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The map label for this gene is pdxA [H]

Identifier: 93006284

GI number: 93006284

Start: 1798120

End: 1799229

Strand: Reverse

Name: pdxA [H]

Synonym: Pcryo_1458

Alternate gene names: 93006284

Gene position: 1799229-1798120 (Counterclockwise)

Preceding gene: 93006288

Following gene: 93006282

Centisome position: 58.8

GC content: 44.41

Gene sequence:

>1110_bases
ATGCAAGAAAAATTGCCATTATTAATCACGACTGGTGAACCTGCGGGTATTGGTATGGATATCGTACTGCTGCTAGCGGC
TGAGGGTAAGTTACAGGATTTTGATCGTCCAGTTTGGGTCACAGCAGATAGCACGGCAATGCAAAAACGTGCCGATGAGC
TCATTGCTGCAGGCATACTAAAAAGCTGCCCACCTTGGAAAACGATCAATGCAAATGAGGCAATTATAGAAGACGATGAT
TTTTTAAATCAAATGTCACAGCAGAGTATTAACAGTGGCGCTATTAATAATGATAATGCTTTTATCTTATTAAATATTCC
CTGTGCTGCGCCCGTCGCTTGTGGGAAAATTGATATCAATAACTCCGCAATGGTGGTAACGCAGTTGGAAATAGCGCATA
AACTGGCAGCCAACAAAACAGTCGCCGCTATCGTCACCGGACCACTACAAAAATCTGCATTGATAGATGCTGGTATTAAA
CTGTTAGATGGCACGATGTTTAGTGGGCATACGGAATTTTTTATGCAGCAAAGTGGCTGTGATAAAGTCGTCATGATGCT
TGCTAATGAAGCCATGAAGGTGGCACTTGTTACAACGCACTTGGCATTAAAAGACGTGCCTGCAGCCATCACTGCCGATA
ACGTACGCCAAACAGTGCAAATTGTTATCGATGATATGTGTAAGAAATTTGGCTTGACGCAGCCGCGTATCTTAGTTTGC
GGTCTAAATCCGCATGCGGGCGAGGGCGGGCATTTGGGCATTGAGGAGATTGAGATTATCAATCCAGTGCTACAAGAATT
TATCAATATTGGGATAGATATATCAGAGGCGATGCCAGCGGATACTTTATTCACGCCGAGACATTTAGCCAACTGCGATG
CAGTGATTGCCATGTATCACGACCAAGGGTTGCCTGTACTCAAGTCACATGGCTTTGGTGATACAGTCAATTTGACTTTG
GGACTGCCTTATATTCGTACTTCTGTCGATCACGGTACTGCGCTTGATTTGGCAGGACGTGGCGGTGCTAGTGCCACCAG
CCTATACCAAGCACTCATCATGGCAAATGAGATGGCCGATAAATCGCTTATTGATAGACTTCTTGTATAA

Upstream 100 bases:

>100_bases
AATGAAGTTCATGGCATATAACACAGCTTAAAATACGCTCATTTATCATAAAAAATACAATAGAATCAGCTTCTTAATAT
AATAATAGGATGTTAGTGCT

Downstream 100 bases:

>100_bases
GTCGATACTTTGGCGAGATTTGTCACTCAGTATTGGATAACGTTACCGTCAGTAATACCTATTTATGAATCATCAAACAC
GCCTTAATATAAGTGGTTCC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MQEKLPLLITTGEPAGIGMDIVLLLAAEGKLQDFDRPVWVTADSTAMQKRADELIAAGILKSCPPWKTINANEAIIEDDD
FLNQMSQQSINSGAINNDNAFILLNIPCAAPVACGKIDINNSAMVVTQLEIAHKLAANKTVAAIVTGPLQKSALIDAGIK
LLDGTMFSGHTEFFMQQSGCDKVVMMLANEAMKVALVTTHLALKDVPAAITADNVRQTVQIVIDDMCKKFGLTQPRILVC
GLNPHAGEGGHLGIEEIEIINPVLQEFINIGIDISEAMPADTLFTPRHLANCDAVIAMYHDQGLPVLKSHGFGDTVNLTL
GLPYIRTSVDHGTALDLAGRGGASATSLYQALIMANEMADKSLIDRLLV

Sequences:

>Translated_369_residues
MQEKLPLLITTGEPAGIGMDIVLLLAAEGKLQDFDRPVWVTADSTAMQKRADELIAAGILKSCPPWKTINANEAIIEDDD
FLNQMSQQSINSGAINNDNAFILLNIPCAAPVACGKIDINNSAMVVTQLEIAHKLAANKTVAAIVTGPLQKSALIDAGIK
LLDGTMFSGHTEFFMQQSGCDKVVMMLANEAMKVALVTTHLALKDVPAAITADNVRQTVQIVIDDMCKKFGLTQPRILVC
GLNPHAGEGGHLGIEEIEIINPVLQEFINIGIDISEAMPADTLFTPRHLANCDAVIAMYHDQGLPVLKSHGFGDTVNLTL
GLPYIRTSVDHGTALDLAGRGGASATSLYQALIMANEMADKSLIDRLLV
>Mature_369_residues
MQEKLPLLITTGEPAGIGMDIVLLLAAEGKLQDFDRPVWVTADSTAMQKRADELIAAGILKSCPPWKTINANEAIIEDDD
FLNQMSQQSINSGAINNDNAFILLNIPCAAPVACGKIDINNSAMVVTQLEIAHKLAANKTVAAIVTGPLQKSALIDAGIK
LLDGTMFSGHTEFFMQQSGCDKVVMMLANEAMKVALVTTHLALKDVPAAITADNVRQTVQIVIDDMCKKFGLTQPRILVC
GLNPHAGEGGHLGIEEIEIINPVLQEFINIGIDISEAMPADTLFTPRHLANCDAVIAMYHDQGLPVLKSHGFGDTVNLTL
GLPYIRTSVDHGTALDLAGRGGASATSLYQALIMANEMADKSLIDRLLV

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=353, Percent_Identity=46.4589235127479, Blast_Score=280, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 39429; Mature: 39429

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEKLPLLITTGEPAGIGMDIVLLLAAEGKLQDFDRPVWVTADSTAMQKRADELIAAGIL
CCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHH
KSCPPWKTINANEAIIEDDDFLNQMSQQSINSGAINNDNAFILLNIPCAAPVACGKIDIN
HCCCCCCCCCCCCCEECCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCEEEEC
NSAMVVTQLEIAHKLAANKTVAAIVTGPLQKSALIDAGIKLLDGTMFSGHTEFFMQQSGC
CCEEEEEEHHHHHHHHCCCEEEEEEECCCHHHHHHHHCHHHHCCCEECCCHHHHHHHCCC
DKVVMMLANEAMKVALVTTHLALKDVPAAITADNVRQTVQIVIDDMCKKFGLTQPRILVC
HHHHHHHHCCHHEEEEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
GLNPHAGEGGHLGIEEIEIINPVLQEFINIGIDISEAMPADTLFTPRHLANCDAVIAMYH
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCHHHCCCCEEEEEEE
DQGLPVLKSHGFGDTVNLTLGLPYIRTSVDHGTALDLAGRGGASATSLYQALIMANEMAD
CCCCCEEECCCCCCEEEEEECCCHHEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHH
KSLIDRLLV
HHHHHHHCC
>Mature Secondary Structure
MQEKLPLLITTGEPAGIGMDIVLLLAAEGKLQDFDRPVWVTADSTAMQKRADELIAAGIL
CCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHH
KSCPPWKTINANEAIIEDDDFLNQMSQQSINSGAINNDNAFILLNIPCAAPVACGKIDIN
HCCCCCCCCCCCCCEECCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCEEEEC
NSAMVVTQLEIAHKLAANKTVAAIVTGPLQKSALIDAGIKLLDGTMFSGHTEFFMQQSGC
CCEEEEEEHHHHHHHHCCCEEEEEEECCCHHHHHHHHCHHHHCCCEECCCHHHHHHHCCC
DKVVMMLANEAMKVALVTTHLALKDVPAAITADNVRQTVQIVIDDMCKKFGLTQPRILVC
HHHHHHHHCCHHEEEEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
GLNPHAGEGGHLGIEEIEIINPVLQEFINIGIDISEAMPADTLFTPRHLANCDAVIAMYH
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCHHHCCCCEEEEEEE
DQGLPVLKSHGFGDTVNLTLGLPYIRTSVDHGTALDLAGRGGASATSLYQALIMANEMAD
CCCCCEEECCCCCCEEEEEECCCHHEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHH
KSLIDRLLV
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA