMTSPQQSPSQDDLKQQQREALRKAALEYHEFPTPGKISVTPTKPLSNQRDLALAYSPGVAAACEEIVANQANS
FRYTARGNLVAVITNGTAVLGLGDIGAAASKPVMEGKAGLFKKFAGIDVFDIEVDEKDPEKLVDIIASLEPTFGGINLED
IKAPECFYVERKLRERMKIPVFHDDQHGTAIVVGAAVINGMQVVGKDISKVKLVASGAGAAALACLDLLVDLGLPIENIW
VTDLAGVVYEGRTELMDPEKARFSQKTDKRKLAEVIEGADIFLGLSAAGVLKPEMVQKMADKPLVMALANPNPEIMPELV
KEVRPDAVIATGRTDYPNQVNNVLCFPFIFRGALDCGATTITREMEIAAANAVAELARQEQSDIVASAYGIQDLSFGPEY
LIPKPFDPRLIVKIAPAVAEAAAKSGVASRPIEDMDAYRLQLQQFVYHSGTLMKPIYAAARKVQKEKKRIVFAEGEEERV
LRAVQVIVDEKLANPILIGRPAVLAHRIERFGLRLRMGEDFTVVNPEHDERFREYSDAYYRMMAREGITPQYAKLEMRRR
TTLIGAMLVEKGEADGMICGTVSTTAAHLRYIDQVIGGTNCVYAAMNGLVLPGRQIFLVDTHVNVDPTAEQLAEITIMAA
EELKRFGIEPKVGLLSHSNFGTSEAPSARKMRDTLKILRDRAPDLEVDGEMHGDSALDEKLRDSLVPDSALKGEANLLVC
PNIDAANISYNLLKVAAGNNVAIGPILLGVKAPVHILTPSATVRRIVNMTALVVVDAAAKV
>Mature_860_residues
TGRGTWEETCRGNSAGDSAGKAHRHGAYCTETQRCPKQKAYCEILFHNIKCTLPKAPTAETAGSWSRPALNRQRYSVRLH
RSEDAQMTSPQQSPSQDDLKQQQREALRKAALEYHEFPTPGKISVTPTKPLSNQRDLALAYSPGVAAACEEIVANQANSF
RYTARGNLVAVITNGTAVLGLGDIGAAASKPVMEGKAGLFKKFAGIDVFDIEVDEKDPEKLVDIIASLEPTFGGINLEDI
KAPECFYVERKLRERMKIPVFHDDQHGTAIVVGAAVINGMQVVGKDISKVKLVASGAGAAALACLDLLVDLGLPIENIWV
TDLAGVVYEGRTELMDPEKARFSQKTDKRKLAEVIEGADIFLGLSAAGVLKPEMVQKMADKPLVMALANPNPEIMPELVK
EVRPDAVIATGRTDYPNQVNNVLCFPFIFRGALDCGATTITREMEIAAANAVAELARQEQSDIVASAYGIQDLSFGPEYL
IPKPFDPRLIVKIAPAVAEAAAKSGVASRPIEDMDAYRLQLQQFVYHSGTLMKPIYAAARKVQKEKKRIVFAEGEEERVL
RAVQVIVDEKLANPILIGRPAVLAHRIERFGLRLRMGEDFTVVNPEHDERFREYSDAYYRMMAREGITPQYAKLEMRRRT
TLIGAMLVEKGEADGMICGTVSTTAAHLRYIDQVIGGTNCVYAAMNGLVLPGRQIFLVDTHVNVDPTAEQLAEITIMAAE
ELKRFGIEPKVGLLSHSNFGTSEAPSARKMRDTLKILRDRAPDLEVDGEMHGDSALDEKLRDSLVPDSALKGEANLLVCP
NIDAANISYNLLKVAAGNNVAIGPILLGVKAPVHILTPSATVRRIVNMTALVVVDAAAKV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Homo sapiens, GI4505143, Length=398, Percent_Identity=24.8743718592965, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI62420882, Length=409, Percent_Identity=24.9388753056235, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI62420880, Length=409, Percent_Identity=24.9388753056235, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI239049447, Length=409, Percent_Identity=24.9388753056235, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI4505145, Length=369, Percent_Identity=27.3712737127371, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI270265879, Length=318, Percent_Identity=28.3018867924528, Blast_Score=74, Evalue=7e-13,
Organism=Escherichia coli, GI1788806, Length=755, Percent_Identity=62.5165562913907, Blast_Score=968, Evalue=0.0,
Organism=Escherichia coli, GI1788635, Length=329, Percent_Identity=32.5227963525836, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1788800, Length=313, Percent_Identity=32.5878594249201, Blast_Score=150, Evalue=4e-37,
Organism=Escherichia coli, GI87081919, Length=457, Percent_Identity=24.945295404814, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17537199, Length=465, Percent_Identity=24.3010752688172, Blast_Score=75, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322823, Length=275, Percent_Identity=27.2727272727273, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281362672, Length=473, Percent_Identity=26.215644820296, Blast_Score=98, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281362674, Length=473, Percent_Identity=26.215644820296, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21356279, Length=473, Percent_Identity=26.215644820296, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24646388, Length=475, Percent_Identity=24.6315789473684, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646386, Length=475, Percent_Identity=24.6315789473684, Blast_Score=82, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015884
- InterPro:   IPR012301
- InterPro:   IPR012302
- InterPro:   IPR012188
- InterPro:   IPR016040
- InterPro:   IPR002505 [H]

Pfam domain/function: PF00390 malic; PF03949 Malic_M; PF01515 PTA_PTB [H]

EC number: =1.1.1.40 [H]

Molecular weight: Translated: 93793; Mature: 93662

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGRGTWEETCRGNSAGDSAGKAHRHGAYCTETQRCPKQKAYCEILFHNIKCTLPKAPTA
CCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCEEECCCCCCC
ETAGSWSRPALNRQRYSVRLHRSEDAQMTSPQQSPSQDDLKQQQREALRKAALEYHEFPT
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
PGKISVTPTKPLSNQRDLALAYSPGVAAACEEIVANQANSFRYTARGNLVAVITNGTAVL
CCEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEECCCEEEEEECCEEEE
GLGDIGAAASKPVMEGKAGLFKKFAGIDVFDIEVDEKDPEKLVDIIASLEPTFGGINLED
EECCCCCCCCCCCCCCCHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHH
IKAPECFYVERKLRERMKIPVFHDDQHGTAIVVGAAVINGMQVVGKDISKVKLVASGAGA
CCCCHHHHHHHHHHHHCCCCCEECCCCCCEEEEHHHHHCCHHHHCCCCHHEEEEECCCCH
AALACLDLLVDLGLPIENIWVTDLAGVVYEGRTELMDPEKARFSQKTDKRKLAEVIEGAD
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCC
IFLGLSAAGVLKPEMVQKMADKPLVMALANPNPEIMPELVKEVRPDAVIATGRTDYPNQV
EEEEECCCCCCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCHHH
NNVLCFPFIFRGALDCGATTITREMEIAAANAVAELARQEQSDIVASAYGIQDLSFGPEY
CCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
LIPKPFDPRLIVKIAPAVAEAAAKSGVASRPIEDMDAYRLQLQQFVYHSGTLMKPIYAAA
CCCCCCCCEEEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
RKVQKEKKRIVFAEGEEERVLRAVQVIVDEKLANPILIGRPAVLAHRIERFGLRLRMGED
HHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCEEEEECCC
FTVVNPEHDERFREYSDAYYRMMAREGITPQYAKLEMRRRTTLIGAMLVEKGEADGMICG
EEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TVSTTAAHLRYIDQVIGGTNCVYAAMNGLVLPGRQIFLVDTHVNVDPTAEQLAEITIMAA
CHHHHHHHHHHHHHHHCCCCEEHHHHCCEECCCCEEEEEEECCCCCCCHHHHHHHHHHHH
EELKRFGIEPKVGLLSHSNFGTSEAPSARKMRDTLKILRDRAPDLEVDGEMHGDSALDEK
HHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHH
LRDSLVPDSALKGEANLLVCPNIDAANISYNLLKVAAGNNVAIGPILLGVKAPVHILTPS
HHHHCCCCCCCCCCCCEEEECCCCCCCCEEEEEEEECCCCEEEHHEEEECCCCEEEECCC
ATVRRIVNMTALVVVDAAAKV
HHHHHHHHHHHHEEEHHHHCC
>Mature Secondary Structure 
TGRGTWEETCRGNSAGDSAGKAHRHGAYCTETQRCPKQKAYCEILFHNIKCTLPKAPTA
CCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCEEECCCCCCC
ETAGSWSRPALNRQRYSVRLHRSEDAQMTSPQQSPSQDDLKQQQREALRKAALEYHEFPT
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
PGKISVTPTKPLSNQRDLALAYSPGVAAACEEIVANQANSFRYTARGNLVAVITNGTAVL
CCEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEECCCEEEEEECCEEEE
GLGDIGAAASKPVMEGKAGLFKKFAGIDVFDIEVDEKDPEKLVDIIASLEPTFGGINLED
EECCCCCCCCCCCCCCCHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHH
IKAPECFYVERKLRERMKIPVFHDDQHGTAIVVGAAVINGMQVVGKDISKVKLVASGAGA
CCCCHHHHHHHHHHHHCCCCCEECCCCCCEEEEHHHHHCCHHHHCCCCHHEEEEECCCCH
AALACLDLLVDLGLPIENIWVTDLAGVVYEGRTELMDPEKARFSQKTDKRKLAEVIEGAD
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCC
IFLGLSAAGVLKPEMVQKMADKPLVMALANPNPEIMPELVKEVRPDAVIATGRTDYPNQV
EEEEECCCCCCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCHHH
NNVLCFPFIFRGALDCGATTITREMEIAAANAVAELARQEQSDIVASAYGIQDLSFGPEY
CCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
LIPKPFDPRLIVKIAPAVAEAAAKSGVASRPIEDMDAYRLQLQQFVYHSGTLMKPIYAAA
CCCCCCCCEEEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
RKVQKEKKRIVFAEGEEERVLRAVQVIVDEKLANPILIGRPAVLAHRIERFGLRLRMGED
HHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCEEEEECCC
FTVVNPEHDERFREYSDAYYRMMAREGITPQYAKLEMRRRTTLIGAMLVEKGEADGMICG
EEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TVSTTAAHLRYIDQVIGGTNCVYAAMNGLVLPGRQIFLVDTHVNVDPTAEQLAEITIMAA
CHHHHHHHHHHHHHHHCCCCEEHHHHCCEECCCCEEEEEEECCCCCCCHHHHHHHHHHHH
EELKRFGIEPKVGLLSHSNFGTSEAPSARKMRDTLKILRDRAPDLEVDGEMHGDSALDEK
HHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHH
LRDSLVPDSALKGEANLLVCPNIDAANISYNLLKVAAGNNVAIGPILLGVKAPVHILTPS
HHHHCCCCCCCCCCCCEEEECCCCCCCCEEEEEEEECCCCEEEHHEEEECCCCEEEECCC
ATVRRIVNMTALVVVDAAAKV
HHHHHHHHHHHHEEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 36376 [H]