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The map label for this gene is gpmA [H]

Identifier: 335055482

GI number: 335055482

Start: 267833

End: 268579

Strand: Reverse

Name: gpmA [H]

Synonym: NA

Alternate gene names: 335055482

Gene position: 268579-267833 (Counterclockwise)

Preceding gene: 94309202

Following gene: 94309195

Centisome position: 6.84

GC content: 65.06

Gene sequence:

>747_bases
ATGTACAAGCTCGTTCTCATCCGCCACGGCGAATCCACGTGGAACCTCGAAAACCGCTTCACCGGCTGGGTCGACGTCGA
CCTGACCGATACGGGCGCCGCGCAGGCCAAACAGGCCGGCACGCTGCTCAAGGAAGCCGGCTTCGCCTTTGACGTGGCCT
ACACCTCCGTGCTCAAGCGCGCCATCCGCACGCTCTGGCACGTGCAAGACGAAATGGACCTGATGTGGATTCCGGTGCGC
AATGAATGGCGCCTGAACGAACGTCACTACGGCGCGCTGGCCGGCCTGAACAAGGCGGAAACGGCCAAGAAGTACGGCGA
CGAGCAGGTGCTGGTGTGGCGCCGCAGCTACGACACGCCGCCGCCCGCGCTGGAGCCGACCGACGAACGTGCCTCTTTCG
GCGACCCGCGCTACGCCAATGTGCCGCGCGCGGAGATCCCGCTGACCGAGTGCCTGAAGGACACGGTGGCCCGCGTGATG
CCGCTGTGGAACGAATCCATTGCTCCCGACATCAAATCCGGCAAGCGCGTGGTGATCGCCGCCCATGGCAACAGCATTCG
CGCCCTCGTAAAGTATCTGGACCAGATTTCGGATGACGATATCGTCGGCCTCAATATCCCCAATGGCACCCCGCTCGTCT
ACGAGCTGGATGCCGACCTGCGCCCCCTGCGCCACTACTACCTGGGCGACCAGGAAGCCATCGCGGCGTCCCTGGCCGCC
GTGGCCAGCCAGGGCAAGGCCCGCTGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: phosphoglyceromutase 1

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:
NA

Sequences:

>Translated_248_residues
MYKLVLIRHGESTWNLENRFTGWVDVDLTDTGAAQAKQAGTLLKEAGFAFDVAYTSVLKRAIRTLWHVQDEMDLMWIPVR
NEWRLNERHYGALAGLNKAETAKKYGDEQVLVWRRSYDTPPPALEPTDERASFGDPRYANVPRAEIPLTECLKDTVARVM
PLWNESIAPDIKSGKRVVIAAHGNSIRALVKYLDQISDDDIVGLNIPNGTPLVYELDADLRPLRHYYLGDQEAIAASLAA
VASQGKAR
>Mature_248_residues
MYKLVLIRHGESTWNLENRFTGWVDVDLTDTGAAQAKQAGTLLKEAGFAFDVAYTSVLKRAIRTLWHVQDEMDLMWIPVR
NEWRLNERHYGALAGLNKAETAKKYGDEQVLVWRRSYDTPPPALEPTDERASFGDPRYANVPRAEIPLTECLKDTVARVM
PLWNESIAPDIKSGKRVVIAAHGNSIRALVKYLDQISDDDIVGLNIPNGTPLVYELDADLRPLRHYYLGDQEAIAASLAA
VASQGKAR

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=253, Percent_Identity=54.5454545454545, Blast_Score=299, Evalue=2e-81,
Organism=Homo sapiens, GI4505753, Length=250, Percent_Identity=57.6, Blast_Score=293, Evalue=1e-79,
Organism=Homo sapiens, GI71274132, Length=250, Percent_Identity=55.6, Blast_Score=280, Evalue=6e-76,
Organism=Homo sapiens, GI4502445, Length=252, Percent_Identity=48.015873015873, Blast_Score=261, Evalue=4e-70,
Organism=Homo sapiens, GI40353764, Length=252, Percent_Identity=48.015873015873, Blast_Score=261, Evalue=4e-70,
Organism=Homo sapiens, GI310129614, Length=162, Percent_Identity=59.8765432098765, Blast_Score=191, Evalue=7e-49,
Organism=Escherichia coli, GI1786970, Length=246, Percent_Identity=64.2276422764228, Blast_Score=327, Evalue=7e-91,
Organism=Saccharomyces cerevisiae, GI6322697, Length=246, Percent_Identity=53.2520325203252, Blast_Score=242, Evalue=4e-65,
Organism=Saccharomyces cerevisiae, GI6324516, Length=294, Percent_Identity=34.3537414965986, Blast_Score=147, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6320183, Length=296, Percent_Identity=31.7567567567568, Blast_Score=139, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24646216, Length=251, Percent_Identity=52.5896414342629, Blast_Score=267, Evalue=4e-72,
Organism=Drosophila melanogaster, GI85725270, Length=251, Percent_Identity=51.792828685259, Blast_Score=256, Evalue=9e-69,
Organism=Drosophila melanogaster, GI85725272, Length=251, Percent_Identity=51.792828685259, Blast_Score=256, Evalue=9e-69,
Organism=Drosophila melanogaster, GI24650981, Length=251, Percent_Identity=51.792828685259, Blast_Score=256, Evalue=9e-69,
Organism=Drosophila melanogaster, GI28571815, Length=251, Percent_Identity=40.6374501992032, Blast_Score=191, Evalue=5e-49,
Organism=Drosophila melanogaster, GI28571817, Length=251, Percent_Identity=40.6374501992032, Blast_Score=190, Evalue=6e-49,
Organism=Drosophila melanogaster, GI24648979, Length=251, Percent_Identity=40.6374501992032, Blast_Score=190, Evalue=9e-49,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 27816; Mature: 27816

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKLVLIRHGESTWNLENRFTGWVDVDLTDTGAAQAKQAGTLLKEAGFAFDVAYTSVLKR
CEEEEEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AIRTLWHVQDEMDLMWIPVRNEWRLNERHYGALAGLNKAETAKKYGDEQVLVWRRSYDTP
HHHHHHHCCCCCCEEEEECCCCEECCCHHHHHHHCCCHHHHHHHCCCCEEEEEEECCCCC
PPALEPTDERASFGDPRYANVPRAEIPLTECLKDTVARVMPLWNESIAPDIKSGKRVVIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
AHGNSIRALVKYLDQISDDDIVGLNIPNGTPLVYELDADLRPLRHYYLGDQEAIAASLAA
ECCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCCHHHHHHHCCCHHHHHHHHHH
VASQGKAR
HHHCCCCC
>Mature Secondary Structure
MYKLVLIRHGESTWNLENRFTGWVDVDLTDTGAAQAKQAGTLLKEAGFAFDVAYTSVLKR
CEEEEEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AIRTLWHVQDEMDLMWIPVRNEWRLNERHYGALAGLNKAETAKKYGDEQVLVWRRSYDTP
HHHHHHHCCCCCCEEEEECCCCEECCCHHHHHHHCCCHHHHHHHCCCCEEEEEEECCCCC
PPALEPTDERASFGDPRYANVPRAEIPLTECLKDTVARVMPLWNESIAPDIKSGKRVVIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
AHGNSIRALVKYLDQISDDDIVGLNIPNGTPLVYELDADLRPLRHYYLGDQEAIAASLAA
ECCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCCHHHHHHHCCCHHHHHHHHHH
VASQGKAR
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA