Click here to switch to the map view.

The map label for this gene is rpiA [H]

Identifier: 93006288

GI number: 93006288

Start: 1803427

End: 1804086

Strand: Reverse

Name: rpiA [H]

Synonym: Pcryo_1462

Alternate gene names: 93006288

Gene position: 1804086-1803427 (Counterclockwise)

Preceding gene: 93006289

Following gene: 93006284

Centisome position: 58.96

GC content: 46.36

Gene sequence:

>660_bases
ATGAGTGATCAGCAAGCACAAAAGCAAGCCGCCGCCCGCGCCGCCTTACGCTATATCGAAGATGATATGATACTTGGCGT
AGGGACAGGAAGTACAGTGAACTGTCTGATTGAGTTATTACCAACAGTAAAGCTCGCTGGCGCAGTTGCAAGTTCACAGG
TGACAGAAGATAGATTGCGTGCACTTGGTATCGAAATTGTTGACTTAAATTTTGCCGGTCAGCTCGATGTATATATTGAT
GGTGCTGATGAAGTAAACGCGCATTTGCAACTGATTAAAGGTGGCGGTGGTGCGCTCACGCGTGAAAAAATCGTTGCCGC
GGCATCGAACAAATTTGTTTGTATGGTTGACGCCAGTAAAAGTGTCGAGATACTAGGGCGCGAATTCCCAGTGCCGATAG
AGGTATTGCCACAAGCCCGCTCATATGTGGCGCGCGAGTTGGCCAAAATGGGCGGTGAGCCTGTTTATCGTGAAGACTTT
GTCACCGATTATGGCAATGTGATTTTGGATACTTATGATTTAGATGTCAGTAATCCAATAGCACTTGAACAGCAGCTTAA
TAATATCGTCGGTGTGGTCTGTAATGGTATCTTTGCTGCCAATCAAGCCGATGTGTTGTTAAAAGCCAGCAGTAATGGGG
TTGAAGTGCTGACTCGATAA

Upstream 100 bases:

>100_bases
TGACATCCATCAAATTCATCGGTTATAATAGCGGCGCATTTTACCTCTTTTACCCTTTACTTTTTTTAAAGCGATACGTT
TATTTTGCCAAGGACTTATG

Downstream 100 bases:

>100_bases
TCAATAAGCGCTTGTCTATTAGACACTAACTTGGTTATCACATATTAAAAAAGGCAGAGCACAAGTTATGTGCTCTGCCT
TTTTGATATTTATGACTGTA

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSDQQAQKQAAARAALRYIEDDMILGVGTGSTVNCLIELLPTVKLAGAVASSQVTEDRLRALGIEIVDLNFAGQLDVYID
GADEVNAHLQLIKGGGGALTREKIVAAASNKFVCMVDASKSVEILGREFPVPIEVLPQARSYVARELAKMGGEPVYREDF
VTDYGNVILDTYDLDVSNPIALEQQLNNIVGVVCNGIFAANQADVLLKASSNGVEVLTR

Sequences:

>Translated_219_residues
MSDQQAQKQAAARAALRYIEDDMILGVGTGSTVNCLIELLPTVKLAGAVASSQVTEDRLRALGIEIVDLNFAGQLDVYID
GADEVNAHLQLIKGGGGALTREKIVAAASNKFVCMVDASKSVEILGREFPVPIEVLPQARSYVARELAKMGGEPVYREDF
VTDYGNVILDTYDLDVSNPIALEQQLNNIVGVVCNGIFAANQADVLLKASSNGVEVLTR
>Mature_218_residues
SDQQAQKQAAARAALRYIEDDMILGVGTGSTVNCLIELLPTVKLAGAVASSQVTEDRLRALGIEIVDLNFAGQLDVYIDG
ADEVNAHLQLIKGGGGALTREKIVAAASNKFVCMVDASKSVEILGREFPVPIEVLPQARSYVARELAKMGGEPVYREDFV
TDYGNVILDTYDLDVSNPIALEQQLNNIVGVVCNGIFAANQADVLLKASSNGVEVLTR

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=213, Percent_Identity=35.6807511737089, Blast_Score=102, Evalue=4e-22,
Organism=Escherichia coli, GI1789280, Length=218, Percent_Identity=50.9174311926605, Blast_Score=227, Evalue=5e-61,
Organism=Caenorhabditis elegans, GI17551758, Length=227, Percent_Identity=37.8854625550661, Blast_Score=119, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6324669, Length=255, Percent_Identity=30.1960784313725, Blast_Score=89, Evalue=6e-19,
Organism=Drosophila melanogaster, GI281364072, Length=219, Percent_Identity=36.0730593607306, Blast_Score=88, Evalue=4e-18,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 23380; Mature: 23249

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQQAQKQAAARAALRYIEDDMILGVGTGSTVNCLIELLPTVKLAGAVASSQVTEDRLR
CCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGIEIVDLNFAGQLDVYIDGADEVNAHLQLIKGGGGALTREKIVAAASNKFVCMVDASK
HCCEEEEEEECCCEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHEECCCCEEEEEECCC
SVEILGREFPVPIEVLPQARSYVARELAKMGGEPVYREDFVTDYGNVILDTYDLDVSNPI
CCEECCCCCCCCHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEECCCCCCC
ALEQQLNNIVGVVCNGIFAANQADVLLKASSNGVEVLTR
HHHHHHHHHHHHHHCCCEECCCCEEEEEECCCCEEEEEC
>Mature Secondary Structure 
SDQQAQKQAAARAALRYIEDDMILGVGTGSTVNCLIELLPTVKLAGAVASSQVTEDRLR
CCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGIEIVDLNFAGQLDVYIDGADEVNAHLQLIKGGGGALTREKIVAAASNKFVCMVDASK
HCCEEEEEEECCCEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHEECCCCEEEEEECCC
SVEILGREFPVPIEVLPQARSYVARELAKMGGEPVYREDFVTDYGNVILDTYDLDVSNPI
CCEECCCCCCCCHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEECCCCCCC
ALEQQLNNIVGVVCNGIFAANQADVLLKASSNGVEVLTR
HHHHHHHHHHHHHHCCCEECCCCEEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA