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The map label for this gene is epd [H]

Identifier: 93006666

GI number: 93006666

Start: 2272635

End: 2273810

Strand: Reverse

Name: epd [H]

Synonym: Pcryo_1842

Alternate gene names: 93006666

Gene position: 2273810-2272635 (Counterclockwise)

Preceding gene: 93006667

Following gene: 93006663

Centisome position: 74.31

GC content: 47.19

Gene sequence:

>1176_bases
ATGCCTGATTTTTCTAGTGCTACCTACCGTTTGACGTCTAATCCTGCTACATCAGGGTTTCATACGACCAGTGACCAGAC
TCAGCCTTTGCGAGTGGCTATCAATGGTTTTGGTCGTATTGGTCGCAATGTATTGCGTGCGTTATTAGAGCGCTTTGAGG
TGCTAGGACGTGCTATTCATGTGGTCGCGATTAATGATTTAGCGCCTGCCGAAACCTTATTACATTTACTGAGGTTCGAT
AGCACACATGGGCGTTTGAGCCAGCTTGGCGTGACAGCGGATATCGTACAAGATGGCTTCACCGATCATAAGCAAAAGCC
CTGTGCGACAGCAAAAAACGATATTCAGCTGTGCTTGACCAAAAATAATCTTACTTACTGCATTCGTTTATTATCAAGAG
AAAACCCAGAGACACTGCCATGGAAAGAGTTGCAGGTCGATGTGGTGCTTGAGTGCACCGGACATTATCGCTCATATGAG
CAGGCAAGCTTGCACATAGAGGCGGGTGCCAAACAAGTGATTATCGGTGCCGCACCCTTTGACCATGTCGATGCTTGTAT
CGTGATGGGCGTCAATAGCGATGCTTTGACGCGTGATCTGCCTATTATCTCTAGCGTCTCTTGTACCACTCAGGCGCTCG
TACCGCTCATCGATACCCTTGACAAGGCGTTTGGTGTAGAGTCAGCTATGATGACTGAGATTCATGCAGTGACGGCTGAT
CAAACCGTACTTGACCAAGCGCACCGTGACCTAAGGCGTGCGCGCGCCTCTGGTTATAACATTATTCCGACGACTTCAAG
CAGTATCGCTGCTACGGAACGCGTGCTACCAAATATGGTGGGTAAGATAAATGGTCATTCTATTCGTGTGCCAACGATTG
ATGTTGCTGCGATTGATGTGACGTTTGTATTTGAGACGCCAAATGTCAGTATTGAAGCGATACGTGACGTTTTAAAATCA
GCGAGTCAGGCGCATTTAGCGACGATCATGGACTATACGGAGGAGCCGCTGGTCTCAAGTGACTTTATCCACCAGACTGA
ATCATTGATTATAGATGGGCAACAACTGATGCAAGTCGGCAATCAATACAAGGTTTTTGCTTGGTACGACAATGAATGGG
GCTATGCCAATCGCATGCTTGATATGTGCTTGCATCTTGCTTCAAACAAGCTTTAG

Upstream 100 bases:

>100_bases
TATTCGCGAACGACTATATTTTGCGTGGCGCTTTTTTGATCAGCCGATGGCATTCAATTTTAGCCTTCATTTTTTATTTC
TATTACAGCGATAACTTGTT

Downstream 100 bases:

>100_bases
ATTTATGATTACAAGCCGTTTAAAAAATAATTTAATTTTTTTGACATAACTGCTTGCATTCTCATTTCAGATCGCTATAA
TGATGCACAAATGGAGACGT

Product: glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: E4PDH [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MPDFSSATYRLTSNPATSGFHTTSDQTQPLRVAINGFGRIGRNVLRALLERFEVLGRAIHVVAINDLAPAETLLHLLRFD
STHGRLSQLGVTADIVQDGFTDHKQKPCATAKNDIQLCLTKNNLTYCIRLLSRENPETLPWKELQVDVVLECTGHYRSYE
QASLHIEAGAKQVIIGAAPFDHVDACIVMGVNSDALTRDLPIISSVSCTTQALVPLIDTLDKAFGVESAMMTEIHAVTAD
QTVLDQAHRDLRRARASGYNIIPTTSSSIAATERVLPNMVGKINGHSIRVPTIDVAAIDVTFVFETPNVSIEAIRDVLKS
ASQAHLATIMDYTEEPLVSSDFIHQTESLIIDGQQLMQVGNQYKVFAWYDNEWGYANRMLDMCLHLASNKL

Sequences:

>Translated_391_residues
MPDFSSATYRLTSNPATSGFHTTSDQTQPLRVAINGFGRIGRNVLRALLERFEVLGRAIHVVAINDLAPAETLLHLLRFD
STHGRLSQLGVTADIVQDGFTDHKQKPCATAKNDIQLCLTKNNLTYCIRLLSRENPETLPWKELQVDVVLECTGHYRSYE
QASLHIEAGAKQVIIGAAPFDHVDACIVMGVNSDALTRDLPIISSVSCTTQALVPLIDTLDKAFGVESAMMTEIHAVTAD
QTVLDQAHRDLRRARASGYNIIPTTSSSIAATERVLPNMVGKINGHSIRVPTIDVAAIDVTFVFETPNVSIEAIRDVLKS
ASQAHLATIMDYTEEPLVSSDFIHQTESLIIDGQQLMQVGNQYKVFAWYDNEWGYANRMLDMCLHLASNKL
>Mature_390_residues
PDFSSATYRLTSNPATSGFHTTSDQTQPLRVAINGFGRIGRNVLRALLERFEVLGRAIHVVAINDLAPAETLLHLLRFDS
THGRLSQLGVTADIVQDGFTDHKQKPCATAKNDIQLCLTKNNLTYCIRLLSRENPETLPWKELQVDVVLECTGHYRSYEQ
ASLHIEAGAKQVIIGAAPFDHVDACIVMGVNSDALTRDLPIISSVSCTTQALVPLIDTLDKAFGVESAMMTEIHAVTADQ
TVLDQAHRDLRRARASGYNIIPTTSSSIAATERVLPNMVGKINGHSIRVPTIDVAAIDVTFVFETPNVSIEAIRDVLKSA
SQAHLATIMDYTEEPLVSSDFIHQTESLIIDGQQLMQVGNQYKVFAWYDNEWGYANRMLDMCLHLASNKL

Specific function: Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=364, Percent_Identity=34.3406593406593, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI7657116, Length=363, Percent_Identity=34.435261707989, Blast_Score=212, Evalue=4e-55,
Organism=Escherichia coli, GI1789295, Length=362, Percent_Identity=41.9889502762431, Blast_Score=268, Evalue=6e-73,
Organism=Escherichia coli, GI1788079, Length=360, Percent_Identity=35.2777777777778, Blast_Score=223, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17534677, Length=361, Percent_Identity=34.6260387811634, Blast_Score=224, Evalue=6e-59,
Organism=Caenorhabditis elegans, GI17534679, Length=361, Percent_Identity=34.9030470914127, Blast_Score=224, Evalue=7e-59,
Organism=Caenorhabditis elegans, GI32566163, Length=366, Percent_Identity=35.2459016393443, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17568413, Length=361, Percent_Identity=35.1800554016621, Blast_Score=221, Evalue=4e-58,
Organism=Saccharomyces cerevisiae, GI6322468, Length=368, Percent_Identity=36.9565217391304, Blast_Score=242, Evalue=9e-65,
Organism=Saccharomyces cerevisiae, GI6321631, Length=365, Percent_Identity=37.2602739726027, Blast_Score=238, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6322409, Length=365, Percent_Identity=35.8904109589041, Blast_Score=233, Evalue=5e-62,
Organism=Drosophila melanogaster, GI85725000, Length=361, Percent_Identity=33.7950138504155, Blast_Score=211, Evalue=1e-54,
Organism=Drosophila melanogaster, GI22023983, Length=361, Percent_Identity=33.7950138504155, Blast_Score=211, Evalue=1e-54,
Organism=Drosophila melanogaster, GI17933600, Length=361, Percent_Identity=33.5180055401662, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI18110149, Length=361, Percent_Identity=33.5180055401662, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI19922412, Length=361, Percent_Identity=33.7950138504155, Blast_Score=198, Evalue=7e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006422
- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.72 [H]

Molecular weight: Translated: 43099; Mature: 42967

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDFSSATYRLTSNPATSGFHTTSDQTQPLRVAINGFGRIGRNVLRALLERFEVLGRAIH
CCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHEEE
VVAINDLAPAETLLHLLRFDSTHGRLSQLGVTADIVQDGFTDHKQKPCATAKNDIQLCLT
EEEECCCCHHHHHHHHHHCCCCCCHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEE
KNNLTYCIRLLSRENPETLPWKELQVDVVLECTGHYRSYEQASLHIEAGAKQVIIGAAPF
CCCHHHHHHHHHCCCCCCCCHHHEEEEEEEEECCCCCCCCCCEEEEECCCCEEEEECCCC
DHVDACIVMGVNSDALTRDLPIISSVSCTTQALVPLIDTLDKAFGVESAMMTEIHAVTAD
CCCCEEEEEECCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
QTVLDQAHRDLRRARASGYNIIPTTSSSIAATERVLPNMVGKINGHSIRVPTIDVAAIDV
HHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEECCEEEEEEEEE
TFVFETPNVSIEAIRDVLKSASQAHLATIMDYTEEPLVSSDFIHQTESLIIDGQQLMQVG
EEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHEECCHHHHHCC
NQYKVFAWYDNEWGYANRMLDMCLHLASNKL
CCEEEEEEECCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PDFSSATYRLTSNPATSGFHTTSDQTQPLRVAINGFGRIGRNVLRALLERFEVLGRAIH
CCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHEEE
VVAINDLAPAETLLHLLRFDSTHGRLSQLGVTADIVQDGFTDHKQKPCATAKNDIQLCLT
EEEECCCCHHHHHHHHHHCCCCCCHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEE
KNNLTYCIRLLSRENPETLPWKELQVDVVLECTGHYRSYEQASLHIEAGAKQVIIGAAPF
CCCHHHHHHHHHCCCCCCCCHHHEEEEEEEEECCCCCCCCCCEEEEECCCCEEEEECCCC
DHVDACIVMGVNSDALTRDLPIISSVSCTTQALVPLIDTLDKAFGVESAMMTEIHAVTAD
CCCCEEEEEECCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
QTVLDQAHRDLRRARASGYNIIPTTSSSIAATERVLPNMVGKINGHSIRVPTIDVAAIDV
HHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEECCEEEEEEEEE
TFVFETPNVSIEAIRDVLKSASQAHLATIMDYTEEPLVSSDFIHQTESLIIDGQQLMQVG
EEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHEECCHHHHHCC
NQYKVFAWYDNEWGYANRMLDMCLHLASNKL
CCEEEEEEECCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA