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The map label for this gene is dsbE [H]

Identifier: 93006177

GI number: 93006177

Start: 1651585

End: 1652247

Strand: Direct

Name: dsbE [H]

Synonym: Pcryo_1349

Alternate gene names: 93006177

Gene position: 1651585-1652247 (Clockwise)

Preceding gene: 93006176

Following gene: 93006178

Centisome position: 53.98

GC content: 42.23

Gene sequence:

>663_bases
ATGACTATGTCGAATAATACTCCTGAGCAAAAAGATAGCCAAAACAGTAAGCAGCGTAACCCAAAGACAATGAAAAAAAA
GCAGACGAAGCTATGGTTCTTAATTCCGCTTATCCTCTTTTTTGGTTTGGTAGTTATATTGTACATGCGCTTAGGTAAAC
CAACAGACATTGTGACCAATACCGCTCTTGAGCGTCCGGTTCCTACCTTTGAGCTGCCGTTATTAGCAGATACTACCCGT
ACTATCACCAATGATAATTTGCCAGATAAGCCGTTTTTACTTAATGTTTGGGGCTCATGGTGCCCAACTTGCGTTATTGA
GCATCCGTTTTTAATGCAACTAGAAGAGCGCGGCGTTGATATCGTTGGTGTGAATTATAAGGATGAGATTGGTAATGCGC
TCAGTTACTTAAACCGAGGCGGTGATCCATTTTCTATGTCTATTCAGGATTCATTGGGTCAGTTTGCTCTAGACTTAGGC
ATAACTGGTGCGCCCGAAACCTTTGTTGTGGATGGAGATGGCATCATTCGTCAGCATATTGTTGGTGAGATTAATGAAGC
CAATTGGCAACAGCGTGTTAAGCCGTGCCTGACAGTACTTAATAAGGCTAATAAGAACAACGATAGTCCTGATCTCATTC
AGGTTGAGGAGATGTGCAAATGA

Upstream 100 bases:

>100_bases
ATTGCTAGTTACTGGTGATCTGGCTACTGATGGAGTCAATGAGGTAGCTATTGAGCAGGCAATCTCAGCATCGACGATGT
CGACACTAAAGGAGAAATAA

Downstream 100 bases:

>100_bases
ACGTTACTCGAATAAGAGCTCCTCAACTAAAACCCAATATAGTTTTAAAAATAGCAAGCTTAATACTAGCGTGTCTGCTT
AACATGACGGCAAACGCAGC

Product: periplasmic protein thiol

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CcmG [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MTMSNNTPEQKDSQNSKQRNPKTMKKKQTKLWFLIPLILFFGLVVILYMRLGKPTDIVTNTALERPVPTFELPLLADTTR
TITNDNLPDKPFLLNVWGSWCPTCVIEHPFLMQLEERGVDIVGVNYKDEIGNALSYLNRGGDPFSMSIQDSLGQFALDLG
ITGAPETFVVDGDGIIRQHIVGEINEANWQQRVKPCLTVLNKANKNNDSPDLIQVEEMCK

Sequences:

>Translated_220_residues
MTMSNNTPEQKDSQNSKQRNPKTMKKKQTKLWFLIPLILFFGLVVILYMRLGKPTDIVTNTALERPVPTFELPLLADTTR
TITNDNLPDKPFLLNVWGSWCPTCVIEHPFLMQLEERGVDIVGVNYKDEIGNALSYLNRGGDPFSMSIQDSLGQFALDLG
ITGAPETFVVDGDGIIRQHIVGEINEANWQQRVKPCLTVLNKANKNNDSPDLIQVEEMCK
>Mature_219_residues
TMSNNTPEQKDSQNSKQRNPKTMKKKQTKLWFLIPLILFFGLVVILYMRLGKPTDIVTNTALERPVPTFELPLLADTTRT
ITNDNLPDKPFLLNVWGSWCPTCVIEHPFLMQLEERGVDIVGVNYKDEIGNALSYLNRGGDPFSMSIQDSLGQFALDLGI
TGAPETFVVDGDGIIRQHIVGEINEANWQQRVKPCLTVLNKANKNNDSPDLIQVEEMCK

Specific function: Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=176, Percent_Identity=41.4772727272727, Blast_Score=144, Evalue=6e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 24791; Mature: 24660

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMSNNTPEQKDSQNSKQRNPKTMKKKQTKLWFLIPLILFFGLVVILYMRLGKPTDIVTN
CCCCCCCCCCHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
TALERPVPTFELPLLADTTRTITNDNLPDKPFLLNVWGSWCPTCVIEHPFLMQLEERGVD
HHHHCCCCCCCCCEECCCCHHHCCCCCCCCCEEEECCCCCCCHHHHCCHHHHHHHHCCCE
IVGVNYKDEIGNALSYLNRGGDPFSMSIQDSLGQFALDLGITGAPETFVVDGDGIIRQHI
EEECCCHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHH
VGEINEANWQQRVKPCLTVLNKANKNNDSPDLIQVEEMCK
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHCC
>Mature Secondary Structure 
TMSNNTPEQKDSQNSKQRNPKTMKKKQTKLWFLIPLILFFGLVVILYMRLGKPTDIVTN
CCCCCCCCCHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
TALERPVPTFELPLLADTTRTITNDNLPDKPFLLNVWGSWCPTCVIEHPFLMQLEERGVD
HHHHCCCCCCCCCEECCCCHHHCCCCCCCCCEEEECCCCCCCHHHHCCHHHHHHHHCCCE
IVGVNYKDEIGNALSYLNRGGDPFSMSIQDSLGQFALDLGITGAPETFVVDGDGIIRQHI
EEECCCHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHH
VGEINEANWQQRVKPCLTVLNKANKNNDSPDLIQVEEMCK
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]