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The map label for this gene is gbh [H]

Identifier: 93006374

GI number: 93006374

Start: 1903070

End: 1904038

Strand: Reverse

Name: gbh [H]

Synonym: Pcryo_1550

Alternate gene names: 93006374

Gene position: 1904038-1903070 (Counterclockwise)

Preceding gene: 93006376

Following gene: 93006373

Centisome position: 62.23

GC content: 47.68

Gene sequence:

>969_bases
ATGAAATTCAATCAACCATTAAGCGGCAACGATATGCCAAGATTTGGCGGCTTTGCTTCTATGATGCGCCTGCCAACCCA
AGCCGATGCTGAAGGACTGGATGTAGCATTCGTTGGGGTGCCTTTAGATATTGGCGCATCAAACCGTAGCGGTGCAAGAT
TGGGACCACGCCAGATTCGCGATGAATCACGCATGATTCGCCCTTATAACGTCGCCACTCGCGCCGCTCCCTTTGAGTCT
TTGCAAGTCGCTGACATTGGCGACGTTCCTATCAATACCTTTAACCTGCTAAAAAGCGTCGATATTATTGAGAAATTCTA
TACCGATAAAATCGTCAGTCATGGCGCTATTCCTTTAACGTTAGGCGGCGATCATACGATTGCACTGCCTATTTTGCGTG
CGCTCGCCAAAAAACATGGCCCTGTTGGTATGGTGCATATCGATGCGCATGCCGATATCAATGATGAAATGTTTGGCGAA
AAAATTGCCCATGGTACGCCGTTCCGCCGCGCAGTTGAAGAGAACCTCATCGATGGTAATCGTGTGGTACAAATTGGTTT
ACGTGGTACGGGTTATAGTGCTGAAGAGTTTGATTGGTCAACCGAGCAAGGTTTTCGCGTAGTGCCTGCTGAAGAATGTT
GGTATAAATCGCTGACACCTTTGATGGCAGAAGTGCGCGAAAAATTAGGCGCTGGCCCTGTTTATTTAAGTTTTGATATT
GATGGTATTGATCCTGCTTTTGCACCGGGTACGGGAACCGCTGAAATTGGTGGCTTGACGTCAACGCAAGGTATTGAAAT
CATTCGTGGTATGCGTGGCCTTGATGTGGTCGGTGGTGATTTAGTAGAAGTGTCACCGCCGTATGACCCGTTTGGTAACA
CCTCGGTACTAGCCGCGAACCTGCTATTTGAGATGCTATGTATTCTACCGGGCGTGCGCTATGACGATAAGGTTAAAGCC
ATTTATTGA

Upstream 100 bases:

>100_bases
TCAGAGCTATAGAAAAAGTGGCATAGATAAAAAGTAATATAGACAAAAAGTAATATAGACAAATTGTCTGTTTTGACCAA
TCGATACAAGGATGTAAGTG

Downstream 100 bases:

>100_bases
AAATAATTTATAAACCCAAACTGTCCTTTATAGGGAATTAAAGGGCAGTTTGGGTTTAGCTTGGATTTGATATTGAACGA
CTTATTTAATTGCTATTGAA

Product: agmatinase

Products: NA

Alternate protein names: GBase; D-arginase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MKFNQPLSGNDMPRFGGFASMMRLPTQADAEGLDVAFVGVPLDIGASNRSGARLGPRQIRDESRMIRPYNVATRAAPFES
LQVADIGDVPINTFNLLKSVDIIEKFYTDKIVSHGAIPLTLGGDHTIALPILRALAKKHGPVGMVHIDAHADINDEMFGE
KIAHGTPFRRAVEENLIDGNRVVQIGLRGTGYSAEEFDWSTEQGFRVVPAEECWYKSLTPLMAEVREKLGAGPVYLSFDI
DGIDPAFAPGTGTAEIGGLTSTQGIEIIRGMRGLDVVGGDLVEVSPPYDPFGNTSVLAANLLFEMLCILPGVRYDDKVKA
IY

Sequences:

>Translated_322_residues
MKFNQPLSGNDMPRFGGFASMMRLPTQADAEGLDVAFVGVPLDIGASNRSGARLGPRQIRDESRMIRPYNVATRAAPFES
LQVADIGDVPINTFNLLKSVDIIEKFYTDKIVSHGAIPLTLGGDHTIALPILRALAKKHGPVGMVHIDAHADINDEMFGE
KIAHGTPFRRAVEENLIDGNRVVQIGLRGTGYSAEEFDWSTEQGFRVVPAEECWYKSLTPLMAEVREKLGAGPVYLSFDI
DGIDPAFAPGTGTAEIGGLTSTQGIEIIRGMRGLDVVGGDLVEVSPPYDPFGNTSVLAANLLFEMLCILPGVRYDDKVKA
IY
>Mature_322_residues
MKFNQPLSGNDMPRFGGFASMMRLPTQADAEGLDVAFVGVPLDIGASNRSGARLGPRQIRDESRMIRPYNVATRAAPFES
LQVADIGDVPINTFNLLKSVDIIEKFYTDKIVSHGAIPLTLGGDHTIALPILRALAKKHGPVGMVHIDAHADINDEMFGE
KIAHGTPFRRAVEENLIDGNRVVQIGLRGTGYSAEEFDWSTEQGFRVVPAEECWYKSLTPLMAEVREKLGAGPVYLSFDI
DGIDPAFAPGTGTAEIGGLTSTQGIEIIRGMRGLDVVGGDLVEVSPPYDPFGNTSVLAANLLFEMLCILPGVRYDDKVKA
IY

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=309, Percent_Identity=61.4886731391586, Blast_Score=393, Evalue=1e-109,
Organism=Homo sapiens, GI10947139, Length=281, Percent_Identity=27.7580071174377, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI1789306, Length=277, Percent_Identity=40.7942238267148, Blast_Score=183, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6325146, Length=203, Percent_Identity=30.5418719211823, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24638886, Length=187, Percent_Identity=30.4812834224599, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.7; =3.5.3.10 [H]

Molecular weight: Translated: 34874; Mature: 34874

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFNQPLSGNDMPRFGGFASMMRLPTQADAEGLDVAFVGVPLDIGASNRSGARLGPRQIR
CCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHH
DESRMIRPYNVATRAAPFESLQVADIGDVPINTFNLLKSVDIIEKFYTDKIVSHGAIPLT
HHHCCCCCCCCHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
LGGDHTIALPILRALAKKHGPVGMVHIDAHADINDEMFGEKIAHGTPFRRAVEENLIDGN
ECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCC
RVVQIGLRGTGYSAEEFDWSTEQGFRVVPAEECWYKSLTPLMAEVREKLGAGPVYLSFDI
EEEEEEECCCCCCHHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
DGIDPAFAPGTGTAEIGGLTSTQGIEIIRGMRGLDVVGGDLVEVSPPYDPFGNTSVLAAN
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCEECCCCEEECCCCCCCCCCHHHHHHH
LLFEMLCILPGVRYDDKVKAIY
HHHHHHHHCCCCCCCCCEEECC
>Mature Secondary Structure
MKFNQPLSGNDMPRFGGFASMMRLPTQADAEGLDVAFVGVPLDIGASNRSGARLGPRQIR
CCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHH
DESRMIRPYNVATRAAPFESLQVADIGDVPINTFNLLKSVDIIEKFYTDKIVSHGAIPLT
HHHCCCCCCCCHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
LGGDHTIALPILRALAKKHGPVGMVHIDAHADINDEMFGEKIAHGTPFRRAVEENLIDGN
ECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCC
RVVQIGLRGTGYSAEEFDWSTEQGFRVVPAEECWYKSLTPLMAEVREKLGAGPVYLSFDI
EEEEEEECCCCCCHHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
DGIDPAFAPGTGTAEIGGLTSTQGIEIIRGMRGLDVVGGDLVEVSPPYDPFGNTSVLAAN
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCEECCCCEEECCCCCCCCCCHHHHHHH
LLFEMLCILPGVRYDDKVKAIY
HHHHHHHHCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA