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The map label for this gene is nhaC [H]

Identifier: 93006376

GI number: 93006376

Start: 1905236

End: 1906660

Strand: Reverse

Name: nhaC [H]

Synonym: Pcryo_1552

Alternate gene names: 93006376

Gene position: 1906660-1905236 (Counterclockwise)

Preceding gene: 93006377

Following gene: 93006374

Centisome position: 62.31

GC content: 44.35

Gene sequence:

>1425_bases
ATGCCTCCAAAAATTCTAACCCAAATCTCACCGCAACTGGCATTTATGATTTCAGCCATTGTCATTGCTATCATGGGCGT
TACCATGATTGGCTTTGGCTGGGTACCGCATTTATCATTGATCCTCGCTATCTGTGTCCTGCTAGGCATTGGTATATTTA
AAGGATTAAGTTTTGATGACATGCAAGCGCAAATGGCATCCGGCGTTATGCGCGGTATTGGTGCGATCTATTTATTCTTC
TTTATCGGTTTGATGGTCGCCGCCTTAATGATGTCTGGTGCCATCCCAACGCTGATGTATTTCGGTTTTGAGCTGATATC
TCCGCAGTATTATTATATCTCCGCCTTTGTATTGACCTCTATTATTGGTATTGCTTTGGGCAGTAGTTTGACGACTGCTG
CGACGCTTGGCGTGGCTTTCATTGGTATGAGTGATGCCTTTGATGCTAACGTTGCGATAGCGGCAGGCGCTGTGGTATCA
GGGGCGTTTTTTGGTGATAAAATGTCGCCATTATCAGACACTTGTACCATTGCTTCAGCGGTTGTAGGCATCGATTTGTT
CGAGCATATACGCAATATGATGTATACTACAGTGCCGGCATGGATATTAACGGTTATATTATTTTGGTTTTTCTCAGGAC
AGACAGCTGGCTCAGATTTAAGTCAAGTAACGGTGCTAAAAGGACAATTGATTGACAGTGGTTTGGTACATGGTTATGCG
GTATTACCATTTGTGGTCTTGATTGCGCTGGCTCTATTTCGAGTTAATGCCATTTACACCATTATTTGTACCATTGCTGT
GGCAATTATCATTACTTATATGCATAGCACGCCAAACGTTGGGCAGTTGGGCGGTTATTTCTTTGCAGGTTATACACCCG
CAGAGTCATTGGAGCTTGGTGAAGTGGGCGGTATGCTGTCGCGTGGCGGTGTGCAAAGTATGTTCTTTACTCAAGCGATT
GTGATATTGGCGCTGAGTTTAGGCGGATTGCTGACGGCGTTGGGTATCTTGCCAGCATTGTTATCTGGTATTAAAGACAG
TTTAACGACAGCAGGACGCGCCATTTTTGCCGCTGCCATGTCAGCACTCAGTATCAATGTCCTTATCGGTGAGCAGTATT
TGAGTATTCTTTTATCGGGTACGGCATTTCGTCCGACGTTTGAGCGCTTGAACTTGCATCCAAAAAATCTATCACGCACC
ATTGAAGATGCCGGTACAGTGATCAATCCACTTGTACCATGGAGTGTGTGCGGTGTGTTTATCAGTCAAGCGTTAGGCGT
ACCAGTGCTTGATTATCTACCTTATGCGTTCTTCTGCTATTTATCATTGCTACTGACGATATTGTTTGGCTTTACAGGGA
TAACGATTACGCGTAAAGATGGGTCTAGCGTCCGTAAGCATCAAAAAGCGCAATCAGTTAATTAA

Upstream 100 bases:

>100_bases
CCAAATAATCAGAGTAGCAATACTGCTAGCAACTGATTAAACTTGTCACCCTAAAATCAAACCCTGTTGCCAGACTCTAC
TGGCACTCTAAGGATGTGTG

Downstream 100 bases:

>100_bases
ATAACGGCTACATAAACCCCTTTAAAGAATATTCATTCTTTAAAGGGGTTTTTTCGTAATAGGCTAATCATCTGCTCTAA
AAAATCAGCGACGTGCTTAT

Product: Na+/H+ antiporter NhaC

Products: NA

Alternate protein names: Sodium/hydrogen antiporter; Sodium/proton antiporter [H]

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MPPKILTQISPQLAFMISAIVIAIMGVTMIGFGWVPHLSLILAICVLLGIGIFKGLSFDDMQAQMASGVMRGIGAIYLFF
FIGLMVAALMMSGAIPTLMYFGFELISPQYYYISAFVLTSIIGIALGSSLTTAATLGVAFIGMSDAFDANVAIAAGAVVS
GAFFGDKMSPLSDTCTIASAVVGIDLFEHIRNMMYTTVPAWILTVILFWFFSGQTAGSDLSQVTVLKGQLIDSGLVHGYA
VLPFVVLIALALFRVNAIYTIICTIAVAIIITYMHSTPNVGQLGGYFFAGYTPAESLELGEVGGMLSRGGVQSMFFTQAI
VILALSLGGLLTALGILPALLSGIKDSLTTAGRAIFAAAMSALSINVLIGEQYLSILLSGTAFRPTFERLNLHPKNLSRT
IEDAGTVINPLVPWSVCGVFISQALGVPVLDYLPYAFFCYLSLLLTILFGFTGITITRKDGSSVRKHQKAQSVN

Sequences:

>Translated_474_residues
MPPKILTQISPQLAFMISAIVIAIMGVTMIGFGWVPHLSLILAICVLLGIGIFKGLSFDDMQAQMASGVMRGIGAIYLFF
FIGLMVAALMMSGAIPTLMYFGFELISPQYYYISAFVLTSIIGIALGSSLTTAATLGVAFIGMSDAFDANVAIAAGAVVS
GAFFGDKMSPLSDTCTIASAVVGIDLFEHIRNMMYTTVPAWILTVILFWFFSGQTAGSDLSQVTVLKGQLIDSGLVHGYA
VLPFVVLIALALFRVNAIYTIICTIAVAIIITYMHSTPNVGQLGGYFFAGYTPAESLELGEVGGMLSRGGVQSMFFTQAI
VILALSLGGLLTALGILPALLSGIKDSLTTAGRAIFAAAMSALSINVLIGEQYLSILLSGTAFRPTFERLNLHPKNLSRT
IEDAGTVINPLVPWSVCGVFISQALGVPVLDYLPYAFFCYLSLLLTILFGFTGITITRKDGSSVRKHQKAQSVN
>Mature_473_residues
PPKILTQISPQLAFMISAIVIAIMGVTMIGFGWVPHLSLILAICVLLGIGIFKGLSFDDMQAQMASGVMRGIGAIYLFFF
IGLMVAALMMSGAIPTLMYFGFELISPQYYYISAFVLTSIIGIALGSSLTTAATLGVAFIGMSDAFDANVAIAAGAVVSG
AFFGDKMSPLSDTCTIASAVVGIDLFEHIRNMMYTTVPAWILTVILFWFFSGQTAGSDLSQVTVLKGQLIDSGLVHGYAV
LPFVVLIALALFRVNAIYTIICTIAVAIIITYMHSTPNVGQLGGYFFAGYTPAESLELGEVGGMLSRGGVQSMFFTQAIV
ILALSLGGLLTALGILPALLSGIKDSLTTAGRAIFAAAMSALSINVLIGEQYLSILLSGTAFRPTFERLNLHPKNLSRTI
EDAGTVINPLVPWSVCGVFISQALGVPVLDYLPYAFFCYLSLLLTILFGFTGITITRKDGSSVRKHQKAQSVN

Specific function: Na(+)/H(+) antiporter. Involved in pH homeostasis and sodium extrusion [H]

COG id: COG1757

COG function: function code C; Na+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaC Na(+)/H(+) antiporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004770
- InterPro:   IPR018461 [H]

Pfam domain/function: PF03553 Na_H_antiporter [H]

EC number: NA

Molecular weight: Translated: 50317; Mature: 50186

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHCCCC
>Mature Secondary Structure 
PPKILTQISPQLAFMISAIVIAIMGVTMIGFGWVPHLSLILAICVLLGIGIFKGLSFDD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH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HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1660475; 9190799 [H]